Hub : Genes

ACYP2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0570 0.0220 2.3e-04 0.024 0.034 0.017 0.033 0.024 5.0e-04 4.8e-05 3.1e-03 5.6e-05 5.3e-04
2 GTEx Cells Transformed fibroblasts 0.2000 0.0510 7.7e-10 0.094 NA 0.192 NA 0.180 1.7e-07 NA 2.5e-14 NA 1.7e-13
3 GTEx Colon Sigmoid 0.3470 0.0860 9.6e-08 0.090 NA 0.184 NA 0.181 4.3e-04 NA 4.6e-07 NA 5.7e-07
4 GTEx Colon Transverse 0.2650 0.0650 2.4e-09 0.318 NA 0.267 NA 0.056 1.0e-15 NA 4.8e-13 NA 1.1e-03
5 GTEx Esophagus Gastroesophageal Junction 0.1620 0.0530 1.2e-04 0.174 NA 0.076 NA 0.064 7.3e-07 NA 1.0e-03 NA 2.5e-03
6 GTEx Esophagus Mucosa 0.2540 0.0590 1.9e-12 0.215 NA 0.220 NA 0.245 2.1e-14 NA 9.2e-15 NA 1.9e-16
7 GTEx Esophagus Muscularis 0.2370 0.0500 9.9e-14 0.251 NA 0.250 NA 0.243 2.2e-15 NA 2.5e-15 NA 6.3e-15
8 GTEx Lung 0.1325 0.0388 5.0e-07 0.119 NA 0.083 NA 0.101 2.3e-09 NA 6.1e-07 NA 3.7e-08
9 GTEx Muscle Skeletal 0.2339 0.0450 0.0e+00 0.254 NA 0.210 NA 0.252 7.5e-25 NA 2.4e-20 NA 1.4e-24
10 GTEx Nerve Tibial 0.1237 0.0410 6.6e-05 0.042 NA 0.068 NA 0.061 6.1e-04 NA 1.4e-05 NA 3.9e-05
11 GTEx Ovary 0.2690 0.0930 1.3e-03 0.162 NA 0.014 NA 0.077 8.7e-05 NA 1.4e-01 NA 6.2e-03
12 GTEx Skin Not Sun Exposed Suprapubic 0.0930 0.0390 1.4e-03 0.100 NA 0.066 NA 0.088 4.1e-06 NA 1.7e-04 NA 1.5e-05
13 GTEx Stomach 0.1610 0.0640 5.3e-04 0.044 NA 0.053 NA 0.057 3.7e-03 NA 1.5e-03 NA 1.1e-03
14 GTEx Testis 0.1230 0.0490 9.0e-04 0.069 NA 0.054 NA 0.074 5.6e-04 NA 2.0e-03 NA 3.3e-04
15 GTEx Thyroid 0.1300 0.0390 5.1e-07 0.057 NA 0.067 NA 0.076 3.4e-05 NA 7.9e-06 NA 1.8e-06
16 NTR Blood 0.0247 0.0089 8.4e-06 0.020 0.012 0.018 0.013 0.017 3.8e-07 7.9e-05 8.9e-07 4.5e-05 2.5e-06
17 ROSMAP Brain Pre-frontal Cortex 0.0932 0.0332 8.2e-06 0.023 0.021 0.023 0.026 0.031 5.3e-04 8.2e-04 5.2e-04 2.1e-04 6.3e-05
18 TCGA Bladder Urothelial Carcinoma 0.0680 0.0380 5.2e-03 0.004 0.021 0.013 NA 0.026 1.4e-01 6.1e-03 2.5e-02 NA 2.7e-03
19 TCGA Breast Invasive Carcinoma 0.0170 0.0090 4.4e-03 0.004 0.006 0.004 NA 0.003 3.5e-02 2.0e-02 4.1e-02 NA 7.6e-02
20 TCGA Kidney Renal Clear Cell Carcinoma 0.0386 0.0218 8.2e-03 0.019 0.007 0.015 NA 0.009 2.5e-03 4.9e-02 6.6e-03 NA 2.7e-02
21 TCGA Brain Lower Grade Glioma 0.0637 0.0323 5.4e-04 0.037 0.018 0.025 NA 0.032 4.0e-05 3.5e-03 6.5e-04 NA 1.3e-04
22 TCGA Lung Squamous Cell Carcinoma 0.0742 0.0298 3.3e-04 0.019 0.021 0.044 NA 0.041 2.5e-03 1.8e-03 8.9e-06 NA 1.6e-05
23 TCGA Prostate Adenocarcinoma 0.2072 0.0657 6.0e-12 0.154 0.125 0.154 NA 0.158 7.2e-16 5.9e-13 7.2e-16 NA 3.0e-16
24 TCGA Thyroid Carcinoma 0.1550 0.0460 1.5e-08 0.085 0.094 0.117 NA 0.115 1.2e-08 2.2e-09 2.0e-11 NA 2.8e-11

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bipolar Disorder (2018) 0.8 1.3 3.5 -0.4 1.6 1.1 1.4 0.4 1.1 1.2 1.4 -1.2 1.1 0.6 1.9 1.8 1.0 1.1 0.6 1.0 0.7 0.8 0.7 1.3 0.5 1.4 1.0
Bipolar Disorder or Schizophrenia 0.7 1.7 5.4 -0.5 1.0 0.8 1.6 1.2 0.9 1.1 2.3 -1.5 1.6 0.2 2.2 2.1 1.2 1.5 -0.3 -0.2 -0.3 1.8 0.3 2.0 0.0 1.1 0.4
Depressed Affect (Nagel 2018) 0.1 0.3 1.6 0.5 -0.0 -0.4 -0.8 -1.3 -0.5 -0.4 -0.3 0.7 -0.1 -0.3 -0.4 -0.7 -0.9 -0.5 -0.1 -0.3 0.1 -0.2 -0.6 0.3 -0.4 -0.3 0.1
Depression (Nagel 2018) 0.6 1.0 3.7 0.8 -0.8 -0.7 -1.1 -1.9 -1.0 -1.3 -1.1 1.1 -0.3 -1.5 -0.9 -1.0 -1.4 -0.8 -0.3 -1.2 -0.3 0.9 -0.7 -0.2 -0.8 -0.7 -0.8
Intelligence (Savage-Jansen 2018) 2.9 8.8 15.0 2.8 2.7 3.1 3.3 3.3 2.9 3.2 3.1 -3.7 1.5 1.9 2.9 3.0 3.2 3.7 1.6 2.6 3.0 3.7 2.7 3.9 0.3 3.0 3.5
Neuroticism (Nagel 2018) 0.5 1.1 3.6 0.8 1.5 -0.1 0.6 0.2 1.0 1.1 1.6 -0.9 0.6 0.4 1.3 0.9 0.1 0.9 0.8 0.9 0.8 1.1 1.0 1.9 0.7 1.1 1.7
Schizophrenia (2018) 0.4 0.9 3.6 -0.4 -0.0 0.2 0.9 1.2 0.3 0.5 1.9 -0.9 1.2 -0.2 1.3 1.3 0.7 0.9 -0.8 -1.0 -1.0 1.7 -0.3 1.6 -0.4 0.3 -0.3
Schizophrenia vs Biploar Disorder 0.2 0.3 2.5 0.3 -0.4 -0.4 -0.0 0.3 -0.1 -0.3 0.6 -0.2 0.1 -0.5 -0.1 0.6 0.1 0.2 -1.6 -1.1 -0.8 0.7 -0.7 0.5 -0.1 -0.0 -0.3
Worry (Nagel 2018) 1.2 2.5 7.2 0.5 2.2 0.0 1.6 1.3 2.0 1.9 1.5 -1.9 0.3 0.9 1.2 1.7 0.8 1.7 1.5 1.3 1.3 1.8 1.6 2.7 0.9 1.9 2.1
Alzheimer’s Disease (in mother) 0.4 0.4 3.3 -0.5 0.4 -0.2 0.3 0.0 0.7 0.2 1.3 0.0 -0.1 0.1 0.8 1.1 -0.0 0.3 0.0 -0.3 0.3 1.4 0.1 -0.1 1.8 0.5 -0.2
Alzheimer’s Disease (in father) 0.5 0.5 2.6 -0.7 -0.8 -1.3 -0.3 -0.5 -0.1 -0.7 0.1 0.4 -0.7 -1.2 0.2 0.3 0.0 -0.4 -1.2 -0.5 0.2 -0.9 0.0 -0.9 1.6 0.3 -0.3
Alzheimer’s Disease (including proxy) 0.4 0.6 6.5 -0.7 0.2 -0.9 0.2 0.1 0.8 -0.1 1.1 0.2 -0.1 -0.5 0.8 1.3 0.3 0.2 -0.7 -0.4 0.3 0.6 0.4 -0.8 2.5 0.7 0.0
Crohns Disease (2017) 0.2 0.4 1.6 0.2 0.1 -0.5 -0.5 -0.9 -0.2 -0.2 0.6 0.5 -0.8 -1.3 0.2 0.5 -0.8 -0.2 -0.9 0.2 1.1 0.9 0.4 0.2 0.8 0.3 0.8
Irritable Bowel Disease (IBD) 0.2 0.5 3.0 -0.7 -0.4 -1.1 -0.6 -1.0 -0.5 -0.6 -0.3 0.3 -1.7 -1.3 -0.7 -0.2 -0.9 -0.6 -0.4 0.5 0.2 0.0 0.5 0.0 -0.0 -0.1 0.4
Ulcerative Colitis (UC) 0.2 0.4 2.4 -0.8 -0.3 -1.1 -0.3 -0.4 -0.3 -0.5 -0.9 -0.1 -1.6 -0.5 -1.0 -0.5 -0.4 -0.5 0.4 0.7 -0.3 -0.5 0.7 0.0 -0.1 -0.1 0.3
Major Depression (MDD) 0.3 0.3 1.9 0.2 -0.2 0.3 -0.6 -0.2 -0.2 -0.3 -0.4 0.7 -0.4 0.4 -0.8 -0.3 -0.2 -0.1 -1.4 -0.8 -0.2 0.1 0.3 -0.7 1.3 -0.2 -0.2
Reaction Time 0.2 0.3 1.1 -0.6 0.3 0.2 0.4 0.4 0.5 0.4 -0.0 -0.5 0.4 0.9 0.4 0.1 0.0 0.5 0.8 0.9 0.3 -0.4 0.9 1.1 -0.6 0.6 1.0
Verbal and Numeric Reasoning (VNR) 5.2 12.4 18.5 3.4 3.4 3.6 3.7 3.8 3.5 3.8 3.6 -4.0 2.8 2.5 3.5 3.6 3.8 4.3 2.6 3.2 3.3 4.3 3.2 4.2 1.3 3.9 3.9
Breast Cancer 0.1 0.2 1.0 -0.9 -0.4 1.0 -0.2 0.1 -0.5 -0.0 0.1 -0.2 -0.3 0.4 -0.2 -0.6 -0.2 0.0 0.9 0.6 0.1 -0.0 -0.3 0.3 -0.9 -0.5 -0.1
Ovarian Cancer 0.2 0.2 1.2 -0.3 -0.7 -0.1 -0.6 -0.5 -0.4 -0.4 -0.2 0.1 -1.1 -0.8 -0.2 -0.5 -0.7 -0.3 -0.7 -0.4 -0.8 -0.1 -0.0 -0.1 -0.2 -0.2 -0.2
Prostate Cancer 0.8 1.1 5.8 1.3 0.9 0.8 0.7 -0.0 0.6 0.9 0.5 -0.9 -0.2 0.4 0.3 0.5 0.5 1.0 1.3 1.0 1.4 2.4 1.7 1.5 0.2 1.1 1.7
Age at First Birth 0.3 0.5 3.6 -0.3 0.7 -0.7 0.8 0.5 0.6 0.5 0.7 -0.3 0.3 0.2 0.7 1.5 1.0 0.3 -0.6 -0.0 0.2 0.3 -0.0 -0.5 1.9 0.7 -0.3
Bipolar Disorder (2011) 1.0 0.9 2.7 -0.5 0.8 0.5 0.8 0.6 0.9 0.7 1.3 -1.3 0.3 0.7 1.4 1.0 0.7 0.9 0.5 1.6 0.8 0.2 1.0 1.4 0.5 1.3 1.4
Body Mass Index (BMI) (2010) 5.2 7.2 11.8 2.9 2.9 2.7 2.8 3.0 2.8 3.0 2.2 -2.6 2.4 2.6 2.2 2.5 2.9 2.9 2.3 2.9 3.4 1.8 2.8 2.6 1.5 2.9 3.0
Coronary Artery Disease (CAD) 0.3 0.3 1.1 1.0 0.7 0.1 0.8 0.0 0.5 0.4 -0.2 -0.9 1.0 0.4 -0.2 0.5 0.3 0.1 0.7 0.6 0.5 0.6 0.5 0.5 -0.5 0.0 -0.1
Crohns Disease (2012) 0.5 0.7 3.4 -0.7 -0.8 -1.0 -1.0 -1.4 -0.7 -0.8 -0.5 0.7 -1.4 -1.8 -0.5 -0.4 -1.1 -0.8 -1.4 -0.5 0.3 0.0 -0.3 -0.1 -0.0 -0.2 0.5
Mean Putamen Volume 0.1 0.1 0.7 -0.1 -0.4 0.0 -0.1 0.2 0.1 -0.2 -0.3 0.2 -0.2 0.8 -0.2 -0.4 -0.1 0.1 0.3 -0.2 -0.2 -0.2 -0.1 -0.3 0.3 0.0 -0.5
Fasting Glucose 1.9 2.3 6.5 -0.3 -1.6 -1.8 -2.0 -0.6 -1.3 -1.6 -2.2 1.7 -1.1 -0.4 -2.5 -2.0 -2.0 -1.7 -0.9 -1.4 -1.0 -1.4 -1.0 -1.7 -1.1 -1.5 -1.3
HbA1C 1.1 1.3 4.5 2.1 1.1 1.1 1.0 -0.0 0.7 1.5 0.9 -0.7 2.0 1.0 1.2 0.7 1.3 1.4 0.8 0.8 0.2 1.0 1.3 1.3 -0.9 0.4 1.1
HDL Cholesterol 5.4 8.9 11.2 -3.3 -3.0 -3.3 -3.1 -3.2 -3.3 -3.1 -3.3 2.9 -3.0 -3.2 -3.1 -3.1 -3.3 -3.2 -2.1 -3.1 -3.1 -1.3 -2.7 -2.5 -2.0 -3.3 -3.0
LDL Cholesterol 1.2 1.9 4.8 -1.0 -1.2 -1.2 -1.3 -1.4 -1.8 -1.1 -0.8 1.3 0.1 -1.5 -1.4 -1.4 -1.6 -1.3 -0.5 -1.3 -2.0 -1.0 -1.8 -0.7 -2.2 -1.8 -1.0
Lupus 0.1 0.2 1.3 0.1 0.1 0.1 -0.0 -0.4 -0.2 -0.0 -0.1 -0.0 -0.5 -1.2 0.4 -0.1 0.4 0.2 -0.5 -0.2 0.5 0.8 -0.2 0.4 0.3 0.0 0.2
Neuroticism (2016) 1.2 1.8 6.3 0.8 1.5 0.7 0.8 1.2 1.5 1.4 2.5 -0.4 1.5 0.7 2.1 1.7 0.4 1.1 0.1 0.4 1.4 1.7 0.6 0.9 2.3 1.4 1.2
Primary Biliary Cirrhosis 1.5 2.2 6.5 -1.7 -2.3 -0.9 -1.8 -1.3 -1.9 -2.0 -1.4 1.2 -2.5 -1.4 -1.6 -1.8 -1.4 -1.4 -0.9 -0.7 -1.1 -0.6 -1.0 -1.1 -1.1 -1.5 -1.3
Rheumatoid Arthritis 2.7 3.8 6.9 -1.2 -1.5 -2.2 -2.1 -2.1 -1.9 -1.9 -1.4 2.5 -1.2 -1.8 -1.3 -1.5 -2.0 -2.4 -1.8 -2.0 -2.0 -2.2 -2.6 -2.5 -0.2 -2.1 -2.5
Schizophrenia (2014) 1.0 2.2 8.2 -0.6 0.5 0.8 1.5 1.8 0.9 1.1 2.9 -1.6 2.2 0.1 2.2 2.3 1.5 1.6 -0.9 -0.8 -0.9 2.4 -0.1 2.2 -0.4 0.9 0.1
Triglycerides 2.7 4.4 7.6 2.1 2.1 2.7 2.2 2.1 2.1 2.2 2.8 -2.1 2.3 1.8 2.4 2.3 1.9 2.3 1.3 2.0 2.0 1.9 1.6 2.3 0.7 2.1 2.4
Type 2 Diabetes (T2D) (2012) 0.7 0.8 1.9 1.2 0.6 1.0 0.9 0.8 0.6 0.8 -0.1 -1.3 -0.0 1.1 -0.2 0.3 0.7 0.8 1.3 1.1 0.3 1.1 1.1 1.2 -1.4 0.3 0.6
Ulcerative Colitis 0.3 0.4 2.2 -1.1 -0.3 -0.6 -0.1 -0.0 -0.3 -0.4 -0.2 -0.6 -1.0 -0.3 -0.3 -0.2 -0.6 -0.5 0.5 0.6 -0.8 -1.0 0.2 0.4 -1.5 -0.4 0.2
Blood Eosinophil Count 0.5 3.6 13.3 0.4 1.7 1.6 2.4 2.2 1.5 2.3 2.6 -1.7 1.1 0.7 2.9 2.8 2.4 2.5 0.8 0.5 1.2 3.6 1.1 1.4 1.1 1.4 0.5
Blood Platelet Count 0.1 0.9 4.5 -1.4 1.4 -0.3 0.7 -0.1 1.0 0.7 0.7 0.6 0.4 -0.1 1.4 1.9 0.2 0.1 -0.5 -1.7 0.6 0.6 -0.3 -0.8 2.1 0.6 -0.3
Blood Red Count 0.4 3.9 13.6 0.6 -1.8 -2.4 -1.7 -1.0 -1.6 -2.0 -3.2 1.4 -0.3 -0.8 -3.7 -2.7 -2.2 -2.2 -1.6 -0.4 -1.7 -3.6 -0.7 -1.6 -1.9 -1.9 -1.0
Blood White Count 0.1 0.7 5.2 1.0 0.5 -1.0 0.1 -0.4 0.4 0.2 0.8 0.9 1.4 -0.6 0.9 1.3 -0.5 0.1 -0.5 -1.0 0.6 1.0 -0.3 -0.5 2.3 0.6 0.2
Heel T-Score 3.1 24.9 231.0 -11.8 2.3 3.1 3.2 1.4 2.9 5.9 -0.5 -3.8 -4.4 5.7 -0.7 1.0 1.4 1.3 15.2 5.0 4.3 2.1 5.9 0.4 -0.2 1.5 0.9
BMI 2.7 15.9 28.6 5.3 3.8 4.7 2.9 3.8 3.8 4.5 4.0 -3.0 3.9 4.3 4.0 2.7 2.8 4.3 3.6 4.5 4.3 3.1 4.2 4.2 2.7 4.4 5.1
Height 1.1 20.7 40.8 6.4 5.6 5.9 5.0 3.7 3.9 5.2 4.8 -4.1 5.2 2.5 5.5 5.1 5.2 5.3 1.6 2.9 2.7 6.4 2.5 5.5 0.1 4.1 3.6
Waist Hip Ratio (WHR) 0.1 0.5 6.9 0.7 -0.7 -0.1 -0.1 -0.4 -0.4 -0.7 0.0 -0.1 -0.4 -0.7 0.1 -0.5 -0.4 0.0 -2.6 -0.6 -0.5 0.3 -0.6 0.5 -0.3 0.0 0.1
Systolic Blood Pressure 1.0 5.1 8.9 -2.2 -2.2 -2.2 -2.6 -2.8 -2.2 -2.8 -0.9 2.7 -2.2 -2.8 -1.4 -1.8 -2.7 -2.5 -2.1 -2.2 -2.2 -2.5 -3.0 -2.1 -0.7 -1.8 -1.8
Smoking Status 1.1 2.6 10.9 2.3 0.9 1.3 0.9 1.3 1.0 1.3 3.3 -1.3 1.6 1.0 3.0 1.5 1.1 1.8 0.1 0.6 0.6 2.3 0.7 1.8 1.3 1.6 1.5
Allergy or Eczema 0.8 2.0 5.8 -1.1 1.6 0.5 1.6 1.5 1.6 1.5 2.4 -1.4 0.4 0.7 2.4 2.3 1.3 1.5 1.0 1.1 0.8 0.9 0.8 1.4 1.1 1.8 1.3
Cardiovascular Disease 0.2 0.7 3.2 1.3 -0.7 0.7 -1.1 -0.8 -0.3 -0.5 0.6 0.8 -1.8 -0.6 0.3 -0.5 -1.3 0.3 -0.6 -0.7 -0.1 1.2 -1.1 0.7 0.7 0.5 0.5
Hypothyroidism (self reported) 0.2 0.5 2.5 0.3 0.1 0.9 0.3 0.1 -0.1 0.2 0.2 -0.9 0.1 -0.4 -0.1 0.1 0.2 0.6 0.5 1.6 0.2 1.3 1.1 1.4 -0.4 0.6 1.3
Respiratory disease 0.9 2.1 8.2 0.6 1.0 0.7 1.6 1.8 1.2 1.6 2.3 -1.3 2.1 0.8 2.9 2.0 1.5 1.7 -0.0 0.5 0.8 1.0 0.7 1.5 0.4 1.4 1.4
Type 2 Diabetes (T2D) (2018) 0.5 1.0 3.6 1.4 0.9 1.2 0.3 1.2 0.8 1.5 1.2 -0.3 1.4 1.6 0.9 0.4 0.0 1.2 0.9 -0.0 0.1 1.9 0.4 1.2 0.3 0.7 0.7
Lung FEV1/FVC ratio 0.8 3.8 10.6 -0.8 -2.1 -0.2 -3.0 -3.2 -2.7 -2.5 -1.2 2.5 -1.6 -2.7 -1.3 -2.5 -2.6 -2.1 -2.1 -1.1 -0.8 -0.7 -2.3 -1.3 -0.5 -1.8 -0.9
Lung FVC 0.7 3.7 12.3 -2.0 -1.2 -2.5 -1.4 -1.7 -1.4 -1.8 -3.5 1.2 -2.0 -0.6 -3.0 -2.2 -1.3 -2.4 0.2 -0.3 -1.4 -3.2 -0.7 -2.2 -0.8 -1.8 -2.1
Neuroticism 0.8 2.0 4.8 0.9 2.0 0.1 1.2 1.1 1.7 1.6 1.4 -1.3 0.3 1.0 1.4 1.4 0.7 1.6 0.9 1.3 1.7 1.6 1.5 2.2 1.0 1.8 2.1
Chronotype (morning person) 3.6 8.4 16.1 -2.6 -3.3 -2.2 -4.0 -3.3 -3.5 -3.2 -1.9 3.6 -2.7 -3.0 -2.5 -3.7 -4.0 -3.1 -3.0 -2.2 -1.4 -1.8 -3.1 -2.8 -0.6 -3.1 -2.4
Hair Pigment 0.0 0.6 2.7 -0.2 -0.4 0.0 -0.3 -0.4 0.1 -0.5 0.9 0.6 -1.2 -0.1 0.0 0.3 -0.0 -0.4 -1.2 -1.6 0.2 0.6 -0.4 -1.2 1.6 -0.0 -1.2
Tanning 0.1 1.1 3.0 1.4 -0.7 -0.6 -1.0 -1.7 -1.1 -1.5 -1.6 0.8 -0.1 -1.4 -1.4 -1.4 -1.0 -1.2 -1.0 -0.1 -0.6 -0.7 -0.8 -0.9 -0.0 -1.1 -0.8
Hand grip strength (left) 1.1 3.0 7.7 -0.4 -1.8 -2.0 -1.7 -2.7 -1.8 -2.3 -2.8 1.4 -1.0 -2.0 -2.6 -2.1 -2.1 -2.2 -1.8 -0.9 -0.1 -1.0 -0.0 -1.7 0.2 -1.3 -0.8
Number of treatments/medications taken 0.4 0.7 2.0 -0.4 -0.8 -0.7 -0.6 -1.1 -1.2 -0.7 0.2 0.4 -0.9 -1.1 -0.0 -0.6 -0.8 -0.8 -0.6 -1.1 -1.3 0.0 -1.0 0.0 -1.4 -1.1 -0.8
Average weekly spirits intake 1.9 2.4 7.6 2.4 1.5 1.2 1.2 1.3 1.6 1.4 -0.1 -1.5 1.1 1.6 0.1 0.6 1.4 1.6 2.0 2.0 1.5 1.4 2.8 1.5 1.2 1.4 1.9
Sensitivity / hurt feelings 0.2 0.3 1.4 0.6 0.9 -0.5 0.4 0.6 0.7 0.6 0.4 -0.2 1.2 0.6 0.5 0.7 -0.1 0.3 0.3 0.6 0.4 0.4 0.3 0.8 -0.0 0.5 0.9
Frequency of depressed mood in last 2 weeks 0.2 0.2 1.2 0.5 -0.4 -0.3 -0.5 -0.8 -0.2 -0.4 -0.6 0.3 -0.1 -0.3 -0.2 -0.5 -1.0 -0.2 0.2 -0.7 0.1 1.1 -0.1 0.3 -0.7 -0.2 -0.1
Hearing difficulty/problems: Yes 0.6 0.8 1.9 0.4 -1.0 -1.0 -1.2 -1.0 -1.4 -1.0 -1.2 0.8 -0.5 -0.8 -1.1 -1.3 -1.2 -1.1 -0.1 0.4 -0.8 -0.4 -0.7 -0.6 -0.7 -1.1 -0.7
Relative age of first facial hair 0.2 0.5 2.0 -0.1 0.5 0.5 0.4 0.1 0.3 0.5 0.8 -0.5 -0.6 0.2 0.8 0.7 0.1 0.6 0.8 0.5 0.8 1.4 0.4 1.4 0.3 0.7 1.0
Other serious medical condition/disability diagnosed by doctor 6.9 9.0 18.9 -1.6 -3.4 -3.0 -3.3 -3.2 -3.7 -3.1 -3.4 2.2 -2.7 -3.6 -3.2 -3.6 -2.8 -2.7 -2.1 -2.4 -4.3 -0.9 -2.4 -0.8 -4.3 -3.2 -2.5
Ever used hormone-replacement therapy (HRT) 0.4 0.5 3.3 0.6 -0.3 -0.4 -0.1 -0.8 0.2 -1.1 -0.3 0.0 -0.9 -1.0 -0.5 0.2 0.2 -0.6 0.7 0.9 0.9 -0.2 0.2 -0.6 1.8 0.6 0.4
Ever had hysterectomy (womb removed) 0.3 0.4 2.0 1.2 -0.2 0.3 0.2 -0.6 -0.2 -0.2 -0.1 -0.4 -0.3 -0.2 -0.8 -0.2 -0.1 -0.2 0.3 0.0 -0.5 1.4 0.3 1.0 -1.4 0.1 0.3
Systolic blood pressure, automated reading 0.1 0.4 2.4 -0.5 -0.6 -0.5 -0.7 -1.3 -0.5 -1.0 0.3 0.6 -0.1 -1.6 -0.1 -0.2 -0.6 -0.7 -0.0 -0.2 -0.6 -0.8 -0.6 -0.4 -0.4 -0.0 -0.2
Eye problems/disorders: Diabetes related eye disease 3.0 3.3 6.8 -1.3 -2.6 -2.2 -2.4 -2.6 -2.0 -2.5 -2.3 1.8 -2.2 -2.6 -2.0 -2.1 -2.0 -1.5 -1.4 -1.2 -1.0 -0.7 -0.9 -1.2 0.0 -1.0 -1.0
Angina 0.3 0.3 1.7 -0.9 -0.2 -0.9 -0.1 -0.6 0.0 -0.3 0.4 0.2 -1.1 -1.3 0.5 0.5 -0.3 0.0 -0.6 -0.8 -0.5 0.4 -0.3 0.1 0.6 0.2 -0.3
Medication for hormone replacement therapy 0.3 0.3 3.0 -0.6 -0.1 -0.3 -0.0 0.1 -0.0 -0.5 -0.6 0.0 -1.2 0.4 -0.9 -0.1 0.2 -0.7 0.1 0.2 0.2 -1.7 -0.0 -0.9 -0.2 -0.2 -0.4
Vitamin and mineral supplements 1.0 1.4 4.7 -0.1 -1.8 -1.6 -1.2 -1.3 -1.2 -1.7 -0.9 0.8 -1.6 -1.3 -2.2 -1.3 -1.3 -1.2 -0.8 -0.7 -0.6 -0.3 0.1 -0.7 -0.9 -0.9 -0.4
Supplements: Zinc 0.2 0.2 0.8 -0.1 0.7 0.4 0.6 0.5 0.5 0.5 0.0 -0.2 0.6 0.1 0.5 0.6 0.4 0.4 -0.3 0.4 0.9 -0.0 0.2 -0.0 0.7 0.6 0.4
Medication: Co-codamol 0.3 0.4 1.4 -0.0 0.4 0.0 0.6 -0.5 0.5 0.1 0.7 -0.1 -0.3 -0.5 1.0 1.2 0.5 0.6 -0.5 -0.5 0.2 1.1 0.3 -0.1 1.1 0.9 -0.2
Medication: Metformin 0.3 0.5 1.6 0.1 -0.5 0.0 -0.7 -0.4 -0.9 -0.0 -0.1 0.8 0.6 -0.4 -0.1 -0.9 -1.1 -0.3 -0.8 -1.0 -1.2 0.2 -1.0 0.1 -1.3 -0.8 -0.3
Diabetes (father) 0.4 0.5 4.8 0.6 -0.4 0.6 0.2 -0.1 -0.4 0.1 -1.3 -0.6 -0.5 0.1 -1.0 -0.8 -0.1 0.2 0.3 0.7 -0.4 0.1 0.8 0.9 -2.2 -0.3 0.3
Diabetes (mother) 0.1 0.1 0.7 0.4 -0.3 -0.2 -0.3 -0.4 -0.4 -0.1 0.1 0.1 0.7 -0.5 0.2 -0.5 -0.7 0.0 -0.3 0.3 0.3 -0.3 0.0 0.5 -0.2 0.1 0.8
Severe depression (siblings) 0.7 0.8 3.3 0.9 0.1 1.6 1.0 0.8 0.5 0.1 -0.1 -1.5 -0.1 1.2 -0.3 0.1 0.7 0.5 0.7 1.3 0.5 0.1 0.9 1.3 -1.8 0.4 0.9
Pack years adult smoking proportion 0.6 0.9 2.4 1.1 -1.1 -0.9 -1.2 -1.0 -1.0 -0.7 -0.5 1.3 1.2 -1.1 -0.4 -0.9 -1.4 -0.6 -1.1 -1.6 -0.5 -0.0 -0.8 -0.6 0.2 -1.0 -0.6
Impedance of leg (right) 0.3 1.4 5.4 -1.6 -1.2 -1.5 -0.6 -0.5 -1.0 -1.1 -0.6 0.3 0.8 -1.3 -0.5 -0.4 -0.4 -0.9 -1.9 -1.5 -2.3 -0.4 -1.3 -0.9 -1.1 -1.2 -2.2
Leg fat-free mass (left) 2.1 11.2 24.4 4.9 3.6 4.4 3.0 2.9 2.8 3.8 3.1 -2.6 2.9 2.8 3.4 2.7 2.8 3.8 2.5 3.4 3.4 3.5 2.9 4.1 1.2 3.4 4.2
Trunk fat percentage 3.0 12.0 32.0 5.7 2.8 3.6 2.7 3.1 2.8 3.5 3.5 -2.9 4.1 2.9 3.3 2.5 2.7 3.9 2.3 3.9 3.2 3.9 3.6 4.4 1.5 3.6 4.3
Hand grip strength (right) 1.4 3.8 8.5 -1.0 -2.1 -1.8 -2.0 -2.9 -2.3 -2.3 -2.0 2.1 -1.2 -2.6 -1.7 -2.0 -2.5 -2.4 -2.9 -1.9 -0.8 -1.1 -1.4 -1.7 0.1 -1.6 -1.2
Townsend deprivation index at recruitment 3.5 4.9 10.4 2.7 1.8 2.5 2.1 2.3 2.1 2.3 3.2 -2.5 2.2 2.2 2.5 1.8 1.4 2.6 0.9 1.8 1.4 2.0 1.9 3.2 0.2 2.4 2.8
Current tobacco smoking 0.4 0.7 2.5 1.5 -0.9 0.1 -0.7 -0.3 -0.4 -0.3 1.4 0.8 1.2 -0.1 0.9 -0.2 -0.7 -0.2 -1.6 -1.5 -0.4 0.7 -0.9 -0.1 0.8 -0.1 -0.1
Average weekly fortified wine intake 1.4 1.6 5.0 0.2 -1.3 -0.9 -1.4 -1.3 -1.4 -1.4 -2.1 1.1 -0.8 -0.5 -1.7 -2.2 -0.8 -1.4 -0.0 -0.5 -1.3 -1.2 -0.8 -1.1 -1.1 -1.5 -1.6
Maternal smoking around birth 0.8 1.1 4.8 -0.9 -0.1 -1.1 -1.0 -0.4 -0.6 -0.4 -0.2 1.2 -0.9 0.0 0.1 -0.5 -0.9 -1.0 -1.2 -1.7 -1.3 -2.0 -2.2 -1.1 -0.1 -0.9 -1.2
Fed-up feelings 0.2 0.4 1.1 0.8 0.5 0.2 0.4 -0.1 0.4 0.3 0.7 -0.4 1.1 0.2 0.4 0.5 0.2 0.5 0.4 0.5 0.8 1.0 0.6 1.0 0.1 0.7 1.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.7 0.9 2.3 0.8 -0.8 -1.0 -1.0 -1.4 -0.9 -1.2 -1.5 1.0 -0.5 -0.5 -1.4 -1.3 -1.2 -1.0 0.2 -0.7 -0.7 0.1 -0.3 -0.4 -1.2 -0.9 -0.8
Relative age voice broke 0.4 0.6 2.8 0.8 0.9 0.8 0.6 0.3 0.3 0.8 0.8 -0.5 0.7 0.7 0.9 0.5 0.5 0.9 0.5 0.1 0.4 1.7 0.5 1.5 -0.3 0.4 1.0
Taking other prescription medications 0.6 0.9 2.1 -0.6 -1.2 -1.5 -0.5 -1.0 -1.2 -1.2 -0.7 0.5 -0.3 -1.5 -0.8 -0.4 -0.7 -1.1 -1.3 -1.0 -1.2 -0.5 -0.7 -0.4 -0.8 -1.0 -0.9
Age when periods started (menarche) 1.0 2.4 5.7 -1.5 -1.5 -1.2 -1.6 -1.4 -1.9 -1.5 -2.1 1.3 -1.4 -1.0 -2.4 -1.7 -1.2 -1.8 -1.6 -1.2 -1.3 -1.2 -1.0 -1.5 -1.4 -1.9 -1.6
Bilateral oophorectomy (both ovaries removed) 0.3 0.4 1.0 0.7 0.2 0.3 0.7 -0.2 0.4 -0.1 0.6 -0.8 0.0 -0.5 0.5 0.8 0.6 0.3 0.3 1.0 0.4 0.5 0.7 0.9 -0.2 0.9 1.0
Heel bone mineral density (BMD) T-score, automated (left) 1.6 3.7 31.1 -4.9 1.1 1.2 1.3 -0.1 0.7 2.3 -0.4 -1.5 -2.3 1.4 -0.5 0.5 0.7 0.3 5.6 2.1 1.0 1.1 2.4 0.3 -1.0 0.5 0.3
Tinnitus: Yes, but not now, but have in the past 0.1 0.1 0.6 -0.3 -0.1 -0.1 0.5 0.5 0.4 0.2 -0.0 -0.8 0.4 0.1 0.1 0.2 0.5 0.4 -0.5 -0.2 0.0 0.3 0.7 0.3 0.3 0.3 -0.3
Qualifications: CSEs or equivalent 0.2 0.2 1.1 -0.4 0.3 -0.2 -0.2 -0.2 -0.0 -0.2 -1.0 0.4 -0.9 0.5 -0.5 -0.2 -0.4 -0.3 0.2 -0.2 0.2 -0.7 -0.9 -0.2 0.0 -0.2 0.1
Serious illness, injury or assault to yourself 3.2 3.9 8.1 0.4 -2.5 -0.4 -2.3 -2.0 -2.4 -2.2 -2.6 1.5 -1.2 -2.4 -2.4 -2.9 -1.8 -1.7 -2.1 -1.9 -2.4 -0.3 -1.8 -0.5 -2.7 -2.1 -1.5
High blood pressure 0.6 1.8 4.8 0.8 -2.0 -0.1 -2.2 -1.8 -1.7 -1.4 0.4 1.6 -1.6 -1.6 0.1 -1.7 -2.1 -0.7 -1.4 -1.4 -1.1 0.5 -2.0 -0.2 -0.4 -0.7 -0.5
Hayfever, allergic rhinitis or eczema 0.8 1.8 4.4 -0.4 1.8 1.3 1.3 1.8 1.4 1.7 2.1 -0.9 0.6 1.5 2.0 1.7 1.4 1.5 1.4 1.1 1.1 0.6 0.5 0.7 0.9 1.3 1.0
Multivitamins +/- minerals 0.9 1.1 4.3 -0.0 1.3 2.0 1.1 1.4 1.1 1.4 1.2 -0.8 1.2 1.5 2.1 1.0 1.0 1.0 0.5 0.5 0.4 -0.0 -0.2 0.3 0.3 0.5 0.0
Stomach or abdominal pain in last month 0.7 0.9 4.0 1.3 0.7 1.2 0.2 0.9 0.2 1.1 0.7 -0.5 0.2 0.9 0.7 -0.1 -0.0 1.1 1.2 0.8 -0.0 2.0 0.5 1.9 -1.3 0.2 1.1
Supplements: Glucosamine 0.5 0.6 3.6 0.4 -0.5 -0.1 -0.3 -0.4 -0.7 -0.5 -1.9 0.1 -0.7 -0.2 -1.3 -1.3 0.0 -0.7 0.6 0.7 -0.6 -1.0 0.3 -0.7 -1.4 -0.9 -0.6
Diverticular disease/diverticulitis (self-reported) 2.7 3.2 8.9 1.4 1.4 1.4 1.2 1.6 1.6 1.9 1.7 -1.6 0.9 1.5 1.7 1.2 0.7 2.1 1.0 1.8 2.0 2.6 2.1 2.7 1.3 2.2 3.0
Medication: Atenolol 0.5 0.6 1.9 1.1 0.3 1.1 0.8 -0.0 0.6 0.2 1.0 -0.7 0.1 0.1 0.7 0.5 0.5 0.6 0.9 0.4 1.4 1.3 0.6 0.4 1.0 0.8 0.6
Medication: Levothyroxine sodium 0.3 0.5 2.1 0.6 -0.2 0.8 -0.1 0.3 -0.3 0.2 0.5 -0.7 0.1 -0.2 -0.2 -0.4 -0.2 0.4 0.8 1.4 -0.2 1.3 0.8 1.4 -0.9 0.2 1.1
Sitting height 1.1 7.8 19.2 3.9 3.4 3.3 2.7 2.0 2.3 3.6 2.8 -1.9 4.0 1.5 3.3 3.0 2.8 3.2 2.1 1.3 2.2 4.4 1.9 2.6 1.7 2.5 1.9
Chronic bronchitis/emphysema (father) 1.3 1.6 2.7 -0.9 -1.4 -1.2 -1.2 -1.1 -1.6 -1.3 -0.7 1.0 -0.8 -0.8 -1.2 -1.3 -1.5 -1.4 -1.3 -1.4 -1.3 -1.4 -1.5 -0.7 -1.6 -1.6 -1.1
High blood pressure (mother) 0.2 0.3 2.1 0.3 0.3 0.9 0.1 0.2 0.1 0.7 0.3 -0.6 -0.2 0.1 0.9 -0.1 0.1 0.7 0.4 0.5 0.1 0.5 0.4 1.4 -1.0 0.4 0.9
Body mass index (BMI) 2.3 9.7 23.5 4.8 2.4 4.0 2.2 2.8 2.3 3.2 3.1 -2.5 2.8 3.1 2.7 1.5 1.9 3.3 2.9 4.0 3.3 2.7 3.4 4.0 0.9 3.1 4.5
Impedance of leg (left) 0.3 1.2 4.2 -1.9 -1.0 -1.6 -0.5 -0.5 -0.7 -1.0 -0.7 0.3 0.3 -1.2 -0.7 -0.2 -0.5 -0.9 -1.7 -1.4 -1.8 -0.4 -1.0 -1.1 -0.7 -1.0 -2.1
Leg predicted mass (left) 2.1 11.0 24.6 5.0 3.6 4.3 3.0 2.8 2.8 3.7 3.0 -2.6 2.9 2.8 3.3 2.7 2.7 3.8 2.5 3.4 3.4 3.5 2.9 4.1 1.1 3.4 4.2
Trunk fat mass 3.9 16.9 38.9 6.2 3.6 4.8 3.5 3.8 3.4 4.3 4.2 -3.6 4.4 3.4 4.0 3.1 3.3 4.7 2.9 4.6 3.8 4.6 4.2 5.2 1.5 4.2 5.0
Waist circumference 3.6 13.3 34.8 5.9 2.9 4.5 2.8 3.1 2.8 3.6 3.5 -3.2 3.2 3.2 3.3 2.2 2.6 4.1 2.8 4.4 3.6 3.9 3.7 5.0 0.8 3.8 5.1
Number of incorrect matches in round 2.1 3.5 6.8 -1.4 -1.9 -2.0 -1.8 -2.1 -1.6 -2.6 -1.9 2.0 -2.2 -1.6 -1.9 -1.7 -1.6 -2.2 -1.4 -1.8 -1.6 -2.2 -1.8 -2.5 -0.1 -2.0 -2.0
Past tobacco smoking 3.1 5.7 15.1 -1.6 -2.0 -2.6 -2.2 -2.4 -2.0 -2.4 -3.9 2.7 -1.6 -2.2 -3.6 -2.3 -2.3 -2.9 -1.9 -1.8 -0.8 -3.2 -1.5 -3.2 -0.5 -2.3 -2.3
Alcohol usually taken with meals 1.4 2.3 8.1 -0.5 -1.6 -1.1 -1.6 -2.2 -1.5 -2.0 -2.8 1.4 -2.2 -2.1 -2.6 -1.8 -0.9 -1.5 -0.9 -0.6 -0.1 -0.8 -0.6 -1.4 -0.1 -1.0 -0.8
Nervous feelings 1.5 2.8 7.1 1.4 2.0 1.1 1.9 1.8 1.8 2.2 2.2 -1.9 1.6 1.2 2.1 1.9 1.6 2.0 1.0 0.1 0.8 2.7 0.6 2.4 0.3 1.3 1.1
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.2 1.0 -0.1 -0.4 -0.6 -0.4 -0.2 0.0 -0.4 -0.5 -0.1 -1.0 -0.0 -0.2 -0.0 -0.5 0.1 -0.7 -0.2 0.6 -0.3 0.3 0.1 -0.3 0.2 0.5
Hearing difficulty/problems with background noise 0.4 0.7 4.7 0.7 -0.1 0.6 -0.4 -0.3 -0.7 0.1 -0.5 -0.4 -0.5 -0.2 -0.7 -1.3 -0.3 0.1 1.4 1.4 -0.3 0.4 0.4 1.4 -2.2 -0.3 1.0
Hair/balding pattern: Pattern 2 0.4 0.5 2.5 0.0 -0.4 -0.1 0.2 -0.2 -0.1 -0.5 -0.4 -0.5 -1.5 -1.4 0.0 0.3 0.3 0.3 -1.6 -0.8 -0.6 1.0 0.3 1.0 -0.6 0.3 0.6
Had menopause 1.2 1.4 5.8 1.3 0.7 0.7 1.1 0.9 1.1 1.0 1.3 -1.5 0.7 -0.1 0.9 1.2 1.2 1.4 0.9 1.0 0.9 2.4 1.1 1.7 1.1 1.5 1.2
Had other major operations 0.8 1.0 5.4 1.8 1.1 1.4 0.6 0.4 0.1 1.1 0.8 -0.6 2.3 0.7 0.7 -0.1 0.5 0.7 0.3 0.8 0.1 1.3 0.1 1.5 -1.1 0.1 1.1
Forced vital capacity (FVC) 0.2 0.9 4.3 1.2 2.1 1.0 1.3 0.5 1.1 1.1 -0.0 -0.9 1.5 1.0 0.5 0.8 1.2 0.7 0.8 1.1 0.7 0.1 0.6 0.6 0.5 0.8 0.4
Heel bone mineral density (BMD) T-score, automated (right) 2.5 5.8 39.4 -4.6 1.8 2.1 2.2 0.8 1.4 3.3 0.4 -2.5 -1.1 2.3 0.1 1.2 1.6 1.1 6.3 3.1 2.0 1.8 3.5 1.0 -0.9 1.2 1.2
Ever unenthusiastic/disinterested for a whole week 2.6 3.1 7.8 -1.5 -1.9 -1.3 -2.4 -1.8 -2.1 -1.7 -1.3 2.0 -2.4 -1.2 -1.7 -2.2 -2.8 -2.0 -1.0 -1.0 -1.1 -1.4 -1.5 -1.4 -1.6 -2.1 -1.3
Qualifications: None of the above 0.4 0.9 3.3 1.8 1.1 0.9 1.1 0.9 1.0 1.0 0.8 -0.6 1.1 1.4 0.9 0.9 0.7 0.7 1.0 0.8 0.5 0.1 0.5 1.0 0.2 1.0 1.1
Financial difficulties in last 2 years 0.9 1.2 5.3 1.9 0.8 2.3 0.9 1.6 0.9 1.0 0.9 -1.3 0.7 1.2 1.1 0.4 0.8 1.2 0.0 0.9 1.1 0.2 0.8 1.1 -0.3 0.8 1.0
Mouth/teeth dental problems 0.2 0.3 1.4 -0.1 0.3 0.2 0.2 0.6 0.3 0.6 0.2 -0.3 -0.3 0.6 0.3 0.3 0.6 0.6 0.6 0.3 1.2 0.6 0.8 0.3 0.2 0.5 0.5
Heart attack 0.5 0.6 1.7 0.8 1.2 0.1 1.0 0.8 1.0 0.9 0.2 -1.3 0.5 1.1 0.2 0.8 1.0 0.7 0.8 0.4 0.5 0.6 1.3 0.8 -0.1 0.6 0.3
Allergy 0.7 1.7 4.2 -0.5 -1.4 -1.0 -1.2 -1.8 -1.2 -1.7 -1.8 1.0 -0.9 -1.4 -2.1 -1.5 -1.1 -1.6 -1.1 -1.3 -1.3 -1.0 -0.7 -1.2 -0.2 -1.2 -1.5
Pain all over the body in last month 0.4 0.4 1.5 -0.1 0.2 0.6 -0.4 -0.2 -0.2 -0.2 -0.6 0.7 -0.5 0.9 -1.1 -0.9 -0.6 -0.8 0.6 -0.2 -1.2 -0.8 -0.8 -0.6 -0.6 -0.7 -0.9
Diabetes (self-reported) 0.8 1.3 4.4 1.8 1.7 1.2 1.0 1.2 1.2 1.8 0.6 -0.5 1.5 2.1 0.7 0.6 0.5 1.1 1.7 0.6 0.3 0.8 0.4 1.2 -0.3 0.7 0.7
Hayfever/allergic rhinitis (self-reported) 0.2 0.2 0.6 -0.8 0.4 0.0 0.6 0.5 0.5 0.2 0.5 -0.1 -0.2 0.1 0.3 0.7 0.8 0.0 -0.3 -0.4 -0.6 -0.6 -0.5 -0.6 0.0 0.0 -0.6
Medication: Ramipril 0.6 0.7 1.8 -0.1 -0.8 -1.0 -1.2 -0.9 -1.0 -0.8 -0.7 1.0 0.3 -1.1 -0.2 -0.8 -1.3 -0.4 -1.1 -1.0 -1.2 -0.2 -0.9 -0.4 -0.5 -0.6 -0.7
Medication: Simvastatin 0.2 0.4 1.9 0.4 -0.2 -0.7 -0.1 -0.6 0.3 -0.5 0.9 0.4 0.1 -1.2 0.2 0.7 0.3 0.1 -0.7 -1.0 -0.1 0.0 -0.1 -0.6 1.4 0.5 -0.4
Fluid intelligence score 3.0 6.2 8.8 2.5 2.6 2.0 2.7 2.7 2.6 2.8 2.8 -2.6 1.6 1.6 2.8 2.9 2.6 2.9 1.6 1.9 2.3 3.0 2.3 2.7 1.8 2.9 2.8
Illnesses of siblings 0.3 0.5 1.8 -0.0 0.7 -0.1 0.9 0.8 0.6 0.6 -0.1 -0.8 0.9 1.4 -0.0 0.2 0.6 0.3 1.2 0.9 -0.4 -1.0 0.5 0.0 -1.2 -0.1 -0.2
Neuroticism score 0.7 1.4 3.3 0.8 1.5 0.3 1.1 0.9 1.5 1.3 1.2 -1.1 0.4 0.8 1.3 1.3 0.6 1.4 0.8 0.9 1.4 1.5 0.9 1.8 0.9 1.6 1.8
Weight 3.8 18.7 41.8 6.5 4.0 5.6 3.6 3.7 3.4 4.7 4.3 -3.7 4.1 3.5 4.3 3.2 3.4 4.9 3.1 4.6 4.2 5.0 4.2 5.6 1.4 4.4 5.5
Impedance of arm (right) 0.2 0.9 2.6 -1.2 -0.4 -1.6 -0.0 -0.5 -0.5 -0.7 -0.5 0.1 0.9 -1.4 0.0 0.7 0.1 -0.3 -1.5 -1.6 -1.5 0.8 -1.4 -0.4 -0.2 -0.6 -1.6
Arm fat percentage (right) 2.3 9.2 22.8 4.8 2.5 3.5 2.3 2.7 2.2 3.2 3.1 -2.5 3.5 2.8 3.0 1.9 2.2 3.4 2.5 3.6 2.7 3.0 2.8 4.1 0.9 3.0 4.0
Trunk fat-free mass 1.3 7.7 17.8 3.9 3.2 4.2 2.6 2.5 2.3 3.4 3.0 -2.1 2.5 2.3 3.1 2.4 2.4 3.2 1.7 2.4 2.3 2.8 2.0 3.4 0.5 2.8 3.3
Hip circumference 3.4 14.7 36.8 6.1 3.6 5.2 3.0 3.3 3.0 4.0 3.3 -3.1 3.5 3.3 3.3 2.5 2.9 4.2 3.8 4.6 4.0 3.9 3.8 4.8 0.8 3.7 5.0
Time employed in main current job 0.5 0.6 2.2 -1.0 -0.0 -0.3 -0.4 -1.0 -0.5 -0.3 0.5 1.2 -0.4 -1.0 0.8 0.2 -0.3 -0.6 -1.0 -1.3 -1.0 -0.1 -1.5 -0.8 0.5 -0.4 -0.8
Alcohol intake versus 10 years previously 0.9 1.3 4.5 1.9 1.3 0.9 1.0 1.0 0.7 1.4 1.6 -1.1 2.1 0.9 1.6 0.9 0.9 1.4 -0.1 0.4 0.4 1.0 0.3 1.7 -0.3 0.7 1.3
Father’s age at death 1.2 1.6 4.1 -0.3 1.2 1.1 1.5 2.0 1.4 1.6 1.8 -1.6 1.0 0.8 1.6 1.6 1.2 1.7 1.3 0.8 0.3 0.9 0.9 1.3 -0.5 1.0 0.8
Worrier / anxious feelings 0.3 0.6 2.7 -1.1 0.9 -1.3 0.4 -0.2 0.8 0.3 0.8 -0.1 0.0 -0.2 1.3 1.1 -0.4 0.2 0.3 0.1 0.5 -0.2 -0.6 0.6 1.6 0.9 0.8
Frequency of tiredness / lethargy in last 2 weeks 1.2 1.9 4.5 -0.0 -1.2 -1.5 -1.5 -1.1 -1.3 -1.4 -2.1 1.5 -1.0 -1.0 -1.4 -1.4 -1.8 -1.2 -2.0 -1.6 -1.4 -0.7 -1.7 -0.8 -1.1 -1.4 -1.1
Falls in the last year 0.2 0.3 1.9 1.2 -0.2 0.5 -0.4 -0.4 -0.1 0.1 0.1 0.2 -0.3 -0.5 0.4 -0.1 0.0 0.2 -0.8 -0.2 0.2 1.4 0.3 0.2 0.9 0.3 0.1
Hair/balding pattern: Pattern 3 0.2 0.3 1.8 -0.6 -0.3 0.1 -0.4 -0.2 -0.4 -0.2 -0.5 0.1 -1.0 0.3 -0.9 -0.8 -0.2 -0.4 1.3 0.6 0.4 -0.0 0.4 -0.4 -0.2 -0.5 -0.3
Number of live births 1.5 2.1 5.2 1.8 1.2 1.9 2.0 1.7 1.5 1.2 1.4 -2.2 0.8 2.0 1.2 1.4 2.3 1.7 1.1 1.0 1.0 0.7 1.4 1.2 -0.6 1.2 1.0
Forced expiratory volume in 1-second (FEV1) 0.1 0.2 1.7 0.7 1.3 0.8 0.3 -0.4 0.2 0.4 -0.3 -0.0 1.1 0.2 0.3 0.0 0.3 0.1 -0.1 0.6 0.4 -0.3 -0.3 0.1 0.4 0.1 0.2
Pulse rate 1.3 2.3 9.4 -0.1 -1.0 -1.2 -1.6 -0.9 -1.0 -1.1 -3.1 1.3 -1.5 0.2 -2.5 -2.3 -1.8 -1.6 -0.9 -0.6 -1.3 -2.3 -0.8 -1.2 -1.6 -1.4 -0.8
Happiness 2.8 3.4 8.0 -1.7 -2.3 -1.4 -2.6 -2.7 -2.5 -2.1 -1.5 2.3 -1.5 -2.8 -1.5 -2.1 -2.2 -1.7 -2.1 -1.5 -0.8 -0.3 -1.8 -0.9 -0.5 -1.5 -0.5
Noisy workplace 0.4 0.4 1.4 -0.2 -0.8 -0.6 -0.7 -0.9 -0.5 -1.2 -0.6 0.1 -0.3 -0.6 -1.2 -0.9 -0.8 -0.8 -0.2 0.6 -0.2 -1.1 0.3 -0.4 -0.5 -0.3 -0.0
Qualifications: A levels/AS levels or equivalent 0.3 0.6 3.5 -1.0 -1.0 -0.0 -0.7 -1.3 -1.1 -0.9 -0.3 0.6 -0.6 -1.9 -0.4 -0.5 -0.3 -0.1 -1.3 -0.3 -0.1 1.1 0.3 0.1 -0.1 -0.2 0.1
Serious illness, injury or assault of a close relative in last 2 years 2.1 2.4 5.5 -0.5 -1.4 -1.5 -1.9 -1.7 -1.2 -1.9 -1.5 2.0 -2.2 -1.6 -1.5 -1.4 -1.1 -1.6 -2.2 -1.2 0.2 -1.7 -0.9 -2.4 1.3 -1.0 -1.0
Mouth/teeth dental problems: Dentures 0.5 0.8 2.1 1.0 1.0 0.7 1.3 0.5 1.2 0.6 1.4 -1.2 1.1 0.4 0.8 1.3 0.8 0.6 0.2 0.5 0.4 0.3 1.0 0.5 1.1 1.2 1.1
Asthma 0.7 1.4 3.1 1.2 0.4 1.1 0.9 1.4 0.6 1.3 1.6 -1.0 1.6 0.5 1.8 1.1 0.8 1.6 -0.0 0.8 1.1 1.7 1.1 1.8 -0.0 1.1 1.7
Medication: Ibuprofen (e.g. Nurofen) 0.7 0.9 3.3 0.0 -0.9 -0.1 -1.4 -0.8 -1.1 -0.8 -0.9 1.4 -0.8 -0.3 -0.7 -1.5 -0.9 -0.9 -1.8 -1.3 -0.0 -0.3 -1.3 -1.0 -0.0 -1.1 -0.8
Medication: Cholesterol lowering 0.3 0.5 2.0 0.6 0.8 -0.1 0.6 0.1 0.4 0.6 1.4 -0.5 0.8 -0.2 0.9 0.7 0.5 0.8 0.3 -0.4 -0.6 1.2 0.1 1.1 0.0 0.7 0.4
Depression (self-reported) 0.2 0.2 2.1 1.5 0.1 -0.2 -0.2 0.2 0.1 0.3 -0.2 0.1 0.7 0.1 -0.7 0.1 -0.4 0.1 -0.2 -0.2 0.4 0.6 0.7 0.5 0.1 0.1 0.2
Medication: Lansoprazole 0.5 0.6 1.4 1.0 -0.9 -0.8 -0.6 -0.5 -0.9 -0.5 -0.8 0.2 -0.9 -0.7 -1.2 -1.1 -0.7 -0.5 -0.3 -0.8 -0.9 0.3 -0.1 0.5 -1.2 -0.9 -0.5
Prospective memory result 0.5 0.6 2.4 -1.4 -0.1 -0.6 0.7 -0.3 0.4 -0.3 1.5 -0.7 0.5 -0.6 1.6 1.5 0.5 0.4 -0.5 0.1 0.1 0.1 0.3 1.0 0.4 1.1 0.8
Lung cancer (father) 0.4 0.4 2.1 0.7 -0.0 -0.4 0.2 0.6 0.1 0.4 1.4 -0.1 0.7 0.2 0.7 0.5 0.3 0.5 -1.2 -0.8 -0.4 1.4 -0.1 0.3 0.9 0.1 -0.3
Illnesses of mother 0.4 0.4 2.6 -0.4 -0.8 -0.3 -0.6 -0.2 -0.9 -0.6 -0.7 0.1 -0.5 -0.2 -1.1 -0.9 -0.9 -0.7 0.1 0.2 -0.5 -0.4 -0.2 -0.1 -1.6 -0.9 -0.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.3 2.1 0.6 1.4 0.7 0.3 -0.1 0.2 0.6 -0.4 0.0 1.1 0.5 0.1 -0.1 0.2 0.0 0.5 1.1 0.5 -0.7 -0.4 0.3 -0.0 0.1 0.4
Pulse wave Arterial Stiffness index 3.5 4.1 7.1 1.5 1.5 2.0 2.2 2.0 2.1 2.0 2.2 -2.2 2.0 1.1 1.8 1.9 2.0 2.3 1.6 2.2 1.9 1.9 2.2 2.7 0.8 2.5 2.6
Impedance of arm (left) 0.1 0.6 2.9 -0.7 -0.4 -1.7 -0.0 -0.5 -0.3 -0.8 -0.9 -0.1 0.5 -1.2 -0.4 0.4 0.2 -0.2 -1.2 -1.1 -1.0 1.0 -0.7 -0.5 0.1 -0.4 -1.4
Arm fat mass (right) 3.2 13.1 32.4 5.7 3.2 4.6 2.8 3.2 2.8 3.9 3.5 -2.9 3.7 3.3 3.4 2.3 2.8 4.1 2.9 4.1 3.3 3.9 3.4 4.8 1.1 3.6 4.7
Trunk predicted mass 1.4 7.9 18.1 3.9 3.3 4.3 2.6 2.5 2.3 3.5 3.0 -2.2 2.5 2.4 3.1 2.4 2.4 3.3 1.8 2.4 2.3 2.9 2.1 3.5 0.5 2.8 3.3
Standing height 0.9 9.3 27.8 3.9 3.6 3.7 3.2 2.3 2.5 3.5 2.9 -2.7 3.2 1.1 3.7 3.5 3.1 3.8 0.5 1.5 2.0 5.3 2.0 3.7 1.0 3.0 2.5
Length of working week for main job 0.2 0.2 1.2 -0.1 0.3 0.0 0.1 0.4 0.2 0.6 0.6 -0.5 -0.3 0.5 0.2 0.2 -0.4 0.3 -1.1 -0.3 0.4 0.2 0.7 0.7 0.7 0.5 0.9
Exposure to tobacco smoke at home 0.4 0.4 1.4 0.9 -0.5 0.3 -0.1 -0.1 0.0 -0.2 -0.1 -0.7 -1.0 0.1 -0.8 -0.5 -0.5 0.2 -0.3 1.1 1.2 0.3 1.1 0.8 -0.6 0.5 1.1
Breastfed as a baby 0.1 0.2 0.6 0.7 -0.1 0.4 -0.4 -0.2 -0.2 -0.3 -0.5 0.6 0.5 0.2 -0.4 -0.6 0.1 -0.2 -0.7 -0.5 -0.5 0.2 -0.0 -0.3 -0.1 -0.2 -0.4
Tense / ‘highly strung’ 3.5 5.8 10.0 1.3 2.7 0.9 2.4 2.7 2.8 2.9 2.1 -2.7 1.5 2.2 2.1 2.1 1.4 2.8 2.8 3.0 2.6 1.7 2.9 3.1 1.3 2.8 3.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.3 1.8 0.1 0.2 0.3 -0.1 0.0 0.1 0.3 1.1 -0.5 -0.0 0.1 0.8 0.0 -0.7 0.4 0.4 0.6 -0.1 0.1 0.1 1.2 -1.4 -0.1 0.7
Hair/balding pattern: Pattern 4 0.3 0.7 3.4 -0.0 1.3 0.7 1.0 0.8 1.1 1.3 0.8 -0.6 1.2 1.7 0.5 0.5 0.7 0.4 1.8 0.7 0.2 -0.1 0.4 0.4 0.1 0.4 -0.0
Birth weight of first child 2.5 4.6 8.0 -2.2 -2.8 -1.5 -2.8 -1.8 -2.4 -2.3 -1.4 2.6 -2.4 -1.7 -1.8 -2.5 -2.3 -2.2 -1.7 -2.5 -2.0 -1.7 -2.1 -2.2 -0.4 -2.3 -2.1
Peak expiratory flow (PEF) 0.1 0.3 2.5 1.6 0.6 0.8 -0.0 -0.3 0.0 0.1 -0.3 0.3 0.9 0.6 0.2 -0.3 0.0 0.2 -0.8 0.6 0.6 0.1 0.2 0.2 0.6 0.2 0.8
Pulse wave reflection index 0.8 1.0 2.4 -0.1 0.4 0.8 1.1 0.5 0.9 0.5 1.3 -1.0 -0.1 -0.4 0.7 1.3 1.4 0.9 0.0 0.8 1.6 1.4 1.2 0.8 1.5 1.4 1.0
Ever highly irritable/argumentative for 2 days 2.1 2.5 6.5 -1.1 -2.0 -1.9 -2.4 -2.2 -1.9 -1.9 -1.3 1.9 -1.2 -1.6 -1.6 -2.2 -2.5 -1.7 -1.4 -1.0 -0.2 -0.6 -0.7 -1.3 0.0 -1.5 -0.8
Loud music exposure frequency 0.7 0.8 3.4 0.3 0.2 1.9 0.4 1.0 0.4 0.8 1.0 -0.7 1.3 0.9 1.7 0.5 0.4 1.0 0.2 0.7 1.0 1.0 0.2 1.1 0.5 0.7 0.7
Qualifications: O levels/GCSEs or equivalent 0.3 0.4 2.5 -0.6 -0.2 0.6 0.2 -0.1 0.3 -0.1 0.1 -0.4 0.1 -0.2 -0.2 0.5 0.1 0.4 0.6 0.3 1.5 1.6 1.3 0.1 0.9 0.6 0.4
Mouth/teeth dental problems: Bleeding gums 2.3 3.0 5.1 -0.5 -1.6 -1.7 -1.9 -2.2 -2.1 -2.1 -1.8 1.7 -0.1 -1.6 -1.6 -2.2 -2.1 -1.9 -1.6 -1.4 -2.2 -0.8 -1.9 -1.0 -1.1 -2.1 -1.8
Blood clot in the leg (DVT) 1.1 1.4 3.8 1.2 1.5 0.8 1.1 0.9 1.5 1.2 -0.3 -0.9 0.0 0.9 0.8 1.4 1.3 1.2 1.3 0.7 1.9 2.0 1.3 0.9 1.6 1.3 1.0
Medication: Paracetamol 2.6 4.2 7.5 1.7 2.3 1.4 1.9 2.6 2.0 2.7 2.7 -1.9 0.7 2.3 2.7 1.8 1.6 2.5 1.1 1.7 1.8 2.4 2.0 2.5 1.2 1.9 2.2
Headache pain in last month 0.4 0.8 2.9 0.4 0.4 0.4 0.3 0.8 0.2 1.0 1.0 -0.5 -0.4 1.1 1.2 0.4 -0.3 1.1 0.7 0.7 0.7 1.6 0.9 1.7 -0.3 0.6 1.5
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 1.3 -0.3 0.9 0.3 0.8 1.1 0.9 0.7 -0.5 -0.5 0.2 1.1 0.0 0.9 1.0 0.1 0.3 1.1 1.0 -1.0 1.1 -0.3 0.5 0.4 0.4
Glaucoma (self-reported) 1.4 1.7 4.4 -0.2 -0.6 -1.2 -1.3 -1.2 -1.1 -1.1 -2.1 1.2 -0.4 -0.6 -1.6 -1.6 -1.3 -1.6 -0.1 -1.0 -1.0 -2.1 -0.9 -1.6 -1.6 -1.8 -1.6
Gout (self-reported) 0.2 0.3 2.0 0.4 -0.1 0.9 -0.2 -0.4 -0.5 0.0 -0.2 -0.2 0.6 0.3 -0.2 -0.6 -0.0 0.2 0.5 0.3 -0.1 1.0 0.6 0.9 -1.4 -0.1 0.7
Hypothyroidism/myxoedema (self-reported) 0.1 0.2 1.6 -0.2 -0.2 0.5 0.0 0.1 -0.3 0.0 0.5 -0.5 -0.2 -0.5 -0.1 0.1 -0.0 0.3 0.3 1.0 -0.0 1.3 0.7 0.7 -0.4 0.1 0.5
Medication: Amlodipine 0.4 0.5 1.8 0.6 -0.5 -0.2 -1.2 -1.3 -0.6 -0.6 0.4 1.0 -0.9 -0.9 -0.0 -0.5 -1.2 -0.4 -0.4 -0.4 -0.1 0.5 -0.9 0.4 0.7 0.0 0.7
Medication: Ventolin 100micrograms inhaler 0.6 0.7 2.2 -0.2 -0.9 -1.5 -0.4 -0.9 -0.6 -1.1 -0.9 0.5 0.3 -0.6 -0.8 -0.6 -0.8 -1.0 -0.9 -0.7 -1.0 -1.4 -1.0 -0.7 -0.6 -0.8 -0.9
Birth weight 0.9 1.9 3.9 1.4 1.5 2.0 1.2 1.4 1.0 1.5 1.0 -1.3 1.8 1.6 1.3 0.8 0.6 1.3 1.2 1.5 1.0 1.7 1.4 2.0 -0.1 1.1 1.7
Chronic bronchitis/emphysema (mother) 1.0 1.1 7.6 -0.3 -1.1 -0.4 -1.0 -1.1 -1.0 -1.2 -0.7 0.9 -1.3 -1.3 -1.2 -0.7 -0.2 -0.6 -2.8 -1.3 -0.7 -0.1 -0.6 -1.2 0.7 -0.7 -1.1
High blood pressure (siblings) 0.2 0.3 1.0 0.5 -0.9 0.4 -1.0 -0.8 -0.8 -0.4 -0.0 0.5 -0.4 -0.9 -0.1 -0.7 -0.9 -0.4 -0.6 -0.5 -0.0 0.8 -0.3 0.4 -0.0 -0.2 0.3
Forced vital capacity (FVC), Best measure 0.2 0.8 3.8 0.9 1.9 0.8 1.2 0.5 0.9 1.1 -0.1 -0.9 1.4 0.9 0.3 0.7 1.1 0.5 1.0 1.3 0.6 -0.2 0.2 0.7 -0.0 0.6 0.5
Body fat percentage 2.8 11.0 27.1 5.2 2.6 3.6 2.5 3.0 2.6 3.3 3.5 -2.8 3.9 2.8 3.2 2.3 2.5 3.7 2.4 4.0 3.0 3.5 3.5 4.2 1.3 3.4 4.2
Leg fat percentage (right) 2.4 8.6 21.6 4.7 2.0 3.6 2.1 2.9 2.0 3.0 3.2 -2.6 3.3 2.6 2.8 1.6 2.1 3.2 2.2 3.8 2.2 2.7 3.1 4.1 0.3 2.9 4.0
Arm fat-free mass (right) 1.6 8.3 19.9 4.5 3.0 4.3 2.5 2.4 2.3 3.3 2.6 -2.3 2.3 2.2 2.7 2.1 2.3 3.3 1.9 3.0 2.8 3.2 2.7 3.6 0.6 2.9 3.6
Exposure to tobacco smoke outside home 2.6 3.5 8.4 2.9 1.7 2.5 1.2 1.5 1.9 1.9 2.6 -1.2 2.3 1.4 2.3 1.5 1.0 2.2 0.0 1.2 2.2 1.9 0.9 1.8 1.8 2.1 2.3
Comparative body size at age 10 1.3 3.6 9.7 1.1 1.6 2.8 1.3 1.2 1.9 1.7 1.4 -1.4 0.2 2.0 1.5 1.3 1.6 1.7 2.8 2.9 3.1 1.4 2.4 0.9 2.3 2.3 2.0
Number of full brothers 3.6 4.6 6.9 1.6 2.1 1.7 2.4 2.2 2.3 2.3 1.8 -2.6 1.8 1.7 2.4 2.5 2.2 2.6 1.3 1.8 2.0 2.5 2.4 2.4 1.0 2.5 2.1
Worry too long after embarrassment 0.4 0.7 2.5 -0.2 -1.4 -1.6 -0.9 -1.0 -0.7 -1.4 -0.8 0.6 -1.4 -1.2 -1.1 -0.7 -0.9 -0.6 -1.0 -0.3 -0.1 0.0 0.4 -0.4 0.2 0.1 0.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 3.0 -0.2 -0.1 0.1 0.5 0.3 0.1 0.3 0.9 -1.0 -0.1 -0.5 0.7 0.5 -0.3 0.7 0.2 0.5 0.2 0.9 1.0 1.6 -1.7 0.4 1.1
Wheeze or whistling in the chest in last year 0.6 1.1 4.6 1.8 0.6 0.8 0.5 0.7 0.6 0.9 1.1 0.3 0.8 0.3 1.9 1.2 0.5 1.0 -1.0 0.0 1.1 1.6 0.1 0.4 2.1 1.0 1.0
Number of children fathered 0.3 0.3 1.5 -0.8 0.3 -0.1 0.5 0.6 0.3 0.5 -0.3 -0.6 -1.0 1.1 -0.1 0.3 0.4 -0.1 0.2 0.6 0.2 -1.2 0.5 -0.1 -0.5 0.2 -0.1
Reason for reducing amount of alcohol drunk: Health precaution 2.6 3.1 6.3 -1.7 -1.9 -2.2 -1.8 -2.5 -1.9 -2.1 -1.5 2.2 -1.1 -2.3 -1.3 -1.3 -1.4 -2.0 -1.6 -1.6 -1.9 -1.2 -1.5 -2.1 0.0 -1.6 -1.9
Age at first live birth 0.3 0.5 1.5 -0.7 0.7 0.3 0.8 0.8 0.8 0.8 -0.4 -0.4 0.4 0.7 -0.1 0.7 1.1 0.3 0.9 0.8 0.7 -0.6 0.6 -0.6 1.2 0.6 -0.3
Pulse wave peak to peak time 3.4 4.0 6.7 -1.4 -1.5 -2.0 -2.2 -2.1 -2.2 -1.9 -2.0 2.2 -1.9 -1.3 -1.6 -1.9 -2.0 -2.2 -1.9 -2.4 -1.9 -1.6 -2.3 -2.6 -0.7 -2.5 -2.6
Health satisfaction 3.5 4.5 9.6 -1.2 -2.6 -1.7 -2.9 -2.9 -2.5 -2.4 -2.2 2.6 -2.3 -3.1 -2.2 -2.6 -2.2 -1.8 -2.6 -2.0 -0.8 -0.5 -1.6 -1.7 0.1 -1.7 -1.4
Shortness of breath walking on level ground 0.2 0.2 0.8 -0.6 -0.1 -0.8 -0.3 -0.3 -0.4 -0.2 -0.9 0.6 0.4 -0.3 -0.4 -0.4 -0.3 -0.3 -0.7 -0.5 -0.2 -0.5 -0.2 -0.3 0.0 -0.4 -0.2
Qualifications: College or University degree 0.3 1.0 5.4 -2.3 -1.4 -0.8 -1.1 -0.9 -1.5 -0.9 -0.7 0.5 -0.3 -1.6 -0.5 -1.0 -0.5 -0.7 -0.8 -0.0 -0.9 -0.5 -0.5 -0.7 -1.3 -1.0 -0.4
Eye problems/disorders: None of the above 1.9 2.2 6.1 0.9 1.5 1.5 1.6 2.0 1.4 2.1 2.4 -1.1 2.5 1.1 2.1 1.7 1.1 1.6 -0.2 1.0 1.1 0.8 0.4 1.5 1.0 1.6 1.3
Mouth/teeth dental problems: Loose teeth 0.4 0.5 3.3 0.3 -0.5 -0.4 -0.2 -1.1 -0.7 -0.7 -0.7 -0.4 -0.2 -1.4 -0.2 -0.3 -0.6 -0.1 0.8 0.2 -0.8 0.6 -0.1 0.9 -1.8 -0.1 0.3
Emphysema/chronic bronchitis 0.3 0.3 0.9 0.1 -0.1 -0.1 0.6 0.8 0.3 0.5 0.4 -0.9 0.3 0.4 0.4 0.3 0.6 0.6 -0.2 0.5 -0.3 -0.2 0.6 0.9 -0.9 0.4 0.8
Medication for pain relief, constipation, heartburn 0.7 1.1 3.5 -1.2 -0.7 -0.7 -0.5 -1.1 -0.6 -1.1 -1.8 0.9 0.5 -0.6 -1.4 -0.5 -0.7 -1.2 0.2 -0.7 -1.2 -1.9 -1.2 -1.6 -0.4 -1.0 -1.6
Neck or shoulder pain in last month 1.3 1.8 5.9 -1.9 -0.7 -1.0 -1.2 -1.0 -1.1 -0.9 -0.8 1.5 -0.4 -1.0 -0.4 -0.8 -1.1 -1.3 -1.2 -1.7 -2.2 -1.4 -2.0 -1.7 -0.3 -1.5 -2.4
Medication: Blood pressure 1.7 3.0 6.6 -0.6 -2.2 -1.5 -2.4 -2.5 -2.3 -1.9 -0.6 1.7 -1.4 -2.6 -1.0 -2.3 -2.5 -1.4 -1.3 -1.8 -1.8 -0.1 -2.0 -0.7 -0.6 -1.5 -1.3
Angina (self-reported) 0.3 0.4 2.0 -0.9 -0.5 -1.1 -0.4 -0.7 -0.3 -0.5 0.3 0.4 -1.2 -1.4 0.4 0.2 -0.6 -0.1 -0.9 -1.0 -0.8 0.4 -0.6 0.1 0.4 -0.0 -0.4
Migraine (self-reported) 0.3 0.4 1.7 -0.0 0.5 0.2 0.7 0.6 0.2 0.9 1.2 -0.3 0.7 0.7 1.3 0.6 1.1 0.4 0.5 0.5 0.0 -0.3 0.0 -0.3 0.1 -0.0 -0.6
Medication: Ibuprofen 1.0 1.2 3.7 0.3 -0.9 -0.2 -1.5 -0.9 -1.2 -0.9 -1.0 1.5 -0.8 -0.5 -0.9 -1.6 -0.9 -1.1 -1.9 -1.6 -0.2 -0.5 -1.5 -1.1 -0.0 -1.3 -0.9
Medication: Allopurinol 0.4 0.5 2.3 0.6 0.1 1.1 0.1 -0.1 -0.2 0.3 0.5 -0.7 0.6 0.2 0.4 -0.0 0.2 0.7 0.4 0.3 0.2 1.5 0.6 1.5 -0.9 0.4 1.3
Medication: Omeprazole 1.7 2.0 6.7 -0.5 -2.0 -1.2 -1.5 -1.9 -1.6 -1.8 -2.0 1.1 -2.6 -2.5 -1.7 -1.6 -1.2 -1.2 -1.7 -0.6 0.0 0.1 -0.2 -0.7 -0.5 -0.8 -0.2
Medication: Seretide 50 evohaler 0.8 0.9 2.1 1.2 1.1 1.4 1.2 0.9 1.2 0.9 1.1 -0.8 1.2 0.9 0.9 1.1 1.0 1.2 -0.1 -0.0 0.7 1.3 0.4 0.9 0.0 0.8 0.6
Mean time to correctly identify matches 0.3 0.7 2.0 -0.1 0.5 0.2 0.8 0.4 0.8 0.6 0.1 -1.0 0.5 0.7 0.5 0.5 0.7 0.7 1.4 1.2 0.3 0.1 1.3 1.4 -0.4 1.0 1.2
Heart disease (mother) 0.9 1.1 2.8 0.4 1.4 0.5 1.1 1.1 1.2 1.2 1.0 -0.9 1.1 0.2 1.7 1.4 1.0 1.1 0.6 1.2 0.8 0.5 0.6 1.2 1.2 1.3 1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.4 2.2 -0.6 -0.3 -1.2 -0.2 -0.2 -0.4 -0.8 0.2 0.4 0.2 -0.2 0.5 0.1 0.0 -0.6 -1.3 -0.5 -0.9 -1.5 -0.5 -0.7 -0.5 -0.4 -0.9
Whole body fat mass 3.6 15.2 35.0 5.9 3.4 4.7 3.1 3.6 3.1 4.2 3.9 -3.3 4.2 3.4 3.7 2.8 3.0 4.4 2.9 4.5 3.7 4.3 4.0 5.0 1.4 4.0 4.9
Leg fat mass (right) 3.1 12.2 27.7 5.3 2.9 4.5 2.7 3.2 2.6 3.7 3.5 -3.0 3.9 3.0 3.4 2.2 2.6 3.9 2.8 4.2 3.1 3.5 3.5 4.6 0.7 3.5 4.6
Arm predicted mass (right) 1.7 8.7 21.5 4.6 3.1 4.3 2.5 2.6 2.4 3.4 2.9 -2.2 2.2 2.4 2.9 2.2 2.3 3.3 2.0 3.0 3.0 3.2 2.8 3.5 1.0 3.0 3.7
Pulse rate, automated reading 2.4 7.8 21.3 -0.3 -2.6 -3.0 -3.0 -2.8 -2.3 -3.4 -4.6 2.5 -3.2 -1.7 -4.5 -3.9 -2.5 -3.2 -1.5 -0.8 -1.6 -4.4 -1.2 -3.0 -1.1 -2.3 -1.8
Alcohol intake frequency. 0.3 0.7 5.1 0.2 -0.7 -0.6 -0.6 -1.0 -0.9 -0.7 -0.7 0.4 -0.5 -0.5 -0.9 -0.8 -1.0 -0.9 -0.8 0.0 -0.1 -2.3 -0.8 -0.8 -1.0 -0.6 -0.4
Comparative height size at age 10 1.2 6.8 15.8 2.5 2.8 3.3 2.7 2.1 2.4 2.7 3.0 -2.5 2.8 0.8 3.8 3.3 2.8 3.3 0.7 1.8 1.5 4.0 1.7 3.1 0.6 2.8 2.3
Number of full sisters 1.1 1.4 4.8 -0.1 1.5 0.7 1.7 1.7 1.7 1.1 1.8 -1.1 0.6 1.7 1.6 2.2 1.7 0.8 0.6 0.1 0.6 -0.5 0.4 -0.2 0.4 0.9 -0.1
Suffer from ‘nerves’ 4.0 6.2 13.0 2.1 2.9 1.9 2.6 2.4 2.9 2.8 2.4 -2.6 1.6 1.3 2.6 3.2 2.0 3.1 1.3 1.4 2.5 3.6 2.1 3.2 1.7 3.0 2.8
Overall health rating 2.4 5.1 9.0 -1.2 -2.5 -1.9 -2.8 -2.3 -2.8 -2.3 -2.2 2.5 -2.2 -2.6 -2.0 -2.5 -3.0 -2.1 -2.3 -2.4 -2.5 -1.0 -2.9 -1.1 -1.9 -2.3 -1.5
Chest pain or discomfort 1.7 2.4 7.7 -1.5 -2.1 -1.7 -1.7 -1.6 -1.8 -1.6 -0.8 1.1 -1.9 -2.1 -1.1 -1.4 -2.0 -1.1 -2.8 -2.0 -1.7 0.5 -1.0 -0.1 -1.1 -1.1 -0.7
Had major operations 0.3 0.3 1.7 -0.1 0.5 0.2 0.3 -0.1 0.2 -0.1 0.8 -0.4 0.5 -0.1 1.0 0.5 0.6 0.1 -0.4 0.7 0.6 -1.3 -0.2 0.6 -0.1 0.5 0.9
Age at last live birth 0.3 0.4 1.6 -1.3 0.4 -0.0 0.7 0.6 0.7 0.6 -0.1 -0.3 -0.1 0.6 0.0 0.9 1.0 0.2 0.1 -0.1 0.4 -0.8 0.3 -0.9 1.1 0.4 -0.4
Family relationship satisfaction 3.2 4.0 8.5 -1.2 -2.9 -1.1 -2.5 -2.3 -2.8 -2.2 -1.7 2.0 -1.2 -2.7 -2.0 -2.3 -2.2 -1.6 -2.4 -2.2 -1.6 1.2 -1.6 -0.8 -1.6 -2.1 -1.5
Leg pain on walking 0.5 0.6 2.3 1.3 1.1 1.2 0.4 0.6 0.9 0.8 0.9 -0.3 1.2 1.5 0.5 0.3 0.1 0.4 0.6 0.6 0.5 -0.0 0.4 0.8 0.4 0.6 0.9
Qualifications: NVQ or HND or HNC or equivalent 1.7 2.0 4.1 -0.9 -2.0 -1.6 -1.9 -1.6 -1.6 -1.6 -0.8 1.9 -1.2 -1.8 -1.1 -1.3 -1.8 -1.5 -1.6 -1.6 -0.9 0.2 -0.8 -1.5 0.4 -1.2 -1.5
Commuting to job workplace: Car/motor vehicle 0.2 0.3 2.6 -0.0 -0.0 -0.0 -0.1 0.1 0.2 0.2 -0.1 0.1 0.2 0.3 0.4 -0.1 -0.1 0.4 1.6 0.4 0.1 1.1 0.8 0.3 1.0 0.4 0.4
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 3.1 0.0 0.7 0.2 0.8 0.3 0.8 0.5 0.8 -0.2 1.6 0.6 0.5 0.9 0.6 0.4 1.8 0.6 0.6 0.8 0.6 -0.1 1.5 0.5 -0.0
Medication: Aspirin 0.8 1.1 3.1 0.8 0.7 0.9 0.9 0.6 1.1 0.8 1.2 -1.1 -0.2 -0.3 0.7 1.1 1.1 1.2 1.0 0.8 1.1 1.8 1.6 0.8 1.3 1.4 1.1
Supplements: Vitamin C 2.8 3.3 5.1 0.8 2.1 0.8 2.0 1.3 2.0 1.9 1.2 -1.9 1.9 1.4 1.8 2.0 2.2 2.0 1.8 1.9 2.2 1.2 2.3 1.5 2.1 2.2 1.8
Knee pain experienced in last month 1.8 2.7 8.8 3.0 1.5 1.8 1.2 1.8 1.4 1.8 1.3 -1.7 1.3 2.7 0.8 0.6 1.5 1.6 1.8 1.8 1.6 0.7 1.6 2.2 -0.2 1.3 1.9
Hypertension (Self-reported) 0.8 2.2 5.5 0.4 -2.1 -0.5 -2.3 -2.0 -1.7 -1.5 0.2 1.8 -2.0 -2.0 0.1 -1.7 -2.3 -0.9 -1.6 -1.8 -1.2 0.5 -2.2 -0.4 -0.1 -0.7 -0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.4 1.7 -0.2 -1.0 -1.2 -0.5 -0.9 -0.6 -0.8 -0.5 0.1 -0.3 -1.3 -0.8 -0.4 -0.3 -0.2 -1.3 -0.3 0.4 0.6 0.5 -0.0 0.4 -0.0 0.1
Illnesses of father: Heart disease 0.5 0.7 2.9 0.2 -1.2 -0.4 -0.8 -1.0 -1.0 -1.2 -1.0 0.1 -0.4 -0.7 -1.1 -1.7 -0.8 -1.2 -0.1 0.0 -0.7 -0.5 0.4 -0.7 -1.1 -1.0 -0.7
Illnesses of siblings: Diabetes 0.3 0.3 2.7 -0.2 0.4 -0.2 0.1 0.2 0.6 0.2 -0.0 0.4 -0.3 -0.0 0.3 0.8 0.2 0.1 -0.6 -0.7 0.8 1.0 0.2 -0.6 1.6 0.5 -0.1
Smoking status: Previous 4.8 7.2 12.5 1.5 2.6 2.5 2.8 2.9 2.4 2.8 3.5 -3.3 1.4 2.6 3.4 2.6 2.7 3.3 2.8 2.6 1.3 3.1 2.5 3.5 0.3 2.7 2.5
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.4 1.5 1.1 1.2 0.7 0.8 0.1 0.4 0.9 -0.0 -0.4 0.6 0.4 0.9 0.7 0.7 0.5 -0.6 0.7 0.9 -0.3 0.2 0.3 0.7 0.7 0.8
Whole body fat-free mass 1.6 9.1 19.8 4.5 3.4 4.3 2.7 2.6 2.5 3.5 3.0 -2.3 2.6 2.5 3.2 2.5 2.5 3.4 2.0 2.9 2.9 3.2 2.5 3.7 0.9 3.0 3.8
Leg fat-free mass (right) 2.0 10.8 22.2 4.7 3.7 4.2 3.0 2.7 2.9 3.7 2.9 -2.6 2.5 2.8 3.2 2.8 2.7 3.7 2.6 3.3 3.6 3.5 3.0 3.9 1.4 3.4 4.2
Arm fat percentage (left) 2.4 9.6 25.2 5.0 2.5 3.6 2.3 2.7 2.4 3.1 2.9 -2.5 3.3 2.8 2.9 1.9 2.3 3.5 2.6 3.9 3.1 3.1 3.3 4.0 1.1 3.2 4.2
Average weekly red wine intake 0.7 1.0 3.0 -1.2 -1.3 0.3 -1.2 -0.9 -1.0 -1.3 -0.5 1.4 -1.6 -0.3 -1.0 -1.0 -0.8 -1.2 -0.6 0.0 -0.5 -1.3 -0.9 -1.7 0.4 -0.7 -0.9
Handedness (chirality/laterality): Left-handed 0.5 0.5 1.9 -0.5 -1.0 0.3 -0.7 -0.7 -0.9 -0.7 -0.0 0.6 1.0 -0.8 0.2 -0.9 -0.7 -0.4 -0.2 -0.6 -0.6 -0.8 -1.4 -0.1 -1.4 -0.6 -0.3
Mood swings 0.7 1.2 3.2 0.6 1.3 0.8 0.8 1.0 1.0 1.6 0.9 -1.0 1.1 1.4 1.4 0.9 0.3 1.2 0.8 1.2 1.2 1.0 0.7 1.6 0.3 1.2 1.8
Loneliness, isolation 0.5 0.6 3.5 0.6 -0.9 -0.0 -0.8 -0.8 -0.9 -0.7 -1.0 0.4 -0.6 -0.1 -0.6 -1.2 -1.0 -0.7 0.1 -0.3 -0.6 -0.5 -1.0 -0.1 -1.9 -1.0 -0.7
Long-standing illness, disability or infirmity 2.2 3.4 6.0 -0.8 -2.4 -1.5 -2.4 -2.2 -2.4 -2.0 -2.1 2.1 -2.1 -2.5 -1.8 -2.2 -2.1 -1.6 -1.8 -1.7 -1.9 -0.0 -1.8 -0.7 -1.2 -1.7 -1.1
Ever had bowel cancer screening 3.2 3.7 7.7 0.9 2.2 1.1 2.5 1.3 2.3 1.8 2.0 -2.3 1.6 1.3 1.8 2.8 2.3 1.8 1.3 1.7 1.7 2.1 2.0 1.7 2.3 2.4 1.6
Diabetes diagnosed by doctor 0.3 0.5 3.1 1.8 0.9 0.4 0.2 0.5 0.5 1.0 0.1 0.2 0.8 1.3 0.3 -0.1 -0.2 0.7 0.9 -0.5 -0.3 0.7 -0.2 0.8 -0.2 0.2 0.3
Ever had stillbirth, spontaneous miscarriage or termination 2.1 2.2 5.0 -1.7 -1.6 -0.8 -1.1 -1.0 -1.4 -1.6 -1.6 1.2 -2.1 -0.9 -2.0 -1.0 -0.6 -1.5 -1.7 -1.7 -1.0 -1.3 -1.2 -2.2 -0.9 -1.7 -2.2
Friendships satisfaction 0.5 0.7 3.1 -1.0 -1.3 -0.1 -0.7 -0.9 -1.3 -1.0 -0.4 0.5 -0.6 -1.6 -0.4 -0.6 -0.2 -0.2 -0.7 -0.2 -0.4 1.8 -0.6 -0.0 -0.5 -0.5 -0.5
Qualifications: nursing, teaching 0.2 0.3 1.4 -0.9 -1.0 -0.1 -0.2 -0.6 -0.5 -0.8 -0.7 -0.2 -1.2 -0.7 -0.7 -0.2 0.3 -0.2 -1.1 -0.2 0.2 0.4 0.5 -0.2 -0.3 -0.0 -0.2
Commuting to job workplace: Walk 0.2 0.2 0.9 -0.1 -0.1 -0.5 -0.3 0.1 -0.2 -0.2 0.3 0.6 0.4 0.2 -0.0 -0.3 -1.0 -0.5 -1.0 -0.5 -0.4 -0.7 -0.7 -0.7 -0.1 -0.4 -0.7
Eye problems/disorders: Cataract 1.3 1.5 4.5 -0.6 -1.0 -1.1 -1.4 -2.0 -1.1 -1.7 -1.1 1.3 -2.1 -1.2 -1.1 -1.2 -1.1 -1.3 0.6 -1.2 -1.3 0.1 -1.1 -1.0 -0.1 -1.2 -1.1
Mouth/teeth dental problems: Mouth ulcers 1.3 2.1 4.4 -2.1 -1.6 -0.9 -1.4 -0.8 -1.3 -1.3 -0.9 1.6 -1.7 -0.7 -1.3 -1.0 -1.2 -1.5 -0.9 -1.5 -1.7 -2.1 -2.0 -1.7 -0.7 -1.6 -1.9
Medication for cholesterol 0.1 0.2 0.9 -0.6 -0.2 -0.4 -0.1 0.0 -0.7 0.1 -0.8 0.0 1.0 0.1 -0.6 -0.6 -0.3 -0.1 -0.4 -0.1 -0.4 -0.4 -0.3 0.2 -0.6 -0.8 -0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.1 0.4 -0.6 0.0 -0.2 -0.2 -0.3 -0.5 0.3 -0.5 0.0 -0.5 -0.1 -0.2 -0.6 -0.3 -0.2 0.4 -0.1 -0.4 -0.3 -0.4 0.1 -0.6 -0.4 -0.1
Back pain experienced in last month 0.1 0.1 0.4 0.6 0.1 0.2 0.2 -0.1 -0.1 0.4 0.3 -0.2 -0.5 0.4 0.3 0.1 -0.0 -0.1 0.1 0.1 -0.4 0.4 -0.2 0.4 -0.5 -0.0 0.2
Mineral and other dietary supplements 2.3 3.1 7.6 -0.4 -1.9 -2.8 -2.5 -1.9 -1.9 -2.0 -1.5 2.1 -1.3 -1.6 -1.8 -2.1 -2.7 -1.7 -1.8 -1.6 -1.2 -1.1 -1.4 -1.4 -0.4 -1.6 -1.1
Breast cancer (self-reported) 2.1 2.5 3.9 -0.7 -0.6 -1.2 -1.6 -1.8 -1.6 -1.3 -1.9 1.9 -1.7 -1.4 -1.9 -1.8 -1.2 -1.7 -0.7 -1.6 -1.9 -1.7 -1.9 -1.7 -1.0 -2.0 -1.9
Asthma (self-reported) 0.9 1.7 4.3 1.4 0.7 1.3 1.1 1.6 0.8 1.5 1.9 -1.0 1.8 0.8 2.1 1.3 1.0 1.7 0.2 0.8 1.1 1.8 1.0 1.7 0.1 1.1 1.6
Osteoporosis (self-reported) 1.2 1.5 4.6 0.5 -1.1 -0.6 -1.3 -0.6 -1.2 -1.2 -0.7 1.4 -1.4 -0.8 -0.6 -1.1 -0.6 -1.5 -1.9 -0.7 -1.8 -2.1 -1.6 -1.6 0.3 -1.1 -1.3
Osteoarthritis (self-reported) 0.3 0.5 2.0 1.0 0.7 1.2 0.5 0.5 0.5 0.7 -0.2 -0.8 0.2 0.9 0.3 0.1 0.5 0.5 0.6 0.5 -0.1 1.4 0.3 1.2 -0.1 0.3 0.5
Medication: Aspirin 0.8 1.1 2.5 0.7 0.9 0.8 0.9 0.5 1.1 0.9 1.1 -1.1 0.2 -0.4 0.9 1.2 1.1 1.2 1.0 0.8 1.1 1.6 1.6 0.8 1.5 1.4 1.0
Medication: Gliclazide 0.9 1.0 2.8 1.1 1.7 -0.1 1.0 0.9 1.2 1.4 1.2 -0.6 1.2 1.1 1.2 1.2 0.8 1.1 0.9 0.3 -0.3 0.8 0.1 1.0 0.9 1.1 0.5
Illnesses of father: None of the above (group 1) 0.9 1.1 4.4 1.4 1.4 0.2 0.7 0.7 1.4 1.1 0.7 -0.3 0.9 0.7 0.8 1.3 1.1 1.1 0.9 0.7 1.3 1.0 1.2 0.5 2.1 1.4 0.9
Smoking status: Current 0.4 0.6 2.6 1.3 -0.8 0.2 -0.7 -0.3 -0.3 -0.3 1.6 0.7 1.1 -0.1 1.0 -0.1 -0.7 -0.2 -1.5 -1.4 -0.3 0.7 -0.9 -0.0 0.9 -0.0 0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.1 2.3 6.9 1.6 2.4 0.8 1.3 1.6 1.6 1.9 0.5 -1.1 1.7 2.0 0.7 1.0 0.9 1.0 2.1 2.6 1.4 -1.2 1.6 0.8 0.6 1.3 1.6
Whole body water mass 1.6 9.4 19.8 4.5 3.5 4.4 2.8 2.6 2.6 3.6 3.1 -2.3 2.6 2.5 3.2 2.6 2.5 3.5 2.0 2.9 2.9 3.2 2.5 3.7 0.9 3.1 3.8
Leg predicted mass (right) 2.1 11.5 22.8 4.8 3.8 4.3 3.2 2.8 3.1 3.8 3.0 -2.6 2.6 2.9 3.3 3.0 2.8 3.8 2.7 3.4 3.8 3.6 3.1 4.0 1.4 3.6 4.3
Arm fat mass (left) 3.3 13.5 32.1 5.7 3.3 4.6 2.9 3.2 2.9 3.9 3.5 -3.0 3.7 3.3 3.4 2.4 2.8 4.1 2.9 4.2 3.5 4.0 3.6 4.7 1.3 3.7 4.8
Number of self-reported non-cancer illnesses 0.2 0.3 1.9 0.2 -0.5 -0.7 -0.4 -0.3 -0.7 -0.0 0.4 0.1 0.4 -0.4 0.3 -0.3 -0.6 -0.2 -0.6 -0.4 -1.4 0.8 -0.4 0.9 -0.7 -0.3 0.1
Average weekly champagne plus white wine intake 1.2 1.6 6.9 -0.8 -1.2 -0.6 -1.5 -2.1 -1.4 -1.8 -1.6 1.1 -2.6 -2.2 -1.3 -1.4 -0.7 -1.0 -1.3 -0.1 -0.3 -0.6 -1.1 -0.6 -0.0 -0.6 -0.2
Miserableness 0.1 0.2 0.9 0.6 -0.1 -0.2 -0.8 -0.9 -0.3 -0.2 0.2 0.5 -0.6 -0.3 0.1 -0.6 -1.0 -0.1 -0.2 -0.0 0.7 0.4 0.1 0.6 0.2 0.3 0.7
Guilty feelings 2.5 3.7 6.6 0.8 2.4 1.9 2.4 2.1 2.1 2.4 2.1 -2.0 2.4 1.2 2.5 2.6 2.4 2.4 0.8 0.6 0.7 2.1 0.9 2.3 0.1 2.0 1.7
Wears glasses or contact lenses 1.9 2.2 5.7 -1.9 -1.7 -1.6 -1.6 -1.9 -1.7 -2.0 -0.4 1.5 -1.1 -2.4 -0.4 -0.7 -1.3 -1.5 -1.7 -1.3 -1.2 -1.6 -1.9 -1.5 0.0 -0.9 -1.3
Ever taken oral contraceptive pill 0.5 0.5 1.6 0.4 0.7 0.9 0.5 0.6 0.3 0.5 1.3 -0.3 1.2 0.8 1.2 0.7 0.1 0.6 -0.3 0.6 0.2 1.2 0.1 1.1 0.2 0.3 0.8
Hearing aid user 0.9 1.0 3.7 -0.4 -1.0 -0.7 -1.1 -1.8 -1.1 -1.1 -1.9 0.8 -1.2 -1.9 -1.6 -1.3 -1.1 -0.6 0.4 0.4 -0.4 0.5 -0.3 -0.1 -0.3 -0.5 -0.0
Mother’s age at death 0.2 0.3 1.9 0.4 -0.2 0.3 0.3 -0.0 0.3 -0.2 -0.3 -0.6 0.4 -0.1 0.2 0.3 0.5 0.3 0.3 0.7 0.9 0.8 0.9 -0.0 1.4 0.6 0.4
Financial situation satisfaction 0.2 0.2 1.7 0.6 -0.2 1.1 -0.3 0.0 -0.4 0.2 0.3 0.2 0.1 -0.3 0.2 -0.4 0.2 0.3 0.1 0.2 0.6 1.3 0.2 0.2 0.2 -0.1 0.3
Tinnitus: Yes, now most or all of the time 0.3 0.3 2.0 -0.0 0.2 0.9 0.4 -0.1 -0.0 -0.1 0.0 -0.8 0.1 -0.1 0.6 0.1 0.1 0.0 0.6 1.0 -0.2 -0.6 -0.9 0.6 -1.4 -0.1 0.2
Commuting to job workplace: Public transport 2.3 2.7 5.0 -0.5 -1.5 -1.7 -2.1 -1.4 -1.9 -1.5 -1.2 1.5 -1.4 -1.6 -2.2 -2.1 -1.9 -1.7 -2.2 -1.8 -1.6 -0.9 -1.2 -1.1 -1.7 -2.1 -1.4
Eye problems/disorders: Glaucoma 0.8 0.9 2.5 0.1 -0.6 -0.6 -1.1 -1.0 -1.1 -0.7 -1.4 0.8 -0.3 -0.2 -1.2 -1.5 -1.1 -1.0 0.4 -0.7 -0.9 -1.0 -0.4 -0.7 -1.6 -1.4 -1.0
Medication: Blood pressure 0.5 0.9 4.6 1.5 0.4 1.3 0.3 0.3 0.8 0.6 2.1 -0.3 -0.2 0.2 2.0 1.0 0.4 0.9 -0.3 -0.3 0.4 1.4 -0.1 0.7 0.5 1.1 0.8
Pain type(s) experienced in last month: Hip pain 0.2 0.3 1.4 0.8 0.2 0.1 -0.0 -1.0 -0.0 -0.3 -0.4 0.0 -0.8 -0.3 -0.3 -0.3 -0.3 -0.1 0.2 -0.1 0.4 0.7 0.4 0.9 -0.4 0.1 1.2
Supplements: Fish oil (including cod liver oil) 4.5 5.9 10.9 0.4 2.5 3.0 3.2 2.4 2.7 2.7 2.4 -3.1 2.4 1.9 2.5 3.1 3.3 2.6 2.9 1.9 1.7 2.1 2.2 2.2 0.6 2.5 1.8
High cholesterol (Self-reported) 0.4 0.8 3.1 1.3 0.5 0.2 0.3 -0.2 0.6 0.2 1.8 -0.1 0.5 -0.4 1.0 1.0 0.4 0.8 -0.1 0.1 0.5 1.2 0.1 1.1 1.7 1.3 1.2
Medication: Bendroflumethiazide 0.3 0.4 2.0 0.2 -0.6 1.1 -0.9 -0.4 -0.2 -0.2 1.0 1.3 -0.7 -0.5 0.4 -0.2 -0.7 -0.2 -0.4 -0.9 0.2 0.4 -1.4 -0.7 0.5 -0.0 -0.1
Medication: Paracetamol 0.3 0.4 2.1 0.5 0.7 0.1 0.3 0.9 0.3 0.9 1.2 -0.1 -0.7 0.8 1.5 0.3 0.0 0.8 -0.5 -0.3 0.1 1.1 -0.2 0.8 0.6 0.1 0.4
Medication: Lisinopril 0.7 0.9 3.8 0.5 -1.3 -0.8 -1.2 -1.3 -1.2 -1.4 -0.3 1.0 0.1 -1.9 -0.5 -0.9 -0.9 -0.6 -1.4 -0.8 -0.8 0.0 -0.9 -0.8 -0.2 -0.6 -0.5
Medication: Atorvastatin 1.6 2.0 7.2 1.2 2.0 1.4 1.5 0.8 1.2 1.5 2.0 -1.4 0.4 1.2 1.7 1.4 0.8 1.2 1.2 1.8 0.3 1.0 0.3 2.7 -0.2 1.5 2.1
Illnesses of father: High blood pressure 0.5 0.6 2.5 -1.4 -0.4 0.9 -0.4 -0.2 -0.7 0.0 0.4 0.5 -0.4 -0.2 1.0 -0.0 -0.8 -0.1 -0.7 -1.4 -1.3 0.7 -1.6 0.1 -1.1 -0.7 -0.8
Alcohol drinker status: Never 0.4 0.5 1.8 -0.9 0.2 -1.0 0.6 -0.0 0.8 -0.0 0.9 -0.7 -0.7 0.5 0.7 0.9 0.5 -0.0 1.4 0.5 0.2 -0.8 0.6 -0.2 1.2 0.8 -0.2
Ever smoked 2.8 5.0 13.0 1.6 1.8 2.4 2.0 2.0 1.9 2.2 3.6 -2.2 2.0 1.8 3.4 2.4 2.4 2.6 1.6 1.3 1.2 3.2 1.4 2.6 1.3 2.3 2.0
Basal metabolic rate 2.2 11.9 25.6 5.1 3.7 4.7 3.1 3.0 2.9 4.0 3.4 -2.7 3.1 2.9 3.6 2.8 2.8 3.9 2.4 3.4 3.3 3.6 3.0 4.2 1.1 3.5 4.3
Leg fat percentage (left) 2.7 9.7 21.7 4.7 2.3 3.7 2.3 3.0 2.4 3.2 3.3 -2.8 3.2 2.9 2.9 1.9 2.3 3.4 2.4 4.1 2.8 2.8 3.5 4.1 0.8 3.3 4.3
Arm fat-free mass (left) 1.9 9.9 21.8 4.7 3.4 4.7 2.8 2.8 2.6 3.8 3.3 -2.3 2.9 2.8 3.4 2.5 2.5 3.6 2.0 2.7 2.6 3.4 2.4 3.9 0.6 3.0 3.8
Number of operations (self-reported) 2.4 3.6 8.3 2.5 1.8 2.4 1.9 1.4 1.4 1.8 2.2 -2.2 2.2 1.4 1.9 1.3 1.9 1.9 0.9 2.1 1.8 1.8 1.3 2.9 -0.3 1.8 2.6
Average weekly beer plus cider intake 0.5 0.7 2.1 -0.3 0.8 1.0 0.9 1.5 0.7 1.2 1.1 -0.9 1.1 1.3 0.8 0.8 0.7 1.0 0.6 0.2 0.3 1.2 0.5 1.0 0.1 0.4 0.2
Irritability 2.0 3.3 8.4 0.7 2.0 0.5 1.4 1.4 1.6 2.2 1.9 -1.7 1.6 1.8 1.8 1.4 0.8 1.8 2.0 2.6 1.6 1.5 2.5 2.4 1.2 2.0 2.9
Risk taking 0.6 0.9 2.9 0.3 0.8 0.6 0.7 1.7 0.4 1.5 0.8 -1.1 1.3 1.3 0.6 0.3 0.3 1.2 0.1 0.7 -0.6 0.9 0.7 1.6 -1.5 0.4 0.6
Ever had prostate specific antigen (PSA) test 0.6 0.7 1.9 0.4 0.4 -0.0 0.8 0.8 0.8 0.6 0.7 -1.2 0.8 1.2 0.9 0.4 0.4 0.7 1.4 1.2 0.2 -0.2 1.1 1.0 -0.2 0.9 1.1
Fractured/broken bones in last 5 years 0.9 1.1 5.6 1.9 -0.4 1.0 0.5 0.7 0.2 0.1 1.3 -0.5 -0.1 -0.6 1.6 0.6 1.0 1.2 -0.4 0.7 1.6 2.4 0.4 0.8 1.7 0.9 0.8
Age started oral contraceptive pill 0.3 0.3 1.6 0.2 0.4 0.2 0.6 0.6 0.5 0.4 0.8 -0.5 0.8 -0.2 0.7 1.0 0.6 0.5 0.3 0.6 -0.1 1.2 0.0 0.5 0.8 0.5 0.1
Diastolic blood pressure, automated reading 1.0 3.2 11.7 0.7 -1.6 -1.6 -1.7 -2.1 -1.5 -2.4 -2.5 1.3 -1.8 -1.8 -3.0 -2.1 -1.4 -2.1 -1.6 -0.0 -0.8 -3.4 -0.6 -1.3 -1.8 -1.1 -0.4
Ever depressed for a whole week 1.1 1.4 4.4 -0.8 -1.0 -1.1 -1.6 -1.5 -1.5 -1.0 -1.0 0.8 -2.1 -0.9 -1.1 -1.8 -1.8 -1.1 -0.4 0.2 -0.3 -1.1 -0.7 -0.3 -1.4 -1.4 -0.2
Unable to work because of sickness or disability 0.2 0.2 0.6 -0.0 -0.2 0.5 0.3 0.3 0.3 -0.2 0.2 -0.3 -0.1 -0.6 0.6 0.6 0.5 0.7 -0.6 -0.2 -0.2 0.8 -0.1 0.7 0.0 0.6 0.4
Commuting to job workplace: Cycle 2.5 3.1 11.7 1.9 1.5 1.9 1.6 1.7 1.5 2.0 1.3 -1.9 1.1 1.5 1.8 1.2 1.6 2.3 1.4 1.0 1.6 3.4 2.0 2.1 0.5 1.6 1.7
Myopia 2.1 3.0 7.6 -1.9 -1.0 -1.8 -2.4 -2.1 -1.9 -1.5 -1.1 2.8 -1.2 -1.7 -0.8 -1.2 -1.8 -1.9 -2.0 -2.1 -1.3 -0.7 -2.4 -2.2 1.1 -1.6 -1.6
Vascular/heart problems diagnosed by doctor 0.4 1.0 2.3 -1.0 1.4 0.1 1.5 1.4 1.1 0.9 -0.6 -0.8 1.5 1.4 -0.3 1.1 1.5 0.2 1.2 1.2 0.9 -1.0 1.2 -0.4 0.4 0.2 0.0
Cholesterol lowering medication 0.2 0.3 1.2 0.5 -0.1 0.1 -0.1 -0.4 0.2 -0.4 1.1 0.2 -0.3 -1.1 0.6 0.8 0.1 0.0 -0.8 -0.1 0.0 0.6 -0.3 0.4 0.8 0.6 0.5
Medication: Omeprazole (e.g. Zanprol) 0.8 0.9 2.8 0.3 -1.4 -0.7 -0.9 -1.4 -1.0 -1.1 -1.6 0.5 -1.7 -1.7 -1.2 -1.1 -0.9 -0.5 -1.0 0.1 0.8 0.8 0.6 0.1 0.0 -0.0 0.7
Pain experienced in last month 0.1 0.2 1.0 -0.6 0.0 0.2 0.1 -0.4 0.1 -0.6 -0.7 0.0 0.0 -0.6 -0.8 0.0 0.4 -0.4 0.3 0.1 -0.2 -1.0 -0.5 -0.7 0.3 -0.1 -0.4
Supplements: Calcium 1.0 1.1 4.8 0.9 0.7 1.1 1.0 0.2 0.7 0.3 1.4 -0.0 1.0 -0.7 2.1 1.5 1.4 0.8 -0.7 0.4 1.3 1.0 -0.2 0.1 2.2 1.0 0.3
Basal cell carcinoma (self-reported) 0.7 0.9 2.5 -0.3 -1.0 -0.6 -1.3 -0.8 -1.2 -0.5 -1.4 0.8 -1.2 -0.9 -0.9 -1.6 -1.3 -0.7 -0.0 -0.3 -1.3 0.3 -0.2 -0.1 -1.3 -1.0 -0.2
Heart attack/myocardial infarction (self-reported) 0.3 0.4 1.1 0.6 1.1 -0.1 0.8 0.7 0.7 0.8 0.1 -1.0 0.5 0.9 0.1 0.7 0.7 0.5 0.6 0.0 0.2 0.5 0.9 0.6 -0.4 0.3 -0.0
Deep venous thrombosis (DVT) (self-reported) 1.2 1.5 4.0 1.3 1.5 1.0 1.2 1.1 1.6 1.3 -0.2 -1.0 0.1 1.2 1.0 1.4 1.4 1.3 1.2 0.5 1.8 2.0 1.2 0.9 1.4 1.3 1.0
Heart disease (siblings) 0.2 0.2 1.2 0.3 -0.2 0.1 0.2 -0.0 0.0 -0.4 0.4 0.2 -0.6 -1.1 -0.0 0.4 0.4 0.2 -0.8 -0.7 0.5 1.0 0.3 -0.2 0.8 0.1 -0.2
Alcohol drinker status: Previous 0.8 0.9 4.3 -0.8 -1.4 0.1 -0.9 -0.6 -1.1 -0.8 0.3 0.6 -0.6 -1.6 0.1 -0.6 -1.2 -0.5 -2.1 -0.8 -0.6 -0.9 -1.3 -0.7 -0.6 -0.6 -0.8
Pack years of smoking 0.7 1.0 2.3 0.6 -1.3 -1.4 -1.2 -1.3 -1.1 -1.0 -0.4 1.3 1.0 -1.4 -0.5 -0.8 -1.5 -0.8 -1.0 -1.4 -0.5 -0.3 -0.7 -0.7 0.4 -1.0 -0.7
Impedance of whole body 0.3 1.4 4.6 -1.6 -1.1 -2.1 -0.6 -0.8 -0.9 -1.3 -0.9 0.4 0.1 -1.6 -0.7 -0.2 -0.5 -0.9 -1.9 -1.6 -1.8 0.1 -1.2 -1.1 -0.4 -1.1 -2.1
Leg fat mass (left) 3.5 13.8 29.3 5.4 3.3 4.7 3.0 3.5 3.0 4.0 3.7 -3.2 4.0 3.4 3.5 2.6 2.9 4.1 3.0 4.4 3.5 3.6 3.8 4.7 1.1 3.8 4.8
Arm predicted mass (left) 2.1 10.9 24.3 4.9 3.7 4.8 2.9 3.0 2.8 4.0 3.3 -2.4 3.2 3.0 3.4 2.6 2.6 3.7 2.2 3.0 2.9 3.4 2.6 4.1 0.7 3.2 4.0