TWAS hub - DMGDH

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1300	0.0310	1.2e-11	0.127	0.122	0.125	0.128	0.124	3.2e-15	1.4e-14	5.7e-15	2.9e-15	6.7e-15
2	GTEx	Adipose Subcutaneous	0.1340	0.0580	6.1e-03	0.002	NA	0.017	NA	-0.003	2.3e-01	NA	1.4e-02	NA	9.1e-01
3	GTEx	Brain Caudate basal ganglia	0.2550	0.1000	4.5e-03	0.076	NA	0.154	NA	0.027	3.4e-03	NA	3.5e-05	NA	5.8e-02
4	GTEx	Brain Frontal Cortex BA9	0.2749	0.0874	6.1e-04	0.081	NA	0.173	NA	0.097	3.7e-03	NA	2.4e-05	NA	1.5e-03
5	GTEx	Cells Transformed fibroblasts	0.1480	0.0420	2.3e-06	0.140	NA	0.093	NA	0.127	1.1e-10	NA	2.0e-07	NA	9.8e-10
6	GTEx	Colon Sigmoid	0.1800	0.0780	4.2e-03	0.037	NA	0.026	NA	0.043	1.8e-02	NA	4.2e-02	NA	1.2e-02
7	GTEx	Heart Atrial Appendage	0.1860	0.0560	7.8e-05	0.061	NA	0.136	NA	0.140	1.1e-03	NA	1.1e-06	NA	7.5e-07
8	GTEx	Lung	0.1430	0.0482	9.7e-04	0.052	NA	0.015	NA	0.024	8.1e-05	NA	2.2e-02	NA	5.7e-03
9	GTEx	Muscle Skeletal	0.0947	0.0298	2.2e-05	0.097	NA	0.090	NA	0.093	8.9e-10	NA	4.0e-09	NA	2.0e-09
10	GTEx	Thyroid	0.1170	0.0380	6.8e-05	-0.002	NA	0.020	NA	0.015	4.5e-01	NA	1.1e-02	NA	2.5e-02
11	ROSMAP	Brain Pre-frontal Cortex	0.1038	0.0301	1.0e-07	0.082	0.068	0.078	0.071	0.068	9.5e-11	4.3e-09	3.0e-10	2.0e-09	3.7e-09
12	TCGA	Kidney Renal Clear Cell Carcinoma	0.0329	0.0187	7.6e-03	0.025	0.014	0.014	NA	0.019	7.8e-04	9.7e-03	8.6e-03	NA	3.1e-03
13	TCGA	Prostate Adenocarcinoma	0.0322	0.0175	3.5e-03	0.006	0.017	0.009	NA	0.008	7.6e-02	5.5e-03	3.9e-02	NA	4.1e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Shortness of breath walking on level ground	8.5	10.1	15.8	-3.7	-0.9	-3.9	-3.5	-3.8	-4.0	-3.6	-2.4	-3.8	-3.8	-1.7	0.3	-3.0
Seen a psychiatrist for nerves, anxiety, tension or depression	7.8	10.1	26.5	-2.8	-0.2	-1.1	-1.8	-3.2	-4.2	-5.2	-2.3	-4.3	-4.0	-3.2	-0.6	-3.8
Type 2 Diabetes (T2D) (2018)	5.6	10.4	15.7	-3.2	-2.9	-3.4	-3.1	-3.4	-3.6	-3.3	-3.0	-3.3	-3.8	-2.6	-2.1	-4.0
Wheeze or whistling in the chest in last year	5.4	9.7	17.0	-2.9	-2.0	-4.0	-4.1	-3.3	-3.4	-3.5	-3.2	-3.7	-3.6	-1.6	1.6	-2.3
Frequency of unenthusiasm / disinterest in last 2 weeks	5.1	6.9	14.1	-3.2	0.2	-3.3	-3.3	-3.8	-2.4	-3.2	-1.3	-2.3	-2.2	-3.0	-0.0	-2.5
Respiratory disease	4.5	10.0	22.7	-2.3	-2.3	-2.7	-2.4	-3.6	-3.9	-4.8	-2.8	-3.8	-3.9	-3.3	0.9	-2.5
Diabetes (mother)	4.5	5.7	14.3	-3.4	0.6	-3.6	-3.8	-3.8	-1.2	-2.7	0.7	-0.7	-0.9	-2.5	-1.7	-1.2
Current tobacco smoking	4.4	7.2	12.7	-2.4	-1.1	-3.6	-2.9	-3.1	-2.8	-2.6	-2.1	-2.8	-3.2	-3.1	-1.1	-2.9
Townsend deprivation index at recruitment	4.2	5.9	12.9	-2.2	-1.0	-3.1	-3.2	-2.9	-2.3	-3.6	-2.0	-2.7	-1.9	-2.4	0.6	-1.6
Illnesses of siblings: Diabetes	4.0	4.9	7.3	-2.3	-1.4	-2.7	-2.2	-2.6	-1.8	-2.2	-2.4	-1.4	-2.7	-2.6	-0.6	-2.7
Major Depression (MDD)	3.9	4.7	9.3	-2.4	-1.3	-1.7	-1.9	-2.7	-2.1	-2.2	-1.1	-1.6	-2.8	-2.9	-1.0	-3.1
Medication: Metformin	3.9	5.5	12.4	-2.3	-1.1	-3.5	-3.2	-3.1	-1.8	-2.7	-2.1	-1.3	-2.5	-2.6	0.0	-1.8
Birth weight of first child	3.9	7.0	10.7	3.3	1.7	2.7	3.0	2.9	3.0	3.3	1.9	2.9	2.9	1.9	1.1	2.8
Back pain experienced in last month	3.8	5.6	12.4	-2.3	0.3	-1.9	-2.1	-2.9	-2.8	-3.5	-1.9	-3.2	-2.6	-1.7	-0.7	-2.4
Fasting Glucose	3.6	4.4	11.8	-1.5	-2.6	-1.4	-0.8	-0.6	-2.1	-1.5	-3.1	-1.5	-3.3	-1.8	0.7	-3.4
Long-standing illness, disability or infirmity	3.6	5.5	12.0	-2.2	0.2	-2.6	-2.6	-2.4	-3.1	-3.5	-1.3	-3.0	-2.1	-1.3	-0.0	-2.9
Tinnitus: Yes, now most or all of the time	3.5	4.1	8.0	-2.4	2.1	-1.9	-2.1	-2.6	-2.3	-2.8	0.1	-1.6	-1.3	-2.5	-1.0	-1.9
Neuroticism (2016)	3.4	4.9	12.8	-1.5	-0.2	-3.0	-3.6	-1.8	-1.9	-2.6	-2.7	-2.1	-2.2	-1.4	1.3	-2.2
Type 2 Diabetes (T2D) (2012)	3.3	3.8	7.2	-2.3	-1.0	-1.2	-1.5	-2.4	-2.2	-1.7	-1.4	-1.9	-2.5	-2.7	-0.6	-2.5
Severe depression (siblings)	3.3	3.7	8.7	-1.7	-1.9	-0.6	-1.0	-1.8	-2.3	-2.9	-2.4	-2.6	-2.3	-1.2	0.3	-1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	3.2	4.9	11.6	-1.9	0.8	-0.4	-0.7	-2.7	-3.0	-3.4	-1.2	-3.0	-2.5	-2.6	0.1	-2.8
Depression (self-reported)	3.1	3.7	7.8	-2.8	-0.7	-1.7	-1.3	-2.7	-1.8	-2.8	-1.4	-2.0	-2.1	-1.8	0.5	-1.8
Smoking status: Current	3.1	4.9	10.7	-2.0	-0.9	-3.3	-2.7	-2.5	-2.2	-1.8	-1.3	-2.1	-2.3	-2.6	-1.7	-2.4
Frequency of depressed mood in last 2 weeks	3.0	4.2	7.7	-2.2	-0.3	-2.1	-2.0	-2.4	-2.0	-2.8	-2.0	-2.0	-2.6	-1.9	1.0	-1.9
Diabetes diagnosed by doctor	3.0	5.0	11.0	-1.9	-2.3	-3.3	-2.4	-2.3	-2.1	-1.8	-2.1	-1.6	-2.5	-2.1	-1.0	-2.7
Lung FVC	2.9	14.5	35.4	5.5	0.7	4.0	3.5	5.9	3.5	3.9	2.1	3.1	3.5	5.4	-0.0	3.5
Exposure to tobacco smoke outside home	2.8	3.7	8.5	2.1	0.4	1.3	1.2	2.3	2.1	2.2	0.5	1.8	2.4	2.4	1.4	2.9
Ever taken oral contraceptive pill	2.8	3.2	7.6	-2.3	-1.2	-0.6	-2.1	-2.4	-1.8	-2.0	-1.2	-1.7	-1.7	-2.8	-0.6	-1.3
Peak expiratory flow (PEF)	2.7	6.2	13.5	3.6	0.6	2.8	1.9	3.7	2.1	3.0	2.0	2.7	2.2	2.8	-1.3	1.8
Average weekly beer plus cider intake	2.7	3.9	8.3	-0.7	-1.5	-2.2	-2.6	-1.3	-2.9	-1.5	-1.5	-2.3	-2.6	-1.0	-1.4	-2.4
Depression (Nagel 2018)	2.6	4.0	9.7	-2.3	0.1	-2.1	-2.1	-3.1	-1.6	-3.0	-1.1	-1.7	-2.0	-2.3	1.0	-1.5
Schizophrenia vs Biploar Disorder	2.6	3.4	7.9	1.6	0.8	2.0	2.5	2.0	1.8	2.1	0.5	1.6	1.5	2.8	1.9	1.8
Alcohol usually taken with meals	2.6	4.2	7.3	2.3	1.6	1.7	1.7	2.4	1.8	2.6	2.5	2.2	2.7	2.2	-0.7	1.2
Asthma (self-reported)	2.6	5.2	12.2	-1.9	-1.0	-3.5	-3.1	-2.8	-2.4	-2.7	-1.5	-2.3	-2.4	-1.7	1.4	-1.3
Hearing aid user	2.6	2.9	7.6	-1.0	-0.6	0.1	0.3	-0.8	-2.3	-2.8	-2.6	-2.7	-2.3	-0.6	1.6	-1.2
Medication: Paracetamol	2.6	4.0	8.4	-2.8	-0.6	-2.9	-1.9	-2.9	-1.7	-2.5	-1.1	-1.6	-2.2	-1.6	-0.5	-2.0
Hair/balding pattern: Pattern 3	2.5	3.7	9.8	3.1	-0.2	2.1	2.0	3.1	1.8	2.5	-0.1	1.3	1.0	1.1	2.0	1.6
Pulse wave Arterial Stiffness index	2.5	3.0	9.6	-0.7	-2.9	-1.3	-1.7	-0.9	-1.4	-1.1	-3.1	-1.7	-2.3	-0.7	0.4	-1.6
Overall health rating	2.5	5.4	13.3	-3.6	-0.5	-3.1	-2.5	-3.6	-1.7	-2.0	-1.8	-1.6	-2.1	-2.5	0.9	-1.8
Asthma	2.4	4.8	11.1	-1.7	-1.0	-3.3	-2.9	-2.6	-2.4	-2.8	-1.5	-2.4	-2.3	-1.4	1.3	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.4	5.1	8.6	2.1	1.4	2.4	1.3	2.8	2.9	2.5	2.1	2.9	2.3	2.4	-0.7	2.3
Average weekly spirits intake	2.3	2.8	4.2	-1.9	-1.5	-2.1	-1.4	-1.8	-1.9	-1.6	-0.9	-1.5	-1.3	-1.8	-1.6	-2.0
Medication for hormone replacement therapy	2.3	2.6	6.9	-0.7	0.3	-0.4	-1.3	-1.2	-2.3	-2.6	-1.9	-2.2	-1.7	-1.5	1.2	-1.4
Leg pain on walking	2.3	2.9	7.4	-2.3	0.3	-1.9	-1.7	-2.7	-1.2	-2.0	-1.4	-1.1	-2.2	-1.4	1.0	-1.4
Miserableness	2.3	3.9	8.4	-1.9	-0.4	-1.5	-1.8	-2.1	-2.2	-2.7	-2.1	-2.0	-2.2	-1.7	0.1	-2.9
Alcohol drinker status: Previous	2.3	2.6	6.8	-1.5	-1.9	-1.0	-0.1	-1.4	-1.4	-1.4	-2.2	-1.4	-2.6	-1.7	0.3	-2.0
Eye problems/disorders: Diabetes related eye disease	2.2	2.4	6.0	-1.9	-1.1	-1.6	-2.0	-1.1	-1.5	-1.4	-0.8	-0.3	-2.0	-0.5	-1.8	-2.4
Vitamin and mineral supplements	2.2	3.0	7.0	2.1	1.0	1.9	1.4	2.2	0.8	1.5	2.5	1.0	2.0	2.6	-1.2	0.7
Pulse wave peak to peak time	2.2	2.6	9.1	0.6	2.7	1.3	1.7	0.9	1.1	1.0	3.0	1.5	2.1	0.4	-0.7	1.4
Mouth/teeth dental problems: Mouth ulcers	2.2	3.4	11.2	3.3	0.4	1.9	2.8	3.1	0.1	1.8	-1.1	0.3	-0.4	2.4	1.4	0.1
Had major operations	2.1	2.4	9.0	-0.3	-0.8	-0.6	-0.6	-1.1	-2.1	-2.0	-1.6	-1.5	-1.9	-0.9	-1.6	-3.0
Arm fat percentage (left)	2.1	8.3	25.5	-2.7	-1.5	-5.0	-4.6	-3.6	-2.3	-3.8	-1.6	-2.2	-2.1	-2.2	-0.5	-1.3
Breast cancer (self-reported)	2.1	2.5	8.5	0.2	0.9	-1.0	-0.9	0.9	2.2	2.5	1.1	2.9	1.7	0.4	1.7	1.4
Bipolar Disorder (2011)	2.0	1.9	6.0	0.2	-2.1	1.6	1.4	0.5	-1.3	-1.1	-2.5	-1.6	-1.3	-0.4	0.3	-1.4
Primary Biliary Cirrhosis	2.0	2.9	11.1	-1.4	-2.7	-1.9	-0.8	-1.8	0.4	-1.2	-2.3	-0.2	-0.8	-1.2	3.3	-0.0
Trunk fat percentage	2.0	8.0	28.2	-2.4	-1.1	-5.3	-4.8	-3.6	-2.2	-3.1	-1.1	-2.1	-1.5	-2.4	-1.4	-1.4
Relative age voice broke	2.0	3.1	8.5	-1.4	-1.8	-2.9	-2.8	-1.8	-1.7	-1.3	-0.7	-1.6	-1.2	-1.6	-1.2	-1.6
Arm fat percentage (right)	2.0	7.8	22.9	-2.5	-1.4	-4.8	-4.5	-3.5	-2.2	-3.7	-1.7	-2.1	-2.2	-2.4	-0.4	-1.2
HDL Cholesterol	1.9	3.2	7.3	2.5	1.2	1.6	1.1	2.7	1.6	2.2	1.2	1.5	2.3	1.7	0.0	2.0
Trunk fat mass	1.9	8.3	26.2	-2.8	-1.2	-5.1	-4.5	-3.8	-2.3	-3.1	-0.9	-2.1	-1.6	-2.8	-2.1	-1.6
Illnesses of siblings	1.9	2.7	8.9	1.9	1.3	3.0	2.5	2.1	0.6	1.8	1.2	0.4	1.2	1.3	-0.1	1.6
Frequency of tiredness / lethargy in last 2 weeks	1.9	3.0	5.3	-1.5	0.5	-1.4	-1.1	-1.7	-2.0	-2.2	-2.3	-2.2	-2.0	-0.6	1.4	-2.3
Medication: Ibuprofen (e.g. Nurofen)	1.9	2.4	6.2	-1.5	-1.5	-1.1	-0.4	-1.9	-0.6	-0.7	-1.6	-0.8	-2.5	-2.5	-0.1	-2.2
Family relationship satisfaction	1.9	2.4	5.1	-2.1	0.9	-1.0	-2.2	-1.8	-1.5	-1.6	-0.8	-1.1	-1.8	-1.7	-1.0	-1.7
Ever depressed for a whole week	1.9	2.4	4.8	-2.0	-0.3	-0.8	-1.3	-2.0	-2.0	-2.2	-0.4	-1.6	-1.8	-0.9	-1.1	-2.1
Medication: Paracetamol	1.8	3.0	5.9	-2.1	-0.4	-2.1	-1.5	-2.4	-1.6	-2.3	-1.2	-1.6	-1.9	-1.5	-0.2	-1.9
Body fat percentage	1.8	7.1	24.6	-2.5	-1.1	-5.0	-4.4	-3.4	-1.9	-3.3	-1.4	-1.9	-1.8	-2.0	-0.5	-1.2
Health satisfaction	1.8	2.3	5.9	-2.4	-0.2	-2.3	-1.9	-2.2	-1.2	-1.4	-0.8	-0.8	-1.7	-1.2	-0.1	-1.2
Arm fat mass (left)	1.8	7.3	22.9	-2.8	-1.2	-4.8	-4.1	-3.6	-2.0	-3.3	-0.8	-1.8	-1.6	-2.7	-1.6	-1.3
Multivitamins +/- minerals	1.7	2.1	5.9	-1.8	-1.1	-2.4	-2.1	-1.7	-1.0	-1.0	-1.7	-0.7	-1.1	-1.8	-0.3	-0.7
Ever unenthusiastic/disinterested for a whole week	1.7	2.1	4.2	-1.7	-0.0	-0.5	-1.1	-1.8	-1.8	-2.0	-0.7	-1.6	-1.7	-0.3	-1.4	-1.9
Arm fat mass (right)	1.7	6.9	20.2	-2.5	-1.1	-4.5	-3.9	-3.4	-2.2	-3.3	-1.0	-2.0	-1.7	-2.7	-1.6	-1.3
Ever highly irritable/argumentative for 2 days	1.7	2.0	4.7	-1.4	-0.4	0.1	-0.4	-1.5	-2.0	-2.2	-0.8	-2.2	-1.5	-0.9	-1.5	-1.3
Neck or shoulder pain in last month	1.7	2.3	7.4	-0.0	-0.3	-0.4	-0.1	0.1	-2.1	-2.3	-2.4	-2.7	-1.9	0.4	1.2	-1.4
Whole body fat mass	1.7	7.0	22.7	-2.7	-1.4	-4.8	-3.9	-3.6	-1.9	-3.1	-1.0	-1.9	-1.6	-2.6	-1.4	-1.4
Leg fat mass (right)	1.7	6.5	18.7	-2.8	-1.4	-4.3	-3.5	-3.4	-1.8	-3.3	-1.4	-1.9	-1.8	-2.3	-0.9	-1.5
Irritability	1.7	2.9	5.6	-2.1	-1.0	-1.9	-1.9	-1.6	-2.0	-2.4	-1.2	-1.7	-1.8	-0.9	-0.4	-2.1
Pain experienced in last month	1.7	2.9	5.8	1.2	0.3	1.4	1.4	1.2	2.1	2.2	2.4	2.3	2.4	0.5	-1.0	1.7
Smoking Status	1.6	3.8	8.4	-2.3	-1.6	-2.9	-2.5	-2.6	-1.3	-1.2	-0.5	-0.6	-1.4	-2.5	-2.0	-2.1
Number of treatments/medications taken	1.6	3.0	5.5	-1.9	-0.5	-2.1	-1.8	-2.3	-1.2	-2.3	-2.0	-1.6	-1.6	-1.9	0.8	-1.3
Other serious medical condition/disability diagnosed by doctor	1.6	2.1	5.2	-1.8	0.7	-1.4	-0.8	-2.0	-1.6	-2.3	-1.1	-1.8	-1.0	-0.7	1.8	-0.4
Age when periods started (menarche)	1.6	3.8	9.7	1.4	-1.3	1.7	2.0	1.2	2.7	3.1	1.4	2.9	2.4	0.6	-0.1	1.9
Allergy	1.6	3.7	7.7	0.8	-0.9	2.3	2.1	2.1	2.8	2.6	0.4	2.4	2.1	1.6	0.7	2.2
Diabetes (self-reported)	1.6	2.4	6.5	-1.4	-1.2	-2.6	-1.3	-1.9	-1.4	-1.3	-1.3	-0.7	-1.5	-1.8	-0.8	-1.9
Blood clot in the leg (DVT)	1.6	2.1	4.7	-1.0	0.7	-1.6	-0.8	-1.1	-1.6	-1.7	-1.8	-1.9	-2.2	-0.2	0.3	-2.0
Chronic bronchitis/emphysema (mother)	1.6	1.9	5.7	-1.0	0.4	-1.1	-1.0	-1.0	-2.0	-2.1	-1.6	-2.4	-1.3	-0.3	0.5	-1.0
Commuting to job workplace: Car/motor vehicle	1.6	1.8	3.9	1.3	2.0	1.6	1.5	1.3	1.7	1.1	0.9	1.0	0.8	0.9	1.2	1.7
Alcohol drinker status: Never	1.6	1.9	4.2	1.0	0.4	1.4	1.2	1.3	2.1	0.8	1.6	1.5	1.8	1.6	0.4	1.5
Mean Putamen Volume	1.5	1.7	4.4	-0.8	-2.0	-0.3	-0.4	-1.5	-1.3	-1.2	-1.7	-0.9	-1.4	-2.1	-0.3	-1.4
LDL Cholesterol	1.5	2.3	6.3	1.7	-0.2	1.8	1.7	2.0	1.2	0.8	-0.5	0.2	0.8	1.9	2.5	2.1
Pack years adult smoking proportion	1.5	2.2	5.1	-1.1	-1.0	-1.1	-1.3	-1.8	-1.5	-2.2	-1.2	-2.1	-1.7	-1.6	-0.4	-1.2
Fed-up feelings	1.5	2.7	7.4	-1.3	0.9	-1.0	-0.9	-1.5	-2.1	-2.5	-0.9	-2.2	-1.9	-0.7	-0.3	-2.7
Weight	1.5	7.2	19.1	-2.9	-1.1	-4.4	-3.4	-3.6	-2.0	-3.1	-0.6	-1.8	-1.6	-3.2	-2.6	-1.9
Alcohol intake versus 10 years previously	1.5	2.3	7.0	1.0	-0.8	-0.2	-1.4	0.8	-2.1	-1.4	-2.3	-2.6	-1.6	0.8	0.2	-1.7
Migraine (self-reported)	1.5	1.8	4.5	2.0	0.8	2.1	1.7	2.0	0.7	0.9	0.6	0.6	1.1	2.0	0.1	0.3
Pain type(s) experienced in last month: Hip pain	1.5	1.9	7.3	0.0	-1.1	-0.3	0.3	-0.3	-1.6	-2.7	-1.6	-2.5	-1.5	-0.1	0.6	-1.2
Deep venous thrombosis (DVT) (self-reported)	1.5	1.9	4.5	-1.0	0.6	-1.6	-0.9	-0.9	-1.6	-1.6	-1.8	-1.7	-2.1	-0.1	0.0	-1.8
Blood White Count	1.4	10.6	20.9	-4.3	-1.9	-3.1	-3.7	-4.6	-2.4	-4.0	-1.0	-2.1	-2.9	-4.4	-2.7	-3.0
Ever used hormone-replacement therapy (HRT)	1.4	1.8	3.7	-1.1	-0.8	-1.1	-0.6	-1.8	-1.9	-1.6	-1.9	-1.7	-1.2	-1.3	0.7	-0.4
Taking other prescription medications	1.4	2.2	6.3	-1.4	-0.4	-2.0	-1.6	-2.4	-1.2	-2.5	-0.8	-1.4	-0.7	-1.3	0.3	-1.2
Forced expiratory volume in 1-second (FEV1)	1.4	4.9	7.8	2.3	0.9	1.7	1.1	2.8	2.2	2.7	2.7	2.5	2.7	1.9	-2.4	1.6
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	5.1	-1.7	-0.2	-0.2	-0.7	-2.3	1.5	0.1	1.6	1.5	0.8	-0.4	0.8	1.5
Wears glasses or contact lenses	1.4	1.6	5.0	1.8	-0.7	1.6	2.2	2.2	0.1	0.8	-0.6	0.3	0.4	1.9	0.0	-0.5
Pack years of smoking	1.4	2.1	5.8	-0.9	-0.8	-1.0	-1.2	-1.7	-1.7	-2.3	-1.2	-2.4	-1.5	-1.3	-0.3	-1.0
Depressed Affect (Nagel 2018)	1.3	2.6	7.5	-0.8	-0.0	-0.6	-0.5	-1.2	-2.2	-2.0	-2.0	-2.5	-2.2	-0.4	0.5	-2.7
Schizophrenia (2018)	1.3	2.6	5.1	1.8	1.7	2.2	1.8	1.4	0.9	1.5	1.0	0.7	1.7	2.3	1.8	1.5
Coronary Artery Disease (CAD)	1.3	1.5	3.7	0.4	-0.0	1.4	0.9	0.9	1.9	1.4	1.1	1.4	1.7	0.8	0.6	1.8
Supplements: Zinc	1.3	1.5	3.5	-1.2	-0.6	-1.5	-0.6	-1.4	-1.5	-1.9	-0.3	-1.5	-0.9	-1.5	-0.5	-1.2
Leg predicted mass (left)	1.3	6.7	15.2	-3.0	-0.8	-3.5	-2.8	-3.4	-1.9	-2.5	-0.0	-1.4	-1.3	-3.4	-3.9	-2.2
Waist circumference	1.3	4.6	20.7	-2.6	-1.6	-4.5	-3.2	-2.8	-0.9	-1.9	-0.8	-0.8	-1.1	-2.1	-0.7	-0.4
Leg fat percentage (right)	1.3	4.9	13.0	-2.2	-1.1	-3.6	-2.8	-2.8	-1.7	-3.4	-1.9	-1.9	-1.9	-1.4	0.4	-1.2
Medication: Ibuprofen	1.3	1.6	4.7	-0.7	-1.2	-1.2	-0.6	-1.3	-0.4	0.1	-1.4	-0.5	-2.2	-1.9	-0.2	-2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.6	4.5	1.8	-1.3	2.0	1.3	2.1	-0.1	0.6	-0.9	-0.5	0.3	1.5	0.3	1.2
Number of self-reported non-cancer illnesses	1.3	2.3	5.3	-1.4	-1.5	-2.2	-1.5	-1.7	-1.1	-2.3	-1.4	-1.2	-0.9	-0.2	1.9	-0.7
Ever had prostate specific antigen (PSA) test	1.3	1.5	6.0	-1.6	0.3	-2.4	-1.8	-1.9	-0.0	-1.1	-0.0	0.2	-0.1	-1.4	-0.6	-0.2
Leg fat mass (left)	1.3	5.0	16.1	-2.5	-1.2	-4.0	-3.0	-3.1	-1.4	-3.0	-1.1	-1.5	-1.6	-2.0	-0.8	-1.2
Heel T-Score	1.2	9.5	19.0	-3.7	-1.5	-2.1	-2.0	-4.1	-2.3	-4.4	-2.0	-2.0	-4.0	-4.3	-0.0	-3.8
Leg fat-free mass (left)	1.2	6.3	14.6	-2.8	-0.8	-3.4	-2.7	-3.3	-1.8	-2.4	-0.1	-1.4	-1.2	-3.3	-3.8	-2.2
Forced vital capacity (FVC)	1.2	4.7	9.5	2.4	0.9	1.0	0.8	2.4	1.9	2.8	3.1	2.2	2.6	1.7	-3.1	1.3
Pulse rate	1.2	2.1	10.6	-1.8	-1.2	-2.4	-3.3	-2.1	0.3	-0.1	0.2	0.3	0.0	-1.2	-0.2	0.0
Mouth/teeth dental problems: Dentures	1.2	2.0	4.6	-0.5	-0.3	-2.0	-1.9	-1.5	-1.9	-2.1	-0.9	-1.6	-1.4	-0.2	-1.1	-0.6
Lung cancer (father)	1.2	1.4	4.3	-0.3	-0.3	-0.9	-0.9	-0.0	-1.7	-2.1	-1.3	-2.1	-1.1	0.2	1.3	-0.5
Length of working week for main job	1.2	1.4	5.4	0.3	-1.1	-1.1	-1.6	0.5	-1.2	-0.3	-0.9	-0.8	-1.4	0.8	-1.3	-2.3
Qualifications: O levels/GCSEs or equivalent	1.2	1.9	5.4	0.9	-1.1	1.4	2.0	1.3	1.7	2.3	-0.1	1.9	0.8	0.3	1.0	0.9
Medication for pain relief, constipation, heartburn	1.2	2.0	4.7	1.5	0.7	1.2	1.7	2.2	1.0	1.4	1.2	1.3	1.4	2.1	0.4	1.2
Osteoarthritis (self-reported)	1.2	1.5	5.9	1.1	0.4	1.3	1.1	1.0	0.9	0.1	0.3	-0.0	1.1	2.4	1.8	1.9
Unable to work because of sickness or disability	1.2	1.5	4.0	-1.4	0.2	-1.6	-1.3	-0.6	-1.3	-1.4	-1.1	-1.1	-1.6	0.4	-0.1	-2.0
Alzheimer’s Disease (in father)	1.1	1.2	4.0	-0.4	-0.4	1.5	2.0	-0.3	-0.3	-0.7	-1.6	-0.5	-1.8	-0.5	0.9	-1.0
Lupus	1.1	1.6	10.0	0.6	0.4	1.9	1.4	0.0	0.8	1.1	-1.3	0.6	-0.2	-0.5	3.2	1.1
Schizophrenia (2014)	1.1	2.3	6.3	1.6	1.3	1.7	1.3	1.1	0.8	1.3	0.4	0.8	1.6	2.0	2.5	1.9
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.6	7.3	-1.4	-0.5	0.2	-0.8	-2.0	-1.4	-2.1	0.2	-1.1	-1.9	-2.7	-1.9	-2.0
Serious illness, injury or assault to yourself	1.1	1.3	4.5	-0.8	1.4	-0.0	-0.6	-0.7	0.9	1.3	2.1	1.4	1.3	0.4	-0.6	1.5
Sitting height	1.1	8.1	31.9	-2.8	-0.8	-1.5	-1.5	-3.3	-2.4	-1.4	0.1	-1.7	-1.9	-4.2	-5.7	-4.2
Had menopause	1.1	1.4	3.0	0.8	1.0	0.2	0.9	0.6	1.6	1.4	0.4	1.4	1.4	1.1	1.4	1.7
Hip circumference	1.1	4.8	13.4	-2.4	-0.9	-3.7	-2.6	-3.2	-1.3	-2.6	-0.5	-1.3	-1.3	-2.7	-2.1	-1.4
Worrier / anxious feelings	1.1	2.1	5.3	2.2	1.0	1.8	1.4	1.8	1.4	1.6	-0.2	1.2	0.4	1.0	2.3	1.0
Medication: Cholesterol lowering	1.1	1.6	5.6	-1.4	-1.4	-1.3	-2.4	-1.5	-0.7	-2.1	-0.2	-0.7	-0.1	-0.5	-1.1	-0.8
Chest pain or discomfort	1.1	1.6	4.5	-1.2	-1.0	-1.4	-1.5	-0.7	-1.7	-0.7	-1.0	-2.1	-1.6	0.2	0.0	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.4	7.8	-2.0	0.9	-0.5	-0.8	-2.3	-1.3	-1.1	0.9	-0.5	-0.3	-2.8	-2.4	-1.4
Myopia	1.1	1.6	3.0	1.6	1.7	-0.5	-0.6	1.2	1.2	1.7	1.0	0.9	1.7	1.6	0.7	0.7
Alzheimer’s Disease (in mother)	1.0	1.1	4.5	-1.2	-1.2	-2.1	-1.7	-1.2	-0.7	-0.1	-0.2	0.0	-0.5	-0.2	-1.3	-0.5
Ulcerative Colitis	1.0	1.4	4.4	-1.7	-2.1	-0.6	-0.9	-1.4	-0.8	-1.7	-0.8	-1.6	-0.9	-0.5	0.3	-0.4
Ever had hysterectomy (womb removed)	1.0	1.1	3.1	-1.1	-0.6	-0.7	-0.5	-1.3	-0.7	-1.6	-0.8	-0.7	-1.1	-1.8	1.1	-0.1
Body mass index (BMI)	1.0	4.1	13.2	-2.1	-1.2	-3.6	-2.9	-2.5	-1.3	-3.0	-1.1	-1.3	-1.6	-1.4	-0.5	-0.8
Financial difficulties in last 2 years	1.0	1.4	2.6	-0.4	0.5	-1.4	-1.0	-1.2	-1.0	-1.6	-1.4	-1.5	-1.0	-0.8	1.6	-1.1
Pain all over the body in last month	1.0	1.1	6.5	-1.5	-0.1	-2.6	-1.7	-1.0	-0.1	-0.2	0.2	-0.2	-0.3	0.4	0.5	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.1	9.8	2.0	0.8	1.9	1.0	2.3	1.1	1.5	2.0	1.4	1.8	1.5	-3.1	0.8
Number of full brothers	1.0	1.2	3.9	0.1	-0.0	-0.1	-0.4	-0.6	1.8	0.9	1.3	1.4	1.8	-0.4	0.5	2.0
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.1	5.5	0.6	0.6	-0.1	-0.8	0.6	1.4	1.2	-0.4	1.5	1.0	0.1	2.3	0.9
Number of full sisters	1.0	1.2	3.0	1.0	0.5	-1.3	-0.7	1.2	1.7	1.0	-0.1	1.2	1.4	1.0	1.1	1.2
Leg fat-free mass (right)	1.0	5.1	16.2	-2.5	-0.4	-2.9	-2.2	-2.9	-1.5	-2.1	0.4	-1.1	-0.9	-3.1	-4.0	-1.9
Loneliness, isolation	1.0	1.4	4.6	-0.7	-0.1	-0.5	-0.1	-0.7	-1.7	-1.8	-1.2	-2.1	-1.5	0.1	0.7	-1.2
Commuting to job workplace: Walk	1.0	1.1	2.9	0.8	-0.0	-1.7	-1.7	0.1	-1.4	-0.9	-0.9	-1.1	-1.3	-0.0	0.4	-1.2
Medication for cholesterol	1.0	1.5	3.4	-1.6	0.3	-0.6	-0.8	-1.2	1.3	1.6	1.8	1.8	0.4	0.2	-1.6	0.6
Financial situation satisfaction	1.0	1.2	2.4	-1.2	1.1	-1.5	-1.1	-1.5	-0.7	-0.7	-0.8	-0.7	-1.4	0.0	1.1	-1.3
Supplements: Calcium	1.0	1.1	3.7	-1.9	0.2	-1.1	0.1	-1.7	0.4	1.2	0.0	0.8	0.1	-1.9	0.1	-0.1
Alzheimer’s Disease (including proxy)	0.9	1.3	4.0	-1.9	-1.0	-1.4	-0.5	-2.0	-0.9	-0.7	-0.7	-0.1	-1.4	-0.9	-0.7	-1.3
Ovarian Cancer	0.9	1.2	4.8	0.0	0.3	-0.6	-0.4	-0.6	1.2	0.4	2.1	1.2	1.6	0.1	-0.5	2.2
BMI	0.9	5.2	13.9	-2.5	-1.5	-3.3	-3.2	-2.5	-1.8	-3.7	-0.8	-1.8	-2.0	-2.0	-1.2	-1.1
Medication: Co-codamol	0.9	1.1	4.6	-1.6	0.7	-0.2	-0.1	-1.3	-0.7	-2.2	-0.7	-1.2	-1.2	0.3	-0.5	-0.8
Mouth/teeth dental problems	0.9	1.5	4.9	-0.5	0.2	1.1	0.5	0.0	1.5	1.0	2.0	1.6	2.2	-0.5	-0.7	1.1
Neuroticism score	0.9	1.9	4.5	-0.7	0.5	-0.3	-1.0	-1.0	-1.9	-2.1	-1.4	-1.9	-1.9	-0.3	0.6	-2.1
Breastfed as a baby	0.9	1.1	3.0	1.1	-1.1	1.3	1.7	1.0	0.5	1.1	0.1	1.0	1.0	-0.1	1.1	1.2
Pulse wave reflection index	0.9	1.1	3.6	1.9	0.3	1.6	1.3	1.6	0.7	0.6	-0.5	0.2	0.3	1.4	-0.0	0.6
Gout (self-reported)	0.9	1.3	2.6	-1.2	-0.9	-0.8	-0.4	-1.1	1.5	1.2	0.5	1.6	1.0	-1.5	0.6	1.5
Medication: Allopurinol	0.9	1.1	2.4	-1.1	-0.8	-0.0	0.4	-1.3	1.5	1.2	0.3	1.6	0.7	-1.4	0.9	1.4
Comparative height size at age 10	0.9	5.0	23.0	-2.1	1.1	-1.3	-1.4	-3.1	-1.7	-1.0	1.1	-1.0	-0.6	-3.5	-4.8	-2.2
Leg predicted mass (right)	0.9	5.0	15.1	-2.5	-0.4	-2.8	-2.2	-2.9	-1.5	-2.1	0.3	-1.1	-0.9	-3.1	-3.9	-1.9
Basal metabolic rate	0.9	4.9	13.0	-2.6	-0.7	-3.0	-2.1	-3.1	-1.3	-1.9	0.2	-1.0	-0.9	-3.2	-3.6	-1.8
Leg fat percentage (left)	0.9	3.2	9.7	-1.8	-0.9	-3.1	-2.2	-2.3	-1.2	-2.9	-1.6	-1.4	-1.5	-1.1	0.5	-0.9
Basal cell carcinoma (self-reported)	0.9	1.1	3.2	0.3	0.2	-0.0	0.5	1.3	1.2	1.8	0.7	1.4	1.2	0.5	1.2	1.3
Verbal and Numeric Reasoning (VNR)	0.8	1.9	6.5	2.0	-0.5	2.5	1.7	1.9	0.9	1.4	0.4	0.6	0.3	1.9	0.3	0.4
Rheumatoid Arthritis	0.8	1.1	2.7	1.4	0.0	-0.3	-0.1	1.6	-1.5	-0.8	-1.3	-1.3	-1.1	0.7	-0.5	-1.4
Allergy or Eczema	0.8	2.1	5.6	-0.5	1.4	-2.4	-1.8	-1.7	-1.4	-2.2	-0.2	-1.4	-0.8	-1.3	-0.5	-1.4
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	2.9	0.7	-0.8	1.4	0.5	0.7	-1.1	-0.2	-0.2	-1.3	-0.1	1.4	-1.7	-0.4
Had other major operations	0.8	0.9	4.1	0.0	1.1	0.8	0.9	0.0	1.1	0.6	-0.2	1.0	0.3	0.1	2.0	1.5
Noisy workplace	0.8	1.0	4.2	-0.6	-0.5	-1.5	-2.1	-0.8	-1.0	-1.4	-0.1	-1.0	-0.5	-0.2	-0.9	-0.3
Prospective memory result	0.8	0.9	3.4	0.5	0.0	1.3	1.8	1.1	0.8	0.6	0.6	0.9	0.9	0.9	0.4	1.4
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	3.1	1.8	1.7	1.4	1.6	1.1	0.7	1.8	0.6	0.8	0.3	1.0	0.7	0.6
Medication: Ventolin 100micrograms inhaler	0.8	1.0	3.0	-0.8	1.5	-1.4	-1.6	-1.7	-0.3	-0.7	0.5	-0.1	-0.3	-1.1	-0.0	-0.5
Worry too long after embarrassment	0.8	1.4	4.2	-0.7	0.8	-0.6	-1.8	-0.6	-1.3	-0.9	-0.1	-1.1	-1.5	-0.8	-1.4	-2.1
Heart disease (mother)	0.8	1.0	4.5	0.6	-0.0	0.2	0.7	1.5	0.4	0.5	-0.6	0.4	0.4	1.8	2.1	0.7
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	7.1	-0.7	-2.7	0.8	1.2	-0.1	0.7	0.1	-0.2	0.6	-0.4	-1.2	-0.7	-0.7
Supplements: Vitamin C	0.8	0.9	2.6	0.6	1.5	1.1	1.3	0.6	1.0	0.5	-0.6	1.1	-0.3	-0.6	1.6	0.1
Guilty feelings	0.8	1.3	3.0	-1.3	0.5	-1.2	-1.4	-1.3	-1.3	-1.7	-0.7	-1.3	-1.2	-0.3	0.0	-1.0
Medication: Lisinopril	0.8	1.0	3.5	-0.8	-1.1	-0.3	0.0	-0.9	-1.2	-1.2	-0.8	-1.1	-0.9	-1.9	0.5	-1.1
Fractured/broken bones in last 5 years	0.8	1.1	3.3	-1.6	-0.9	-1.4	-1.2	-1.8	0.2	0.2	0.2	0.5	-0.7	-1.5	0.9	0.1
Cholesterol lowering medication	0.8	1.2	3.5	1.8	0.4	1.2	1.9	1.5	-0.3	-0.0	-0.5	-0.8	0.7	1.1	1.3	0.8
Bipolar Disorder (2018)	0.7	1.2	4.5	-0.0	-2.0	0.2	-0.0	-0.1	-1.1	-0.9	-2.1	-1.2	-1.1	-1.3	0.6	-0.7
Worry (Nagel 2018)	0.7	1.5	7.1	1.4	1.6	2.7	2.2	0.9	0.0	0.5	0.6	-0.0	0.3	1.2	0.5	0.4
Age at First Birth	0.7	1.1	5.5	2.3	0.1	1.6	1.0	1.6	0.3	0.4	-0.7	-0.5	0.3	1.2	0.2	-0.2
Triglycerides	0.7	1.1	3.5	-1.9	-0.9	-1.2	-0.2	-1.8	0.0	-1.2	-0.4	-0.2	-0.8	-1.1	1.2	-0.3
Blood Platelet Count	0.7	8.1	28.2	5.3	0.8	4.3	2.6	3.9	1.8	2.0	1.4	1.6	2.6	2.9	1.9	2.4
Relative age of first facial hair	0.7	1.5	7.3	-0.3	-0.8	-2.7	-2.2	-0.1	1.0	1.0	0.8	0.7	1.2	0.8	0.4	1.1
Diabetes (father)	0.7	0.9	3.3	-1.1	-0.2	-0.2	0.1	-0.8	-1.7	-0.9	-0.8	-1.8	-1.0	0.3	-0.8	-0.7
Stomach or abdominal pain in last month	0.7	0.9	2.4	-0.5	-0.8	0.8	0.2	-0.1	-1.4	-1.4	-0.7	-1.6	-0.4	0.9	-0.4	-1.5
Number of incorrect matches in round	0.7	1.1	3.3	-1.6	1.8	-0.8	-1.3	-1.4	0.0	-0.1	1.1	0.6	0.9	0.3	-1.4	0.1
Hair/balding pattern: Pattern 2	0.7	0.9	3.3	-1.0	0.3	-0.8	-0.1	-1.5	-0.9	-0.3	-0.8	-0.2	-1.2	-1.3	-0.3	-1.8
Medication: Simvastatin	0.7	1.0	5.0	-0.7	-1.6	-0.6	-0.3	-0.6	-1.1	-2.2	-0.7	-1.5	-0.2	-0.3	-0.2	-0.3
Headache pain in last month	0.7	1.3	2.3	-1.0	-0.6	-0.9	-1.0	-1.1	-0.8	-1.2	-1.5	-1.0	-1.4	-1.2	1.2	-1.3
High blood pressure (siblings)	0.7	0.9	4.4	-0.9	-0.9	-2.1	-0.9	-1.1	0.4	-0.5	-0.9	0.3	-0.0	-1.3	1.0	-0.2
Forced vital capacity (FVC), Best measure	0.7	2.6	10.2	2.0	0.8	1.3	1.0	2.1	0.8	1.4	1.9	1.0	1.5	1.4	-3.2	0.5
Age at first live birth	0.7	1.3	4.8	0.4	0.3	1.3	1.0	0.7	0.5	1.2	1.9	1.6	0.9	0.0	-2.2	-0.0
Mouth/teeth dental problems: Loose teeth	0.7	0.8	3.0	-1.1	-0.3	-0.6	-1.4	-0.3	-1.0	-0.6	0.6	-1.0	-0.8	0.3	-1.7	-0.6
Emphysema/chronic bronchitis	0.7	0.8	3.2	0.4	-0.6	-0.2	-0.8	0.0	-1.8	-0.9	-0.0	-1.7	-0.3	-0.2	-1.5	-0.4
Medication: Seretide 50 evohaler	0.7	0.7	2.6	0.5	-0.8	-0.5	-0.2	0.5	-0.6	-0.9	-1.6	-1.6	-1.1	0.4	1.0	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	3.8	-0.7	-2.0	0.6	0.6	-0.9	1.1	-0.7	-0.9	0.5	-0.6	-0.4	1.0	0.8
Whole body fat-free mass	0.7	3.7	13.5	-2.4	-0.5	-2.3	-1.3	-2.7	-1.0	-1.3	0.4	-0.5	-0.6	-3.0	-3.7	-1.6
Medication: Gliclazide	0.7	0.8	3.7	-0.8	-0.1	-1.3	-1.9	-1.0	-0.6	-0.5	-0.8	-0.6	-0.7	-0.4	-0.1	-0.8
Illnesses of father: None of the above (group 1)	0.7	0.9	2.1	1.1	0.1	0.3	0.4	1.4	1.2	1.3	0.7	1.1	0.7	1.5	0.1	1.0
Number of operations (self-reported)	0.7	1.1	3.3	-0.5	-0.6	-0.0	-0.1	-1.1	-1.1	-1.5	-1.8	-1.0	-1.4	0.0	1.5	-0.6
Heart disease (siblings)	0.7	0.8	3.5	-1.4	0.1	-0.8	-1.2	-1.9	-0.2	-1.6	-0.2	-0.2	-0.0	-0.3	0.8	0.5
Neuroticism	0.6	1.4	4.7	-0.3	0.2	0.5	0.1	-0.4	-1.0	-1.4	-1.7	-1.3	-2.2	0.3	1.3	-2.0
Hearing difficulty/problems: Yes	0.6	0.9	2.8	0.1	-0.7	1.4	0.3	-0.2	-1.4	-0.7	-1.1	-1.7	-1.2	-0.5	0.3	-0.6
Maternal smoking around birth	0.6	0.9	2.9	-1.1	0.7	-1.4	-0.9	-1.2	-1.0	-1.7	-0.3	-1.5	-0.1	-0.0	0.0	-0.3
Hayfever, allergic rhinitis or eczema	0.6	1.4	2.2	-0.2	1.3	-1.2	-1.1	-1.1	-1.4	-1.5	0.5	-1.3	-0.9	-1.5	-1.3	-1.4
Diverticular disease/diverticulitis (self-reported)	0.6	0.8	1.9	-0.9	-0.2	-1.1	-1.0	-1.3	-0.5	-0.9	-0.5	-0.5	-0.7	-1.0	0.4	-1.4
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	1.9	0.8	0.7	-0.2	0.0	0.6	0.8	0.6	1.0	1.0	1.0	1.2	0.2	1.4
Standing height	0.6	5.6	28.4	-1.8	0.4	-2.1	-1.3	-2.8	-1.4	-0.2	1.4	-0.9	0.3	-4.1	-5.3	-2.3
Hair/balding pattern: Pattern 4	0.6	1.4	5.2	0.5	0.9	2.3	2.3	0.5	-0.3	-0.2	-1.0	-0.1	-0.5	0.9	2.2	0.0
Comparative body size at age 10	0.6	1.8	5.0	-2.2	-0.5	-1.4	-1.5	-2.2	-0.4	-1.6	-0.3	-0.3	-1.4	-1.9	0.5	-0.1
Knee pain experienced in last month	0.6	1.0	2.7	-1.3	0.7	-0.7	-0.9	-0.9	-0.9	-1.7	-1.5	-0.8	-1.2	0.1	-0.1	-0.4
Mood swings	0.6	1.1	4.8	-0.7	0.3	-0.5	-1.0	-0.8	-1.3	-0.9	-0.9	-1.0	-1.7	-0.6	-0.3	-2.2
Eye problems/disorders: Cataract	0.6	0.7	4.2	-0.5	-1.3	0.1	0.4	-1.0	0.3	0.4	0.6	1.1	0.3	-2.0	-0.5	0.2
Whole body water mass	0.6	3.7	13.1	-2.4	-0.5	-2.2	-1.3	-2.6	-1.0	-1.4	0.4	-0.6	-0.6	-2.9	-3.6	-1.6
Age started oral contraceptive pill	0.6	0.8	2.4	0.0	1.5	-1.2	0.3	-0.1	1.1	0.9	0.7	1.6	0.8	-0.0	0.4	0.9
Reaction Time	0.5	0.9	2.5	1.6	0.6	0.9	1.4	1.1	0.5	1.3	0.4	0.5	0.7	-0.6	0.8	0.7
Height	0.5	9.0	28.0	-2.9	-1.6	-3.4	-2.4	-4.0	-2.4	-0.2	-0.2	-1.5	-1.4	-4.3	-5.3	-3.9
Cardiovascular Disease	0.5	1.6	5.8	-2.4	-1.5	-1.7	-1.0	-1.4	0.4	-1.3	-1.2	-0.3	-0.3	-1.4	1.3	0.3
Sensitivity / hurt feelings	0.5	0.9	3.1	-0.2	1.2	-0.7	-1.8	-0.5	-0.0	0.1	-0.4	0.6	-1.6	0.1	1.2	-1.2
Supplements: Glucosamine	0.5	0.7	2.5	-1.0	-1.1	-1.6	-0.8	-0.7	-0.3	0.0	-0.8	-0.3	-0.1	-0.6	1.2	0.5
Medication: Atenolol	0.5	0.6	1.6	0.5	-0.9	0.7	0.7	1.2	0.7	0.7	0.1	0.8	1.0	0.9	-1.0	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	3.9	-0.8	-0.3	0.4	-0.5	-1.6	-0.8	-2.0	0.5	-0.8	-1.1	-1.8	-1.0	-1.0
Qualifications: None of the above	0.5	1.0	4.5	0.7	1.6	-0.3	0.1	0.5	0.3	-0.3	-0.9	0.3	-0.1	1.8	2.1	0.8
Heart attack	0.5	0.7	2.1	-0.2	-1.4	-0.0	-1.2	0.0	-0.9	-0.7	-0.6	-1.1	-0.2	0.1	-1.4	-0.2
Trunk fat-free mass	0.5	2.7	11.2	-2.0	-0.4	-1.7	-0.5	-2.2	-0.5	-0.8	0.5	-0.1	-0.3	-2.9	-3.3	-1.3
Time employed in main current job	0.5	0.6	3.2	-0.1	-0.8	-0.1	-0.4	0.1	-0.1	-0.5	-1.8	-0.5	-0.6	-0.6	1.4	-0.4
Falls in the last year	0.5	0.7	2.4	-1.1	-0.2	-0.9	-1.0	-0.4	1.0	1.1	0.6	1.6	0.0	0.0	-0.7	0.2
Number of live births	0.5	0.7	1.8	0.4	1.3	0.4	0.7	0.4	0.5	-0.2	0.4	0.0	1.2	1.3	1.2	1.3
Trunk predicted mass	0.5	2.8	11.7	-2.1	-0.4	-1.6	-0.5	-2.3	-0.6	-0.8	0.5	-0.1	-0.4	-2.9	-3.4	-1.4
Loud music exposure frequency	0.5	0.6	1.4	0.2	1.1	0.5	-0.2	0.6	-0.7	-0.5	0.0	-0.4	-1.0	1.2	-1.1	-0.9
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	4.0	-0.3	0.1	-0.4	-0.1	-0.0	1.1	1.0	-0.0	0.8	0.1	0.8	2.0	0.7
Birth weight	0.5	1.1	4.1	2.0	0.9	1.3	0.7	1.3	1.1	1.1	0.8	1.5	0.3	0.3	-0.6	-0.2
Arm fat-free mass (right)	0.5	2.3	12.1	-1.8	0.0	-1.9	-1.0	-2.0	-0.3	-0.8	1.0	0.1	0.2	-2.0	-3.5	-0.9
Qualifications: College or University degree	0.5	1.6	13.1	0.2	0.3	0.6	-0.7	0.1	-1.4	0.1	1.8	-0.4	0.1	-0.1	-3.6	-0.8
Medication: Omeprazole	0.5	0.6	2.0	1.4	-0.5	-1.0	-0.9	0.9	0.2	0.7	-0.2	0.2	0.4	1.3	0.1	0.4
Arm predicted mass (right)	0.5	2.3	10.0	-2.0	-0.3	-2.0	-0.9	-2.2	-0.3	-0.9	0.7	0.1	-0.1	-2.1	-3.2	-1.0
Pulse rate, automated reading	0.5	1.7	4.8	-1.8	-1.7	-2.0	-2.2	-2.0	0.5	0.4	0.9	0.1	0.8	-0.8	-0.2	0.7
Handedness (chirality/laterality): Left-handed	0.5	0.7	2.0	0.8	0.8	1.4	0.9	0.4	-0.1	0.8	0.3	0.7	0.9	-0.9	0.9	0.7
Qualifications: nursing, teaching	0.5	0.8	3.3	1.8	0.8	0.7	0.3	1.2	-0.3	0.2	0.7	-0.6	0.5	0.2	-1.4	-0.7
Mineral and other dietary supplements	0.5	0.7	3.5	1.9	0.1	0.8	0.1	1.3	-0.3	0.2	1.0	-0.2	-0.0	0.9	-1.3	-0.2
Commuting to job workplace: Public transport	0.5	0.6	2.1	-0.1	1.0	-0.9	-0.8	-0.5	-0.7	-0.9	0.6	-0.1	-0.2	-0.4	-0.9	-1.5
Supplements: Fish oil (including cod liver oil)	0.5	0.7	3.8	-0.6	-0.0	-1.1	-0.3	-0.1	0.6	0.1	-1.9	0.5	-0.1	-0.2	1.6	-0.2
Ever smoked	0.5	0.9	2.2	1.0	-1.1	-0.7	-0.6	0.5	-1.4	-0.2	-1.1	-0.8	-1.1	-0.3	-0.7	-1.5
Arm fat-free mass (left)	0.5	2.4	9.4	-1.9	-0.2	-2.0	-1.0	-2.2	-0.5	-1.1	0.5	-0.1	-0.2	-2.3	-3.1	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	3.5	0.8	-0.1	-1.9	-1.6	-0.1	0.1	0.6	0.1	0.2	0.3	0.6	0.1	0.0
Heart attack/myocardial infarction (self-reported)	0.5	0.7	3.1	-0.3	-1.1	-0.1	-1.4	-0.1	-0.9	-0.7	-0.3	-1.0	-0.1	0.1	-1.8	-0.2
Arm predicted mass (left)	0.5	2.3	9.2	-1.9	0.0	-1.8	-0.8	-2.3	-0.3	-1.0	0.7	-0.0	-0.2	-2.5	-3.0	-0.9
Bipolar Disorder or Schizophrenia	0.4	1.0	3.2	1.3	0.1	1.8	1.4	1.1	-0.0	0.6	-0.6	-0.2	0.6	0.9	1.8	0.7
Intelligence (Savage-Jansen 2018)	0.4	1.2	3.0	1.4	-0.9	1.3	1.1	1.3	-0.3	-0.2	-1.2	-1.1	-0.5	1.7	1.6	-0.1
Neuroticism (Nagel 2018)	0.4	0.9	2.6	-0.6	1.2	0.3	-0.1	-0.9	-1.1	-1.1	-0.8	-1.2	-1.5	0.3	0.4	-1.6
Ulcerative Colitis (UC)	0.4	0.7	3.2	-1.6	-1.8	-0.2	-0.6	-1.1	0.5	-0.7	-0.8	-0.1	-0.5	-0.2	0.1	-0.4
Breast Cancer	0.4	1.0	3.8	-1.2	-0.6	-2.0	-1.3	-1.6	0.0	-0.8	-0.7	0.1	-0.3	-1.2	1.0	-0.5
Prostate Cancer	0.4	0.5	3.1	-0.1	0.3	0.5	-0.0	-0.1	-0.5	0.2	-1.1	-0.6	-0.8	-1.8	0.3	-0.7
HbA1C	0.4	0.4	2.1	0.7	0.2	0.2	0.3	0.4	0.4	0.3	0.5	0.4	1.5	0.0	0.5	1.2
Hand grip strength (left)	0.4	1.1	7.0	0.7	0.5	0.0	0.0	0.5	0.8	0.1	1.5	1.2	1.3	-0.6	-2.6	-0.2
Hand grip strength (right)	0.4	1.1	5.7	1.3	0.5	0.3	0.5	0.9	0.8	0.8	1.2	1.0	1.2	-0.4	-2.4	-0.2
Qualifications: CSEs or equivalent	0.4	0.5	2.0	0.3	-0.7	0.8	0.2	1.2	1.0	0.8	0.6	0.4	0.4	-0.0	-0.1	1.4
Chronic bronchitis/emphysema (father)	0.4	0.5	0.9	-0.4	-0.5	-0.9	-0.9	-0.3	1.0	0.7	0.1	0.9	0.9	-0.2	0.7	0.5
High blood pressure (mother)	0.4	0.6	1.6	0.6	1.1	0.1	1.3	0.7	0.9	0.9	0.8	0.5	0.9	0.5	0.1	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	1.2	-0.7	0.5	-0.2	-0.7	-1.0	-1.0	-0.7	-0.7	-1.0	-1.0	0.3	1.1	-1.0
Impedance of arm (right)	0.4	1.7	4.7	-0.6	0.5	-1.4	-2.2	-1.4	-1.9	-0.7	-0.6	-1.6	-0.7	-2.1	0.0	-0.9
Father’s age at death	0.4	0.5	2.6	0.1	-0.2	0.0	0.5	0.1	-0.5	0.2	-1.6	-0.3	-0.7	0.4	1.5	-0.3
Illnesses of mother	0.4	0.5	1.1	0.7	-0.3	1.0	-0.6	0.4	-1.0	-0.6	-0.4	-0.9	-1.0	0.3	-0.6	-0.5
Impedance of arm (left)	0.4	1.9	6.2	-0.6	0.1	-2.0	-2.5	-1.5	-1.8	-0.7	-0.3	-1.8	-0.4	-1.9	-0.2	-0.9
Tense / ‘highly strung’	0.4	0.7	2.9	-0.3	1.4	0.1	0.2	-0.3	0.8	0.9	1.7	1.1	0.5	-0.5	0.1	0.3
Glaucoma (self-reported)	0.4	0.5	2.5	0.8	0.4	0.2	-0.1	0.8	0.3	0.1	0.6	0.1	0.9	1.6	0.5	0.7
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	2.9	-0.7	-0.5	-1.7	-1.6	-1.1	0.4	-1.3	0.1	-0.0	0.4	-1.1	0.5	0.3
Number of children fathered	0.4	0.4	1.4	-0.1	0.4	-0.3	0.1	0.2	-1.1	0.6	-0.4	-1.2	-0.2	0.9	-0.6	-0.6
Eye problems/disorders: None of the above	0.4	0.5	2.0	0.2	1.3	0.0	-0.1	0.4	1.0	0.6	-0.1	0.1	0.8	0.1	1.4	0.7
Medication: Blood pressure	0.4	0.7	1.7	-1.3	-1.3	-1.1	-1.1	-0.4	-0.6	-0.8	-0.5	-0.6	-0.4	-0.2	-0.7	-0.9
Medication: Aspirin	0.4	0.6	2.1	-0.7	0.8	-0.2	-1.4	-1.1	-0.2	-0.8	0.5	-0.4	0.6	-0.8	-1.0	0.4
Illnesses of father: Heart disease	0.4	0.6	1.6	-0.4	1.3	-0.4	-0.8	-0.9	-0.8	-0.9	0.7	-0.4	0.9	-0.4	-1.0	-0.2
Average weekly red wine intake	0.4	0.6	1.8	0.3	0.8	0.2	-0.1	0.6	0.3	1.1	1.0	0.6	1.4	1.0	-0.2	1.2
Ever had bowel cancer screening	0.4	0.4	1.1	-0.5	-0.8	-0.6	-0.9	-0.8	-0.7	-0.4	-0.8	-0.6	-0.6	-0.1	1.0	0.2
Friendships satisfaction	0.4	0.5	2.1	0.2	0.9	0.6	-0.9	0.4	0.4	0.9	0.8	0.4	0.2	0.1	-1.4	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.2	-1.1	1.1	-1.1	-0.8	-0.9	0.2	0.6	0.3	0.6	0.3	-0.3	0.3	0.2
Medication: Aspirin	0.4	0.5	1.3	-0.4	0.5	-0.1	-1.2	-0.9	-0.0	-0.5	0.8	-0.3	1.0	-0.9	-1.0	0.8
Illnesses of father: High blood pressure	0.4	0.5	1.9	0.5	1.4	0.1	-0.3	0.3	-1.1	0.5	-0.2	-0.4	-0.7	-0.8	-0.3	-1.1
Risk taking	0.4	0.5	2.0	-0.2	-1.4	-1.1	-1.4	-0.4	0.7	-0.1	-0.3	0.5	0.2	-0.6	0.2	0.1
Systolic blood pressure, automated reading	0.3	0.8	4.9	-1.4	-0.7	-0.0	0.3	-0.8	0.1	-1.0	-1.2	0.1	-0.8	0.2	2.2	-0.0
Average weekly fortified wine intake	0.3	0.3	0.9	0.6	0.0	0.8	0.4	-0.2	-0.2	0.1	0.5	0.2	0.4	-0.8	-0.9	-1.0
Nervous feelings	0.3	0.5	2.1	0.8	0.6	1.4	1.3	0.3	-0.9	0.0	-0.1	-0.5	-0.2	0.3	0.2	-0.6
Fluid intelligence score	0.3	0.7	2.7	1.2	-0.9	1.2	0.1	0.6	-0.7	0.0	-1.0	-1.6	-0.5	0.5	-0.2	-0.4
Happiness	0.3	0.3	1.1	-0.3	0.8	0.2	0.2	-0.1	0.8	0.9	0.7	1.1	0.0	0.1	-0.2	0.2
Qualifications: A levels/AS levels or equivalent	0.3	0.7	2.7	1.2	-0.0	1.6	0.9	1.1	0.3	1.2	0.1	0.5	0.4	0.5	-0.3	0.3
Medication: Lansoprazole	0.3	0.3	1.0	-0.4	0.7	1.0	0.7	-0.9	-0.2	-0.1	-0.3	-0.2	0.1	-0.7	0.4	0.2
Exposure to tobacco smoke at home	0.3	0.4	1.5	-0.4	1.2	0.6	0.8	-0.3	-0.5	-0.2	-0.1	-0.4	0.2	-0.9	-0.9	-0.5
Medication: Amlodipine	0.3	0.5	3.0	0.1	-0.4	-0.1	0.4	0.6	0.4	-0.1	0.8	0.1	1.7	0.7	-0.1	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.8	-0.6	0.0	0.8	-0.0	-0.1	-0.8	-1.4	0.2	-0.6	-0.3	-0.0	0.2	0.3
Suffer from ‘nerves’	0.3	0.5	2.4	-0.4	1.5	0.8	0.7	-0.8	-0.9	-0.6	0.4	-0.5	-0.6	-0.4	0.0	-0.7
Age at last live birth	0.3	0.4	1.5	-0.4	-0.3	0.7	0.4	-0.1	0.3	0.7	1.1	1.0	0.3	0.2	-1.2	-0.2
Hypertension (Self-reported)	0.3	0.8	2.8	-0.9	-1.7	-1.2	-0.2	-0.4	0.4	-0.6	-1.2	0.1	-0.4	-0.1	1.5	-0.1
Average weekly champagne plus white wine intake	0.3	0.3	1.6	-0.4	0.3	-0.1	-0.3	-0.6	-0.8	-0.3	-0.2	-0.7	-0.1	-1.3	-0.6	-0.8
Mother’s age at death	0.3	0.4	1.2	0.0	0.3	0.9	0.1	-0.5	-0.5	0.2	0.8	0.1	0.4	-1.0	-1.1	0.2
Eye problems/disorders: Glaucoma	0.3	0.3	1.3	0.4	-0.8	-0.3	0.2	0.5	0.3	-0.6	-0.1	-0.3	0.4	1.1	1.1	0.6
Medication: Blood pressure	0.3	0.5	1.9	1.4	0.2	1.0	1.1	1.1	0.4	0.7	-0.4	0.1	0.6	-0.1	0.7	0.3
High cholesterol (Self-reported)	0.3	0.6	2.5	-0.3	-0.2	-0.3	-0.2	-0.3	0.3	-1.2	0.4	-0.2	1.4	0.3	0.9	1.6
Commuting to job workplace: Cycle	0.3	0.4	1.2	-0.4	-1.1	0.0	-0.1	-0.1	1.0	-0.0	0.6	0.8	0.8	-0.3	-0.5	-0.0
Crohns Disease (2017)	0.2	0.3	1.4	-1.2	0.3	-0.1	-0.8	-0.9	-0.3	-0.8	-0.4	-0.5	-0.0	-0.5	0.2	-0.5
Irritable Bowel Disease (IBD)	0.2	0.5	2.3	-1.5	-1.0	-0.2	-0.9	-1.2	0.3	-0.7	-0.4	-0.2	-0.2	-0.3	0.1	-0.4
Waist Hip Ratio (WHR)	0.2	0.8	3.3	-0.9	-0.8	-1.7	-1.8	-0.5	0.1	1.0	0.1	0.4	0.1	-0.7	-0.1	0.9
Systolic Blood Pressure	0.2	0.9	3.7	-1.9	-0.9	0.3	0.5	-1.0	0.8	-0.0	-0.6	1.0	-0.7	-0.3	1.9	-0.5
Hypothyroidism (self reported)	0.2	0.5	1.9	0.1	0.3	-1.1	-1.1	-0.9	0.2	-1.4	0.1	-0.4	0.5	-0.7	0.8	0.5
Lung FEV1/FVC ratio	0.2	0.9	2.8	0.4	-1.7	0.6	-0.4	1.1	1.2	0.8	-0.3	1.2	0.9	0.9	-1.0	1.0
Angina	0.2	0.3	0.8	-0.0	-0.9	0.1	-0.5	0.5	-0.6	-0.1	-0.4	-0.2	0.1	0.8	-0.9	0.1
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	1.0	-0.4	-0.7	0.1	-0.4	-0.1	-0.2	-0.8	-0.4	0.4	-0.6	-0.2	1.0	0.3
High blood pressure	0.2	0.5	1.6	-0.8	-1.1	-1.0	-0.2	-0.3	0.3	-0.7	-1.2	-0.1	-0.5	0.1	1.3	-0.4
Medication: Levothyroxine sodium	0.2	0.4	2.1	0.3	-0.1	-1.1	-1.4	-0.5	0.2	-1.1	-0.2	-0.1	-0.0	-0.6	0.4	0.1
Impedance of leg (left)	0.2	1.1	3.6	1.2	1.2	1.2	1.0	1.0	0.8	1.9	0.7	0.6	1.2	0.2	1.1	0.8
Past tobacco smoking	0.2	0.3	1.1	-0.6	1.0	0.5	0.6	-0.2	0.6	-0.3	0.7	-0.2	0.1	0.2	0.4	0.7
Hearing difficulty/problems with background noise	0.2	0.4	2.0	0.0	0.7	0.6	0.1	-0.2	-0.1	0.7	1.0	0.3	0.2	-0.6	-1.4	0.1
Angina (self-reported)	0.2	0.3	1.0	-0.3	-1.0	-0.1	-0.8	0.2	-0.6	-0.3	-0.4	-0.2	0.1	0.7	-0.9	0.1
Mean time to correctly identify matches	0.2	0.3	1.4	1.2	-0.2	0.4	0.9	0.7	0.0	0.7	-0.2	0.1	0.3	-0.5	0.5	0.4
Smoking status: Previous	0.2	0.3	1.1	0.5	-1.0	-0.2	-0.2	0.2	0.2	0.6	-0.5	1.1	0.4	-0.0	0.4	-0.1
Osteoporosis (self-reported)	0.2	0.2	0.9	-0.3	-0.0	-0.1	0.0	-0.4	0.3	0.9	0.8	0.3	0.7	0.1	-0.9	0.3
Medication: Bendroflumethiazide	0.2	0.3	0.7	-0.5	0.7	-0.6	-0.7	-0.1	-0.1	0.6	-0.0	0.2	-0.8	-0.6	-0.6	-0.7
Diastolic blood pressure, automated reading	0.2	0.5	2.0	-0.9	-0.9	-1.1	-0.4	-1.4	0.7	-0.3	0.3	0.6	-0.1	-0.8	0.4	-0.1
Vascular/heart problems diagnosed by doctor	0.2	0.4	1.3	0.6	1.1	0.9	0.3	0.3	-0.1	0.8	1.0	0.2	0.3	-0.0	-0.9	0.3
Body Mass Index (BMI) (2010)	0.1	0.1	0.6	-0.3	-0.7	0.0	0.2	-0.0	-0.0	0.2	0.8	0.4	0.4	-0.0	0.0	0.5
Crohns Disease (2012)	0.1	0.2	0.7	-0.1	-0.0	-0.1	-0.6	0.1	-0.3	-0.7	-0.3	-0.8	-0.0	0.0	0.2	0.2
Blood Eosinophil Count	0.1	0.8	3.3	0.8	0.4	-1.4	-1.8	0.3	-0.5	0.3	0.3	-0.7	0.6	0.3	-1.1	1.5
Blood Red Count	0.1	0.6	3.5	0.2	-0.4	0.2	0.8	-0.5	0.2	0.0	0.8	0.2	-0.0	-1.5	-1.9	0.3
Chronotype (morning person)	0.1	0.1	0.4	0.4	0.2	-0.0	-0.6	0.5	-0.4	0.1	0.6	-0.3	-0.1	0.0	-0.5	0.5
Tanning	0.1	1.1	3.3	-1.8	-0.7	-1.5	-0.5	-1.8	0.4	-0.2	1.0	0.6	0.1	-1.8	0.7	0.0
Impedance of leg (right)	0.1	0.4	1.5	0.7	0.8	0.4	0.2	0.3	0.1	1.2	0.1	-0.1	0.6	-0.2	1.2	0.1
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.8	-0.4	-0.7	0.1	-0.0	-0.6	-0.2	-0.7	0.0	0.2	-0.1	-0.9	0.0	-0.3
Medication: Ramipril	0.1	0.1	0.3	0.5	-0.5	-0.2	0.0	0.5	0.1	-0.4	0.2	0.2	0.3	-0.2	-0.5	-0.2
Alcohol intake frequency.	0.1	0.3	0.9	-0.5	0.6	0.8	0.9	-0.4	0.5	-0.9	-0.0	0.0	-0.5	-0.2	0.1	-0.2
Medication: Atorvastatin	0.1	0.2	0.6	-0.0	-0.0	0.3	-0.8	-0.3	0.3	0.1	-0.4	0.6	-0.4	0.1	-0.2	-0.8
Impedance of whole body	0.1	0.4	1.5	0.3	0.6	-0.6	-1.2	-0.4	-0.6	0.7	0.2	-0.7	0.4	-1.0	0.3	-0.2
Hair Pigment	0.0	0.3	1.6	0.6	0.5	-0.1	-0.5	-0.2	-0.2	-0.0	-0.3	-0.2	-0.8	-1.2	0.7	-0.4

Hub : Genes

DMGDH

Models

Trait associations