Best TWAS P=3.28e-09 · Best GWAS P=2.19e-12 conditioned to 0.0219
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Stomach | HOTAIRM1 | 0.14 | 0.12 | lasso | 5 | 0.15 | 8.8e-08 | 5.2 | 5.7 | 1.5e-08 | 0.77 | 0.07 | 0.88 | FALSE |
| 2 | YFS | Blood | HOXA9 | 0.06 | 0.05 | lasso | 6 | 0.06 | 2.0e-19 | 7.0 | -5.4 | 5.5e-08 | -0.88 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | HOXA10 | 0.02 | 0.01 | blup | 53 | 0.01 | 9.0e-03 | 6.7 | -5.6 | 1.8e-08 | -0.13 | 0.02 | 0.59 | TRUE |
| 4 | The Cancer Genome Atlas | Esophageal Carcinoma | EVX1 | 0.16 | 0.02 | blup | 50 | 0.12 | 1.4e-04 | -0.9 | 5.5 | 4.2e-08 | 0.15 | 0.01 | 0.35 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | HOXA9 | 0.04 | 0.04 | lasso | 2 | 0.04 | 1.4e-04 | 5.6 | -5.9 | 3.3e-09 | -0.91 | 0.01 | 0.98 | TRUE |