[Hub]/) : Traits : Trunk fat-free mass : ← →

chr6:79,927,081-81,872,212

Best TWAS P=3.59e-24 · Best GWAS P=1.52e-19 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	GTEx	Heart Atrial Appendage	RP11-250B2.6	0.20	0.00	enet	17	0.03	2.6e-02	-4.7	-10.1	3.6e-24	-0.41	0.05	0.48	TRUE
5	GTEx	Brain Cerebellum	RP11-250B2.5	0.43	0.11	lasso	5	0.14	4.7e-05	-8.2	-8.2	1.7e-16	-0.76	0.08	0.82	TRUE
21	GTEx	Thyroid	BCKDHB	0.17	0.06	lasso	8	0.10	3.4e-08	5.6	7.4	1.2e-13	0.46	0.98	0.02	TRUE
11	GTEx	Esophagus Muscularis	BCKDHB	0.18	0.07	enet	25	0.06	2.4e-04	6.1	5.8	5.1e-09	0.15	0.94	0.01	TRUE
9	GTEx	Colon Transverse	RP11-250B2.5	0.13	0.02	enet	3	0.01	6.3e-02	-2.9	-5.8	5.9e-09	-0.61	0.06	0.48	TRUE
3	GTEx	Artery Aorta	ELOVL4	0.11	0.13	lasso	2	0.11	1.7e-06	5.4	5.4	8.0e-08	0.45	0.94	0.00	TRUE
25	ROSMAP	Brain Pre-frontal Cortex	BCKDHB	0.18	0.13	lasso	6	0.14	2.9e-17	6.2	5.3	1.3e-07	0.18	1.00	0.00	TRUE
27	The Cancer Genome Atlas	Testicular Germ Cell Tumors	BCKDHB	0.19	0.02	blup	137	0.06	2.6e-03	6.1	5.2	1.5e-07	0.02	0.03	0.05	TRUE
20	GTEx	Testis	RP11-250B2.6	0.09	0.05	lasso	6	0.04	6.9e-03	5.6	-5.2	1.9e-07	-0.10	0.42	0.03	TRUE
7	GTEx	Cells Transformed fibroblasts	BCKDHB	0.16	0.02	enet	42	0.04	3.7e-04	5.5	9.0	1.6e-19	0.49	0.25	0.64	FALSE
16	GTEx	Muscle Skeletal	RP11-250B2.6	0.07	0.04	lasso	5	0.04	4.2e-05	8.7	-8.9	4.1e-19	-0.94	0.02	0.98	FALSE
10	GTEx	Esophagus Mucosa	RP11-250B2.6	0.20	0.16	lasso	7	0.23	3.3e-15	-8.0	-8.1	5.9e-16	-0.65	0.94	0.06	FALSE
1	GTEx	Adipose Visceral Omentum	RP11-250B2.6	0.16	0.05	lasso	6	0.06	7.8e-04	7.3	-8.0	1.2e-15	-0.57	0.22	0.44	FALSE
15	GTEx	Lung	RP11-250B2.6	0.09	0.05	enet	16	0.07	5.3e-06	5.6	-8.0	1.9e-15	-0.36	0.83	0.02	FALSE
19	GTEx	Testis	RP11-250B2.5	0.13	0.17	lasso	3	0.14	7.0e-07	-8.1	-7.8	4.0e-15	-0.88	0.04	0.96	FALSE
13	GTEx	Heart Left Ventricle	RP11-250B2.6	0.09	0.00	enet	6	0.02	2.0e-02	8.0	-7.6	2.6e-14	-0.82	0.06	0.68	FALSE
6	GTEx	Cells EBV-transformed lymphocytes	RP11-250B2.6	0.21	0.03	enet	37	0.13	4.7e-05	6.2	-7.2	5.6e-13	-0.23	0.14	0.07	FALSE
24	METSIM	Adipose	RP11-250B2.6	0.04	0.04	lasso	12	0.02	1.7e-04	7.8	-6.9	5.3e-12	-0.60	0.68	0.10	FALSE
26	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	BCKDHB	0.12	0.06	lasso	4	0.06	4.2e-07	6.9	-6.3	2.4e-10	-0.75	0.54	0.45	FALSE
17	GTEx	Nerve Tibial	BCKDHB	0.18	0.11	lasso	9	0.10	2.4e-07	6.2	6.2	4.7e-10	0.15	1.00	0.00	FALSE
14	GTEx	Lung	BCKDHB	0.09	0.06	enet	10	0.05	1.8e-04	6.1	6.1	9.8e-10	0.15	0.89	0.02	FALSE
2	GTEx	Artery Aorta	BCKDHB	0.14	0.14	lasso	1	0.13	9.8e-08	6.0	6.0	1.7e-09	0.15	1.00	0.00	FALSE
8	GTEx	Cells Transformed fibroblasts	RP11-250B2.6	0.11	0.01	lasso	7	0.00	1.4e-01	-8.0	-5.9	3.4e-09	-0.51	0.35	0.09	FALSE
4	GTEx	Artery Tibial	BCKDHB	0.16	0.16	lasso	11	0.15	4.9e-12	6.2	5.8	5.0e-09	0.15	1.00	0.00	FALSE
22	GTEx	Thyroid	RP11-250B2.6	0.11	0.10	lasso	2	0.07	3.2e-06	5.5	-5.5	3.4e-08	-0.13	1.00	0.00	FALSE
23	METSIM	Adipose	BCKDHB	0.05	0.03	blup	558	0.05	1.1e-07	-8.1	5.5	3.7e-08	0.55	0.88	0.12	FALSE
18	GTEx	Skin Not Sun Exposed Suprapubic	RP11-250B2.6	0.08	0.05	lasso	4	0.01	8.1e-02	5.6	-5.2	2.5e-07	-0.07	0.21	0.11	FALSE