[Hub]/) : Traits : Trunk fat mass :

chr16:86,671-3,010,510

Best TWAS P=1.97e-12 · Best GWAS P=3.59e-13 conditioned to 0.882

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SLC9A3R2 0.15 0.09 enet 7 0.10 7.8e-12 -4.8 5.4 6.8e-08 -0.59 0.98 0.02 FALSE
2 GTEx Artery Aorta TSC2 0.08 0.02 enet 7 0.03 5.0e-03 -5.7 5.7 1.4e-08 -0.52 0.14 0.33 FALSE
3 GTEx Brain Cerebellar Hemisphere CCDC78 0.21 0.12 enet 12 0.12 6.2e-04 -4.0 -5.6 1.9e-08 0.01 0.14 0.38 TRUE
4 GTEx Nerve Tibial AXIN1 0.11 0.09 lasso 2 0.06 3.9e-05 -5.9 5.2 1.7e-07 -0.04 0.01 0.99 FALSE
5 GTEx Nerve Tibial PDIA2 0.12 0.01 enet 13 0.06 4.4e-05 -5.7 5.7 1.4e-08 -0.05 0.01 0.99 FALSE
6 GTEx Nerve Tibial ARHGDIG 0.13 0.07 lasso 2 0.07 8.0e-06 -5.9 6.0 2.6e-09 -0.07 0.01 0.97 FALSE
7 GTEx Skin Sun Exposed Lower leg RNPS1 0.10 0.01 lasso 6 0.04 6.3e-04 3.3 -5.6 2.2e-08 0.32 0.07 0.80 FALSE
8 GTEx Testis AXIN1 0.36 0.29 lasso 3 0.28 4.3e-13 -5.9 -5.6 2.0e-08 0.04 0.01 0.99 FALSE
9 METSIM Adipose PKD1 0.06 0.02 bslmm 370 0.03 9.5e-06 -6.9 5.9 3.1e-09 -0.78 0.00 0.99 FALSE
10 ROSMAP Brain Pre-frontal Cortex SLC9A3R2 0.16 0.11 lasso 6 0.12 6.3e-15 -5.9 5.9 3.5e-09 -0.62 0.87 0.13 FALSE
11 ROSMAP Brain Pre-frontal Cortex MLST8 0.22 0.18 lasso 6 0.18 7.1e-23 5.5 6.3 2.9e-10 -0.49 0.98 0.02 FALSE
12 ROSMAP Brain Pre-frontal Cortex BRICD5 0.19 0.05 enet 36 0.06 4.5e-08 5.8 -5.2 2.0e-07 0.23 0.95 0.05 FALSE
13 ROSMAP Brain Pre-frontal Cortex PDIA2 0.15 0.07 lasso 8 0.10 5.2e-13 -4.8 -5.8 9.0e-09 0.04 0.04 0.96 FALSE
14 YFS Blood MLST8 0.12 0.06 bslmm 326 0.06 4.3e-20 -4.0 5.5 3.1e-08 -0.38 1.00 0.00 FALSE
15 YFS Blood TSC2 0.03 0.02 lasso 4 0.02 7.6e-08 -4.7 5.4 7.2e-08 -0.43 0.92 0.08 FALSE
16 The Cancer Genome Atlas Brain Lower Grade Glioma AXIN1 0.03 0.01 blup 88 0.01 7.7e-03 -5.8 6.5 5.9e-11 -0.03 0.01 0.79 TRUE
17 The Cancer Genome Atlas Brain Lower Grade Glioma CASKIN1 0.02 0.00 blup 38 0.01 4.5e-02 5.3 -7.0 2.0e-12 0.46 0.03 0.04 TRUE
18 The Cancer Genome Atlas Brain Lower Grade Glioma LOC100134368 0.03 0.00 enet 5 0.01 2.8e-02 -3.2 -5.8 4.9e-09 0.03 0.01 0.59 FALSE
19 The Cancer Genome Atlas Brain Lower Grade Glioma MLST8 0.07 0.07 enet 6 0.08 1.2e-09 -4.0 5.3 1.4e-07 -0.25 0.01 0.99 FALSE
20 The Cancer Genome Atlas Prostate Adenocarcinoma C16orf79 0.05 0.01 lasso 4 0.02 1.5e-03 5.3 -6.0 2.6e-09 0.24 0.01 0.94 FALSE
21 The Cancer Genome Atlas Prostate Adenocarcinoma LOC100134368 0.05 0.00 blup 48 0.04 2.5e-05 -4.4 -6.3 3.2e-10 0.04 0.02 0.85 FALSE
22 The Cancer Genome Atlas Thyroid Carcinoma CASKIN1 0.06 0.02 blup 38 0.04 1.5e-04 -7.3 -6.6 3.8e-11 0.81 0.00 0.98 FALSE
23 The Cancer Genome Atlas Thyroid Carcinoma LOC100134368 0.06 0.05 blup 47 0.07 3.9e-07 2.3 -5.1 3.1e-07 0.05 0.30 0.60 FALSE
24 The Cancer Genome Atlas Thyroid Carcinoma MLST8 0.09 0.07 enet 8 0.09 9.9e-09 5.8 5.6 1.7e-08 -0.30 0.00 1.00 FALSE
25 The Cancer Genome Atlas Thyroid Carcinoma SLC9A3R2 0.06 0.03 lasso 5 0.03 3.7e-04 -4.8 6.4 1.4e-10 -0.60 0.06 0.76 TRUE