Best TWAS P=4.45e-10 · Best GWAS P=1.49e-08 conditioned to 0.0495
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ACYP2 | 0.06 | 0.02 | blup | 561 | 0.03 | 4.8e-05 | -4.9 | 6.2 | 4.5e-10 | -0.68 | 0.01 | 0.98 | TRUE |
| 2 | GTEx | Breast Mammary Tissue (Female) | HMGB1P31 | 0.19 | 0.06 | enet | 32 | 0.07 | 4.7e-03 | -2.9 | -5.2 | 2.0e-07 | 0.74 | 0.02 | 0.85 | FALSE |
| 3 | GTEx | Testis | HMGB1P31 | 0.17 | 0.01 | enet | 21 | 0.02 | 4.6e-02 | -2.1 | -5.6 | 2.7e-08 | 0.60 | 0.12 | 0.64 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | ERLEC1 | 0.03 | 0.00 | blup | 467 | 0.01 | 5.1e-03 | -4.1 | -5.3 | 1.3e-07 | 0.71 | 0.23 | 0.55 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ACYP2 | 0.06 | 0.04 | lasso | 3 | 0.03 | 1.3e-04 | -5.6 | 5.2 | 2.5e-07 | -0.96 | 0.00 | 1.00 | FALSE |