Best TWAS P=3.34e-08 · Best GWAS P=8.77e-09 conditioned to 0.000183
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | GRID1 | 0.09 | 0.04 | lasso | 9 | 0.03 | 2.1e-07 | -5.4 | -5.5 | 3.3e-08 | -0.43 | 0.04 | 0.96 | TRUE |
2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | GRID1 | 0.07 | 0.03 | lasso | 4 | 0.02 | 9.7e-04 | -5.4 | -5.3 | 1.4e-07 | -0.37 | 0.04 | 0.93 | FALSE |