Best TWAS P=1.17e-09 · Best GWAS P=1.68e-07 conditioned to 0.0488
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | CTD-3076O17.1 | 0.22 | 0.05 | lasso | 6 | 0.04 | 2.9e-04 | -3.2 | -5.4 | 6.3e-08 | 0.49 | 0.10 | 0.85 | FALSE |
2 | GTEx | Adipose Visceral Omentum | CTD-3076O17.1 | 0.21 | 0.00 | lasso | 6 | 0.00 | 6.2e-01 | -4.7 | -6.1 | 1.2e-09 | 0.60 | 0.04 | 0.61 | TRUE |
3 | GTEx | Heart Atrial Appendage | ADAMTS17 | 0.22 | 0.00 | lasso | 4 | 0.09 | 9.6e-05 | -4.2 | -6.0 | 2.2e-09 | 0.38 | 0.06 | 0.38 | FALSE |
4 | GTEx | Testis | CTD-3076O17.1 | 0.45 | 0.17 | enet | 19 | 0.14 | 1.0e-06 | -4.7 | -5.3 | 1.1e-07 | 0.74 | 0.04 | 0.95 | FALSE |