Best TWAS P=1.26e-15 · Best GWAS P=1.19e-18 conditioned to 0.0197
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | GRB14 | 0.14 | 0.09 | lasso | 7 | 0.06 | 0.00016 | 7.8 | -8.0 | 1.3e-15 | -0.46 | 0.28 | 0.43 | TRUE |
| 2 | GTEx | Thyroid | COBLL1 | 0.07 | 0.05 | lasso | 3 | 0.05 | 0.00015 | -6.1 | 6.2 | 7.5e-10 | 0.59 | 0.57 | 0.25 | TRUE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | GRB14 | 0.09 | 0.01 | blup | 82 | 0.03 | 0.00464 | 7.1 | -6.6 | 3.7e-11 | -0.54 | 0.02 | 0.64 | FALSE |