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chr9:14,857,740-16,758,776

Best TWAS P=6.06e-25 · Best GWAS P=2.61e-20 conditioned to 0.706

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Aorta	CCDC171	0.18	0.05	lasso	5	0.08	2.2e-05	-4.0	-5.7	1.4e-08	0.31	0.34	0.06	FALSE
2	GTEx	Artery Tibial	CCDC171	0.10	0.09	enet	9	0.12	7.2e-10	4.4	-5.7	1.0e-08	0.60	0.90	0.09	FALSE
3	GTEx	Brain Caudate basal ganglia	CCDC171	0.30	0.18	lasso	4	0.23	2.4e-07	8.0	-8.9	8.0e-19	0.95	0.04	0.96	FALSE
4	GTEx	Brain Cerebellar Hemisphere	CCDC171	0.46	0.19	lasso	7	0.23	1.3e-06	-9.2	-10.3	6.1e-25	0.91	0.03	0.97	TRUE
5	GTEx	Brain Cerebellum	CCDC171	0.46	0.22	lasso	7	0.15	3.4e-05	-8.8	-9.4	5.4e-21	0.97	0.02	0.98	FALSE
6	GTEx	Brain Cortex	CCDC171	0.26	0.15	lasso	2	0.16	2.8e-05	-7.4	-8.2	2.2e-16	0.92	0.06	0.91	FALSE
7	GTEx	Brain Frontal Cortex BA9	CCDC171	0.27	0.18	enet	10	0.19	8.3e-06	8.1	-7.9	2.0e-15	0.83	0.07	0.88	FALSE
8	GTEx	Brain Hypothalamus	CCDC171	0.32	0.17	enet	6	0.09	4.0e-03	-9.2	-7.6	2.3e-14	0.91	0.02	0.91	FALSE
9	GTEx	Lung	CCDC171	0.13	0.03	enet	9	0.01	5.0e-02	5.6	-7.3	3.6e-13	0.72	0.46	0.28	FALSE
10	GTEx	Nerve Tibial	CCDC171	0.25	0.16	lasso	6	0.14	2.1e-10	-8.7	-8.7	2.2e-18	0.96	0.11	0.89	FALSE
11	GTEx	Ovary	CCDC171	0.21	0.19	lasso	4	0.16	7.7e-05	7.8	7.5	9.5e-14	-0.85	0.19	0.42	TRUE
12	GTEx	Pituitary	CCDC171	0.28	0.16	enet	29	0.12	5.2e-04	8.0	-8.4	3.8e-17	0.90	0.18	0.75	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	CCDC171	0.20	0.04	enet	45	0.06	4.9e-04	8.1	-5.4	5.7e-08	0.40	0.62	0.27	FALSE
14	GTEx	Skin Sun Exposed Lower leg	CCDC171	0.14	0.09	enet	13	0.12	1.9e-10	7.8	-6.2	4.2e-10	0.63	0.98	0.01	FALSE
15	METSIM	Adipose	CCDC171	0.03	0.00	blup	828	0.01	4.0e-02	8.0	-7.5	6.9e-14	0.79	0.19	0.60	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	CCDC171	0.14	0.11	enet	21	0.11	8.3e-14	8.1	-8.5	2.3e-17	0.81	0.90	0.10	FALSE
17	The Cancer Genome Atlas	Soft Tissue Sarcoma	C9orf93	0.06	0.05	lasso	3	0.03	5.3e-03	7.2	-6.2	5.2e-10	0.70	0.14	0.23	FALSE