[Hub]/) : Traits : Trunk fat mass :

chr4:47,802,595-53,598,975

Best TWAS P=2.02e-11 · Best GWAS P=1.83e-10 conditioned to 0.284

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SGCB 0.02 0.02 enet 21 0.01 9.7e-03 5.6 5.3 1.2e-07 0.69 0.05 0.84 FALSE
2 GTEx Brain Cerebellum OCIAD1 0.10 0.04 lasso 5 0.02 1.1e-01 5.2 -5.3 1.3e-07 -0.50 0.07 0.36 FALSE
3 GTEx Breast Mammary Tissue DCUN1D4 0.08 0.02 enet 11 0.04 2.4e-03 6.2 5.9 3.1e-09 0.89 0.04 0.89 FALSE
4 GTEx Breast Mammary Tissue (Female) DCUN1D4 0.02 0.03 lasso 1 0.02 8.2e-02 6.2 6.2 6.5e-10 0.96 0.02 0.21 FALSE
5 GTEx Cells Transformed fibroblasts DCUN1D4 0.05 0.04 enet 15 0.04 7.8e-04 5.6 5.5 3.2e-08 0.85 0.06 0.88 FALSE
6 GTEx Colon Transverse OCIAD1 0.07 0.07 lasso 5 0.05 2.8e-03 5.3 -5.2 2.6e-07 -0.44 0.18 0.67 FALSE
7 GTEx Esophagus Mucosa OCIAD1 0.07 0.06 lasso 4 0.06 9.9e-05 5.7 -5.2 1.7e-07 -0.44 0.10 0.90 FALSE
8 GTEx Esophagus Muscularis OCIAD1 0.12 0.16 lasso 6 0.17 9.1e-11 5.3 -5.2 2.0e-07 -0.46 0.13 0.87 FALSE
9 GTEx Nerve Tibial DCUN1D4 0.10 0.09 lasso 3 0.10 6.8e-08 5.6 6.0 1.5e-09 0.93 0.09 0.91 FALSE
10 GTEx Ovary FRYL 0.12 -0.01 enet 21 0.03 7.2e-02 5.5 5.9 3.1e-09 0.62 0.07 0.52 FALSE
11 GTEx Skin Sun Exposed Lower leg FRYL 0.05 0.01 enet 19 0.02 8.6e-03 -3.8 5.4 7.5e-08 0.45 0.17 0.53 FALSE
12 GTEx Testis DCUN1D4 0.19 0.17 enet 14 0.16 8.7e-08 5.6 5.7 1.1e-08 0.84 0.10 0.90 FALSE
13 GTEx Thyroid DCUN1D4 0.03 0.05 lasso 1 0.04 2.4e-04 6.2 6.2 6.5e-10 0.96 0.03 0.93 FALSE
14 ROSMAP Brain Pre-frontal Cortex SGCB 0.03 0.03 enet 9 0.03 7.0e-05 5.8 6.7 2.0e-11 0.87 0.04 0.95 TRUE
15 The Cancer Genome Atlas Colon Adenocarcinoma LRRC66 0.07 0.03 lasso 3 0.05 8.0e-04 5.6 -5.6 2.2e-08 -0.62 0.03 0.41 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma FRYL 0.03 0.03 enet 8 0.03 3.2e-04 5.2 5.6 2.5e-08 0.40 0.04 0.84 FALSE
17 The Cancer Genome Atlas Thyroid Carcinoma FRYL 0.02 0.01 blup 93 0.01 3.6e-02 5.1 5.3 1.1e-07 0.49 0.03 0.74 FALSE