TWAS
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Usage
Models
Genes
Traits
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Traits
:
Trunk fat-free mass
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chr8:8,165,004-9,669,775
Best TWAS P=1.22e-08 · Best GWAS P=6.63e-08 conditioned to 0.25
8.2M
8.4M
8.6M
8.8M
9M
9.2M
9.4M
9.6M
0
2
4
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Bladder Urothelial Carcinoma
ERI1
0.05
0.01
blup
72
0.01
5.0e-02
5.4
-5.7
1.2e-08
-0.84
0
0.87
TRUE
1
GTEx
Cells Transformed fibroblasts
ERI1
0.34
0.35
lasso
7
0.35
1.9e-27
5.4
-5.3
1.3e-07
-0.97
0
1.00
FALSE