[Hub]/) : Traits : Trunk fat mass :

chr7:2,032,803-3,581,391

Best TWAS P=5.49e-29 · Best GWAS P=5.41e-26 conditioned to 0.28

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex AMZ1 0.19 0.12 enet 22 0.13 5.7e-16 7.1 8.3 7.0e-17 -0.43 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous GNA12 0.11 0.08 lasso 4 0.07 1.3e-06 -5.2 -6.2 7.7e-10 0.76 0.08 0.92 FALSE
3 GTEx Artery Tibial GNA12 0.24 0.13 enet 20 0.22 3.5e-17 -10.2 -8.3 8.4e-17 0.84 0.03 0.97 FALSE
4 GTEx Cells EBV-transformed lymphocytes GNA12 0.46 0.51 lasso 5 0.50 7.9e-19 -10.5 -10.4 2.0e-25 0.99 0.00 1.00 FALSE
5 GTEx Cells Transformed fibroblasts GNA12 0.21 0.11 lasso 11 0.15 1.7e-11 -10.2 -7.7 1.5e-14 0.86 0.04 0.96 FALSE
6 GTEx Colon Sigmoid GNA12 0.14 0.05 lasso 3 0.03 3.6e-02 -4.9 -8.0 1.1e-15 0.87 0.02 0.92 FALSE
7 GTEx Esophagus Gastroesophageal Junction GNA12 0.20 0.12 lasso 6 0.12 3.4e-05 -5.2 -8.2 3.7e-16 0.86 0.03 0.96 FALSE
8 GTEx Esophagus Mucosa GNA12 0.16 0.13 lasso 3 0.13 3.0e-09 -9.4 -8.3 7.8e-17 0.87 0.07 0.93 FALSE
9 GTEx Esophagus Muscularis GNA12 0.32 0.31 lasso 3 0.34 2.1e-21 -10.2 -9.9 3.5e-23 0.94 0.02 0.98 FALSE
10 GTEx Lung GNA12 0.16 0.08 enet 21 0.12 1.2e-09 -9.3 -7.4 1.4e-13 0.78 0.02 0.98 FALSE
11 GTEx Nerve Tibial GNA12 0.31 0.34 lasso 7 0.36 9.6e-27 -5.2 -7.5 5.9e-14 0.86 0.71 0.29 FALSE
12 GTEx Skin Sun Exposed Lower leg GNA12 0.17 0.16 lasso 3 0.18 1.3e-14 -5.3 -7.6 3.5e-14 0.87 0.15 0.85 FALSE
13 GTEx Small Intestine Terminal Ileum GNA12 0.34 0.20 lasso 5 0.16 2.4e-04 -5.1 -5.7 1.3e-08 0.72 0.05 0.83 FALSE
14 GTEx Stomach GNA12 0.18 0.16 lasso 2 0.13 6.6e-07 -4.9 -5.1 3.0e-07 0.70 0.20 0.79 FALSE
15 GTEx Whole Blood GNA12 0.09 0.01 enet 4 0.00 3.3e-01 -10.1 -10.4 1.9e-25 0.94 0.02 0.92 FALSE
16 METSIM Adipose GNA12 0.07 0.05 lasso 3 0.05 3.3e-08 -5.1 -5.2 2.6e-07 0.72 0.19 0.81 FALSE
17 NTR Blood GNA12 0.07 0.03 bslmm 597 0.06 1.3e-17 -6.5 -7.5 5.8e-14 0.63 0.89 0.11 FALSE
18 ROSMAP Brain Pre-frontal Cortex AMZ1 0.09 0.05 lasso 6 0.04 2.4e-06 -10.2 11.2 5.5e-29 -0.90 0.06 0.94 TRUE
19 YFS Blood GNA12 0.23 0.15 bslmm 570 0.25 4.5e-82 6.7 -7.7 1.8e-14 0.52 1.00 0.00 FALSE
20 The Cancer Genome Atlas Esophageal Carcinoma AMZ1 0.18 0.05 blup 69 0.05 1.4e-02 6.3 -9.5 1.5e-21 0.71 0.01 0.71 FALSE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GNA12 0.03 0.04 lasso 1 0.04 3.0e-05 -5.2 -5.2 1.9e-07 0.72 0.08 0.77 FALSE
22 The Cancer Genome Atlas Brain Lower Grade Glioma AMZ1 0.04 0.04 lasso 3 0.02 1.3e-03 6.3 7.2 6.7e-13 -0.60 0.04 0.90 FALSE
23 The Cancer Genome Atlas Lung Adenocarcinoma GNA12 0.03 0.01 enet 7 0.02 1.5e-03 3.5 -8.1 4.3e-16 0.78 0.06 0.76 FALSE