[Hub]/) : Traits : Trunk fat mass :

chr8:21,249,296-22,666,279

Best TWAS P=4.21e-08 · Best GWAS P=5.67e-08 conditioned to 0.445

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts NUDT18 0.10 0.04 enet 6 0.03 4.7e-03 5.0 5.4 5.2e-08 0.89 0.01 0.92 FALSE
2 GTEx Cells Transformed fibroblasts AC091171.1 0.15 0.06 lasso 2 0.05 2.2e-04 -5.3 5.2 1.8e-07 0.69 0.02 0.96 FALSE
3 GTEx Esophagus Mucosa FAM160B2 0.15 0.05 enet 19 0.09 1.7e-06 5.2 5.1 2.7e-07 0.77 0.01 0.98 FALSE
4 GTEx Esophagus Mucosa AC091171.1 0.14 0.07 lasso 4 0.05 2.2e-04 5.4 5.5 4.2e-08 0.94 0.01 0.99 TRUE
5 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma NUDT18 0.09 0.03 blup 45 0.08 1.3e-04 -5.1 -5.2 1.7e-07 -0.78 0.03 0.95 FALSE
6 The Cancer Genome Atlas Colon Adenocarcinoma FAM160B2 0.06 0.07 lasso 1 0.06 2.3e-04 5.2 5.2 1.6e-07 0.93 0.01 0.92 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma NUDT18 0.11 0.22 lasso 6 0.22 3.6e-24 -5.3 -5.2 1.9e-07 -0.78 0.02 0.98 FALSE
8 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma NUDT18 0.15 0.17 lasso 4 0.12 2.3e-04 -5.2 -5.4 7.7e-08 -0.78 0.02 0.95 FALSE