Best TWAS P=4.53e-12 · Best GWAS P=9.49e-18 conditioned to 0.64
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ADAMTS14 | 0.28 | 0.24 | bslmm | 733 | 0.35 | 7.9e-44 | -2.4 | 6.8 | 7.4e-12 | 0.81 | 0.08 | 0.92 | FALSE |
| 2 | GTEx | Artery Tibial | PCBD1 | 0.19 | 0.01 | lasso | 6 | 0.01 | 3.0e-02 | -4.7 | 5.7 | 1.5e-08 | 0.44 | 0.11 | 0.22 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | ADAMTS14 | 0.38 | 0.35 | bslmm | 710 | 0.47 | 3.9e-67 | 8.5 | 6.9 | 4.5e-12 | 0.86 | 0.00 | 1.00 | TRUE |