[Hub]/) : Traits : Trunk fat-free mass :

chr7:71,935,903-73,789,730

Best TWAS P=8.35e-17 · Best GWAS P=7.63e-18 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DNAJC30 0.13 0.07 enet 32 0.07 2.7e-09 6.54 7.3 3.1e-13 0.36 1.00 0.00 TRUE
2 GTEx Adipose Subcutaneous MLXIPL 0.11 0.07 enet 16 0.07 1.6e-06 7.38 8.0 1.5e-15 0.70 0.55 0.44 TRUE
3 GTEx Adipose Visceral Omentum MLXIPL 0.16 0.02 lasso 3 0.03 7.8e-03 7.19 7.7 1.6e-14 0.67 0.70 0.21 FALSE
4 GTEx Adipose Visceral Omentum NSUN5 0.07 0.03 enet 11 0.04 4.0e-03 7.79 6.3 3.5e-10 0.48 0.07 0.13 FALSE
5 GTEx Cells Transformed fibroblasts MLXIPL 0.13 0.06 enet 6 0.09 2.2e-07 7.87 8.2 2.2e-16 0.77 0.45 0.55 FALSE
6 GTEx Heart Left Ventricle MLXIPL 0.14 0.00 enet 24 0.01 1.3e-01 0.34 5.7 1.6e-08 0.38 0.18 0.10 FALSE
7 GTEx Lung MLXIPL 0.10 0.07 enet 14 0.07 6.3e-06 7.38 5.8 6.2e-09 0.50 0.37 0.10 TRUE
8 GTEx Skin Not Sun Exposed Suprapubic MLXIPL 0.11 0.11 lasso 3 0.06 2.7e-04 7.87 7.7 1.4e-14 0.62 0.29 0.48 TRUE
9 GTEx Skin Sun Exposed Lower leg MLXIPL 0.12 0.09 lasso 4 0.06 6.1e-06 7.82 8.0 1.4e-15 0.69 0.70 0.28 FALSE
10 GTEx Spleen NCF1B 0.22 0.10 enet 9 0.08 5.1e-03 8.18 -8.3 8.4e-17 -0.88 0.02 0.66 TRUE
11 GTEx Testis MLXIPL 0.10 0.00 lasso 3 0.00 3.3e-01 5.33 7.2 5.1e-13 0.58 0.05 0.09 FALSE
12 GTEx Testis VPS37D 0.15 0.01 lasso 5 0.03 2.7e-02 -5.74 -6.2 4.9e-10 -0.33 0.13 0.05 TRUE
13 GTEx Thyroid MLXIPL 0.23 0.14 lasso 7 0.15 2.1e-11 7.38 8.3 1.0e-16 0.73 0.67 0.33 FALSE
14 METSIM Adipose BCL7B 0.10 0.02 enet 20 0.05 1.2e-07 7.19 5.3 1.0e-07 0.20 0.62 0.34 TRUE
15 METSIM Adipose MLXIPL 0.12 0.14 lasso 4 0.13 1.8e-19 7.82 8.2 3.0e-16 0.80 0.74 0.26 FALSE
16 The Cancer Genome Atlas Bladder Urothelial Carcinoma STX1A 0.03 0.02 lasso 1 0.01 2.9e-02 -5.87 -5.9 4.4e-09 -0.30 0.00 0.82 FALSE
17 The Cancer Genome Atlas Breast Invasive Carcinoma MLXIPL 0.06 0.05 lasso 2 0.05 5.1e-10 7.78 7.3 2.1e-13 0.77 0.12 0.88 FALSE
18 The Cancer Genome Atlas Lung Adenocarcinoma MLXIPL 0.04 0.03 lasso 1 0.02 2.3e-03 7.78 7.8 7.4e-15 0.83 0.02 0.54 FALSE
19 The Cancer Genome Atlas Prostate Adenocarcinoma MLXIPL 0.08 0.05 enet 4 0.05 5.3e-06 7.78 6.7 2.0e-11 0.70 0.04 0.86 FALSE
20 The Cancer Genome Atlas Soft Tissue Sarcoma TBL2 0.16 0.00 enet 5 0.09 5.1e-06 -1.12 -5.3 1.4e-07 -0.52 0.00 0.50 FALSE
21 The Cancer Genome Atlas Thyroid Carcinoma BCL7B 0.05 0.01 blup 5 0.03 1.3e-03 7.78 -7.5 4.5e-14 -0.93 0.00 0.63 FALSE