[Hub]/) : Traits : Trunk fat percentage : ← →

chr16:69,062,879-70,978,362

Best TWAS P=8.23e-18 · Best GWAS P=3.85e-18 conditioned to 0.0831

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	WWP2	0.10	0.04	bslmm	274	0.06	4.4e-08	-6.11	6.0	1.8e-09	0.29	0.98	0.00	FALSE
2	GTEx	Adipose Subcutaneous	EXOSC6	0.27	0.28	enet	26	0.32	3.1e-27	-4.89	-5.6	2.0e-08	-0.22	1.00	0.00	FALSE
3	GTEx	Adipose Visceral Omentum	EXOSC6	0.26	0.29	lasso	6	0.32	3.3e-17	-4.89	-5.2	2.2e-07	-0.20	1.00	0.00	FALSE
4	GTEx	Adrenal Gland	EXOSC6	0.22	0.18	enet	6	0.17	1.1e-06	-4.89	-5.3	1.2e-07	-0.14	0.82	0.01	FALSE
5	GTEx	Artery Tibial	WWP2	0.13	0.01	enet	17	0.02	4.9e-03	-6.29	6.3	3.3e-10	0.32	0.49	0.07	FALSE
6	GTEx	Artery Tibial	EXOSC6	0.27	0.32	enet	10	0.30	5.5e-24	-4.88	-5.1	2.7e-07	-0.15	1.00	0.00	FALSE
7	GTEx	Brain Cerebellar Hemisphere	PDXDC2P	0.33	0.16	enet	11	0.27	1.4e-07	-6.23	-5.8	5.6e-09	-0.35	0.61	0.09	FALSE
8	GTEx	Brain Cerebellar Hemisphere	EXOSC6	0.51	0.15	lasso	11	0.26	2.9e-07	-4.88	-6.1	9.0e-10	-0.33	0.48	0.26	FALSE
9	GTEx	Brain Cerebellum	PDPR	0.23	0.06	enet	20	0.11	3.7e-04	-4.85	-7.8	7.5e-15	-0.30	0.07	0.25	FALSE
10	GTEx	Brain Cerebellum	RP11-296I10.3	0.20	0.03	enet	12	0.14	8.8e-05	-4.88	-8.6	8.2e-18	-0.36	0.04	0.27	TRUE
11	GTEx	Brain Hippocampus	EXOSC6	0.17	0.06	lasso	4	0.03	6.7e-02	-4.85	-5.4	5.9e-08	-0.22	0.05	0.07	FALSE
12	GTEx	Brain Nucleus accumbens basal ganglia	RP11-296I10.6	0.15	0.11	lasso	3	0.08	3.0e-03	-4.89	-6.2	7.1e-10	-0.28	0.12	0.12	FALSE
13	GTEx	Breast Mammary Tissue	RP11-296I10.6	0.31	0.30	enet	17	0.30	7.1e-16	-4.88	-5.2	1.9e-07	-0.12	1.00	0.00	FALSE
14	GTEx	Breast Mammary Tissue (Female)	EXOSC6	0.52	0.26	enet	21	0.27	1.4e-08	-4.85	-7.0	1.7e-12	-0.33	0.69	0.16	FALSE
15	GTEx	Breast Mammary Tissue (Female)	RP11-296I10.6	0.18	0.17	enet	8	0.13	1.0e-04	-4.85	-5.3	9.2e-08	-0.20	0.33	0.08	FALSE
16	GTEx	Cells Transformed fibroblasts	RP11-296I10.6	0.10	0.09	enet	9	0.10	6.1e-08	-4.88	-5.6	2.5e-08	-0.19	1.00	0.00	FALSE
17	GTEx	Colon Sigmoid	RP11-296I10.6	0.32	0.33	enet	20	0.33	2.2e-12	-4.88	-5.2	1.8e-07	-0.13	1.00	0.00	FALSE
18	GTEx	Heart Atrial Appendage	RP11-296I10.6	0.18	0.19	enet	16	0.16	1.1e-07	-4.88	-5.7	1.1e-08	-0.18	0.99	0.00	FALSE
19	GTEx	Muscle Skeletal	EXOSC6	0.28	0.32	enet	20	0.32	4.2e-32	-4.88	-5.2	2.7e-07	-0.18	1.00	0.00	FALSE
20	GTEx	Muscle Skeletal	RP11-296I10.6	0.11	0.15	enet	16	0.15	1.8e-14	-4.89	-5.2	1.5e-07	-0.20	1.00	0.00	FALSE
21	GTEx	Nerve Tibial	RP11-296I10.6	0.32	0.40	enet	23	0.43	5.1e-33	-4.89	-5.2	1.9e-07	-0.16	1.00	0.00	FALSE
22	GTEx	Ovary	RP11-296I10.6	0.35	0.28	enet	18	0.27	2.2e-07	-4.85	-6.9	5.4e-12	-0.46	0.15	0.68	FALSE
23	GTEx	Stomach	RP11-296I10.6	0.24	0.15	enet	14	0.16	4.5e-08	-4.88	-5.3	1.2e-07	-0.16	1.00	0.00	FALSE
24	GTEx	Testis	WWP2	0.30	0.10	lasso	5	0.16	9.2e-08	5.61	7.6	3.0e-14	0.68	0.32	0.53	FALSE
25	GTEx	Thyroid	NOB1	0.03	0.01	enet	6	0.02	7.7e-03	7.00	-7.9	2.5e-15	-0.76	0.24	0.24	FALSE
26	GTEx	Thyroid	CTD-2033A16.3	0.03	0.02	enet	7	0.02	6.7e-03	5.07	-7.3	3.7e-13	-0.72	0.20	0.29	FALSE
27	GTEx	Whole Blood	RP11-296I10.6	0.08	0.07	enet	16	0.09	2.3e-08	-4.88	-5.3	1.3e-07	-0.19	1.00	0.00	FALSE
28	METSIM	Adipose	CLEC18A	0.26	0.18	lasso	15	0.27	4.4e-40	3.65	-5.9	3.9e-09	-0.31	1.00	0.00	FALSE
29	METSIM	Adipose	NOB1	0.03	0.03	lasso	2	0.03	2.8e-05	3.87	-5.2	1.7e-07	-0.57	0.22	0.75	FALSE
30	NTR	Blood	EXOSC6	0.06	0.07	bslmm	195	0.07	2.7e-22	-4.89	-5.6	2.1e-08	-0.18	1.00	0.00	FALSE
31	ROSMAP	Brain Pre-frontal Cortex	RP11-296I10.6	0.36	0.42	enet	19	0.42	6.7e-59	-4.87	-5.3	1.3e-07	-0.16	1.00	0.00	FALSE
32	YFS	Blood	EXOSC6	0.24	0.24	lasso	5	0.25	2.4e-81	-4.89	-5.2	1.6e-07	-0.16	1.00	0.00	FALSE
33	YFS	Blood	PDPR	0.02	0.00	enet	20	0.01	1.8e-05	-0.42	6.2	7.6e-10	0.55	0.02	0.63	FALSE
34	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PDXDC2	0.06	0.02	blup	26	0.06	9.7e-06	-6.23	-5.2	1.8e-07	-0.36	0.02	0.96	FALSE
35	The Cancer Genome Atlas	Breast Invasive Carcinoma	CLEC18A	0.16	0.17	enet	10	0.19	6.8e-37	-6.11	-5.7	1.5e-08	-0.41	0.40	0.60	FALSE
36	The Cancer Genome Atlas	Breast Invasive Carcinoma	NFAT5	0.02	0.01	enet	5	0.01	6.6e-04	4.99	8.5	1.7e-17	0.76	0.02	0.55	FALSE
37	The Cancer Genome Atlas	Breast Invasive Carcinoma	NQO1	0.02	0.01	blup	39	0.01	4.3e-03	5.41	6.3	3.9e-10	0.73	0.06	0.16	TRUE
38	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	CLEC18A	0.10	0.06	lasso	2	0.04	6.3e-03	-6.11	-6.1	1.0e-09	-0.43	0.04	0.25	FALSE
39	The Cancer Genome Atlas	Colon Adenocarcinoma	CLEC18A	0.14	0.18	lasso	5	0.15	4.5e-09	-6.11	-6.2	5.7e-10	-0.45	0.26	0.74	FALSE
40	The Cancer Genome Atlas	Colon Adenocarcinoma	NQO1	0.06	0.04	lasso	3	0.01	5.3e-02	5.41	5.4	8.0e-08	0.53	0.04	0.07	FALSE
41	The Cancer Genome Atlas	Esophageal Carcinoma	CLEC18A	0.19	0.04	blup	23	0.10	3.6e-04	-6.22	-5.4	6.9e-08	-0.33	0.01	0.40	FALSE
42	The Cancer Genome Atlas	Glioblastoma Multiforme	PDXDC2	0.10	0.12	lasso	3	0.10	4.7e-04	-6.11	-6.1	1.0e-09	-0.43	0.01	0.83	FALSE
43	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	AARS	0.02	0.01	enet	4	0.01	5.3e-02	-4.87	5.3	1.1e-07	0.05	0.00	0.38	FALSE
44	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CLEC18A	0.20	0.12	lasso	3	0.15	2.7e-16	-6.29	-6.2	5.1e-10	-0.36	0.21	0.79	FALSE
45	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	AARS	0.05	0.02	enet	6	0.03	9.8e-03	-4.87	5.4	7.0e-08	0.15	0.00	0.38	FALSE
46	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	EXOSC6	0.17	0.17	enet	5	0.17	9.2e-10	-4.87	-5.4	6.5e-08	-0.17	0.00	0.99	FALSE
47	The Cancer Genome Atlas	Lung Adenocarcinoma	CLEC18A	0.13	0.17	enet	11	0.17	1.8e-19	-6.11	-6.1	1.1e-09	-0.39	0.30	0.70	FALSE
48	The Cancer Genome Atlas	Lung Adenocarcinoma	EXOSC6	0.09	0.13	enet	5	0.13	4.2e-15	-4.87	-5.2	1.8e-07	-0.16	0.00	0.99	FALSE
49	The Cancer Genome Atlas	Lung Adenocarcinoma	PDXDC2	0.10	0.10	blup	26	0.11	6.7e-13	3.60	-5.2	2.0e-07	-0.31	0.14	0.86	FALSE
50	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CLEC18A	0.06	0.10	lasso	1	0.09	6.9e-11	-6.22	-6.2	4.8e-10	-0.42	0.27	0.73	FALSE
51	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PDXDC2	0.09	0.05	blup	26	0.07	2.5e-08	-3.56	-5.2	2.4e-07	-0.35	0.02	0.98	FALSE
52	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CLEC18A	0.21	0.08	blup	23	0.12	9.8e-06	-3.62	-5.4	5.6e-08	-0.32	0.06	0.32	FALSE
53	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CLEC18A	0.20	0.14	enet	12	0.15	1.5e-06	-6.22	-6.0	1.7e-09	-0.39	0.22	0.67	FALSE
54	The Cancer Genome Atlas	Rectum Adenocarcinoma	CLEC18A	0.15	0.03	blup	23	0.09	4.3e-03	-3.62	-6.6	3.2e-11	-0.57	0.01	0.33	FALSE
55	The Cancer Genome Atlas	Soft Tissue Sarcoma	CLEC18A	0.12	0.11	lasso	2	0.11	3.4e-07	-6.23	-6.2	4.6e-10	-0.46	0.26	0.74	FALSE
56	The Cancer Genome Atlas	Skin Cutaneous Melanoma	CLEC18A	0.17	0.09	enet	8	0.11	8.5e-04	-3.62	-6.0	2.1e-09	-0.52	0.02	0.70	FALSE
57	The Cancer Genome Atlas	Stomach Adenocarcinoma	CLEC18A	0.07	0.05	blup	23	0.04	3.7e-04	-6.23	-6.5	5.7e-11	-0.40	0.15	0.48	FALSE
58	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CLEC18A	0.20	0.09	lasso	5	0.08	8.8e-04	-6.60	-6.7	3.0e-11	-0.59	0.01	0.85	FALSE
59	The Cancer Genome Atlas	Thyroid Carcinoma	CLEC18A	0.24	0.26	blup	23	0.27	1.3e-26	-6.23	-5.5	3.9e-08	-0.36	0.24	0.76	FALSE