Best TWAS P=1.47e-08 · Best GWAS P=3.43e-10 conditioned to 0.000233
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | PSPH | 0.19 | 0.09 | lasso | 8 | 0.12 | 2.5e-14 | -5.8 | -5.4 | 6.5e-08 | 0.79 | 0.03 | 0.97 | FALSE |
2 | GTEx | Prostate | GBAS | 0.33 | 0.08 | lasso | 8 | 0.13 | 3.4e-04 | -2.6 | -5.7 | 1.5e-08 | 0.58 | 0.09 | 0.53 | TRUE |
3 | METSIM | Adipose | PSPH | 0.16 | 0.13 | lasso | 15 | 0.17 | 2.9e-25 | -5.8 | -5.3 | 9.3e-08 | 0.77 | 0.02 | 0.98 | FALSE |