TWAS hub - ACYP2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0570	0.0220	2.3e-04	0.024	0.034	0.017	0.033	0.024	5.0e-04	4.8e-05	3.1e-03	5.6e-05	5.3e-04
2	GTEx	Cells Transformed fibroblasts	0.2000	0.0510	7.7e-10	0.094	NA	0.192	NA	0.180	1.7e-07	NA	2.5e-14	NA	1.7e-13
3	GTEx	Colon Sigmoid	0.3470	0.0860	9.6e-08	0.090	NA	0.184	NA	0.181	4.3e-04	NA	4.6e-07	NA	5.7e-07
4	GTEx	Colon Transverse	0.2650	0.0650	2.4e-09	0.318	NA	0.267	NA	0.056	1.0e-15	NA	4.8e-13	NA	1.1e-03
5	GTEx	Esophagus Gastroesophageal Junction	0.1620	0.0530	1.2e-04	0.174	NA	0.076	NA	0.064	7.3e-07	NA	1.0e-03	NA	2.5e-03
6	GTEx	Esophagus Mucosa	0.2540	0.0590	1.9e-12	0.215	NA	0.220	NA	0.245	2.1e-14	NA	9.2e-15	NA	1.9e-16
7	GTEx	Esophagus Muscularis	0.2370	0.0500	9.9e-14	0.251	NA	0.250	NA	0.243	2.2e-15	NA	2.5e-15	NA	6.3e-15
8	GTEx	Lung	0.1325	0.0388	5.0e-07	0.119	NA	0.083	NA	0.101	2.3e-09	NA	6.1e-07	NA	3.7e-08
9	GTEx	Muscle Skeletal	0.2339	0.0450	0.0e+00	0.254	NA	0.210	NA	0.252	7.5e-25	NA	2.4e-20	NA	1.4e-24
10	GTEx	Nerve Tibial	0.1237	0.0410	6.6e-05	0.042	NA	0.068	NA	0.061	6.1e-04	NA	1.4e-05	NA	3.9e-05
11	GTEx	Ovary	0.2690	0.0930	1.3e-03	0.162	NA	0.014	NA	0.077	8.7e-05	NA	1.4e-01	NA	6.2e-03
12	GTEx	Skin Not Sun Exposed Suprapubic	0.0930	0.0390	1.4e-03	0.100	NA	0.066	NA	0.088	4.1e-06	NA	1.7e-04	NA	1.5e-05
13	GTEx	Stomach	0.1610	0.0640	5.3e-04	0.044	NA	0.053	NA	0.057	3.7e-03	NA	1.5e-03	NA	1.1e-03
14	GTEx	Testis	0.1230	0.0490	9.0e-04	0.069	NA	0.054	NA	0.074	5.6e-04	NA	2.0e-03	NA	3.3e-04
15	GTEx	Thyroid	0.1300	0.0390	5.1e-07	0.057	NA	0.067	NA	0.076	3.4e-05	NA	7.9e-06	NA	1.8e-06
16	NTR	Blood	0.0247	0.0089	8.4e-06	0.020	0.012	0.018	0.013	0.017	3.8e-07	7.9e-05	8.9e-07	4.5e-05	2.5e-06
17	ROSMAP	Brain Pre-frontal Cortex	0.0932	0.0332	8.2e-06	0.023	0.021	0.023	0.026	0.031	5.3e-04	8.2e-04	5.2e-04	2.1e-04	6.3e-05
18	TCGA	Bladder Urothelial Carcinoma	0.0680	0.0380	5.2e-03	0.004	0.021	0.013	NA	0.026	1.4e-01	6.1e-03	2.5e-02	NA	2.7e-03
19	TCGA	Breast Invasive Carcinoma	0.0170	0.0090	4.4e-03	0.004	0.006	0.004	NA	0.003	3.5e-02	2.0e-02	4.1e-02	NA	7.6e-02
20	TCGA	Kidney Renal Clear Cell Carcinoma	0.0386	0.0218	8.2e-03	0.019	0.007	0.015	NA	0.009	2.5e-03	4.9e-02	6.6e-03	NA	2.7e-02
21	TCGA	Brain Lower Grade Glioma	0.0637	0.0323	5.4e-04	0.037	0.018	0.025	NA	0.032	4.0e-05	3.5e-03	6.5e-04	NA	1.3e-04
22	TCGA	Lung Squamous Cell Carcinoma	0.0742	0.0298	3.3e-04	0.019	0.021	0.044	NA	0.041	2.5e-03	1.8e-03	8.9e-06	NA	1.6e-05
23	TCGA	Prostate Adenocarcinoma	0.2072	0.0657	6.0e-12	0.154	0.125	0.154	NA	0.158	7.2e-16	5.9e-13	7.2e-16	NA	3.0e-16
24	TCGA	Thyroid Carcinoma	0.1550	0.0460	1.5e-08	0.085	0.094	0.117	NA	0.115	1.2e-08	2.2e-09	2.0e-11	NA	2.8e-11

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Other serious medical condition/disability diagnosed by doctor	6.9	9.0	18.9	-1.6	-3.4	-3.0	-3.3	-3.2	-3.7	-3.1	-3.4	2.2	-2.7	-3.6	-3.2	-3.6	-2.8	-2.7	-2.1	-2.4	-4.3	-0.9	-2.4	-0.8	-4.3	-3.2	-2.5
HDL Cholesterol	5.4	8.9	11.2	-3.3	-3.0	-3.3	-3.1	-3.2	-3.3	-3.1	-3.3	2.9	-3.0	-3.2	-3.1	-3.1	-3.3	-3.2	-2.1	-3.1	-3.1	-1.3	-2.7	-2.5	-2.0	-3.3	-3.0
Verbal and Numeric Reasoning (VNR)	5.2	12.4	18.5	3.4	3.4	3.6	3.7	3.8	3.5	3.8	3.6	-4.0	2.8	2.5	3.5	3.6	3.8	4.3	2.6	3.2	3.3	4.3	3.2	4.2	1.3	3.9	3.9
Body Mass Index (BMI) (2010)	5.2	7.2	11.8	2.9	2.9	2.7	2.8	3.0	2.8	3.0	2.2	-2.6	2.4	2.6	2.2	2.5	2.9	2.9	2.3	2.9	3.4	1.8	2.8	2.6	1.5	2.9	3.0
Smoking status: Previous	4.8	7.2	12.5	1.5	2.6	2.5	2.8	2.9	2.4	2.8	3.5	-3.3	1.4	2.6	3.4	2.6	2.7	3.3	2.8	2.6	1.3	3.1	2.5	3.5	0.3	2.7	2.5
Supplements: Fish oil (including cod liver oil)	4.5	5.9	10.9	0.4	2.5	3.0	3.2	2.4	2.7	2.7	2.4	-3.1	2.4	1.9	2.5	3.1	3.3	2.6	2.9	1.9	1.7	2.1	2.2	2.2	0.6	2.5	1.8
Suffer from ‘nerves’	4.0	6.2	13.0	2.1	2.9	1.9	2.6	2.4	2.9	2.8	2.4	-2.6	1.6	1.3	2.6	3.2	2.0	3.1	1.3	1.4	2.5	3.6	2.1	3.2	1.7	3.0	2.8
Trunk fat mass	3.9	16.9	38.9	6.2	3.6	4.8	3.5	3.8	3.4	4.3	4.2	-3.6	4.4	3.4	4.0	3.1	3.3	4.7	2.9	4.6	3.8	4.6	4.2	5.2	1.5	4.2	5.0
Weight	3.8	18.7	41.8	6.5	4.0	5.6	3.6	3.7	3.4	4.7	4.3	-3.7	4.1	3.5	4.3	3.2	3.4	4.9	3.1	4.6	4.2	5.0	4.2	5.6	1.4	4.4	5.5
Chronotype (morning person)	3.6	8.4	16.1	-2.6	-3.3	-2.2	-4.0	-3.3	-3.5	-3.2	-1.9	3.6	-2.7	-3.0	-2.5	-3.7	-4.0	-3.1	-3.0	-2.2	-1.4	-1.8	-3.1	-2.8	-0.6	-3.1	-2.4
Waist circumference	3.6	13.3	34.8	5.9	2.9	4.5	2.8	3.1	2.8	3.6	3.5	-3.2	3.2	3.2	3.3	2.2	2.6	4.1	2.8	4.4	3.6	3.9	3.7	5.0	0.8	3.8	5.1
Number of full brothers	3.6	4.6	6.9	1.6	2.1	1.7	2.4	2.2	2.3	2.3	1.8	-2.6	1.8	1.7	2.4	2.5	2.2	2.6	1.3	1.8	2.0	2.5	2.4	2.4	1.0	2.5	2.1
Whole body fat mass	3.6	15.2	35.0	5.9	3.4	4.7	3.1	3.6	3.1	4.2	3.9	-3.3	4.2	3.4	3.7	2.8	3.0	4.4	2.9	4.5	3.7	4.3	4.0	5.0	1.4	4.0	4.9
Townsend deprivation index at recruitment	3.5	4.9	10.4	2.7	1.8	2.5	2.1	2.3	2.1	2.3	3.2	-2.5	2.2	2.2	2.5	1.8	1.4	2.6	0.9	1.8	1.4	2.0	1.9	3.2	0.2	2.4	2.8
Pulse wave Arterial Stiffness index	3.5	4.1	7.1	1.5	1.5	2.0	2.2	2.0	2.1	2.0	2.2	-2.2	2.0	1.1	1.8	1.9	2.0	2.3	1.6	2.2	1.9	1.9	2.2	2.7	0.8	2.5	2.6
Tense / ‘highly strung’	3.5	5.8	10.0	1.3	2.7	0.9	2.4	2.7	2.8	2.9	2.1	-2.7	1.5	2.2	2.1	2.1	1.4	2.8	2.8	3.0	2.6	1.7	2.9	3.1	1.3	2.8	3.2
Health satisfaction	3.5	4.5	9.6	-1.2	-2.6	-1.7	-2.9	-2.9	-2.5	-2.4	-2.2	2.6	-2.3	-3.1	-2.2	-2.6	-2.2	-1.8	-2.6	-2.0	-0.8	-0.5	-1.6	-1.7	0.1	-1.7	-1.4
Leg fat mass (left)	3.5	13.8	29.3	5.4	3.3	4.7	3.0	3.5	3.0	4.0	3.7	-3.2	4.0	3.4	3.5	2.6	2.9	4.1	3.0	4.4	3.5	3.6	3.8	4.7	1.1	3.8	4.8
Hip circumference	3.4	14.7	36.8	6.1	3.6	5.2	3.0	3.3	3.0	4.0	3.3	-3.1	3.5	3.3	3.3	2.5	2.9	4.2	3.8	4.6	4.0	3.9	3.8	4.8	0.8	3.7	5.0
Pulse wave peak to peak time	3.4	4.0	6.7	-1.4	-1.5	-2.0	-2.2	-2.1	-2.2	-1.9	-2.0	2.2	-1.9	-1.3	-1.6	-1.9	-2.0	-2.2	-1.9	-2.4	-1.9	-1.6	-2.3	-2.6	-0.7	-2.5	-2.6
Arm fat mass (left)	3.3	13.5	32.1	5.7	3.3	4.6	2.9	3.2	2.9	3.9	3.5	-3.0	3.7	3.3	3.4	2.4	2.8	4.1	2.9	4.2	3.5	4.0	3.6	4.7	1.3	3.7	4.8
Serious illness, injury or assault to yourself	3.2	3.9	8.1	0.4	-2.5	-0.4	-2.3	-2.0	-2.4	-2.2	-2.6	1.5	-1.2	-2.4	-2.4	-2.9	-1.8	-1.7	-2.1	-1.9	-2.4	-0.3	-1.8	-0.5	-2.7	-2.1	-1.5
Arm fat mass (right)	3.2	13.1	32.4	5.7	3.2	4.6	2.8	3.2	2.8	3.9	3.5	-2.9	3.7	3.3	3.4	2.3	2.8	4.1	2.9	4.1	3.3	3.9	3.4	4.8	1.1	3.6	4.7
Family relationship satisfaction	3.2	4.0	8.5	-1.2	-2.9	-1.1	-2.5	-2.3	-2.8	-2.2	-1.7	2.0	-1.2	-2.7	-2.0	-2.3	-2.2	-1.6	-2.4	-2.2	-1.6	1.2	-1.6	-0.8	-1.6	-2.1	-1.5
Ever had bowel cancer screening	3.2	3.7	7.7	0.9	2.2	1.1	2.5	1.3	2.3	1.8	2.0	-2.3	1.6	1.3	1.8	2.8	2.3	1.8	1.3	1.7	1.7	2.1	2.0	1.7	2.3	2.4	1.6
Heel T-Score	3.1	24.9	231.0	-11.8	2.3	3.1	3.2	1.4	2.9	5.9	-0.5	-3.8	-4.4	5.7	-0.7	1.0	1.4	1.3	15.2	5.0	4.3	2.1	5.9	0.4	-0.2	1.5	0.9
Past tobacco smoking	3.1	5.7	15.1	-1.6	-2.0	-2.6	-2.2	-2.4	-2.0	-2.4	-3.9	2.7	-1.6	-2.2	-3.6	-2.3	-2.3	-2.9	-1.9	-1.8	-0.8	-3.2	-1.5	-3.2	-0.5	-2.3	-2.3
Leg fat mass (right)	3.1	12.2	27.7	5.3	2.9	4.5	2.7	3.2	2.6	3.7	3.5	-3.0	3.9	3.0	3.4	2.2	2.6	3.9	2.8	4.2	3.1	3.5	3.5	4.6	0.7	3.5	4.6
Eye problems/disorders: Diabetes related eye disease	3.0	3.3	6.8	-1.3	-2.6	-2.2	-2.4	-2.6	-2.0	-2.5	-2.3	1.8	-2.2	-2.6	-2.0	-2.1	-2.0	-1.5	-1.4	-1.2	-1.0	-0.7	-0.9	-1.2	0.0	-1.0	-1.0
Trunk fat percentage	3.0	12.0	32.0	5.7	2.8	3.6	2.7	3.1	2.8	3.5	3.5	-2.9	4.1	2.9	3.3	2.5	2.7	3.9	2.3	3.9	3.2	3.9	3.6	4.4	1.5	3.6	4.3
Fluid intelligence score	3.0	6.2	8.8	2.5	2.6	2.0	2.7	2.7	2.6	2.8	2.8	-2.6	1.6	1.6	2.8	2.9	2.6	2.9	1.6	1.9	2.3	3.0	2.3	2.7	1.8	2.9	2.8
Intelligence (Savage-Jansen 2018)	2.9	8.8	15.0	2.8	2.7	3.1	3.3	3.3	2.9	3.2	3.1	-3.7	1.5	1.9	2.9	3.0	3.2	3.7	1.6	2.6	3.0	3.7	2.7	3.9	0.3	3.0	3.5
Happiness	2.8	3.4	8.0	-1.7	-2.3	-1.4	-2.6	-2.7	-2.5	-2.1	-1.5	2.3	-1.5	-2.8	-1.5	-2.1	-2.2	-1.7	-2.1	-1.5	-0.8	-0.3	-1.8	-0.9	-0.5	-1.5	-0.5
Body fat percentage	2.8	11.0	27.1	5.2	2.6	3.6	2.5	3.0	2.6	3.3	3.5	-2.8	3.9	2.8	3.2	2.3	2.5	3.7	2.4	4.0	3.0	3.5	3.5	4.2	1.3	3.4	4.2
Supplements: Vitamin C	2.8	3.3	5.1	0.8	2.1	0.8	2.0	1.3	2.0	1.9	1.2	-1.9	1.9	1.4	1.8	2.0	2.2	2.0	1.8	1.9	2.2	1.2	2.3	1.5	2.1	2.2	1.8
Ever smoked	2.8	5.0	13.0	1.6	1.8	2.4	2.0	2.0	1.9	2.2	3.6	-2.2	2.0	1.8	3.4	2.4	2.4	2.6	1.6	1.3	1.2	3.2	1.4	2.6	1.3	2.3	2.0
Rheumatoid Arthritis	2.7	3.8	6.9	-1.2	-1.5	-2.2	-2.1	-2.1	-1.9	-1.9	-1.4	2.5	-1.2	-1.8	-1.3	-1.5	-2.0	-2.4	-1.8	-2.0	-2.0	-2.2	-2.6	-2.5	-0.2	-2.1	-2.5
Triglycerides	2.7	4.4	7.6	2.1	2.1	2.7	2.2	2.1	2.1	2.2	2.8	-2.1	2.3	1.8	2.4	2.3	1.9	2.3	1.3	2.0	2.0	1.9	1.6	2.3	0.7	2.1	2.4
BMI	2.7	15.9	28.6	5.3	3.8	4.7	2.9	3.8	3.8	4.5	4.0	-3.0	3.9	4.3	4.0	2.7	2.8	4.3	3.6	4.5	4.3	3.1	4.2	4.2	2.7	4.4	5.1
Diverticular disease/diverticulitis (self-reported)	2.7	3.2	8.9	1.4	1.4	1.4	1.2	1.6	1.6	1.9	1.7	-1.6	0.9	1.5	1.7	1.2	0.7	2.1	1.0	1.8	2.0	2.6	2.1	2.7	1.3	2.2	3.0
Leg fat percentage (left)	2.7	9.7	21.7	4.7	2.3	3.7	2.3	3.0	2.4	3.2	3.3	-2.8	3.2	2.9	2.9	1.9	2.3	3.4	2.4	4.1	2.8	2.8	3.5	4.1	0.8	3.3	4.3
Ever unenthusiastic/disinterested for a whole week	2.6	3.1	7.8	-1.5	-1.9	-1.3	-2.4	-1.8	-2.1	-1.7	-1.3	2.0	-2.4	-1.2	-1.7	-2.2	-2.8	-2.0	-1.0	-1.0	-1.1	-1.4	-1.5	-1.4	-1.6	-2.1	-1.3
Medication: Paracetamol	2.6	4.2	7.5	1.7	2.3	1.4	1.9	2.6	2.0	2.7	2.7	-1.9	0.7	2.3	2.7	1.8	1.6	2.5	1.1	1.7	1.8	2.4	2.0	2.5	1.2	1.9	2.2
Exposure to tobacco smoke outside home	2.6	3.5	8.4	2.9	1.7	2.5	1.2	1.5	1.9	1.9	2.6	-1.2	2.3	1.4	2.3	1.5	1.0	2.2	0.0	1.2	2.2	1.9	0.9	1.8	1.8	2.1	2.3
Reason for reducing amount of alcohol drunk: Health precaution	2.6	3.1	6.3	-1.7	-1.9	-2.2	-1.8	-2.5	-1.9	-2.1	-1.5	2.2	-1.1	-2.3	-1.3	-1.3	-1.4	-2.0	-1.6	-1.6	-1.9	-1.2	-1.5	-2.1	0.0	-1.6	-1.9
Heel bone mineral density (BMD) T-score, automated (right)	2.5	5.8	39.4	-4.6	1.8	2.1	2.2	0.8	1.4	3.3	0.4	-2.5	-1.1	2.3	0.1	1.2	1.6	1.1	6.3	3.1	2.0	1.8	3.5	1.0	-0.9	1.2	1.2
Birth weight of first child	2.5	4.6	8.0	-2.2	-2.8	-1.5	-2.8	-1.8	-2.4	-2.3	-1.4	2.6	-2.4	-1.7	-1.8	-2.5	-2.3	-2.2	-1.7	-2.5	-2.0	-1.7	-2.1	-2.2	-0.4	-2.3	-2.1
Guilty feelings	2.5	3.7	6.6	0.8	2.4	1.9	2.4	2.1	2.1	2.4	2.1	-2.0	2.4	1.2	2.5	2.6	2.4	2.4	0.8	0.6	0.7	2.1	0.9	2.3	0.1	2.0	1.7
Commuting to job workplace: Cycle	2.5	3.1	11.7	1.9	1.5	1.9	1.6	1.7	1.5	2.0	1.3	-1.9	1.1	1.5	1.8	1.2	1.6	2.3	1.4	1.0	1.6	3.4	2.0	2.1	0.5	1.6	1.7
Leg fat percentage (right)	2.4	8.6	21.6	4.7	2.0	3.6	2.1	2.9	2.0	3.0	3.2	-2.6	3.3	2.6	2.8	1.6	2.1	3.2	2.2	3.8	2.2	2.7	3.1	4.1	0.3	2.9	4.0
Pulse rate, automated reading	2.4	7.8	21.3	-0.3	-2.6	-3.0	-3.0	-2.8	-2.3	-3.4	-4.6	2.5	-3.2	-1.7	-4.5	-3.9	-2.5	-3.2	-1.5	-0.8	-1.6	-4.4	-1.2	-3.0	-1.1	-2.3	-1.8
Overall health rating	2.4	5.1	9.0	-1.2	-2.5	-1.9	-2.8	-2.3	-2.8	-2.3	-2.2	2.5	-2.2	-2.6	-2.0	-2.5	-3.0	-2.1	-2.3	-2.4	-2.5	-1.0	-2.9	-1.1	-1.9	-2.3	-1.5
Arm fat percentage (left)	2.4	9.6	25.2	5.0	2.5	3.6	2.3	2.7	2.4	3.1	2.9	-2.5	3.3	2.8	2.9	1.9	2.3	3.5	2.6	3.9	3.1	3.1	3.3	4.0	1.1	3.2	4.2
Number of operations (self-reported)	2.4	3.6	8.3	2.5	1.8	2.4	1.9	1.4	1.4	1.8	2.2	-2.2	2.2	1.4	1.9	1.3	1.9	1.9	0.9	2.1	1.8	1.8	1.3	2.9	-0.3	1.8	2.6
Body mass index (BMI)	2.3	9.7	23.5	4.8	2.4	4.0	2.2	2.8	2.3	3.2	3.1	-2.5	2.8	3.1	2.7	1.5	1.9	3.3	2.9	4.0	3.3	2.7	3.4	4.0	0.9	3.1	4.5
Arm fat percentage (right)	2.3	9.2	22.8	4.8	2.5	3.5	2.3	2.7	2.2	3.2	3.1	-2.5	3.5	2.8	3.0	1.9	2.2	3.4	2.5	3.6	2.7	3.0	2.8	4.1	0.9	3.0	4.0
Mouth/teeth dental problems: Bleeding gums	2.3	3.0	5.1	-0.5	-1.6	-1.7	-1.9	-2.2	-2.1	-2.1	-1.8	1.7	-0.1	-1.6	-1.6	-2.2	-2.1	-1.9	-1.6	-1.4	-2.2	-0.8	-1.9	-1.0	-1.1	-2.1	-1.8
Mineral and other dietary supplements	2.3	3.1	7.6	-0.4	-1.9	-2.8	-2.5	-1.9	-1.9	-2.0	-1.5	2.1	-1.3	-1.6	-1.8	-2.1	-2.7	-1.7	-1.8	-1.6	-1.2	-1.1	-1.4	-1.4	-0.4	-1.6	-1.1
Commuting to job workplace: Public transport	2.3	2.7	5.0	-0.5	-1.5	-1.7	-2.1	-1.4	-1.9	-1.5	-1.2	1.5	-1.4	-1.6	-2.2	-2.1	-1.9	-1.7	-2.2	-1.8	-1.6	-0.9	-1.2	-1.1	-1.7	-2.1	-1.4
Long-standing illness, disability or infirmity	2.2	3.4	6.0	-0.8	-2.4	-1.5	-2.4	-2.2	-2.4	-2.0	-2.1	2.1	-2.1	-2.5	-1.8	-2.2	-2.1	-1.6	-1.8	-1.7	-1.9	-0.0	-1.8	-0.7	-1.2	-1.7	-1.1
Basal metabolic rate	2.2	11.9	25.6	5.1	3.7	4.7	3.1	3.0	2.9	4.0	3.4	-2.7	3.1	2.9	3.6	2.8	2.8	3.9	2.4	3.4	3.3	3.6	3.0	4.2	1.1	3.5	4.3
Leg fat-free mass (left)	2.1	11.2	24.4	4.9	3.6	4.4	3.0	2.9	2.8	3.8	3.1	-2.6	2.9	2.8	3.4	2.7	2.8	3.8	2.5	3.4	3.4	3.5	2.9	4.1	1.2	3.4	4.2
Leg predicted mass (left)	2.1	11.0	24.6	5.0	3.6	4.3	3.0	2.8	2.8	3.7	3.0	-2.6	2.9	2.8	3.3	2.7	2.7	3.8	2.5	3.4	3.4	3.5	2.9	4.1	1.1	3.4	4.2
Number of incorrect matches in round	2.1	3.5	6.8	-1.4	-1.9	-2.0	-1.8	-2.1	-1.6	-2.6	-1.9	2.0	-2.2	-1.6	-1.9	-1.7	-1.6	-2.2	-1.4	-1.8	-1.6	-2.2	-1.8	-2.5	-0.1	-2.0	-2.0
Serious illness, injury or assault of a close relative in last 2 years	2.1	2.4	5.5	-0.5	-1.4	-1.5	-1.9	-1.7	-1.2	-1.9	-1.5	2.0	-2.2	-1.6	-1.5	-1.4	-1.1	-1.6	-2.2	-1.2	0.2	-1.7	-0.9	-2.4	1.3	-1.0	-1.0
Ever highly irritable/argumentative for 2 days	2.1	2.5	6.5	-1.1	-2.0	-1.9	-2.4	-2.2	-1.9	-1.9	-1.3	1.9	-1.2	-1.6	-1.6	-2.2	-2.5	-1.7	-1.4	-1.0	-0.2	-0.6	-0.7	-1.3	0.0	-1.5	-0.8
Ever had stillbirth, spontaneous miscarriage or termination	2.1	2.2	5.0	-1.7	-1.6	-0.8	-1.1	-1.0	-1.4	-1.6	-1.6	1.2	-2.1	-0.9	-2.0	-1.0	-0.6	-1.5	-1.7	-1.7	-1.0	-1.3	-1.2	-2.2	-0.9	-1.7	-2.2
Breast cancer (self-reported)	2.1	2.5	3.9	-0.7	-0.6	-1.2	-1.6	-1.8	-1.6	-1.3	-1.9	1.9	-1.7	-1.4	-1.9	-1.8	-1.2	-1.7	-0.7	-1.6	-1.9	-1.7	-1.9	-1.7	-1.0	-2.0	-1.9
Leg predicted mass (right)	2.1	11.5	22.8	4.8	3.8	4.3	3.2	2.8	3.1	3.8	3.0	-2.6	2.6	2.9	3.3	3.0	2.8	3.8	2.7	3.4	3.8	3.6	3.1	4.0	1.4	3.6	4.3
Myopia	2.1	3.0	7.6	-1.9	-1.0	-1.8	-2.4	-2.1	-1.9	-1.5	-1.1	2.8	-1.2	-1.7	-0.8	-1.2	-1.8	-1.9	-2.0	-2.1	-1.3	-0.7	-2.4	-2.2	1.1	-1.6	-1.6
Arm predicted mass (left)	2.1	10.9	24.3	4.9	3.7	4.8	2.9	3.0	2.8	4.0	3.3	-2.4	3.2	3.0	3.4	2.6	2.6	3.7	2.2	3.0	2.9	3.4	2.6	4.1	0.7	3.2	4.0
Leg fat-free mass (right)	2.0	10.8	22.2	4.7	3.7	4.2	3.0	2.7	2.9	3.7	2.9	-2.6	2.5	2.8	3.2	2.8	2.7	3.7	2.6	3.3	3.6	3.5	3.0	3.9	1.4	3.4	4.2
Irritability	2.0	3.3	8.4	0.7	2.0	0.5	1.4	1.4	1.6	2.2	1.9	-1.7	1.6	1.8	1.8	1.4	0.8	1.8	2.0	2.6	1.6	1.5	2.5	2.4	1.2	2.0	2.9
Fasting Glucose	1.9	2.3	6.5	-0.3	-1.6	-1.8	-2.0	-0.6	-1.3	-1.6	-2.2	1.7	-1.1	-0.4	-2.5	-2.0	-2.0	-1.7	-0.9	-1.4	-1.0	-1.4	-1.0	-1.7	-1.1	-1.5	-1.3
Average weekly spirits intake	1.9	2.4	7.6	2.4	1.5	1.2	1.2	1.3	1.6	1.4	-0.1	-1.5	1.1	1.6	0.1	0.6	1.4	1.6	2.0	2.0	1.5	1.4	2.8	1.5	1.2	1.4	1.9
Eye problems/disorders: None of the above	1.9	2.2	6.1	0.9	1.5	1.5	1.6	2.0	1.4	2.1	2.4	-1.1	2.5	1.1	2.1	1.7	1.1	1.6	-0.2	1.0	1.1	0.8	0.4	1.5	1.0	1.6	1.3
Wears glasses or contact lenses	1.9	2.2	5.7	-1.9	-1.7	-1.6	-1.6	-1.9	-1.7	-2.0	-0.4	1.5	-1.1	-2.4	-0.4	-0.7	-1.3	-1.5	-1.7	-1.3	-1.2	-1.6	-1.9	-1.5	0.0	-0.9	-1.3
Arm fat-free mass (left)	1.9	9.9	21.8	4.7	3.4	4.7	2.8	2.8	2.6	3.8	3.3	-2.3	2.9	2.8	3.4	2.5	2.5	3.6	2.0	2.7	2.6	3.4	2.4	3.9	0.6	3.0	3.8
Knee pain experienced in last month	1.8	2.7	8.8	3.0	1.5	1.8	1.2	1.8	1.4	1.8	1.3	-1.7	1.3	2.7	0.8	0.6	1.5	1.6	1.8	1.8	1.6	0.7	1.6	2.2	-0.2	1.3	1.9
Medication: Blood pressure	1.7	3.0	6.6	-0.6	-2.2	-1.5	-2.4	-2.5	-2.3	-1.9	-0.6	1.7	-1.4	-2.6	-1.0	-2.3	-2.5	-1.4	-1.3	-1.8	-1.8	-0.1	-2.0	-0.7	-0.6	-1.5	-1.3
Medication: Omeprazole	1.7	2.0	6.7	-0.5	-2.0	-1.2	-1.5	-1.9	-1.6	-1.8	-2.0	1.1	-2.6	-2.5	-1.7	-1.6	-1.2	-1.2	-1.7	-0.6	0.0	0.1	-0.2	-0.7	-0.5	-0.8	-0.2
Arm predicted mass (right)	1.7	8.7	21.5	4.6	3.1	4.3	2.5	2.6	2.4	3.4	2.9	-2.2	2.2	2.4	2.9	2.2	2.3	3.3	2.0	3.0	3.0	3.2	2.8	3.5	1.0	3.0	3.7
Chest pain or discomfort	1.7	2.4	7.7	-1.5	-2.1	-1.7	-1.7	-1.6	-1.8	-1.6	-0.8	1.1	-1.9	-2.1	-1.1	-1.4	-2.0	-1.1	-2.8	-2.0	-1.7	0.5	-1.0	-0.1	-1.1	-1.1	-0.7
Qualifications: NVQ or HND or HNC or equivalent	1.7	2.0	4.1	-0.9	-2.0	-1.6	-1.9	-1.6	-1.6	-1.6	-0.8	1.9	-1.2	-1.8	-1.1	-1.3	-1.8	-1.5	-1.6	-1.6	-0.9	0.2	-0.8	-1.5	0.4	-1.2	-1.5
Heel bone mineral density (BMD) T-score, automated (left)	1.6	3.7	31.1	-4.9	1.1	1.2	1.3	-0.1	0.7	2.3	-0.4	-1.5	-2.3	1.4	-0.5	0.5	0.7	0.3	5.6	2.1	1.0	1.1	2.4	0.3	-1.0	0.5	0.3
Arm fat-free mass (right)	1.6	8.3	19.9	4.5	3.0	4.3	2.5	2.4	2.3	3.3	2.6	-2.3	2.3	2.2	2.7	2.1	2.3	3.3	1.9	3.0	2.8	3.2	2.7	3.6	0.6	2.9	3.6
Whole body fat-free mass	1.6	9.1	19.8	4.5	3.4	4.3	2.7	2.6	2.5	3.5	3.0	-2.3	2.6	2.5	3.2	2.5	2.5	3.4	2.0	2.9	2.9	3.2	2.5	3.7	0.9	3.0	3.8
Whole body water mass	1.6	9.4	19.8	4.5	3.5	4.4	2.8	2.6	2.6	3.6	3.1	-2.3	2.6	2.5	3.2	2.6	2.5	3.5	2.0	2.9	2.9	3.2	2.5	3.7	0.9	3.1	3.8
Medication: Atorvastatin	1.6	2.0	7.2	1.2	2.0	1.4	1.5	0.8	1.2	1.5	2.0	-1.4	0.4	1.2	1.7	1.4	0.8	1.2	1.2	1.8	0.3	1.0	0.3	2.7	-0.2	1.5	2.1
Primary Biliary Cirrhosis	1.5	2.2	6.5	-1.7	-2.3	-0.9	-1.8	-1.3	-1.9	-2.0	-1.4	1.2	-2.5	-1.4	-1.6	-1.8	-1.4	-1.4	-0.9	-0.7	-1.1	-0.6	-1.0	-1.1	-1.1	-1.5	-1.3
Nervous feelings	1.5	2.8	7.1	1.4	2.0	1.1	1.9	1.8	1.8	2.2	2.2	-1.9	1.6	1.2	2.1	1.9	1.6	2.0	1.0	0.1	0.8	2.7	0.6	2.4	0.3	1.3	1.1
Number of live births	1.5	2.1	5.2	1.8	1.2	1.9	2.0	1.7	1.5	1.2	1.4	-2.2	0.8	2.0	1.2	1.4	2.3	1.7	1.1	1.0	1.0	0.7	1.4	1.2	-0.6	1.2	1.0
Hand grip strength (right)	1.4	3.8	8.5	-1.0	-2.1	-1.8	-2.0	-2.9	-2.3	-2.3	-2.0	2.1	-1.2	-2.6	-1.7	-2.0	-2.5	-2.4	-2.9	-1.9	-0.8	-1.1	-1.4	-1.7	0.1	-1.6	-1.2
Average weekly fortified wine intake	1.4	1.6	5.0	0.2	-1.3	-0.9	-1.4	-1.3	-1.4	-1.4	-2.1	1.1	-0.8	-0.5	-1.7	-2.2	-0.8	-1.4	-0.0	-0.5	-1.3	-1.2	-0.8	-1.1	-1.1	-1.5	-1.6
Alcohol usually taken with meals	1.4	2.3	8.1	-0.5	-1.6	-1.1	-1.6	-2.2	-1.5	-2.0	-2.8	1.4	-2.2	-2.1	-2.6	-1.8	-0.9	-1.5	-0.9	-0.6	-0.1	-0.8	-0.6	-1.4	-0.1	-1.0	-0.8
Trunk predicted mass	1.4	7.9	18.1	3.9	3.3	4.3	2.6	2.5	2.3	3.5	3.0	-2.2	2.5	2.4	3.1	2.4	2.4	3.3	1.8	2.4	2.3	2.9	2.1	3.5	0.5	2.8	3.3
Glaucoma (self-reported)	1.4	1.7	4.4	-0.2	-0.6	-1.2	-1.3	-1.2	-1.1	-1.1	-2.1	1.2	-0.4	-0.6	-1.6	-1.6	-1.3	-1.6	-0.1	-1.0	-1.0	-2.1	-0.9	-1.6	-1.6	-1.8	-1.6
Chronic bronchitis/emphysema (father)	1.3	1.6	2.7	-0.9	-1.4	-1.2	-1.2	-1.1	-1.6	-1.3	-0.7	1.0	-0.8	-0.8	-1.2	-1.3	-1.5	-1.4	-1.3	-1.4	-1.3	-1.4	-1.5	-0.7	-1.6	-1.6	-1.1
Trunk fat-free mass	1.3	7.7	17.8	3.9	3.2	4.2	2.6	2.5	2.3	3.4	3.0	-2.1	2.5	2.3	3.1	2.4	2.4	3.2	1.7	2.4	2.3	2.8	2.0	3.4	0.5	2.8	3.3
Pulse rate	1.3	2.3	9.4	-0.1	-1.0	-1.2	-1.6	-0.9	-1.0	-1.1	-3.1	1.3	-1.5	0.2	-2.5	-2.3	-1.8	-1.6	-0.9	-0.6	-1.3	-2.3	-0.8	-1.2	-1.6	-1.4	-0.8
Comparative body size at age 10	1.3	3.6	9.7	1.1	1.6	2.8	1.3	1.2	1.9	1.7	1.4	-1.4	0.2	2.0	1.5	1.3	1.6	1.7	2.8	2.9	3.1	1.4	2.4	0.9	2.3	2.3	2.0
Neck or shoulder pain in last month	1.3	1.8	5.9	-1.9	-0.7	-1.0	-1.2	-1.0	-1.1	-0.9	-0.8	1.5	-0.4	-1.0	-0.4	-0.8	-1.1	-1.3	-1.2	-1.7	-2.2	-1.4	-2.0	-1.7	-0.3	-1.5	-2.4
Eye problems/disorders: Cataract	1.3	1.5	4.5	-0.6	-1.0	-1.1	-1.4	-2.0	-1.1	-1.7	-1.1	1.3	-2.1	-1.2	-1.1	-1.2	-1.1	-1.3	0.6	-1.2	-1.3	0.1	-1.1	-1.0	-0.1	-1.2	-1.1
Mouth/teeth dental problems: Mouth ulcers	1.3	2.1	4.4	-2.1	-1.6	-0.9	-1.4	-0.8	-1.3	-1.3	-0.9	1.6	-1.7	-0.7	-1.3	-1.0	-1.2	-1.5	-0.9	-1.5	-1.7	-2.1	-2.0	-1.7	-0.7	-1.6	-1.9
Worry (Nagel 2018)	1.2	2.5	7.2	0.5	2.2	0.0	1.6	1.3	2.0	1.9	1.5	-1.9	0.3	0.9	1.2	1.7	0.8	1.7	1.5	1.3	1.3	1.8	1.6	2.7	0.9	1.9	2.1
LDL Cholesterol	1.2	1.9	4.8	-1.0	-1.2	-1.2	-1.3	-1.4	-1.8	-1.1	-0.8	1.3	0.1	-1.5	-1.4	-1.4	-1.6	-1.3	-0.5	-1.3	-2.0	-1.0	-1.8	-0.7	-2.2	-1.8	-1.0
Neuroticism (2016)	1.2	1.8	6.3	0.8	1.5	0.7	0.8	1.2	1.5	1.4	2.5	-0.4	1.5	0.7	2.1	1.7	0.4	1.1	0.1	0.4	1.4	1.7	0.6	0.9	2.3	1.4	1.2
Had menopause	1.2	1.4	5.8	1.3	0.7	0.7	1.1	0.9	1.1	1.0	1.3	-1.5	0.7	-0.1	0.9	1.2	1.2	1.4	0.9	1.0	0.9	2.4	1.1	1.7	1.1	1.5	1.2
Father’s age at death	1.2	1.6	4.1	-0.3	1.2	1.1	1.5	2.0	1.4	1.6	1.8	-1.6	1.0	0.8	1.6	1.6	1.2	1.7	1.3	0.8	0.3	0.9	0.9	1.3	-0.5	1.0	0.8
Frequency of tiredness / lethargy in last 2 weeks	1.2	1.9	4.5	-0.0	-1.2	-1.5	-1.5	-1.1	-1.3	-1.4	-2.1	1.5	-1.0	-1.0	-1.4	-1.4	-1.8	-1.2	-2.0	-1.6	-1.4	-0.7	-1.7	-0.8	-1.1	-1.4	-1.1
Comparative height size at age 10	1.2	6.8	15.8	2.5	2.8	3.3	2.7	2.1	2.4	2.7	3.0	-2.5	2.8	0.8	3.8	3.3	2.8	3.3	0.7	1.8	1.5	4.0	1.7	3.1	0.6	2.8	2.3
Osteoporosis (self-reported)	1.2	1.5	4.6	0.5	-1.1	-0.6	-1.3	-0.6	-1.2	-1.2	-0.7	1.4	-1.4	-0.8	-0.6	-1.1	-0.6	-1.5	-1.9	-0.7	-1.8	-2.1	-1.6	-1.6	0.3	-1.1	-1.3
Average weekly champagne plus white wine intake	1.2	1.6	6.9	-0.8	-1.2	-0.6	-1.5	-2.1	-1.4	-1.8	-1.6	1.1	-2.6	-2.2	-1.3	-1.4	-0.7	-1.0	-1.3	-0.1	-0.3	-0.6	-1.1	-0.6	-0.0	-0.6	-0.2
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	4.0	1.3	1.5	1.0	1.2	1.1	1.6	1.3	-0.2	-1.0	0.1	1.2	1.0	1.4	1.4	1.3	1.2	0.5	1.8	2.0	1.2	0.9	1.4	1.3	1.0
HbA1C	1.1	1.3	4.5	2.1	1.1	1.1	1.0	-0.0	0.7	1.5	0.9	-0.7	2.0	1.0	1.2	0.7	1.3	1.4	0.8	0.8	0.2	1.0	1.3	1.3	-0.9	0.4	1.1
Height	1.1	20.7	40.8	6.4	5.6	5.9	5.0	3.7	3.9	5.2	4.8	-4.1	5.2	2.5	5.5	5.1	5.2	5.3	1.6	2.9	2.7	6.4	2.5	5.5	0.1	4.1	3.6
Smoking Status	1.1	2.6	10.9	2.3	0.9	1.3	0.9	1.3	1.0	1.3	3.3	-1.3	1.6	1.0	3.0	1.5	1.1	1.8	0.1	0.6	0.6	2.3	0.7	1.8	1.3	1.6	1.5
Hand grip strength (left)	1.1	3.0	7.7	-0.4	-1.8	-2.0	-1.7	-2.7	-1.8	-2.3	-2.8	1.4	-1.0	-2.0	-2.6	-2.1	-2.1	-2.2	-1.8	-0.9	-0.1	-1.0	-0.0	-1.7	0.2	-1.3	-0.8
Sitting height	1.1	7.8	19.2	3.9	3.4	3.3	2.7	2.0	2.3	3.6	2.8	-1.9	4.0	1.5	3.3	3.0	2.8	3.2	2.1	1.3	2.2	4.4	1.9	2.6	1.7	2.5	1.9
Blood clot in the leg (DVT)	1.1	1.4	3.8	1.2	1.5	0.8	1.1	0.9	1.5	1.2	-0.3	-0.9	0.0	0.9	0.8	1.4	1.3	1.2	1.3	0.7	1.9	2.0	1.3	0.9	1.6	1.3	1.0
Number of full sisters	1.1	1.4	4.8	-0.1	1.5	0.7	1.7	1.7	1.7	1.1	1.8	-1.1	0.6	1.7	1.6	2.2	1.7	0.8	0.6	0.1	0.6	-0.5	0.4	-0.2	0.4	0.9	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.3	6.9	1.6	2.4	0.8	1.3	1.6	1.6	1.9	0.5	-1.1	1.7	2.0	0.7	1.0	0.9	1.0	2.1	2.6	1.4	-1.2	1.6	0.8	0.6	1.3	1.6
Ever depressed for a whole week	1.1	1.4	4.4	-0.8	-1.0	-1.1	-1.6	-1.5	-1.5	-1.0	-1.0	0.8	-2.1	-0.9	-1.1	-1.8	-1.8	-1.1	-0.4	0.2	-0.3	-1.1	-0.7	-0.3	-1.4	-1.4	-0.2
Bipolar Disorder (2011)	1.0	0.9	2.7	-0.5	0.8	0.5	0.8	0.6	0.9	0.7	1.3	-1.3	0.3	0.7	1.4	1.0	0.7	0.9	0.5	1.6	0.8	0.2	1.0	1.4	0.5	1.3	1.4
Schizophrenia (2014)	1.0	2.2	8.2	-0.6	0.5	0.8	1.5	1.8	0.9	1.1	2.9	-1.6	2.2	0.1	2.2	2.3	1.5	1.6	-0.9	-0.8	-0.9	2.4	-0.1	2.2	-0.4	0.9	0.1
Systolic Blood Pressure	1.0	5.1	8.9	-2.2	-2.2	-2.2	-2.6	-2.8	-2.2	-2.8	-0.9	2.7	-2.2	-2.8	-1.4	-1.8	-2.7	-2.5	-2.1	-2.2	-2.2	-2.5	-3.0	-2.1	-0.7	-1.8	-1.8
Vitamin and mineral supplements	1.0	1.4	4.7	-0.1	-1.8	-1.6	-1.2	-1.3	-1.2	-1.7	-0.9	0.8	-1.6	-1.3	-2.2	-1.3	-1.3	-1.2	-0.8	-0.7	-0.6	-0.3	0.1	-0.7	-0.9	-0.9	-0.4
Age when periods started (menarche)	1.0	2.4	5.7	-1.5	-1.5	-1.2	-1.6	-1.4	-1.9	-1.5	-2.1	1.3	-1.4	-1.0	-2.4	-1.7	-1.2	-1.8	-1.6	-1.2	-1.3	-1.2	-1.0	-1.5	-1.4	-1.9	-1.6
Chronic bronchitis/emphysema (mother)	1.0	1.1	7.6	-0.3	-1.1	-0.4	-1.0	-1.1	-1.0	-1.2	-0.7	0.9	-1.3	-1.3	-1.2	-0.7	-0.2	-0.6	-2.8	-1.3	-0.7	-0.1	-0.6	-1.2	0.7	-0.7	-1.1
Medication: Ibuprofen	1.0	1.2	3.7	0.3	-0.9	-0.2	-1.5	-0.9	-1.2	-0.9	-1.0	1.5	-0.8	-0.5	-0.9	-1.6	-0.9	-1.1	-1.9	-1.6	-0.2	-0.5	-1.5	-1.1	-0.0	-1.3	-0.9
Diastolic blood pressure, automated reading	1.0	3.2	11.7	0.7	-1.6	-1.6	-1.7	-2.1	-1.5	-2.4	-2.5	1.3	-1.8	-1.8	-3.0	-2.1	-1.4	-2.1	-1.6	-0.0	-0.8	-3.4	-0.6	-1.3	-1.8	-1.1	-0.4
Supplements: Calcium	1.0	1.1	4.8	0.9	0.7	1.1	1.0	0.2	0.7	0.3	1.4	-0.0	1.0	-0.7	2.1	1.5	1.4	0.8	-0.7	0.4	1.3	1.0	-0.2	0.1	2.2	1.0	0.3
Respiratory disease	0.9	2.1	8.2	0.6	1.0	0.7	1.6	1.8	1.2	1.6	2.3	-1.3	2.1	0.8	2.9	2.0	1.5	1.7	-0.0	0.5	0.8	1.0	0.7	1.5	0.4	1.4	1.4
Multivitamins +/- minerals	0.9	1.1	4.3	-0.0	1.3	2.0	1.1	1.4	1.1	1.4	1.2	-0.8	1.2	1.5	2.1	1.0	1.0	1.0	0.5	0.5	0.4	-0.0	-0.2	0.3	0.3	0.5	0.0
Financial difficulties in last 2 years	0.9	1.2	5.3	1.9	0.8	2.3	0.9	1.6	0.9	1.0	0.9	-1.3	0.7	1.2	1.1	0.4	0.8	1.2	0.0	0.9	1.1	0.2	0.8	1.1	-0.3	0.8	1.0
Alcohol intake versus 10 years previously	0.9	1.3	4.5	1.9	1.3	0.9	1.0	1.0	0.7	1.4	1.6	-1.1	2.1	0.9	1.6	0.9	0.9	1.4	-0.1	0.4	0.4	1.0	0.3	1.7	-0.3	0.7	1.3
Standing height	0.9	9.3	27.8	3.9	3.6	3.7	3.2	2.3	2.5	3.5	2.9	-2.7	3.2	1.1	3.7	3.5	3.1	3.8	0.5	1.5	2.0	5.3	2.0	3.7	1.0	3.0	2.5
Birth weight	0.9	1.9	3.9	1.4	1.5	2.0	1.2	1.4	1.0	1.5	1.0	-1.3	1.8	1.6	1.3	0.8	0.6	1.3	1.2	1.5	1.0	1.7	1.4	2.0	-0.1	1.1	1.7
Heart disease (mother)	0.9	1.1	2.8	0.4	1.4	0.5	1.1	1.1	1.2	1.2	1.0	-0.9	1.1	0.2	1.7	1.4	1.0	1.1	0.6	1.2	0.8	0.5	0.6	1.2	1.2	1.3	1.2
Asthma (self-reported)	0.9	1.7	4.3	1.4	0.7	1.3	1.1	1.6	0.8	1.5	1.9	-1.0	1.8	0.8	2.1	1.3	1.0	1.7	0.2	0.8	1.1	1.8	1.0	1.7	0.1	1.1	1.6
Medication: Gliclazide	0.9	1.0	2.8	1.1	1.7	-0.1	1.0	0.9	1.2	1.4	1.2	-0.6	1.2	1.1	1.2	1.2	0.8	1.1	0.9	0.3	-0.3	0.8	0.1	1.0	0.9	1.1	0.5
Illnesses of father: None of the above (group 1)	0.9	1.1	4.4	1.4	1.4	0.2	0.7	0.7	1.4	1.1	0.7	-0.3	0.9	0.7	0.8	1.3	1.1	1.1	0.9	0.7	1.3	1.0	1.2	0.5	2.1	1.4	0.9
Hearing aid user	0.9	1.0	3.7	-0.4	-1.0	-0.7	-1.1	-1.8	-1.1	-1.1	-1.9	0.8	-1.2	-1.9	-1.6	-1.3	-1.1	-0.6	0.4	0.4	-0.4	0.5	-0.3	-0.1	-0.3	-0.5	-0.0
Fractured/broken bones in last 5 years	0.9	1.1	5.6	1.9	-0.4	1.0	0.5	0.7	0.2	0.1	1.3	-0.5	-0.1	-0.6	1.6	0.6	1.0	1.2	-0.4	0.7	1.6	2.4	0.4	0.8	1.7	0.9	0.8
Bipolar Disorder (2018)	0.8	1.3	3.5	-0.4	1.6	1.1	1.4	0.4	1.1	1.2	1.4	-1.2	1.1	0.6	1.9	1.8	1.0	1.1	0.6	1.0	0.7	0.8	0.7	1.3	0.5	1.4	1.0
Prostate Cancer	0.8	1.1	5.8	1.3	0.9	0.8	0.7	-0.0	0.6	0.9	0.5	-0.9	-0.2	0.4	0.3	0.5	0.5	1.0	1.3	1.0	1.4	2.4	1.7	1.5	0.2	1.1	1.7
Allergy or Eczema	0.8	2.0	5.8	-1.1	1.6	0.5	1.6	1.5	1.6	1.5	2.4	-1.4	0.4	0.7	2.4	2.3	1.3	1.5	1.0	1.1	0.8	0.9	0.8	1.4	1.1	1.8	1.3
Lung FEV1/FVC ratio	0.8	3.8	10.6	-0.8	-2.1	-0.2	-3.0	-3.2	-2.7	-2.5	-1.2	2.5	-1.6	-2.7	-1.3	-2.5	-2.6	-2.1	-2.1	-1.1	-0.8	-0.7	-2.3	-1.3	-0.5	-1.8	-0.9
Neuroticism	0.8	2.0	4.8	0.9	2.0	0.1	1.2	1.1	1.7	1.6	1.4	-1.3	0.3	1.0	1.4	1.4	0.7	1.6	0.9	1.3	1.7	1.6	1.5	2.2	1.0	1.8	2.1
Maternal smoking around birth	0.8	1.1	4.8	-0.9	-0.1	-1.1	-1.0	-0.4	-0.6	-0.4	-0.2	1.2	-0.9	0.0	0.1	-0.5	-0.9	-1.0	-1.2	-1.7	-1.3	-2.0	-2.2	-1.1	-0.1	-0.9	-1.2
Hayfever, allergic rhinitis or eczema	0.8	1.8	4.4	-0.4	1.8	1.3	1.3	1.8	1.4	1.7	2.1	-0.9	0.6	1.5	2.0	1.7	1.4	1.5	1.4	1.1	1.1	0.6	0.5	0.7	0.9	1.3	1.0
Had other major operations	0.8	1.0	5.4	1.8	1.1	1.4	0.6	0.4	0.1	1.1	0.8	-0.6	2.3	0.7	0.7	-0.1	0.5	0.7	0.3	0.8	0.1	1.3	0.1	1.5	-1.1	0.1	1.1
Diabetes (self-reported)	0.8	1.3	4.4	1.8	1.7	1.2	1.0	1.2	1.2	1.8	0.6	-0.5	1.5	2.1	0.7	0.6	0.5	1.1	1.7	0.6	0.3	0.8	0.4	1.2	-0.3	0.7	0.7
Pulse wave reflection index	0.8	1.0	2.4	-0.1	0.4	0.8	1.1	0.5	0.9	0.5	1.3	-1.0	-0.1	-0.4	0.7	1.3	1.4	0.9	0.0	0.8	1.6	1.4	1.2	0.8	1.5	1.4	1.0
Medication: Seretide 50 evohaler	0.8	0.9	2.1	1.2	1.1	1.4	1.2	0.9	1.2	0.9	1.1	-0.8	1.2	0.9	0.9	1.1	1.0	1.2	-0.1	-0.0	0.7	1.3	0.4	0.9	0.0	0.8	0.6
Medication: Aspirin	0.8	1.1	3.1	0.8	0.7	0.9	0.9	0.6	1.1	0.8	1.2	-1.1	-0.2	-0.3	0.7	1.1	1.1	1.2	1.0	0.8	1.1	1.8	1.6	0.8	1.3	1.4	1.1
Hypertension (Self-reported)	0.8	2.2	5.5	0.4	-2.1	-0.5	-2.3	-2.0	-1.7	-1.5	0.2	1.8	-2.0	-2.0	0.1	-1.7	-2.3	-0.9	-1.6	-1.8	-1.2	0.5	-2.2	-0.4	-0.1	-0.7	-0.7
Medication: Aspirin	0.8	1.1	2.5	0.7	0.9	0.8	0.9	0.5	1.1	0.9	1.1	-1.1	0.2	-0.4	0.9	1.2	1.1	1.2	1.0	0.8	1.1	1.6	1.6	0.8	1.5	1.4	1.0
Eye problems/disorders: Glaucoma	0.8	0.9	2.5	0.1	-0.6	-0.6	-1.1	-1.0	-1.1	-0.7	-1.4	0.8	-0.3	-0.2	-1.2	-1.5	-1.1	-1.0	0.4	-0.7	-0.9	-1.0	-0.4	-0.7	-1.6	-1.4	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.8	0.9	2.8	0.3	-1.4	-0.7	-0.9	-1.4	-1.0	-1.1	-1.6	0.5	-1.7	-1.7	-1.2	-1.1	-0.9	-0.5	-1.0	0.1	0.8	0.8	0.6	0.1	0.0	-0.0	0.7
Alcohol drinker status: Previous	0.8	0.9	4.3	-0.8	-1.4	0.1	-0.9	-0.6	-1.1	-0.8	0.3	0.6	-0.6	-1.6	0.1	-0.6	-1.2	-0.5	-2.1	-0.8	-0.6	-0.9	-1.3	-0.7	-0.6	-0.6	-0.8
Bipolar Disorder or Schizophrenia	0.7	1.7	5.4	-0.5	1.0	0.8	1.6	1.2	0.9	1.1	2.3	-1.5	1.6	0.2	2.2	2.1	1.2	1.5	-0.3	-0.2	-0.3	1.8	0.3	2.0	0.0	1.1	0.4
Type 2 Diabetes (T2D) (2012)	0.7	0.8	1.9	1.2	0.6	1.0	0.9	0.8	0.6	0.8	-0.1	-1.3	-0.0	1.1	-0.2	0.3	0.7	0.8	1.3	1.1	0.3	1.1	1.1	1.2	-1.4	0.3	0.6
Lung FVC	0.7	3.7	12.3	-2.0	-1.2	-2.5	-1.4	-1.7	-1.4	-1.8	-3.5	1.2	-2.0	-0.6	-3.0	-2.2	-1.3	-2.4	0.2	-0.3	-1.4	-3.2	-0.7	-2.2	-0.8	-1.8	-2.1
Severe depression (siblings)	0.7	0.8	3.3	0.9	0.1	1.6	1.0	0.8	0.5	0.1	-0.1	-1.5	-0.1	1.2	-0.3	0.1	0.7	0.5	0.7	1.3	0.5	0.1	0.9	1.3	-1.8	0.4	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	2.3	0.8	-0.8	-1.0	-1.0	-1.4	-0.9	-1.2	-1.5	1.0	-0.5	-0.5	-1.4	-1.3	-1.2	-1.0	0.2	-0.7	-0.7	0.1	-0.3	-0.4	-1.2	-0.9	-0.8
Stomach or abdominal pain in last month	0.7	0.9	4.0	1.3	0.7	1.2	0.2	0.9	0.2	1.1	0.7	-0.5	0.2	0.9	0.7	-0.1	-0.0	1.1	1.2	0.8	-0.0	2.0	0.5	1.9	-1.3	0.2	1.1
Allergy	0.7	1.7	4.2	-0.5	-1.4	-1.0	-1.2	-1.8	-1.2	-1.7	-1.8	1.0	-0.9	-1.4	-2.1	-1.5	-1.1	-1.6	-1.1	-1.3	-1.3	-1.0	-0.7	-1.2	-0.2	-1.2	-1.5
Neuroticism score	0.7	1.4	3.3	0.8	1.5	0.3	1.1	0.9	1.5	1.3	1.2	-1.1	0.4	0.8	1.3	1.3	0.6	1.4	0.8	0.9	1.4	1.5	0.9	1.8	0.9	1.6	1.8
Asthma	0.7	1.4	3.1	1.2	0.4	1.1	0.9	1.4	0.6	1.3	1.6	-1.0	1.6	0.5	1.8	1.1	0.8	1.6	-0.0	0.8	1.1	1.7	1.1	1.8	-0.0	1.1	1.7
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	3.3	0.0	-0.9	-0.1	-1.4	-0.8	-1.1	-0.8	-0.9	1.4	-0.8	-0.3	-0.7	-1.5	-0.9	-0.9	-1.8	-1.3	-0.0	-0.3	-1.3	-1.0	-0.0	-1.1	-0.8
Loud music exposure frequency	0.7	0.8	3.4	0.3	0.2	1.9	0.4	1.0	0.4	0.8	1.0	-0.7	1.3	0.9	1.7	0.5	0.4	1.0	0.2	0.7	1.0	1.0	0.2	1.1	0.5	0.7	0.7
Medication for pain relief, constipation, heartburn	0.7	1.1	3.5	-1.2	-0.7	-0.7	-0.5	-1.1	-0.6	-1.1	-1.8	0.9	0.5	-0.6	-1.4	-0.5	-0.7	-1.2	0.2	-0.7	-1.2	-1.9	-1.2	-1.6	-0.4	-1.0	-1.6
Average weekly red wine intake	0.7	1.0	3.0	-1.2	-1.3	0.3	-1.2	-0.9	-1.0	-1.3	-0.5	1.4	-1.6	-0.3	-1.0	-1.0	-0.8	-1.2	-0.6	0.0	-0.5	-1.3	-0.9	-1.7	0.4	-0.7	-0.9
Mood swings	0.7	1.2	3.2	0.6	1.3	0.8	0.8	1.0	1.0	1.6	0.9	-1.0	1.1	1.4	1.4	0.9	0.3	1.2	0.8	1.2	1.2	1.0	0.7	1.6	0.3	1.2	1.8
Medication: Lisinopril	0.7	0.9	3.8	0.5	-1.3	-0.8	-1.2	-1.3	-1.2	-1.4	-0.3	1.0	0.1	-1.9	-0.5	-0.9	-0.9	-0.6	-1.4	-0.8	-0.8	0.0	-0.9	-0.8	-0.2	-0.6	-0.5
Basal cell carcinoma (self-reported)	0.7	0.9	2.5	-0.3	-1.0	-0.6	-1.3	-0.8	-1.2	-0.5	-1.4	0.8	-1.2	-0.9	-0.9	-1.6	-1.3	-0.7	-0.0	-0.3	-1.3	0.3	-0.2	-0.1	-1.3	-1.0	-0.2
Pack years of smoking	0.7	1.0	2.3	0.6	-1.3	-1.4	-1.2	-1.3	-1.1	-1.0	-0.4	1.3	1.0	-1.4	-0.5	-0.8	-1.5	-0.8	-1.0	-1.4	-0.5	-0.3	-0.7	-0.7	0.4	-1.0	-0.7
Depression (Nagel 2018)	0.6	1.0	3.7	0.8	-0.8	-0.7	-1.1	-1.9	-1.0	-1.3	-1.1	1.1	-0.3	-1.5	-0.9	-1.0	-1.4	-0.8	-0.3	-1.2	-0.3	0.9	-0.7	-0.2	-0.8	-0.7	-0.8
Hearing difficulty/problems: Yes	0.6	0.8	1.9	0.4	-1.0	-1.0	-1.2	-1.0	-1.4	-1.0	-1.2	0.8	-0.5	-0.8	-1.1	-1.3	-1.2	-1.1	-0.1	0.4	-0.8	-0.4	-0.7	-0.6	-0.7	-1.1	-0.7
Pack years adult smoking proportion	0.6	0.9	2.4	1.1	-1.1	-0.9	-1.2	-1.0	-1.0	-0.7	-0.5	1.3	1.2	-1.1	-0.4	-0.9	-1.4	-0.6	-1.1	-1.6	-0.5	-0.0	-0.8	-0.6	0.2	-1.0	-0.6
Taking other prescription medications	0.6	0.9	2.1	-0.6	-1.2	-1.5	-0.5	-1.0	-1.2	-1.2	-0.7	0.5	-0.3	-1.5	-0.8	-0.4	-0.7	-1.1	-1.3	-1.0	-1.2	-0.5	-0.7	-0.4	-0.8	-1.0	-0.9
High blood pressure	0.6	1.8	4.8	0.8	-2.0	-0.1	-2.2	-1.8	-1.7	-1.4	0.4	1.6	-1.6	-1.6	0.1	-1.7	-2.1	-0.7	-1.4	-1.4	-1.1	0.5	-2.0	-0.2	-0.4	-0.7	-0.5
Medication: Ramipril	0.6	0.7	1.8	-0.1	-0.8	-1.0	-1.2	-0.9	-1.0	-0.8	-0.7	1.0	0.3	-1.1	-0.2	-0.8	-1.3	-0.4	-1.1	-1.0	-1.2	-0.2	-0.9	-0.4	-0.5	-0.6	-0.7
Medication: Ventolin 100micrograms inhaler	0.6	0.7	2.2	-0.2	-0.9	-1.5	-0.4	-0.9	-0.6	-1.1	-0.9	0.5	0.3	-0.6	-0.8	-0.6	-0.8	-1.0	-0.9	-0.7	-1.0	-1.4	-1.0	-0.7	-0.6	-0.8	-0.9
Wheeze or whistling in the chest in last year	0.6	1.1	4.6	1.8	0.6	0.8	0.5	0.7	0.6	0.9	1.1	0.3	0.8	0.3	1.9	1.2	0.5	1.0	-1.0	0.0	1.1	1.6	0.1	0.4	2.1	1.0	1.0
Risk taking	0.6	0.9	2.9	0.3	0.8	0.6	0.7	1.7	0.4	1.5	0.8	-1.1	1.3	1.3	0.6	0.3	0.3	1.2	0.1	0.7	-0.6	0.9	0.7	1.6	-1.5	0.4	0.6
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.9	0.4	0.4	-0.0	0.8	0.8	0.8	0.6	0.7	-1.2	0.8	1.2	0.9	0.4	0.4	0.7	1.4	1.2	0.2	-0.2	1.1	1.0	-0.2	0.9	1.1
Neuroticism (Nagel 2018)	0.5	1.1	3.6	0.8	1.5	-0.1	0.6	0.2	1.0	1.1	1.6	-0.9	0.6	0.4	1.3	0.9	0.1	0.9	0.8	0.9	0.8	1.1	1.0	1.9	0.7	1.1	1.7
Alzheimer’s Disease (in father)	0.5	0.5	2.6	-0.7	-0.8	-1.3	-0.3	-0.5	-0.1	-0.7	0.1	0.4	-0.7	-1.2	0.2	0.3	0.0	-0.4	-1.2	-0.5	0.2	-0.9	0.0	-0.9	1.6	0.3	-0.3
Crohns Disease (2012)	0.5	0.7	3.4	-0.7	-0.8	-1.0	-1.0	-1.4	-0.7	-0.8	-0.5	0.7	-1.4	-1.8	-0.5	-0.4	-1.1	-0.8	-1.4	-0.5	0.3	0.0	-0.3	-0.1	-0.0	-0.2	0.5
Blood Eosinophil Count	0.5	3.6	13.3	0.4	1.7	1.6	2.4	2.2	1.5	2.3	2.6	-1.7	1.1	0.7	2.9	2.8	2.4	2.5	0.8	0.5	1.2	3.6	1.1	1.4	1.1	1.4	0.5
Type 2 Diabetes (T2D) (2018)	0.5	1.0	3.6	1.4	0.9	1.2	0.3	1.2	0.8	1.5	1.2	-0.3	1.4	1.6	0.9	0.4	0.0	1.2	0.9	-0.0	0.1	1.9	0.4	1.2	0.3	0.7	0.7
Supplements: Glucosamine	0.5	0.6	3.6	0.4	-0.5	-0.1	-0.3	-0.4	-0.7	-0.5	-1.9	0.1	-0.7	-0.2	-1.3	-1.3	0.0	-0.7	0.6	0.7	-0.6	-1.0	0.3	-0.7	-1.4	-0.9	-0.6
Medication: Atenolol	0.5	0.6	1.9	1.1	0.3	1.1	0.8	-0.0	0.6	0.2	1.0	-0.7	0.1	0.1	0.7	0.5	0.5	0.6	0.9	0.4	1.4	1.3	0.6	0.4	1.0	0.8	0.6
Heart attack	0.5	0.6	1.7	0.8	1.2	0.1	1.0	0.8	1.0	0.9	0.2	-1.3	0.5	1.1	0.2	0.8	1.0	0.7	0.8	0.4	0.5	0.6	1.3	0.8	-0.1	0.6	0.3
Time employed in main current job	0.5	0.6	2.2	-1.0	-0.0	-0.3	-0.4	-1.0	-0.5	-0.3	0.5	1.2	-0.4	-1.0	0.8	0.2	-0.3	-0.6	-1.0	-1.3	-1.0	-0.1	-1.5	-0.8	0.5	-0.4	-0.8
Mouth/teeth dental problems: Dentures	0.5	0.8	2.1	1.0	1.0	0.7	1.3	0.5	1.2	0.6	1.4	-1.2	1.1	0.4	0.8	1.3	0.8	0.6	0.2	0.5	0.4	0.3	1.0	0.5	1.1	1.2	1.1
Medication: Lansoprazole	0.5	0.6	1.4	1.0	-0.9	-0.8	-0.6	-0.5	-0.9	-0.5	-0.8	0.2	-0.9	-0.7	-1.2	-1.1	-0.7	-0.5	-0.3	-0.8	-0.9	0.3	-0.1	0.5	-1.2	-0.9	-0.5
Prospective memory result	0.5	0.6	2.4	-1.4	-0.1	-0.6	0.7	-0.3	0.4	-0.3	1.5	-0.7	0.5	-0.6	1.6	1.5	0.5	0.4	-0.5	0.1	0.1	0.1	0.3	1.0	0.4	1.1	0.8
Leg pain on walking	0.5	0.6	2.3	1.3	1.1	1.2	0.4	0.6	0.9	0.8	0.9	-0.3	1.2	1.5	0.5	0.3	0.1	0.4	0.6	0.6	0.5	-0.0	0.4	0.8	0.4	0.6	0.9
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	3.1	0.0	0.7	0.2	0.8	0.3	0.8	0.5	0.8	-0.2	1.6	0.6	0.5	0.9	0.6	0.4	1.8	0.6	0.6	0.8	0.6	-0.1	1.5	0.5	-0.0
Illnesses of father: Heart disease	0.5	0.7	2.9	0.2	-1.2	-0.4	-0.8	-1.0	-1.0	-1.2	-1.0	0.1	-0.4	-0.7	-1.1	-1.7	-0.8	-1.2	-0.1	0.0	-0.7	-0.5	0.4	-0.7	-1.1	-1.0	-0.7
Handedness (chirality/laterality): Left-handed	0.5	0.5	1.9	-0.5	-1.0	0.3	-0.7	-0.7	-0.9	-0.7	-0.0	0.6	1.0	-0.8	0.2	-0.9	-0.7	-0.4	-0.2	-0.6	-0.6	-0.8	-1.4	-0.1	-1.4	-0.6	-0.3
Loneliness, isolation	0.5	0.6	3.5	0.6	-0.9	-0.0	-0.8	-0.8	-0.9	-0.7	-1.0	0.4	-0.6	-0.1	-0.6	-1.2	-1.0	-0.7	0.1	-0.3	-0.6	-0.5	-1.0	-0.1	-1.9	-1.0	-0.7
Friendships satisfaction	0.5	0.7	3.1	-1.0	-1.3	-0.1	-0.7	-0.9	-1.3	-1.0	-0.4	0.5	-0.6	-1.6	-0.4	-0.6	-0.2	-0.2	-0.7	-0.2	-0.4	1.8	-0.6	-0.0	-0.5	-0.5	-0.5
Ever taken oral contraceptive pill	0.5	0.5	1.6	0.4	0.7	0.9	0.5	0.6	0.3	0.5	1.3	-0.3	1.2	0.8	1.2	0.7	0.1	0.6	-0.3	0.6	0.2	1.2	0.1	1.1	0.2	0.3	0.8
Medication: Blood pressure	0.5	0.9	4.6	1.5	0.4	1.3	0.3	0.3	0.8	0.6	2.1	-0.3	-0.2	0.2	2.0	1.0	0.4	0.9	-0.3	-0.3	0.4	1.4	-0.1	0.7	0.5	1.1	0.8
Illnesses of father: High blood pressure	0.5	0.6	2.5	-1.4	-0.4	0.9	-0.4	-0.2	-0.7	0.0	0.4	0.5	-0.4	-0.2	1.0	-0.0	-0.8	-0.1	-0.7	-1.4	-1.3	0.7	-1.6	0.1	-1.1	-0.7	-0.8
Average weekly beer plus cider intake	0.5	0.7	2.1	-0.3	0.8	1.0	0.9	1.5	0.7	1.2	1.1	-0.9	1.1	1.3	0.8	0.8	0.7	1.0	0.6	0.2	0.3	1.2	0.5	1.0	0.1	0.4	0.2
Schizophrenia (2018)	0.4	0.9	3.6	-0.4	-0.0	0.2	0.9	1.2	0.3	0.5	1.9	-0.9	1.2	-0.2	1.3	1.3	0.7	0.9	-0.8	-1.0	-1.0	1.7	-0.3	1.6	-0.4	0.3	-0.3
Alzheimer’s Disease (in mother)	0.4	0.4	3.3	-0.5	0.4	-0.2	0.3	0.0	0.7	0.2	1.3	0.0	-0.1	0.1	0.8	1.1	-0.0	0.3	0.0	-0.3	0.3	1.4	0.1	-0.1	1.8	0.5	-0.2
Alzheimer’s Disease (including proxy)	0.4	0.6	6.5	-0.7	0.2	-0.9	0.2	0.1	0.8	-0.1	1.1	0.2	-0.1	-0.5	0.8	1.3	0.3	0.2	-0.7	-0.4	0.3	0.6	0.4	-0.8	2.5	0.7	0.0
Blood Red Count	0.4	3.9	13.6	0.6	-1.8	-2.4	-1.7	-1.0	-1.6	-2.0	-3.2	1.4	-0.3	-0.8	-3.7	-2.7	-2.2	-2.2	-1.6	-0.4	-1.7	-3.6	-0.7	-1.6	-1.9	-1.9	-1.0
Number of treatments/medications taken	0.4	0.7	2.0	-0.4	-0.8	-0.7	-0.6	-1.1	-1.2	-0.7	0.2	0.4	-0.9	-1.1	-0.0	-0.6	-0.8	-0.8	-0.6	-1.1	-1.3	0.0	-1.0	0.0	-1.4	-1.1	-0.8
Ever used hormone-replacement therapy (HRT)	0.4	0.5	3.3	0.6	-0.3	-0.4	-0.1	-0.8	0.2	-1.1	-0.3	0.0	-0.9	-1.0	-0.5	0.2	0.2	-0.6	0.7	0.9	0.9	-0.2	0.2	-0.6	1.8	0.6	0.4
Diabetes (father)	0.4	0.5	4.8	0.6	-0.4	0.6	0.2	-0.1	-0.4	0.1	-1.3	-0.6	-0.5	0.1	-1.0	-0.8	-0.1	0.2	0.3	0.7	-0.4	0.1	0.8	0.9	-2.2	-0.3	0.3
Current tobacco smoking	0.4	0.7	2.5	1.5	-0.9	0.1	-0.7	-0.3	-0.4	-0.3	1.4	0.8	1.2	-0.1	0.9	-0.2	-0.7	-0.2	-1.6	-1.5	-0.4	0.7	-0.9	-0.1	0.8	-0.1	-0.1
Relative age voice broke	0.4	0.6	2.8	0.8	0.9	0.8	0.6	0.3	0.3	0.8	0.8	-0.5	0.7	0.7	0.9	0.5	0.5	0.9	0.5	0.1	0.4	1.7	0.5	1.5	-0.3	0.4	1.0
Hearing difficulty/problems with background noise	0.4	0.7	4.7	0.7	-0.1	0.6	-0.4	-0.3	-0.7	0.1	-0.5	-0.4	-0.5	-0.2	-0.7	-1.3	-0.3	0.1	1.4	1.4	-0.3	0.4	0.4	1.4	-2.2	-0.3	1.0
Hair/balding pattern: Pattern 2	0.4	0.5	2.5	0.0	-0.4	-0.1	0.2	-0.2	-0.1	-0.5	-0.4	-0.5	-1.5	-1.4	0.0	0.3	0.3	0.3	-1.6	-0.8	-0.6	1.0	0.3	1.0	-0.6	0.3	0.6
Qualifications: None of the above	0.4	0.9	3.3	1.8	1.1	0.9	1.1	0.9	1.0	1.0	0.8	-0.6	1.1	1.4	0.9	0.9	0.7	0.7	1.0	0.8	0.5	0.1	0.5	1.0	0.2	1.0	1.1
Pain all over the body in last month	0.4	0.4	1.5	-0.1	0.2	0.6	-0.4	-0.2	-0.2	-0.2	-0.6	0.7	-0.5	0.9	-1.1	-0.9	-0.6	-0.8	0.6	-0.2	-1.2	-0.8	-0.8	-0.6	-0.6	-0.7	-0.9
Noisy workplace	0.4	0.4	1.4	-0.2	-0.8	-0.6	-0.7	-0.9	-0.5	-1.2	-0.6	0.1	-0.3	-0.6	-1.2	-0.9	-0.8	-0.8	-0.2	0.6	-0.2	-1.1	0.3	-0.4	-0.5	-0.3	-0.0
Lung cancer (father)	0.4	0.4	2.1	0.7	-0.0	-0.4	0.2	0.6	0.1	0.4	1.4	-0.1	0.7	0.2	0.7	0.5	0.3	0.5	-1.2	-0.8	-0.4	1.4	-0.1	0.3	0.9	0.1	-0.3
Illnesses of mother	0.4	0.4	2.6	-0.4	-0.8	-0.3	-0.6	-0.2	-0.9	-0.6	-0.7	0.1	-0.5	-0.2	-1.1	-0.9	-0.9	-0.7	0.1	0.2	-0.5	-0.4	-0.2	-0.1	-1.6	-0.9	-0.2
Exposure to tobacco smoke at home	0.4	0.4	1.4	0.9	-0.5	0.3	-0.1	-0.1	0.0	-0.2	-0.1	-0.7	-1.0	0.1	-0.8	-0.5	-0.5	0.2	-0.3	1.1	1.2	0.3	1.1	0.8	-0.6	0.5	1.1
Headache pain in last month	0.4	0.8	2.9	0.4	0.4	0.4	0.3	0.8	0.2	1.0	1.0	-0.5	-0.4	1.1	1.2	0.4	-0.3	1.1	0.7	0.7	0.7	1.6	0.9	1.7	-0.3	0.6	1.5
Medication: Amlodipine	0.4	0.5	1.8	0.6	-0.5	-0.2	-1.2	-1.3	-0.6	-0.6	0.4	1.0	-0.9	-0.9	-0.0	-0.5	-1.2	-0.4	-0.4	-0.4	-0.1	0.5	-0.9	0.4	0.7	0.0	0.7
Worry too long after embarrassment	0.4	0.7	2.5	-0.2	-1.4	-1.6	-0.9	-1.0	-0.7	-1.4	-0.8	0.6	-1.4	-1.2	-1.1	-0.7	-0.9	-0.6	-1.0	-0.3	-0.1	0.0	0.4	-0.4	0.2	0.1	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	3.0	-0.2	-0.1	0.1	0.5	0.3	0.1	0.3	0.9	-1.0	-0.1	-0.5	0.7	0.5	-0.3	0.7	0.2	0.5	0.2	0.9	1.0	1.6	-1.7	0.4	1.1
Mouth/teeth dental problems: Loose teeth	0.4	0.5	3.3	0.3	-0.5	-0.4	-0.2	-1.1	-0.7	-0.7	-0.7	-0.4	-0.2	-1.4	-0.2	-0.3	-0.6	-0.1	0.8	0.2	-0.8	0.6	-0.1	0.9	-1.8	-0.1	0.3
Medication: Allopurinol	0.4	0.5	2.3	0.6	0.1	1.1	0.1	-0.1	-0.2	0.3	0.5	-0.7	0.6	0.2	0.4	-0.0	0.2	0.7	0.4	0.3	0.2	1.5	0.6	1.5	-0.9	0.4	1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	2.2	-0.6	-0.3	-1.2	-0.2	-0.2	-0.4	-0.8	0.2	0.4	0.2	-0.2	0.5	0.1	0.0	-0.6	-1.3	-0.5	-0.9	-1.5	-0.5	-0.7	-0.5	-0.4	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	1.7	-0.2	-1.0	-1.2	-0.5	-0.9	-0.6	-0.8	-0.5	0.1	-0.3	-1.3	-0.8	-0.4	-0.3	-0.2	-1.3	-0.3	0.4	0.6	0.5	-0.0	0.4	-0.0	0.1
Smoking status: Current	0.4	0.6	2.6	1.3	-0.8	0.2	-0.7	-0.3	-0.3	-0.3	1.6	0.7	1.1	-0.1	1.0	-0.1	-0.7	-0.2	-1.5	-1.4	-0.3	0.7	-0.9	-0.0	0.9	-0.0	0.0
High cholesterol (Self-reported)	0.4	0.8	3.1	1.3	0.5	0.2	0.3	-0.2	0.6	0.2	1.8	-0.1	0.5	-0.4	1.0	1.0	0.4	0.8	-0.1	0.1	0.5	1.2	0.1	1.1	1.7	1.3	1.2
Alcohol drinker status: Never	0.4	0.5	1.8	-0.9	0.2	-1.0	0.6	-0.0	0.8	-0.0	0.9	-0.7	-0.7	0.5	0.7	0.9	0.5	-0.0	1.4	0.5	0.2	-0.8	0.6	-0.2	1.2	0.8	-0.2
Vascular/heart problems diagnosed by doctor	0.4	1.0	2.3	-1.0	1.4	0.1	1.5	1.4	1.1	0.9	-0.6	-0.8	1.5	1.4	-0.3	1.1	1.5	0.2	1.2	1.2	0.9	-1.0	1.2	-0.4	0.4	0.2	0.0
Major Depression (MDD)	0.3	0.3	1.9	0.2	-0.2	0.3	-0.6	-0.2	-0.2	-0.3	-0.4	0.7	-0.4	0.4	-0.8	-0.3	-0.2	-0.1	-1.4	-0.8	-0.2	0.1	0.3	-0.7	1.3	-0.2	-0.2
Age at First Birth	0.3	0.5	3.6	-0.3	0.7	-0.7	0.8	0.5	0.6	0.5	0.7	-0.3	0.3	0.2	0.7	1.5	1.0	0.3	-0.6	-0.0	0.2	0.3	-0.0	-0.5	1.9	0.7	-0.3
Coronary Artery Disease (CAD)	0.3	0.3	1.1	1.0	0.7	0.1	0.8	0.0	0.5	0.4	-0.2	-0.9	1.0	0.4	-0.2	0.5	0.3	0.1	0.7	0.6	0.5	0.6	0.5	0.5	-0.5	0.0	-0.1
Ulcerative Colitis	0.3	0.4	2.2	-1.1	-0.3	-0.6	-0.1	-0.0	-0.3	-0.4	-0.2	-0.6	-1.0	-0.3	-0.3	-0.2	-0.6	-0.5	0.5	0.6	-0.8	-1.0	0.2	0.4	-1.5	-0.4	0.2
Ever had hysterectomy (womb removed)	0.3	0.4	2.0	1.2	-0.2	0.3	0.2	-0.6	-0.2	-0.2	-0.1	-0.4	-0.3	-0.2	-0.8	-0.2	-0.1	-0.2	0.3	0.0	-0.5	1.4	0.3	1.0	-1.4	0.1	0.3
Angina	0.3	0.3	1.7	-0.9	-0.2	-0.9	-0.1	-0.6	0.0	-0.3	0.4	0.2	-1.1	-1.3	0.5	0.5	-0.3	0.0	-0.6	-0.8	-0.5	0.4	-0.3	0.1	0.6	0.2	-0.3
Medication for hormone replacement therapy	0.3	0.3	3.0	-0.6	-0.1	-0.3	-0.0	0.1	-0.0	-0.5	-0.6	0.0	-1.2	0.4	-0.9	-0.1	0.2	-0.7	0.1	0.2	0.2	-1.7	-0.0	-0.9	-0.2	-0.2	-0.4
Medication: Co-codamol	0.3	0.4	1.4	-0.0	0.4	0.0	0.6	-0.5	0.5	0.1	0.7	-0.1	-0.3	-0.5	1.0	1.2	0.5	0.6	-0.5	-0.5	0.2	1.1	0.3	-0.1	1.1	0.9	-0.2
Medication: Metformin	0.3	0.5	1.6	0.1	-0.5	0.0	-0.7	-0.4	-0.9	-0.0	-0.1	0.8	0.6	-0.4	-0.1	-0.9	-1.1	-0.3	-0.8	-1.0	-1.2	0.2	-1.0	0.1	-1.3	-0.8	-0.3
Impedance of leg (right)	0.3	1.4	5.4	-1.6	-1.2	-1.5	-0.6	-0.5	-1.0	-1.1	-0.6	0.3	0.8	-1.3	-0.5	-0.4	-0.4	-0.9	-1.9	-1.5	-2.3	-0.4	-1.3	-0.9	-1.1	-1.2	-2.2
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	1.0	0.7	0.2	0.3	0.7	-0.2	0.4	-0.1	0.6	-0.8	0.0	-0.5	0.5	0.8	0.6	0.3	0.3	1.0	0.4	0.5	0.7	0.9	-0.2	0.9	1.0
Medication: Levothyroxine sodium	0.3	0.5	2.1	0.6	-0.2	0.8	-0.1	0.3	-0.3	0.2	0.5	-0.7	0.1	-0.2	-0.2	-0.4	-0.2	0.4	0.8	1.4	-0.2	1.3	0.8	1.4	-0.9	0.2	1.1
Impedance of leg (left)	0.3	1.2	4.2	-1.9	-1.0	-1.6	-0.5	-0.5	-0.7	-1.0	-0.7	0.3	0.3	-1.2	-0.7	-0.2	-0.5	-0.9	-1.7	-1.4	-1.8	-0.4	-1.0	-1.1	-0.7	-1.0	-2.1
Illnesses of siblings	0.3	0.5	1.8	-0.0	0.7	-0.1	0.9	0.8	0.6	0.6	-0.1	-0.8	0.9	1.4	-0.0	0.2	0.6	0.3	1.2	0.9	-0.4	-1.0	0.5	0.0	-1.2	-0.1	-0.2
Worrier / anxious feelings	0.3	0.6	2.7	-1.1	0.9	-1.3	0.4	-0.2	0.8	0.3	0.8	-0.1	0.0	-0.2	1.3	1.1	-0.4	0.2	0.3	0.1	0.5	-0.2	-0.6	0.6	1.6	0.9	0.8
Qualifications: A levels/AS levels or equivalent	0.3	0.6	3.5	-1.0	-1.0	-0.0	-0.7	-1.3	-1.1	-0.9	-0.3	0.6	-0.6	-1.9	-0.4	-0.5	-0.3	-0.1	-1.3	-0.3	-0.1	1.1	0.3	0.1	-0.1	-0.2	0.1
Medication: Cholesterol lowering	0.3	0.5	2.0	0.6	0.8	-0.1	0.6	0.1	0.4	0.6	1.4	-0.5	0.8	-0.2	0.9	0.7	0.5	0.8	0.3	-0.4	-0.6	1.2	0.1	1.1	0.0	0.7	0.4
Hair/balding pattern: Pattern 4	0.3	0.7	3.4	-0.0	1.3	0.7	1.0	0.8	1.1	1.3	0.8	-0.6	1.2	1.7	0.5	0.5	0.7	0.4	1.8	0.7	0.2	-0.1	0.4	0.4	0.1	0.4	-0.0
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	2.5	-0.6	-0.2	0.6	0.2	-0.1	0.3	-0.1	0.1	-0.4	0.1	-0.2	-0.2	0.5	0.1	0.4	0.6	0.3	1.5	1.6	1.3	0.1	0.9	0.6	0.4
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.3	-0.3	0.9	0.3	0.8	1.1	0.9	0.7	-0.5	-0.5	0.2	1.1	0.0	0.9	1.0	0.1	0.3	1.1	1.0	-1.0	1.1	-0.3	0.5	0.4	0.4
Number of children fathered	0.3	0.3	1.5	-0.8	0.3	-0.1	0.5	0.6	0.3	0.5	-0.3	-0.6	-1.0	1.1	-0.1	0.3	0.4	-0.1	0.2	0.6	0.2	-1.2	0.5	-0.1	-0.5	0.2	-0.1
Age at first live birth	0.3	0.5	1.5	-0.7	0.7	0.3	0.8	0.8	0.8	0.8	-0.4	-0.4	0.4	0.7	-0.1	0.7	1.1	0.3	0.9	0.8	0.7	-0.6	0.6	-0.6	1.2	0.6	-0.3
Qualifications: College or University degree	0.3	1.0	5.4	-2.3	-1.4	-0.8	-1.1	-0.9	-1.5	-0.9	-0.7	0.5	-0.3	-1.6	-0.5	-1.0	-0.5	-0.7	-0.8	-0.0	-0.9	-0.5	-0.5	-0.7	-1.3	-1.0	-0.4
Emphysema/chronic bronchitis	0.3	0.3	0.9	0.1	-0.1	-0.1	0.6	0.8	0.3	0.5	0.4	-0.9	0.3	0.4	0.4	0.3	0.6	0.6	-0.2	0.5	-0.3	-0.2	0.6	0.9	-0.9	0.4	0.8
Angina (self-reported)	0.3	0.4	2.0	-0.9	-0.5	-1.1	-0.4	-0.7	-0.3	-0.5	0.3	0.4	-1.2	-1.4	0.4	0.2	-0.6	-0.1	-0.9	-1.0	-0.8	0.4	-0.6	0.1	0.4	-0.0	-0.4
Migraine (self-reported)	0.3	0.4	1.7	-0.0	0.5	0.2	0.7	0.6	0.2	0.9	1.2	-0.3	0.7	0.7	1.3	0.6	1.1	0.4	0.5	0.5	0.0	-0.3	0.0	-0.3	0.1	-0.0	-0.6
Mean time to correctly identify matches	0.3	0.7	2.0	-0.1	0.5	0.2	0.8	0.4	0.8	0.6	0.1	-1.0	0.5	0.7	0.5	0.5	0.7	0.7	1.4	1.2	0.3	0.1	1.3	1.4	-0.4	1.0	1.2
Alcohol intake frequency.	0.3	0.7	5.1	0.2	-0.7	-0.6	-0.6	-1.0	-0.9	-0.7	-0.7	0.4	-0.5	-0.5	-0.9	-0.8	-1.0	-0.9	-0.8	0.0	-0.1	-2.3	-0.8	-0.8	-1.0	-0.6	-0.4
Had major operations	0.3	0.3	1.7	-0.1	0.5	0.2	0.3	-0.1	0.2	-0.1	0.8	-0.4	0.5	-0.1	1.0	0.5	0.6	0.1	-0.4	0.7	0.6	-1.3	-0.2	0.6	-0.1	0.5	0.9
Age at last live birth	0.3	0.4	1.6	-1.3	0.4	-0.0	0.7	0.6	0.7	0.6	-0.1	-0.3	-0.1	0.6	0.0	0.9	1.0	0.2	0.1	-0.1	0.4	-0.8	0.3	-0.9	1.1	0.4	-0.4
Illnesses of siblings: Diabetes	0.3	0.3	2.7	-0.2	0.4	-0.2	0.1	0.2	0.6	0.2	-0.0	0.4	-0.3	-0.0	0.3	0.8	0.2	0.1	-0.6	-0.7	0.8	1.0	0.2	-0.6	1.6	0.5	-0.1
Diabetes diagnosed by doctor	0.3	0.5	3.1	1.8	0.9	0.4	0.2	0.5	0.5	1.0	0.1	0.2	0.8	1.3	0.3	-0.1	-0.2	0.7	0.9	-0.5	-0.3	0.7	-0.2	0.8	-0.2	0.2	0.3
Osteoarthritis (self-reported)	0.3	0.5	2.0	1.0	0.7	1.2	0.5	0.5	0.5	0.7	-0.2	-0.8	0.2	0.9	0.3	0.1	0.5	0.5	0.6	0.5	-0.1	1.4	0.3	1.2	-0.1	0.3	0.5
Tinnitus: Yes, now most or all of the time	0.3	0.3	2.0	-0.0	0.2	0.9	0.4	-0.1	-0.0	-0.1	0.0	-0.8	0.1	-0.1	0.6	0.1	0.1	0.0	0.6	1.0	-0.2	-0.6	-0.9	0.6	-1.4	-0.1	0.2
Medication: Bendroflumethiazide	0.3	0.4	2.0	0.2	-0.6	1.1	-0.9	-0.4	-0.2	-0.2	1.0	1.3	-0.7	-0.5	0.4	-0.2	-0.7	-0.2	-0.4	-0.9	0.2	0.4	-1.4	-0.7	0.5	-0.0	-0.1
Medication: Paracetamol	0.3	0.4	2.1	0.5	0.7	0.1	0.3	0.9	0.3	0.9	1.2	-0.1	-0.7	0.8	1.5	0.3	0.0	0.8	-0.5	-0.3	0.1	1.1	-0.2	0.8	0.6	0.1	0.4
Age started oral contraceptive pill	0.3	0.3	1.6	0.2	0.4	0.2	0.6	0.6	0.5	0.4	0.8	-0.5	0.8	-0.2	0.7	1.0	0.6	0.5	0.3	0.6	-0.1	1.2	0.0	0.5	0.8	0.5	0.1
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.1	0.6	1.1	-0.1	0.8	0.7	0.7	0.8	0.1	-1.0	0.5	0.9	0.1	0.7	0.7	0.5	0.6	0.0	0.2	0.5	0.9	0.6	-0.4	0.3	-0.0
Impedance of whole body	0.3	1.4	4.6	-1.6	-1.1	-2.1	-0.6	-0.8	-0.9	-1.3	-0.9	0.4	0.1	-1.6	-0.7	-0.2	-0.5	-0.9	-1.9	-1.6	-1.8	0.1	-1.2	-1.1	-0.4	-1.1	-2.1
Schizophrenia vs Biploar Disorder	0.2	0.3	2.5	0.3	-0.4	-0.4	-0.0	0.3	-0.1	-0.3	0.6	-0.2	0.1	-0.5	-0.1	0.6	0.1	0.2	-1.6	-1.1	-0.8	0.7	-0.7	0.5	-0.1	-0.0	-0.3
Crohns Disease (2017)	0.2	0.4	1.6	0.2	0.1	-0.5	-0.5	-0.9	-0.2	-0.2	0.6	0.5	-0.8	-1.3	0.2	0.5	-0.8	-0.2	-0.9	0.2	1.1	0.9	0.4	0.2	0.8	0.3	0.8
Irritable Bowel Disease (IBD)	0.2	0.5	3.0	-0.7	-0.4	-1.1	-0.6	-1.0	-0.5	-0.6	-0.3	0.3	-1.7	-1.3	-0.7	-0.2	-0.9	-0.6	-0.4	0.5	0.2	0.0	0.5	0.0	-0.0	-0.1	0.4
Ulcerative Colitis (UC)	0.2	0.4	2.4	-0.8	-0.3	-1.1	-0.3	-0.4	-0.3	-0.5	-0.9	-0.1	-1.6	-0.5	-1.0	-0.5	-0.4	-0.5	0.4	0.7	-0.3	-0.5	0.7	0.0	-0.1	-0.1	0.3
Reaction Time	0.2	0.3	1.1	-0.6	0.3	0.2	0.4	0.4	0.5	0.4	-0.0	-0.5	0.4	0.9	0.4	0.1	0.0	0.5	0.8	0.9	0.3	-0.4	0.9	1.1	-0.6	0.6	1.0
Ovarian Cancer	0.2	0.2	1.2	-0.3	-0.7	-0.1	-0.6	-0.5	-0.4	-0.4	-0.2	0.1	-1.1	-0.8	-0.2	-0.5	-0.7	-0.3	-0.7	-0.4	-0.8	-0.1	-0.0	-0.1	-0.2	-0.2	-0.2
Cardiovascular Disease	0.2	0.7	3.2	1.3	-0.7	0.7	-1.1	-0.8	-0.3	-0.5	0.6	0.8	-1.8	-0.6	0.3	-0.5	-1.3	0.3	-0.6	-0.7	-0.1	1.2	-1.1	0.7	0.7	0.5	0.5
Hypothyroidism (self reported)	0.2	0.5	2.5	0.3	0.1	0.9	0.3	0.1	-0.1	0.2	0.2	-0.9	0.1	-0.4	-0.1	0.1	0.2	0.6	0.5	1.6	0.2	1.3	1.1	1.4	-0.4	0.6	1.3
Sensitivity / hurt feelings	0.2	0.3	1.4	0.6	0.9	-0.5	0.4	0.6	0.7	0.6	0.4	-0.2	1.2	0.6	0.5	0.7	-0.1	0.3	0.3	0.6	0.4	0.4	0.3	0.8	-0.0	0.5	0.9
Frequency of depressed mood in last 2 weeks	0.2	0.2	1.2	0.5	-0.4	-0.3	-0.5	-0.8	-0.2	-0.4	-0.6	0.3	-0.1	-0.3	-0.2	-0.5	-1.0	-0.2	0.2	-0.7	0.1	1.1	-0.1	0.3	-0.7	-0.2	-0.1
Relative age of first facial hair	0.2	0.5	2.0	-0.1	0.5	0.5	0.4	0.1	0.3	0.5	0.8	-0.5	-0.6	0.2	0.8	0.7	0.1	0.6	0.8	0.5	0.8	1.4	0.4	1.4	0.3	0.7	1.0
Supplements: Zinc	0.2	0.2	0.8	-0.1	0.7	0.4	0.6	0.5	0.5	0.5	0.0	-0.2	0.6	0.1	0.5	0.6	0.4	0.4	-0.3	0.4	0.9	-0.0	0.2	-0.0	0.7	0.6	0.4
Fed-up feelings	0.2	0.4	1.1	0.8	0.5	0.2	0.4	-0.1	0.4	0.3	0.7	-0.4	1.1	0.2	0.4	0.5	0.2	0.5	0.4	0.5	0.8	1.0	0.6	1.0	0.1	0.7	1.0
Qualifications: CSEs or equivalent	0.2	0.2	1.1	-0.4	0.3	-0.2	-0.2	-0.2	-0.0	-0.2	-1.0	0.4	-0.9	0.5	-0.5	-0.2	-0.4	-0.3	0.2	-0.2	0.2	-0.7	-0.9	-0.2	0.0	-0.2	0.1
High blood pressure (mother)	0.2	0.3	2.1	0.3	0.3	0.9	0.1	0.2	0.1	0.7	0.3	-0.6	-0.2	0.1	0.9	-0.1	0.1	0.7	0.4	0.5	0.1	0.5	0.4	1.4	-1.0	0.4	0.9
Forced vital capacity (FVC)	0.2	0.9	4.3	1.2	2.1	1.0	1.3	0.5	1.1	1.1	-0.0	-0.9	1.5	1.0	0.5	0.8	1.2	0.7	0.8	1.1	0.7	0.1	0.6	0.6	0.5	0.8	0.4
Mouth/teeth dental problems	0.2	0.3	1.4	-0.1	0.3	0.2	0.2	0.6	0.3	0.6	0.2	-0.3	-0.3	0.6	0.3	0.3	0.6	0.6	0.6	0.3	1.2	0.6	0.8	0.3	0.2	0.5	0.5
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	0.6	-0.8	0.4	0.0	0.6	0.5	0.5	0.2	0.5	-0.1	-0.2	0.1	0.3	0.7	0.8	0.0	-0.3	-0.4	-0.6	-0.6	-0.5	-0.6	0.0	0.0	-0.6
Medication: Simvastatin	0.2	0.4	1.9	0.4	-0.2	-0.7	-0.1	-0.6	0.3	-0.5	0.9	0.4	0.1	-1.2	0.2	0.7	0.3	0.1	-0.7	-1.0	-0.1	0.0	-0.1	-0.6	1.4	0.5	-0.4
Impedance of arm (right)	0.2	0.9	2.6	-1.2	-0.4	-1.6	-0.0	-0.5	-0.5	-0.7	-0.5	0.1	0.9	-1.4	0.0	0.7	0.1	-0.3	-1.5	-1.6	-1.5	0.8	-1.4	-0.4	-0.2	-0.6	-1.6
Falls in the last year	0.2	0.3	1.9	1.2	-0.2	0.5	-0.4	-0.4	-0.1	0.1	0.1	0.2	-0.3	-0.5	0.4	-0.1	0.0	0.2	-0.8	-0.2	0.2	1.4	0.3	0.2	0.9	0.3	0.1
Hair/balding pattern: Pattern 3	0.2	0.3	1.8	-0.6	-0.3	0.1	-0.4	-0.2	-0.4	-0.2	-0.5	0.1	-1.0	0.3	-0.9	-0.8	-0.2	-0.4	1.3	0.6	0.4	-0.0	0.4	-0.4	-0.2	-0.5	-0.3
Depression (self-reported)	0.2	0.2	2.1	1.5	0.1	-0.2	-0.2	0.2	0.1	0.3	-0.2	0.1	0.7	0.1	-0.7	0.1	-0.4	0.1	-0.2	-0.2	0.4	0.6	0.7	0.5	0.1	0.1	0.2
Length of working week for main job	0.2	0.2	1.2	-0.1	0.3	0.0	0.1	0.4	0.2	0.6	0.6	-0.5	-0.3	0.5	0.2	0.2	-0.4	0.3	-1.1	-0.3	0.4	0.2	0.7	0.7	0.7	0.5	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.8	0.1	0.2	0.3	-0.1	0.0	0.1	0.3	1.1	-0.5	-0.0	0.1	0.8	0.0	-0.7	0.4	0.4	0.6	-0.1	0.1	0.1	1.2	-1.4	-0.1	0.7
Gout (self-reported)	0.2	0.3	2.0	0.4	-0.1	0.9	-0.2	-0.4	-0.5	0.0	-0.2	-0.2	0.6	0.3	-0.2	-0.6	-0.0	0.2	0.5	0.3	-0.1	1.0	0.6	0.9	-1.4	-0.1	0.7
High blood pressure (siblings)	0.2	0.3	1.0	0.5	-0.9	0.4	-1.0	-0.8	-0.8	-0.4	-0.0	0.5	-0.4	-0.9	-0.1	-0.7	-0.9	-0.4	-0.6	-0.5	-0.0	0.8	-0.3	0.4	-0.0	-0.2	0.3
Forced vital capacity (FVC), Best measure	0.2	0.8	3.8	0.9	1.9	0.8	1.2	0.5	0.9	1.1	-0.1	-0.9	1.4	0.9	0.3	0.7	1.1	0.5	1.0	1.3	0.6	-0.2	0.2	0.7	-0.0	0.6	0.5
Shortness of breath walking on level ground	0.2	0.2	0.8	-0.6	-0.1	-0.8	-0.3	-0.3	-0.4	-0.2	-0.9	0.6	0.4	-0.3	-0.4	-0.4	-0.3	-0.3	-0.7	-0.5	-0.2	-0.5	-0.2	-0.3	0.0	-0.4	-0.2
Commuting to job workplace: Car/motor vehicle	0.2	0.3	2.6	-0.0	-0.0	-0.0	-0.1	0.1	0.2	0.2	-0.1	0.1	0.2	0.3	0.4	-0.1	-0.1	0.4	1.6	0.4	0.1	1.1	0.8	0.3	1.0	0.4	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.5	1.1	1.2	0.7	0.8	0.1	0.4	0.9	-0.0	-0.4	0.6	0.4	0.9	0.7	0.7	0.5	-0.6	0.7	0.9	-0.3	0.2	0.3	0.7	0.7	0.8
Qualifications: nursing, teaching	0.2	0.3	1.4	-0.9	-1.0	-0.1	-0.2	-0.6	-0.5	-0.8	-0.7	-0.2	-1.2	-0.7	-0.7	-0.2	0.3	-0.2	-1.1	-0.2	0.2	0.4	0.5	-0.2	-0.3	-0.0	-0.2
Commuting to job workplace: Walk	0.2	0.2	0.9	-0.1	-0.1	-0.5	-0.3	0.1	-0.2	-0.2	0.3	0.6	0.4	0.2	-0.0	-0.3	-1.0	-0.5	-1.0	-0.5	-0.4	-0.7	-0.7	-0.7	-0.1	-0.4	-0.7
Number of self-reported non-cancer illnesses	0.2	0.3	1.9	0.2	-0.5	-0.7	-0.4	-0.3	-0.7	-0.0	0.4	0.1	0.4	-0.4	0.3	-0.3	-0.6	-0.2	-0.6	-0.4	-1.4	0.8	-0.4	0.9	-0.7	-0.3	0.1
Mother’s age at death	0.2	0.3	1.9	0.4	-0.2	0.3	0.3	-0.0	0.3	-0.2	-0.3	-0.6	0.4	-0.1	0.2	0.3	0.5	0.3	0.3	0.7	0.9	0.8	0.9	-0.0	1.4	0.6	0.4
Financial situation satisfaction	0.2	0.2	1.7	0.6	-0.2	1.1	-0.3	0.0	-0.4	0.2	0.3	0.2	0.1	-0.3	0.2	-0.4	0.2	0.3	0.1	0.2	0.6	1.3	0.2	0.2	0.2	-0.1	0.3
Pain type(s) experienced in last month: Hip pain	0.2	0.3	1.4	0.8	0.2	0.1	-0.0	-1.0	-0.0	-0.3	-0.4	0.0	-0.8	-0.3	-0.3	-0.3	-0.3	-0.1	0.2	-0.1	0.4	0.7	0.4	0.9	-0.4	0.1	1.2
Unable to work because of sickness or disability	0.2	0.2	0.6	-0.0	-0.2	0.5	0.3	0.3	0.3	-0.2	0.2	-0.3	-0.1	-0.6	0.6	0.6	0.5	0.7	-0.6	-0.2	-0.2	0.8	-0.1	0.7	0.0	0.6	0.4
Cholesterol lowering medication	0.2	0.3	1.2	0.5	-0.1	0.1	-0.1	-0.4	0.2	-0.4	1.1	0.2	-0.3	-1.1	0.6	0.8	0.1	0.0	-0.8	-0.1	0.0	0.6	-0.3	0.4	0.8	0.6	0.5
Heart disease (siblings)	0.2	0.2	1.2	0.3	-0.2	0.1	0.2	-0.0	0.0	-0.4	0.4	0.2	-0.6	-1.1	-0.0	0.4	0.4	0.2	-0.8	-0.7	0.5	1.0	0.3	-0.2	0.8	0.1	-0.2
Depressed Affect (Nagel 2018)	0.1	0.3	1.6	0.5	-0.0	-0.4	-0.8	-1.3	-0.5	-0.4	-0.3	0.7	-0.1	-0.3	-0.4	-0.7	-0.9	-0.5	-0.1	-0.3	0.1	-0.2	-0.6	0.3	-0.4	-0.3	0.1
Breast Cancer	0.1	0.2	1.0	-0.9	-0.4	1.0	-0.2	0.1	-0.5	-0.0	0.1	-0.2	-0.3	0.4	-0.2	-0.6	-0.2	0.0	0.9	0.6	0.1	-0.0	-0.3	0.3	-0.9	-0.5	-0.1
Mean Putamen Volume	0.1	0.1	0.7	-0.1	-0.4	0.0	-0.1	0.2	0.1	-0.2	-0.3	0.2	-0.2	0.8	-0.2	-0.4	-0.1	0.1	0.3	-0.2	-0.2	-0.2	-0.1	-0.3	0.3	0.0	-0.5
Lupus	0.1	0.2	1.3	0.1	0.1	0.1	-0.0	-0.4	-0.2	-0.0	-0.1	-0.0	-0.5	-1.2	0.4	-0.1	0.4	0.2	-0.5	-0.2	0.5	0.8	-0.2	0.4	0.3	0.0	0.2
Blood Platelet Count	0.1	0.9	4.5	-1.4	1.4	-0.3	0.7	-0.1	1.0	0.7	0.7	0.6	0.4	-0.1	1.4	1.9	0.2	0.1	-0.5	-1.7	0.6	0.6	-0.3	-0.8	2.1	0.6	-0.3
Blood White Count	0.1	0.7	5.2	1.0	0.5	-1.0	0.1	-0.4	0.4	0.2	0.8	0.9	1.4	-0.6	0.9	1.3	-0.5	0.1	-0.5	-1.0	0.6	1.0	-0.3	-0.5	2.3	0.6	0.2
Waist Hip Ratio (WHR)	0.1	0.5	6.9	0.7	-0.7	-0.1	-0.1	-0.4	-0.4	-0.7	0.0	-0.1	-0.4	-0.7	0.1	-0.5	-0.4	0.0	-2.6	-0.6	-0.5	0.3	-0.6	0.5	-0.3	0.0	0.1
Tanning	0.1	1.1	3.0	1.4	-0.7	-0.6	-1.0	-1.7	-1.1	-1.5	-1.6	0.8	-0.1	-1.4	-1.4	-1.4	-1.0	-1.2	-1.0	-0.1	-0.6	-0.7	-0.8	-0.9	-0.0	-1.1	-0.8
Systolic blood pressure, automated reading	0.1	0.4	2.4	-0.5	-0.6	-0.5	-0.7	-1.3	-0.5	-1.0	0.3	0.6	-0.1	-1.6	-0.1	-0.2	-0.6	-0.7	-0.0	-0.2	-0.6	-0.8	-0.6	-0.4	-0.4	-0.0	-0.2
Diabetes (mother)	0.1	0.1	0.7	0.4	-0.3	-0.2	-0.3	-0.4	-0.4	-0.1	0.1	0.1	0.7	-0.5	0.2	-0.5	-0.7	0.0	-0.3	0.3	0.3	-0.3	0.0	0.5	-0.2	0.1	0.8
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.6	-0.3	-0.1	-0.1	0.5	0.5	0.4	0.2	-0.0	-0.8	0.4	0.1	0.1	0.2	0.5	0.4	-0.5	-0.2	0.0	0.3	0.7	0.3	0.3	0.3	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	1.0	-0.1	-0.4	-0.6	-0.4	-0.2	0.0	-0.4	-0.5	-0.1	-1.0	-0.0	-0.2	-0.0	-0.5	0.1	-0.7	-0.2	0.6	-0.3	0.3	0.1	-0.3	0.2	0.5
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	1.7	0.7	1.3	0.8	0.3	-0.4	0.2	0.4	-0.3	-0.0	1.1	0.2	0.3	0.0	0.3	0.1	-0.1	0.6	0.4	-0.3	-0.3	0.1	0.4	0.1	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	2.1	0.6	1.4	0.7	0.3	-0.1	0.2	0.6	-0.4	0.0	1.1	0.5	0.1	-0.1	0.2	0.0	0.5	1.1	0.5	-0.7	-0.4	0.3	-0.0	0.1	0.4
Impedance of arm (left)	0.1	0.6	2.9	-0.7	-0.4	-1.7	-0.0	-0.5	-0.3	-0.8	-0.9	-0.1	0.5	-1.2	-0.4	0.4	0.2	-0.2	-1.2	-1.1	-1.0	1.0	-0.7	-0.5	0.1	-0.4	-1.4
Breastfed as a baby	0.1	0.2	0.6	0.7	-0.1	0.4	-0.4	-0.2	-0.2	-0.3	-0.5	0.6	0.5	0.2	-0.4	-0.6	0.1	-0.2	-0.7	-0.5	-0.5	0.2	-0.0	-0.3	-0.1	-0.2	-0.4
Peak expiratory flow (PEF)	0.1	0.3	2.5	1.6	0.6	0.8	-0.0	-0.3	0.0	0.1	-0.3	0.3	0.9	0.6	0.2	-0.3	0.0	0.2	-0.8	0.6	0.6	0.1	0.2	0.2	0.6	0.2	0.8
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	1.6	-0.2	-0.2	0.5	0.0	0.1	-0.3	0.0	0.5	-0.5	-0.2	-0.5	-0.1	0.1	-0.0	0.3	0.3	1.0	-0.0	1.3	0.7	0.7	-0.4	0.1	0.5
Medication for cholesterol	0.1	0.2	0.9	-0.6	-0.2	-0.4	-0.1	0.0	-0.7	0.1	-0.8	0.0	1.0	0.1	-0.6	-0.6	-0.3	-0.1	-0.4	-0.1	-0.4	-0.4	-0.3	0.2	-0.6	-0.8	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.4	-0.6	0.0	-0.2	-0.2	-0.3	-0.5	0.3	-0.5	0.0	-0.5	-0.1	-0.2	-0.6	-0.3	-0.2	0.4	-0.1	-0.4	-0.3	-0.4	0.1	-0.6	-0.4	-0.1
Back pain experienced in last month	0.1	0.1	0.4	0.6	0.1	0.2	0.2	-0.1	-0.1	0.4	0.3	-0.2	-0.5	0.4	0.3	0.1	-0.0	-0.1	0.1	0.1	-0.4	0.4	-0.2	0.4	-0.5	-0.0	0.2
Miserableness	0.1	0.2	0.9	0.6	-0.1	-0.2	-0.8	-0.9	-0.3	-0.2	0.2	0.5	-0.6	-0.3	0.1	-0.6	-1.0	-0.1	-0.2	-0.0	0.7	0.4	0.1	0.6	0.2	0.3	0.7
Pain experienced in last month	0.1	0.2	1.0	-0.6	0.0	0.2	0.1	-0.4	0.1	-0.6	-0.7	0.0	0.0	-0.6	-0.8	0.0	0.4	-0.4	0.3	0.1	-0.2	-1.0	-0.5	-0.7	0.3	-0.1	-0.4
Hair Pigment	0.0	0.6	2.7	-0.2	-0.4	0.0	-0.3	-0.4	0.1	-0.5	0.9	0.6	-1.2	-0.1	0.0	0.3	-0.0	-0.4	-1.2	-1.6	0.2	0.6	-0.4	-1.2	1.6	-0.0	-1.2

Hub : Genes

ACYP2

Models

Trait associations