Best TWAS P=7.71e-09 · Best GWAS P=8.31e-09 conditioned to 7.14e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | FBXL18 | 0.20 | 0.08 | lasso | 2 | 0.07 | 2.5e-04 | 5.2 | 5.2 | 2.6e-07 | -0.06 | 0.00 | 0.99 | FALSE |
| 2 | GTEx | Artery Aorta | ZDHHC4 | 0.29 | 0.09 | enet | 19 | 0.13 | 7.5e-08 | 4.1 | -5.8 | 7.7e-09 | -0.27 | 0.82 | 0.12 | TRUE |
| 3 | GTEx | Esophagus Mucosa | FBXL18 | 0.16 | 0.12 | lasso | 2 | 0.11 | 8.2e-08 | 5.2 | 5.2 | 2.4e-07 | -0.11 | 0.00 | 1.00 | FALSE |
| 4 | GTEx | Esophagus Mucosa | AC092171.4 | 0.14 | 0.07 | lasso | 3 | 0.05 | 3.2e-04 | 5.2 | 5.3 | 1.2e-07 | -0.10 | 0.00 | 1.00 | FALSE |
| 5 | METSIM | Adipose | FBXL18 | 0.08 | 0.06 | lasso | 3 | 0.05 | 1.6e-07 | 5.2 | 5.3 | 9.7e-08 | -0.10 | 0.00 | 1.00 | TRUE |