Best TWAS P=1.35e-08 · Best GWAS P=3.55e-09 conditioned to 0.0304
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | ZMIZ2 | 0.12 | 0.09 | lasso | 4 | 0.06 | 2.3e-05 | -4.7 | -5.1 | 2.9e-07 | 0.68 | 0.03 | 0.97 | FALSE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PPIA | 0.05 | 0.02 | enet | 5 | 0.03 | 7.7e-05 | -5.9 | -5.7 | 1.4e-08 | 0.82 | 0.00 | 0.95 | TRUE |