Best TWAS P=2.09e-08 · Best GWAS P=2.27e-08 conditioned to 0.000397
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | TTLL7 | 0.11 | 0.01 | enet | 13 | 0.01 | 3.1e-02 | -5.2 | -5.6 | 2.1e-08 | 0.44 | 0.06 | 0.94 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | TTLL7 | 0.10 | 0.10 | lasso | 8 | 0.09 | 4.3e-12 | -5.4 | 5.4 | 5.4e-08 | -0.47 | 0.04 | 0.96 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | C1orf52 | 0.05 | 0.02 | blup | 564 | 0.03 | 9.5e-05 | 4.0 | 5.2 | 1.7e-07 | 0.01 | 0.18 | 0.65 | TRUE |