[Hub]/) : Traits : Trunk fat mass :

chr3:182,655,858-184,256,798

Best TWAS P=5.58e-11 · Best GWAS P=5.98e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KLHL24 0.42 0.60 bslmm 493 0.66 4.5e-107 -6.1 -6.1 1.2e-09 0.93 0.02 0.98 FALSE
2 GTEx Adipose Subcutaneous KLHL24 0.15 0.10 lasso 6 0.10 1.4e-08 -6.2 6.5 5.6e-11 -0.99 0.02 0.98 TRUE
3 GTEx Brain Caudate basal ganglia KLHL24 0.22 0.21 lasso 3 0.19 3.5e-06 -6.2 6.2 6.1e-10 -1.00 0.02 0.96 FALSE
4 GTEx Brain Cerebellar Hemisphere KLHL24 0.31 0.10 enet 22 0.09 3.4e-03 -6.2 5.5 2.8e-08 -0.77 0.02 0.92 FALSE
5 GTEx Brain Cerebellum KLHL24 0.52 0.14 enet 26 0.16 1.9e-05 -6.2 6.2 6.9e-10 -0.89 0.02 0.97 FALSE
6 GTEx Brain Cortex KLHL24 0.21 0.15 lasso 3 0.07 6.1e-03 -6.2 6.5 9.4e-11 -0.98 0.02 0.93 FALSE
7 GTEx Brain Frontal Cortex BA9 KLHL24 0.36 0.23 lasso 6 0.15 9.3e-05 -6.1 5.8 8.4e-09 -0.94 0.02 0.96 FALSE
8 GTEx Brain Hypothalamus KLHL24 0.22 0.24 lasso 2 0.19 3.3e-05 -5.3 5.2 1.5e-07 -0.70 0.05 0.69 FALSE
9 GTEx Breast Mammary Tissue KLHL24 0.25 0.13 lasso 5 0.11 3.4e-06 -6.2 6.3 3.4e-10 -0.98 0.02 0.98 FALSE
10 GTEx Breast Mammary Tissue (Female) KLHL24 0.25 0.19 lasso 14 0.16 2.3e-05 -4.8 5.2 2.0e-07 -0.77 0.03 0.94 FALSE
11 GTEx Esophagus Muscularis KLHL24 0.10 0.12 lasso 1 0.09 4.4e-06 -6.2 6.2 6.0e-10 -1.00 0.02 0.98 FALSE
12 GTEx Lung YEATS2-AS1 0.13 0.03 enet 27 0.07 3.3e-06 5.4 -5.2 2.7e-07 0.56 0.17 0.72 FALSE
13 GTEx Nerve Tibial KLHL24 0.08 0.06 lasso 3 0.05 1.5e-04 -6.1 6.1 9.5e-10 -0.98 0.02 0.96 FALSE
14 GTEx Skin Sun Exposed Lower leg KLHL24 0.09 0.06 lasso 10 0.05 9.5e-05 -6.2 6.1 9.3e-10 -0.99 0.02 0.98 FALSE
15 GTEx Testis KLHL24 0.17 0.10 lasso 4 0.10 4.0e-05 -6.2 6.2 6.1e-10 -1.00 0.02 0.98 FALSE
16 METSIM Adipose KLHL24 0.07 0.06 lasso 3 0.05 2.4e-08 -5.2 5.1 3.0e-07 -0.87 0.04 0.96 FALSE
17 METSIM Adipose MAP6D1 0.06 0.05 bslmm 473 0.06 2.3e-09 5.4 5.2 2.0e-07 -0.17 0.92 0.08 FALSE
18 YFS Blood KLHL24 0.02 0.01 lasso 2 0.01 1.4e-03 -5.2 5.4 6.1e-08 -0.89 0.03 0.97 FALSE
19 The Cancer Genome Atlas Brain Lower Grade Glioma ECE2 0.04 0.02 blup 61 0.03 3.5e-04 4.4 5.1 3.1e-07 -0.16 0.01 0.88 TRUE
20 The Cancer Genome Atlas Brain Lower Grade Glioma KLHL24 0.05 0.05 blup 53 0.05 1.1e-06 -6.1 6.0 1.9e-09 -0.94 0.02 0.98 FALSE
21 The Cancer Genome Atlas Prostate Adenocarcinoma KLHL24 0.03 0.04 enet 5 0.04 5.1e-05 -6.1 5.5 5.1e-08 -0.97 0.02 0.97 FALSE
22 The Cancer Genome Atlas Testicular Germ Cell Tumors KLHL24 0.16 0.16 blup 53 0.21 4.3e-08 -6.1 5.8 6.2e-09 -0.95 0.02 0.98 FALSE
23 The Cancer Genome Atlas Thyroid Carcinoma KLHL24 0.10 0.09 blup 53 0.09 1.7e-09 -5.7 5.5 4.3e-08 -0.93 0.02 0.98 FALSE