[Hub]/) : Traits : Trunk fat mass :

chr1:112,312,154-114,367,116

Best TWAS P=1.2e-12 · Best GWAS P=4.61e-12 conditioned to 0.448

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex WNT2B 0.43 0.46 enet 44 0.47 7.4e-64 -6.9 -6.6 5.4e-11 0.93 0.01 0.99 FALSE
2 GTEx Brain Cortex WNT2B 0.36 0.19 lasso 5 0.23 5.5e-07 -6.7 -6.6 4.1e-11 0.89 0.02 0.98 FALSE
3 GTEx Brain Frontal Cortex BA9 WNT2B 0.29 0.28 lasso 3 0.29 2.6e-08 -6.9 -7.0 2.3e-12 0.93 0.01 0.99 FALSE
4 GTEx Pituitary ST7L 0.31 0.18 lasso 7 0.18 3.0e-05 -5.7 -6.6 3.6e-11 0.81 0.02 0.97 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic SLC16A1 0.12 0.00 lasso 5 0.04 5.0e-03 -6.7 5.2 1.6e-07 -0.80 0.02 0.90 FALSE
6 GTEx Skin Sun Exposed Lower leg MOV10 0.05 0.02 lasso 5 0.02 1.1e-02 -6.7 -6.4 1.5e-10 0.80 0.02 0.93 FALSE
7 GTEx Testis RLIMP2 0.35 0.00 enet 47 0.06 1.1e-03 2.0 5.5 3.7e-08 -0.33 0.18 0.09 FALSE
8 ROSMAP Brain Pre-frontal Cortex WNT2B 0.34 0.40 enet 30 0.42 1.5e-59 -6.7 -6.4 1.7e-10 0.93 0.01 0.99 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma MOV10 0.06 0.06 lasso 7 0.05 9.4e-06 -6.7 -7.1 1.2e-12 0.94 0.01 0.99 TRUE