Best TWAS P=6.94e-10 · Best GWAS P=1.08e-08 conditioned to 0.0889
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Caudate basal ganglia | DMGDH | 0.25 | 0.08 | enet | 23 | 0.15 | 3.5e-05 | -3.1 | -5.3 | 1.1e-07 | -0.05 | 0.02 | 0.07 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | AP3B1 | 0.02 | 0.00 | blup | 126 | 0.01 | 1.8e-02 | -5.7 | -5.9 | 3.9e-09 | 0.85 | 0.02 | 0.89 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | AP3B1 | 0.05 | 0.02 | blup | 126 | 0.03 | 5.0e-04 | 5.1 | -6.2 | 6.9e-10 | 0.81 | 0.02 | 0.91 | TRUE |