Best TWAS P=1.44e-10 · Best GWAS P=1.08e-10 conditioned to 0.107
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Coronary | CTNNB1 | 0.30 | 0.00 | lasso | 4 | 0.01 | 1.0e-01 | 6.3 | -5.9 | 4.5e-09 | -0.93 | 0.03 | 0.52 | FALSE |
2 | GTEx | Nerve Tibial | CTNNB1 | 0.05 | 0.00 | enet | 4 | 0.00 | 2.0e-01 | 6.1 | 6.2 | 5.7e-10 | 0.69 | 0.04 | 0.72 | FALSE |
3 | NTR | Blood | CTNNB1 | 0.04 | 0.04 | lasso | 6 | 0.04 | 4.6e-13 | 6.2 | -6.4 | 1.4e-10 | -0.89 | 0.02 | 0.98 | TRUE |