[Hub]/) : Traits : Trunk fat-free mass :

chr6:129,638,583-132,080,991

Best TWAS P=1.94e-76 · Best GWAS P=7.74e-69 conditioned to 0.874

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous L3MBTL3 0.20 0.08 lasso 4 0.09 1.1e-07 17.5 18.1 2.0e-73 0.94 0.00 1.00 FALSE
2 GTEx Adipose Visceral Omentum L3MBTL3 0.14 0.12 lasso 2 0.15 2.8e-08 17.5 18.3 3.9e-75 0.94 0.00 1.00 FALSE
3 GTEx Breast Mammary Tissue L3MBTL3 0.31 0.25 lasso 7 0.23 2.8e-12 17.5 18.1 1.6e-73 0.97 0.00 1.00 FALSE
4 GTEx Breast Mammary Tissue RP11-73O6.3 0.27 0.22 lasso 9 0.22 1.5e-11 17.5 17.9 1.6e-71 0.97 0.00 1.00 FALSE
5 GTEx Breast Mammary Tissue (Male) L3MBTL3 0.31 0.24 lasso 6 0.23 5.5e-06 17.5 18.2 2.5e-74 0.94 0.01 0.98 FALSE
6 GTEx Breast Mammary Tissue (Male) RP11-73O6.3 0.33 0.17 lasso 4 0.12 1.3e-03 17.5 17.1 1.6e-65 0.94 0.01 0.95 FALSE
7 GTEx Breast Mammary Tissue (Female) L3MBTL3 0.30 0.13 lasso 5 0.14 4.5e-05 13.2 17.7 6.1e-70 0.93 0.01 0.98 FALSE
8 GTEx Breast Mammary Tissue (Female) RP11-73O6.3 0.29 0.08 lasso 5 0.10 5.7e-04 14.9 17.6 1.2e-69 0.90 0.01 0.96 FALSE
9 GTEx Cells EBV-transformed lymphocytes L3MBTL3 0.28 0.08 lasso 10 0.03 4.4e-02 17.5 17.0 8.3e-65 0.85 0.01 0.96 FALSE
10 GTEx Colon Transverse L3MBTL3 0.27 0.13 lasso 8 0.20 8.0e-10 17.5 17.7 3.7e-70 0.88 0.00 1.00 FALSE
11 GTEx Colon Transverse RP11-73O6.3 0.19 0.09 lasso 2 0.06 1.2e-03 17.5 18.0 1.7e-72 0.99 0.00 1.00 FALSE
12 GTEx Esophagus Mucosa L3MBTL3 0.26 0.18 lasso 2 0.23 2.7e-15 14.9 17.5 2.0e-68 0.93 0.00 1.00 FALSE
13 GTEx Lung L3MBTL3 0.37 0.34 lasso 4 0.38 4.1e-30 17.5 18.4 1.4e-75 0.96 0.00 1.00 FALSE
14 GTEx Lung RP11-73O6.3 0.15 0.08 lasso 5 0.12 2.2e-09 17.5 18.3 9.6e-75 0.93 0.00 1.00 FALSE
15 GTEx Nerve Tibial L3MBTL3 0.30 0.23 lasso 4 0.22 2.3e-15 17.5 18.2 7.6e-74 0.99 0.00 1.00 FALSE
16 GTEx Pancreas L3MBTL3 0.32 0.17 lasso 4 0.23 4.4e-10 17.5 18.3 9.4e-75 0.98 0.00 1.00 FALSE
17 GTEx Pituitary L3MBTL3 0.45 0.31 lasso 8 0.29 5.1e-08 13.2 15.6 6.1e-55 0.85 0.01 0.99 FALSE
18 GTEx Pituitary RP11-73O6.3 0.48 0.07 lasso 7 0.16 8.2e-05 13.2 13.3 2.3e-40 0.78 0.01 0.97 FALSE
19 GTEx Prostate L3MBTL3 0.35 0.27 lasso 5 0.17 5.9e-05 17.5 17.9 9.8e-72 0.97 0.00 0.99 FALSE
20 GTEx Skin Not Sun Exposed Suprapubic L3MBTL3 0.26 0.12 lasso 4 0.12 4.0e-07 13.8 17.2 1.4e-66 0.92 0.00 1.00 FALSE
21 GTEx Skin Sun Exposed Lower leg L3MBTL3 0.25 0.25 lasso 9 0.24 1.4e-19 17.5 17.8 8.6e-71 0.97 0.00 1.00 FALSE
22 GTEx Small Intestine Terminal Ileum L3MBTL3 0.37 0.20 lasso 4 0.17 1.3e-04 17.5 18.1 5.9e-73 0.98 0.00 0.98 FALSE
23 GTEx Spleen L3MBTL3 0.64 0.34 enet 14 0.48 6.4e-14 14.9 17.9 1.3e-71 0.87 0.02 0.98 FALSE
24 GTEx Spleen RP11-73O6.3 0.45 0.43 enet 21 0.42 7.7e-12 14.9 16.6 1.3e-61 0.82 0.06 0.94 FALSE
25 GTEx Stomach L3MBTL3 0.36 0.18 enet 27 0.20 1.1e-09 17.1 16.9 2.1e-64 0.77 0.02 0.98 FALSE
26 GTEx Stomach RP11-73O6.3 0.21 0.12 lasso 6 0.06 5.9e-04 17.1 17.1 3.0e-65 0.73 0.07 0.76 FALSE
27 GTEx Testis L3MBTL3 0.41 0.22 lasso 8 0.30 9.2e-14 17.5 17.0 1.4e-64 0.90 0.00 1.00 FALSE
28 GTEx Thyroid L3MBTL3 0.40 0.39 enet 9 0.43 2.8e-35 17.5 18.5 1.9e-76 0.95 0.00 1.00 TRUE
29 GTEx Thyroid RP11-73O6.3 0.18 0.15 lasso 3 0.20 2.3e-15 16.0 18.2 2.2e-74 0.91 0.00 1.00 FALSE
30 GTEx Whole Blood L3MBTL3 0.22 0.20 lasso 9 0.20 5.1e-18 17.5 18.0 9.5e-73 0.98 0.00 1.00 FALSE
31 GTEx Whole Blood RP11-73O6.3 0.15 0.06 lasso 8 0.04 1.1e-04 17.5 18.0 1.0e-72 0.97 0.00 0.99 FALSE
32 METSIM Adipose L3MBTL3 0.13 0.12 enet 22 0.12 4.8e-18 14.9 13.6 2.2e-42 0.72 0.99 0.01 FALSE
33 ROSMAP Brain Pre-frontal Cortex EPB41L2 0.12 0.12 blup 522 0.10 6.5e-13 2.9 5.1 2.9e-07 0.00 0.94 0.00 TRUE
34 ROSMAP Brain Pre-frontal Cortex L3MBTL3 0.14 0.07 blup 609 0.08 3.8e-10 17.5 14.1 2.5e-45 0.72 0.00 1.00 FALSE
35 YFS Blood L3MBTL3 0.28 0.22 blup 614 0.27 1.2e-88 14.9 14.3 2.8e-46 0.74 1.00 0.00 FALSE
36 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma L3MBTL3 0.05 0.00 blup 114 0.01 1.0e-02 11.2 6.8 1.3e-11 0.33 0.02 0.25 FALSE
37 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma L3MBTL3 0.06 0.01 blup 114 0.04 4.0e-03 14.9 13.9 3.4e-44 0.77 0.02 0.83 FALSE