Best TWAS P=2.1e-09 · Best GWAS P=5.79e-11 conditioned to 0.000808
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | TSEN15 | 0.23 | 0.18 | lasso | 9 | 0.18 | 4.7e-21 | 5.6 | 5.6 | 2.2e-08 | 0.90 | 0.12 | 0.88 | FALSE |
2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | GLT25D2 | 0.05 | 0.01 | enet | 10 | 0.04 | 6.3e-05 | 3.7 | -6.0 | 2.1e-09 | -0.69 | 0.00 | 0.95 | TRUE |