Best TWAS P=7.14e-11 · Best GWAS P=1.34e-11 conditioned to 0.972
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SLC25A37 | 0.08 | 0.05 | lasso | 5 | 0.05 | 4.8e-07 | -4.8 | 5.2 | 2.3e-07 | -0.74 | 0.16 | 0.84 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | SLC25A37 | 0.13 | 0.05 | lasso | 5 | 0.04 | 3.0e-04 | -6.8 | 6.5 | 7.1e-11 | -0.86 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | SLC25A37 | 0.11 | 0.09 | lasso | 5 | 0.09 | 7.8e-10 | -5.2 | -5.8 | 7.3e-09 | 0.59 | 0.92 | 0.08 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | LOXL2 | 0.16 | 0.03 | lasso | 4 | 0.05 | 1.2e-03 | -5.1 | 6.2 | 6.9e-10 | -0.59 | 0.02 | 0.76 | TRUE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CHMP7 | 0.03 | 0.03 | blup | 89 | 0.01 | 3.8e-02 | 3.9 | -5.8 | 5.4e-09 | 0.10 | 0.03 | 0.37 | TRUE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | CHMP7 | 0.10 | 0.02 | lasso | 6 | 0.04 | 5.4e-05 | 3.9 | -5.3 | 1.2e-07 | 0.18 | 0.02 | 0.91 | FALSE |