[Hub]/) : Traits : Trunk fat mass :

chr3:153,142,317-154,733,231

Best TWAS P=7.92e-10 · Best GWAS P=1.57e-11 conditioned to 0.000219

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DHX36 0.05 0.06 blup 357 0.05 1.3e-06 -5.1 -6.0 1.6e-09 0.58 0.94 0.06 FALSE
2 GTEx Adipose Subcutaneous ARHGEF26 0.10 0.06 enet 8 0.07 2.2e-06 -5.1 5.5 3.7e-08 -0.56 0.88 0.10 FALSE
3 GTEx Ovary ARHGEF26 0.14 0.03 enet 15 0.06 1.4e-02 4.8 6.0 1.6e-09 -0.53 0.10 0.30 FALSE
4 GTEx Pancreas ARHGEF26 0.26 0.26 lasso 5 0.28 3.2e-12 -4.8 5.8 8.2e-09 -0.62 0.98 0.02 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic ARHGEF26 0.13 0.11 lasso 4 0.07 6.8e-05 -4.8 5.5 4.7e-08 -0.60 0.87 0.08 FALSE
6 GTEx Spleen DHX36 0.39 0.09 enet 21 0.34 2.1e-09 -3.7 -5.8 6.1e-09 0.58 0.83 0.07 FALSE
7 GTEx Thyroid ARHGEF26 0.09 0.07 enet 17 0.08 1.9e-06 -5.0 5.8 5.8e-09 -0.62 0.20 0.78 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SGEF 0.04 0.04 enet 12 0.04 1.1e-05 -5.1 6.2 7.9e-10 -0.63 0.06 0.92 TRUE
9 The Cancer Genome Atlas Brain Lower Grade Glioma DHX36 0.11 0.09 enet 11 0.10 6.4e-12 -4.7 -5.2 2.6e-07 0.38 0.08 0.90 FALSE