Hub : Genes

ERI1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0590 0.0240 1.1e-04 0.040 0.040 0.027 0.035 0.041 1.1e-05 1.1e-05 2.5e-04 3.5e-05 9.0e-06
2 GTEx Adipose Subcutaneous 0.0530 0.0280 4.2e-03 -0.002 NA -0.002 NA -0.003 5.9e-01 NA 5.5e-01 NA 7.4e-01
3 GTEx Artery Aorta 0.1070 0.0410 1.5e-04 0.085 NA 0.071 NA 0.097 2.0e-05 NA 9.8e-05 NA 5.1e-06
4 GTEx Artery Tibial 0.0516 0.0238 2.7e-03 0.024 NA 0.009 NA 0.013 5.4e-03 NA 6.3e-02 NA 3.2e-02
5 GTEx Cells Transformed fibroblasts 0.3370 0.0670 0.0e+00 0.349 NA 0.344 NA 0.353 3.8e-27 NA 1.3e-26 NA 1.9e-27
6 GTEx Esophagus Muscularis 0.1200 0.0410 3.4e-06 0.086 NA 0.085 NA 0.079 6.5e-06 NA 7.7e-06 NA 1.6e-05
7 GTEx Lung 0.1315 0.0452 5.3e-07 0.065 NA 0.044 NA 0.089 1.0e-05 NA 2.7e-04 NA 2.7e-07
8 GTEx Nerve Tibial 0.0661 0.0305 2.6e-03 0.009 NA 0.012 NA 0.010 7.5e-02 NA 4.2e-02 NA 5.7e-02
9 GTEx Pancreas 0.0770 0.0390 8.9e-03 0.005 NA 0.043 NA 0.028 1.9e-01 NA 6.6e-03 NA 2.3e-02
10 GTEx Testis 0.3020 0.1000 1.2e-03 -0.004 NA 0.012 NA 0.000 5.5e-01 NA 9.6e-02 NA 3.2e-01
11 GTEx Whole Blood 0.1480 0.0450 8.3e-05 0.072 NA 0.045 NA 0.070 3.6e-07 NA 5.1e-05 NA 5.3e-07
12 NTR Blood 0.0377 0.0125 6.7e-06 0.008 0.014 0.009 0.013 0.009 8.3e-04 1.2e-05 3.8e-04 3.6e-05 5.5e-04
13 TCGA Bladder Urothelial Carcinoma 0.0500 0.0350 7.1e-03 0.005 0.009 -0.001 NA 0.004 1.0e-01 5.0e-02 3.8e-01 NA 1.5e-01
14 TCGA Lung Adenocarcinoma 0.0571 0.0320 3.4e-05 0.044 0.040 0.026 NA 0.039 5.9e-06 1.5e-05 4.9e-04 NA 2.1e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.8 1.2 6.5 0.7 -2.6 -0.4 -0.5 -0.1 -0.7 -1.7 -0.4 -0.8 1.7 0.6 1.4 0.0 0.2
Bipolar Disorder or Schizophrenia 3.0 7.3 15.1 -0.9 -3.9 -3.2 -2.5 -2.6 -2.7 -3.7 -2.3 -3.4 3.3 0.3 2.8 -1.4 -2.0
Depressed Affect (Nagel 2018) 1.7 3.7 11.8 2.9 -0.9 1.1 2.2 1.5 2.4 1.7 0.0 0.2 -3.4 2.6 1.0 1.1 2.1
Depression (Nagel 2018) 2.4 3.6 16.0 4.0 -0.7 1.0 1.6 1.9 2.2 1.6 -0.1 0.4 -2.3 2.7 0.2 0.9 2.4
Intelligence (Savage-Jansen 2018) 0.2 0.6 2.3 0.1 0.6 1.5 0.7 0.6 0.8 1.0 1.1 0.7 0.3 0.6 -0.1 0.1 1.3
Neuroticism (Nagel 2018) 1.8 4.2 9.9 3.1 -0.2 0.8 2.5 1.2 2.6 2.0 -0.3 1.4 -3.0 3.1 0.9 1.0 2.6
Schizophrenia (2018) 3.8 7.9 14.5 -1.8 -2.9 -3.8 -2.8 -3.2 -2.9 -3.5 -2.7 -3.8 2.9 -0.2 2.5 -1.8 -2.7
Schizophrenia vs Biploar Disorder 2.5 3.3 7.8 -2.1 -1.4 -2.2 -1.8 -2.0 -1.8 -1.0 -2.3 -2.8 -0.0 -1.4 0.7 -1.8 -2.1
Worry (Nagel 2018) 0.7 1.5 3.3 1.5 0.3 0.0 1.8 0.0 1.5 1.2 -0.5 1.7 -1.8 1.7 -0.3 0.2 1.3
Alzheimer’s Disease (in mother) 0.5 0.6 3.2 0.1 -1.1 -0.7 -0.3 -0.5 -0.2 -0.9 -1.4 -1.8 0.1 0.1 0.4 -0.4 -0.0
Alzheimer’s Disease (in father) 0.6 0.7 3.8 1.0 0.8 0.1 -0.3 0.4 -0.1 0.2 0.3 1.0 0.3 1.3 1.9 -0.2 0.7
Alzheimer’s Disease (including proxy) 0.2 0.3 1.2 1.1 0.3 0.2 0.0 0.3 0.1 -0.3 -0.7 -0.5 -0.3 0.7 0.7 -0.3 0.6
Crohns Disease (2017) 0.3 0.7 3.9 0.3 -2.0 -0.2 -0.3 -0.4 -0.2 -0.8 -1.6 -1.2 0.0 -0.7 -0.1 -0.3 0.0
Irritable Bowel Disease (IBD) 0.4 1.0 4.8 -0.4 -0.9 -0.3 -0.3 -0.6 -0.3 0.1 -1.8 -1.0 -1.2 -2.2 -1.2 -0.8 -0.7
Ulcerative Colitis (UC) 0.7 1.3 6.6 -0.9 0.2 -0.4 -0.1 -0.6 -0.3 0.7 -1.3 -0.7 -1.8 -2.6 -1.6 -0.8 -0.9
Major Depression (MDD) 0.9 1.1 2.6 0.5 -0.9 1.0 1.3 1.2 1.3 -0.3 0.8 0.7 1.1 -0.9 -1.6 1.4 0.9
Reaction Time 0.3 0.5 2.0 0.7 -0.2 0.8 1.0 0.9 0.9 1.4 0.2 0.3 -0.6 -0.3 0.3 0.6 0.1
Verbal and Numeric Reasoning (VNR) 0.7 1.6 4.0 0.7 0.9 1.7 1.6 1.3 1.5 1.6 2.0 0.8 -0.8 0.9 -0.5 0.8 1.6
Breast Cancer 2.1 5.1 8.8 -2.0 -2.2 -2.6 -2.8 -2.4 -3.0 -2.5 -2.7 -1.5 1.0 -0.2 2.7 -2.5 -1.7
Ovarian Cancer 1.1 1.4 3.4 0.4 -0.6 -1.5 -1.3 -1.9 -1.0 -1.4 -1.4 -1.2 1.2 0.1 0.9 -1.2 -1.3
Prostate Cancer 1.8 2.6 6.4 0.6 -2.1 -2.0 -1.9 -1.4 -1.4 -1.7 -2.5 -2.4 -0.4 1.5 0.9 -0.9 -0.6
Age at First Birth 0.9 1.3 3.2 1.0 0.9 0.5 1.8 0.7 1.6 1.3 1.4 0.8 -1.8 0.5 -0.6 1.1 0.6
Bipolar Disorder (2011) 0.7 0.6 3.1 0.9 -1.8 0.1 -0.2 0.4 -0.1 -0.7 -0.1 -0.7 0.9 1.2 0.7 1.0 0.5
Body Mass Index (BMI) (2010) 2.4 3.3 8.0 -0.3 -2.2 -2.4 -1.6 -2.2 -1.6 -2.2 -1.7 -2.8 1.3 1.0 2.1 -1.2 -1.2
Coronary Artery Disease (CAD) 0.5 0.6 3.2 -1.4 -0.9 0.2 0.1 -0.4 -0.0 0.0 -0.5 -0.4 0.9 -1.8 0.3 0.0 -0.8
Crohns Disease (2012) 0.4 0.6 3.3 1.0 -1.8 0.3 -0.1 0.1 0.2 -0.3 -1.4 -1.1 -0.4 0.2 -0.0 -0.1 0.7
Mean Putamen Volume 1.0 1.1 3.5 0.2 -1.7 -0.8 -1.0 -0.4 -0.5 -0.2 -1.8 -1.4 -0.2 1.3 1.9 -0.4 0.2
Fasting Glucose 1.1 1.3 6.0 -1.8 -0.8 -0.3 -0.5 -0.8 -0.4 -0.9 -0.7 0.1 1.5 -2.4 -1.5 0.1 -1.3
HbA1C 1.2 1.3 4.4 -1.2 -0.8 -1.6 -1.1 -1.2 -1.1 -1.0 -2.1 -0.7 0.9 -1.1 0.1 -0.6 -1.2
HDL Cholesterol 0.6 1.0 2.3 1.3 -0.2 1.2 0.5 1.2 1.2 0.2 0.5 -0.6 0.9 1.5 0.5 1.2 1.5
LDL Cholesterol 1.5 2.4 5.8 -1.7 -1.7 -1.1 -1.5 -1.4 -1.6 -1.0 -1.5 -2.4 1.1 -1.3 2.2 -0.5 -1.6
Lupus 9.0 13.7 22.3 -2.3 -3.9 -3.6 -4.5 -3.9 -4.4 -4.3 -4.7 -4.4 3.6 -1.5 2.1 -3.3 -3.5
Neuroticism (2016) 23.3 33.6 57.9 5.2 4.1 6.8 7.5 6.7 7.6 7.2 5.4 5.7 -4.1 4.3 -2.6 5.0 6.4
Primary Biliary Cirrhosis 1.3 1.9 5.2 -0.8 -1.6 -1.6 -1.6 -1.3 -1.4 -2.2 -1.5 -0.9 2.3 -0.9 -0.5 0.2 -0.9
Rheumatoid Arthritis 0.2 0.3 1.2 0.4 -0.2 -0.7 -0.1 0.1 0.2 -0.1 -1.1 -0.5 0.3 0.5 0.9 0.3 0.4
Schizophrenia (2014) 4.7 10.4 16.3 -2.1 -4.0 -3.9 -3.2 -3.6 -3.2 -3.7 -3.4 -4.0 3.2 -0.7 3.0 -2.4 -3.0
Triglycerides 5.0 8.2 14.9 0.6 3.8 3.3 3.3 3.1 2.7 2.4 3.9 3.8 0.1 0.5 -3.0 3.3 2.5
Type 2 Diabetes (T2D) (2012) 1.0 1.2 2.2 -0.4 -1.1 -1.4 -1.3 -1.3 -1.4 -1.4 -1.0 -1.5 0.8 0.4 -0.1 -1.0 -1.0
Ulcerative Colitis 1.3 1.8 5.1 1.0 1.4 1.0 1.6 0.9 1.7 2.3 0.2 0.8 -2.2 -1.0 -1.9 0.8 0.4
Blood Eosinophil Count 0.2 1.9 4.4 -0.8 0.7 -1.9 -1.4 -2.0 -0.9 0.7 -0.1 1.9 1.2 -0.2 1.2 -1.9 -2.1
Blood Platelet Count 0.3 3.7 23.7 2.6 -1.4 -0.3 0.3 0.1 -0.1 2.2 0.2 0.1 -1.3 2.7 4.9 -2.2 1.2
Blood Red Count 0.6 6.2 16.1 -2.2 0.9 -2.6 -2.0 -3.7 -2.2 -2.4 -0.2 1.6 3.2 -2.5 -0.0 -4.0 -3.4
Blood White Count 0.2 1.6 5.4 1.6 -2.3 -0.2 -0.0 0.3 -0.0 1.9 -0.6 0.3 -1.1 1.6 2.3 -0.8 0.6
Heel T-Score 0.6 4.4 20.2 -0.8 2.9 -0.9 0.8 -1.1 0.8 -3.4 1.1 -0.4 4.5 -2.2 -3.1 0.4 -1.6
BMI 0.1 0.4 1.5 0.2 -0.5 0.2 -0.3 -0.7 -0.4 0.6 -0.2 0.2 -0.0 -0.9 0.9 -1.2 -0.7
Height 0.1 2.4 10.3 -0.5 1.6 -1.3 1.0 -1.5 -0.1 1.7 1.0 1.5 -2.9 1.2 0.2 -3.2 -0.4
Waist Hip Ratio (WHR) 0.3 1.5 6.7 1.3 -0.6 0.2 -0.5 0.4 -0.8 0.9 -1.0 2.2 -1.8 2.6 0.1 0.1 1.1
Systolic Blood Pressure 0.1 0.5 4.4 0.4 -0.7 0.4 -0.3 0.2 -0.9 -0.9 0.1 0.2 2.1 -0.2 0.4 0.2 -0.0
Smoking Status 0.4 0.9 5.4 2.3 -0.2 1.0 0.5 0.8 0.8 0.5 0.5 0.3 0.2 0.9 -1.1 0.8 1.1
Allergy or Eczema 0.2 0.5 2.3 -0.2 -0.1 -0.2 -0.0 -0.4 -0.2 -1.2 -0.7 1.5 -0.7 0.5 0.6 -1.1 0.3
Cardiovascular Disease 0.2 0.5 2.6 -0.2 -1.6 0.2 -0.7 -0.9 -0.6 -0.7 0.1 -0.2 0.2 -0.7 0.5 -1.0 -0.7
Hypothyroidism (self reported) 0.2 0.5 3.2 0.2 1.0 -0.1 0.3 -0.9 -0.6 0.2 -0.0 0.9 -0.1 0.1 0.6 -1.8 -0.3
Respiratory disease 0.9 2.0 11.8 1.4 0.4 0.2 -1.3 -0.1 -0.5 -2.0 -0.3 1.4 3.4 1.8 1.3 0.0 1.1
Type 2 Diabetes (T2D) (2018) 0.8 1.6 6.1 -1.2 1.3 -1.1 0.4 -1.2 -0.5 -0.5 0.2 0.8 -0.8 -2.0 -2.5 -0.7 -1.8
Lung FEV1/FVC ratio 0.6 2.8 18.7 1.7 1.7 -0.4 1.8 -0.2 1.9 2.4 0.7 0.5 -4.3 0.7 0.5 -0.4 0.6
Lung FVC 0.2 1.1 4.7 0.9 1.6 0.8 1.4 0.4 1.7 -0.7 0.3 -0.5 0.1 -0.3 -2.2 0.3 0.7
Neuroticism 0.5 1.2 4.8 1.3 -1.6 -0.6 0.7 -0.2 1.0 0.6 -1.5 0.8 -2.2 1.2 0.6 -0.2 0.6
Chronotype (morning person) 0.9 2.2 7.0 -1.8 -1.4 -1.9 -0.5 -2.1 -0.6 -0.4 -2.6 -0.5 1.5 -0.9 1.0 -1.0 -2.0
Hair Pigment 0.1 4.0 12.4 2.8 -0.6 1.2 2.0 1.9 2.2 0.8 -0.4 0.9 -3.5 3.0 -0.5 2.5 2.1
Tanning 0.1 0.9 3.7 -1.3 -0.9 0.7 -0.6 -0.1 -0.6 -1.3 0.2 -1.7 1.9 -1.1 0.0 0.1 -0.3
Hand grip strength (left) 0.3 0.8 3.0 0.6 1.0 -1.7 -0.9 -1.1 -0.5 -0.2 0.6 -0.2 -0.4 1.0 1.0 -1.2 0.3
Number of treatments/medications taken 0.9 1.6 6.8 -0.8 -2.6 -0.8 -1.0 -1.0 -0.9 -1.4 -1.9 -1.6 -0.0 -1.1 -0.6 0.2 -1.1
Average weekly spirits intake 0.6 0.8 2.5 0.6 0.6 1.6 1.2 0.9 1.1 1.5 0.6 0.9 -0.4 0.4 -0.1 0.5 0.8
Sensitivity / hurt feelings 15.2 26.0 35.5 5.1 4.0 5.4 5.5 5.7 5.9 5.2 5.3 6.0 -3.1 5.0 -2.3 5.6 5.9
Frequency of depressed mood in last 2 weeks 9.2 12.9 23.3 4.8 1.5 3.7 3.8 4.3 4.2 4.1 2.7 2.5 -3.8 3.8 -1.1 3.0 4.5
Hearing difficulty/problems: Yes 0.5 0.7 2.4 1.3 -0.9 0.4 1.5 0.6 0.9 0.3 0.2 0.2 -1.6 0.4 -0.6 0.5 0.6
Relative age of first facial hair 0.1 0.3 1.1 0.6 0.7 0.2 -0.5 0.3 -0.2 -0.3 0.7 0.7 0.5 1.0 0.0 -0.5 0.6
Other serious medical condition/disability diagnosed by doctor 0.5 0.7 3.1 1.6 -0.8 0.6 0.8 0.6 0.6 0.2 -0.2 -0.3 -1.8 0.5 -0.6 0.1 0.5
Ever used hormone-replacement therapy (HRT) 0.9 1.1 4.3 -0.7 -1.7 0.1 -1.1 -0.2 -1.0 -1.5 -2.1 -0.4 1.4 -0.2 -0.6 0.7 -0.3
Ever had hysterectomy (womb removed) 4.4 5.0 7.5 -1.8 -2.1 -2.6 -2.3 -2.4 -2.4 -2.6 -2.7 -2.5 1.9 -0.9 2.0 -1.8 -2.4
Systolic blood pressure, automated reading 8.9 26.0 42.9 -2.9 -6.0 -5.3 -6.0 -5.2 -6.2 -6.2 -6.5 -5.0 4.6 -2.8 3.3 -4.2 -4.9
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 1.2 0.7 -1.1 0.3 0.0 0.1 0.2 -0.5 -0.3 -0.7 1.0 0.5 -0.5 0.9 0.1
Angina 0.9 1.2 4.0 0.5 -1.7 -0.3 -0.7 -0.7 -0.8 -0.3 -1.4 -2.0 -1.1 1.5 1.0 -1.3 -0.2
Medication for hormone replacement therapy 1.0 1.2 3.4 -1.0 -1.8 -1.0 -1.0 -1.1 -1.6 -1.6 -1.3 -0.9 0.4 -0.0 -0.0 -0.5 -0.8
Vitamin and mineral supplements 1.7 2.3 6.4 1.0 2.5 1.3 1.9 1.2 1.9 1.9 2.1 1.1 -1.4 0.4 -1.4 0.6 1.0
Supplements: Zinc 2.1 2.3 4.7 -1.0 -1.8 -1.3 -2.2 -1.5 -2.1 -1.8 -2.1 -1.5 1.2 -0.1 1.2 -0.7 -1.1
Medication: Co-codamol 0.9 1.0 2.7 -0.6 -0.5 -1.6 -0.8 -1.2 -1.1 -1.0 -0.8 -1.4 -1.0 -0.6 0.2 -1.0 -1.1
Medication: Metformin 3.1 4.3 8.2 -2.0 -2.0 -2.5 -1.8 -2.6 -2.2 -2.8 -2.2 -1.5 1.0 -2.2 -0.5 -1.5 -2.9
Diabetes (father) 2.7 3.4 8.9 0.5 -1.5 -2.3 -2.4 -1.9 -2.3 -1.5 -2.0 -1.4 0.1 0.5 2.2 -3.0 -1.6
Diabetes (mother) 0.3 0.4 1.5 0.2 -0.2 -0.2 -0.9 -0.4 -0.4 -0.6 -1.0 -1.2 0.7 0.3 0.3 -0.5 -0.1
Severe depression (siblings) 0.5 0.6 5.4 0.6 -0.5 -0.6 -0.6 -0.3 -0.1 -0.5 -0.9 -0.8 -2.3 0.0 -0.0 -0.2 0.4
Pack years adult smoking proportion 1.8 2.7 7.7 -0.9 -2.3 -2.0 -2.2 -1.6 -1.6 -1.9 -2.8 -1.5 1.2 -0.6 -0.1 -1.0 -1.2
Impedance of leg (right) 11.9 57.5 81.0 7.0 7.4 8.8 8.6 9.0 8.9 8.3 8.0 7.7 -3.1 5.6 -4.6 7.9 8.5
Leg fat-free mass (left) 5.0 26.7 48.0 -4.5 -4.7 -6.3 -5.6 -6.8 -6.0 -4.9 -4.8 -4.3 1.0 -4.0 3.5 -6.9 -6.0
Trunk fat percentage 1.5 6.0 12.3 -1.5 -3.5 -2.4 -2.3 -3.0 -2.4 -2.3 -3.0 -1.9 1.6 -2.3 1.9 -2.6 -2.7
Hand grip strength (right) 0.4 1.1 3.8 0.0 1.5 -1.9 -0.7 -1.6 -0.6 -0.6 1.0 -0.0 -0.8 -0.4 0.3 -1.9 -0.4
Townsend deprivation index at recruitment 0.1 0.2 0.7 -0.2 -0.2 0.5 -0.1 -0.2 -0.1 0.2 -0.4 -0.4 -0.8 -0.6 -0.5 -0.3 -0.2
Current tobacco smoking 5.7 9.3 14.5 -1.1 -3.7 -3.8 -3.8 -3.4 -3.6 -3.6 -3.7 -3.5 1.6 -0.7 1.2 -3.1 -3.0
Average weekly fortified wine intake 2.2 2.6 6.7 0.6 1.9 1.9 1.1 2.0 1.1 1.7 2.0 2.6 0.1 1.1 -1.0 2.2 1.2
Maternal smoking around birth 0.2 0.4 2.6 -0.0 -0.2 0.5 0.5 0.1 -0.2 0.2 1.0 1.6 -0.2 0.7 -0.3 -0.4 -0.2
Fed-up feelings 11.7 21.3 36.3 4.6 2.8 5.3 5.5 5.4 6.0 5.4 4.1 3.8 -4.4 2.9 -3.4 4.6 4.9
Frequency of unenthusiasm / disinterest in last 2 weeks 5.3 7.0 16.5 4.1 1.8 2.7 2.4 3.0 3.1 3.3 1.5 2.3 -3.1 2.2 -1.7 1.6 3.1
Relative age voice broke 0.7 1.0 3.3 1.5 1.2 0.8 0.4 1.0 0.6 0.6 1.4 1.0 0.3 1.8 0.2 0.1 1.1
Taking other prescription medications 0.2 0.3 1.4 0.6 -0.5 0.2 0.2 0.3 -0.1 -0.6 -0.2 1.2 0.4 0.6 0.3 0.8 0.3
Age when periods started (menarche) 1.6 3.8 7.2 1.3 2.1 1.8 2.2 1.8 2.2 2.7 2.6 1.7 -2.6 1.3 -1.0 1.2 1.8
Bilateral oophorectomy (both ovaries removed) 1.1 1.2 4.0 -0.6 -1.5 -0.3 -1.0 -0.7 -0.7 -1.8 -2.0 -1.3 1.3 -0.9 0.3 -0.5 -0.9
Heel bone mineral density (BMD) T-score, automated (left) 22.3 50.5 94.9 -5.3 -7.5 -8.2 -8.1 -8.1 -8.1 -9.7 -7.8 -7.8 5.8 -3.8 3.5 -6.0 -6.9
Tinnitus: Yes, but not now, but have in the past 1.3 1.4 4.1 -0.4 -1.1 -1.3 -1.6 -1.0 -1.5 -0.9 -1.6 -2.0 -0.8 -0.2 1.5 -0.7 -0.7
Qualifications: CSEs or equivalent 0.2 0.3 0.8 -0.9 0.5 -0.0 0.3 -0.2 0.5 0.3 0.2 -0.0 0.7 -0.8 -0.8 0.7 0.0
Serious illness, injury or assault to yourself 1.5 1.8 4.9 0.9 0.0 1.7 1.9 1.4 1.9 2.2 1.1 0.1 -1.2 0.1 -1.6 0.9 1.1
High blood pressure 12.3 34.3 49.1 -4.2 -7.0 -6.7 -7.0 -7.0 -6.7 -6.8 -7.0 -5.5 3.0 -3.2 3.5 -5.7 -6.1
Hayfever, allergic rhinitis or eczema 0.4 0.9 2.1 -0.8 -0.6 -1.0 -0.5 -1.0 -0.7 -1.2 -0.8 1.3 -0.8 0.2 1.3 -1.4 -0.4
Multivitamins +/- minerals 0.5 0.7 3.0 0.6 -1.0 -0.5 -1.0 -0.4 -0.8 -0.8 -1.1 0.0 0.7 0.6 1.7 -0.5 0.3
Stomach or abdominal pain in last month 2.8 3.5 9.8 1.1 1.7 1.8 2.2 1.6 2.1 2.2 2.4 3.1 -1.5 1.1 -1.3 1.5 1.3
Supplements: Glucosamine 0.8 1.1 2.1 1.2 0.4 1.4 0.0 1.2 0.2 -0.5 1.0 1.4 1.3 1.2 0.2 1.4 1.3
Diverticular disease/diverticulitis (self-reported) 0.1 0.1 0.5 0.7 -0.1 0.1 0.1 0.2 0.2 -0.7 0.2 0.3 -0.2 -0.6 -0.1 0.0 -0.1
Medication: Atenolol 4.3 5.3 8.1 -2.1 -2.2 -2.1 -2.8 -2.8 -2.6 -2.4 -2.2 -2.5 1.2 -1.7 2.1 -2.5 -2.5
Medication: Levothyroxine sodium 9.2 15.6 26.1 3.0 4.6 4.5 4.9 3.9 4.5 5.1 5.1 5.0 -1.9 1.7 -2.0 3.0 3.6
Sitting height 3.0 21.5 42.4 -5.7 -3.2 -5.5 -3.8 -6.5 -5.0 -4.7 -2.5 -3.3 3.3 -4.7 1.7 -5.6 -6.2
Chronic bronchitis/emphysema (father) 0.2 0.3 0.9 0.7 0.7 -0.1 -0.3 0.5 -0.1 0.4 -0.6 0.5 -0.8 0.9 -0.2 0.3 0.3
High blood pressure (mother) 4.5 6.3 12.5 -2.8 -2.1 -2.7 -2.9 -3.2 -3.1 -2.0 -2.5 -0.7 0.1 -2.0 1.3 -3.5 -3.3
Body mass index (BMI) 10.5 44.8 64.2 -4.8 -7.5 -7.5 -7.6 -8.0 -7.6 -7.3 -7.8 -6.2 3.5 -4.9 4.6 -7.0 -7.2
Impedance of leg (left) 13.0 63.0 88.7 7.2 7.8 9.3 9.1 9.4 9.4 8.5 8.8 7.4 -2.8 5.6 -5.0 8.7 8.9
Leg predicted mass (left) 5.1 26.9 47.6 -4.5 -4.8 -6.3 -5.7 -6.8 -6.0 -5.0 -4.8 -4.3 1.0 -4.1 3.4 -6.9 -6.0
Trunk fat mass 2.7 11.4 19.1 -2.5 -4.1 -3.6 -3.4 -4.4 -3.6 -3.3 -3.6 -2.6 1.9 -3.2 2.2 -4.0 -3.9
Waist circumference 1.3 4.9 7.9 -1.6 -2.8 -2.3 -2.1 -2.8 -2.4 -2.3 -2.7 -1.4 0.7 -2.2 1.1 -2.5 -2.7
Number of incorrect matches in round 0.5 0.9 3.8 -1.5 0.7 0.5 -0.0 0.6 0.2 0.7 0.6 0.7 -0.3 -1.9 -1.9 0.8 -0.4
Past tobacco smoking 1.7 3.2 8.5 -0.2 2.9 1.4 2.0 2.0 1.9 2.0 2.1 1.9 -1.6 -0.3 -2.1 1.6 0.6
Alcohol usually taken with meals 4.7 7.7 15.8 -4.0 -2.4 -3.2 -2.4 -3.5 -2.7 -2.1 -2.7 -1.7 1.6 -3.2 1.0 -2.6 -3.8
Nervous feelings 18.2 33.9 51.4 4.5 6.1 6.5 7.0 6.1 7.2 6.6 6.5 6.7 -4.4 3.7 -3.8 4.8 6.1
Frequency of tenseness / restlessness in last 2 weeks 4.1 6.3 13.6 3.7 0.7 2.7 2.8 2.3 2.8 3.3 1.3 2.4 -3.3 3.0 -0.2 -0.0 3.0
Hearing difficulty/problems with background noise 1.9 3.0 6.6 2.3 0.0 2.2 1.9 2.6 1.9 0.7 1.3 1.0 -0.6 1.7 -0.5 2.5 2.3
Hair/balding pattern: Pattern 2 2.0 2.6 15.0 0.4 -1.7 -1.0 -2.0 -1.3 -1.3 -1.0 -1.1 -0.4 -0.3 2.1 3.9 -1.7 -0.1
Had menopause 0.7 0.9 3.2 0.6 -0.3 -0.2 -1.2 -0.2 -0.8 -1.1 -1.0 -0.7 1.8 0.9 1.6 0.5 0.1
Had other major operations 1.9 2.3 4.9 -0.5 -2.2 -1.5 -1.7 -1.7 -1.7 -1.7 -2.2 -0.7 0.8 -1.1 1.6 -1.4 -1.4
Forced vital capacity (FVC) 1.6 6.1 13.9 1.6 3.7 1.9 3.0 1.4 2.8 2.7 3.7 2.4 -3.7 0.9 -1.4 0.0 1.7
Heel bone mineral density (BMD) T-score, automated (right) 21.7 49.7 93.9 -4.8 -7.2 -8.6 -8.1 -8.1 -8.0 -9.7 -8.2 -7.6 5.5 -3.5 3.8 -5.7 -6.7
Ever unenthusiastic/disinterested for a whole week 0.5 0.7 3.0 1.1 -0.3 -0.5 0.4 -0.6 -0.0 0.7 -0.2 1.2 -1.7 0.6 0.7 -1.1 0.3
Qualifications: None of the above 0.3 0.7 2.2 -0.4 -1.5 -0.5 -0.5 -0.6 -0.4 -0.9 -1.2 -0.8 0.6 -1.2 -0.5 0.3 -1.2
Financial difficulties in last 2 years 1.0 1.4 4.2 -1.3 -1.1 -1.2 -0.8 -1.8 -0.9 -0.8 -0.9 -0.6 -0.2 -1.4 -1.0 -2.1 -1.3
Mouth/teeth dental problems 5.2 8.0 19.9 1.7 4.0 3.3 2.9 2.9 2.8 3.0 4.5 3.6 -1.3 1.6 -1.6 1.6 2.5
Heart attack 0.2 0.3 1.4 0.9 -0.4 0.4 0.4 0.1 0.1 0.3 -0.3 0.4 -0.4 1.2 0.1 0.5 0.3
Allergy 1.6 3.8 6.2 1.7 2.0 2.3 2.3 2.4 2.3 2.5 2.4 -0.1 0.0 0.2 -2.3 2.2 1.6
Pain all over the body in last month 2.6 2.8 4.7 -1.5 -1.6 -1.8 -1.4 -2.0 -1.6 -1.6 -2.0 -1.1 -0.1 -2.2 -1.2 -2.1 -2.2
Diabetes (self-reported) 1.6 2.5 6.0 -1.7 -1.0 -2.1 -1.2 -1.8 -1.7 -1.9 -1.4 -1.0 0.4 -2.1 -1.2 -1.1 -2.4
Hayfever/allergic rhinitis (self-reported) 1.8 2.4 10.9 0.5 1.3 1.2 2.0 1.4 1.7 1.1 1.9 3.3 -0.9 1.3 0.2 1.2 1.5
Medication: Ramipril 3.5 4.5 7.2 -1.9 -2.7 -1.8 -2.4 -2.4 -2.1 -1.9 -2.6 -2.2 1.0 -2.2 -0.9 -2.1 -2.5
Medication: Simvastatin 1.6 2.3 4.8 -0.8 -2.0 -1.1 -1.2 -1.8 -1.4 -1.4 -1.9 -2.0 0.8 -1.8 -0.5 -1.1 -2.2
Fluid intelligence score 0.7 1.4 2.7 1.0 1.2 1.6 1.4 1.2 1.4 1.5 1.2 0.8 -0.8 0.7 -0.7 0.8 1.5
Illnesses of siblings 2.7 3.7 8.1 1.9 2.1 2.0 1.8 2.1 1.7 2.8 2.3 1.8 -0.4 1.9 1.3 1.2 2.4
Neuroticism score 24.8 51.6 82.8 6.6 6.6 7.7 8.9 7.7 9.1 8.4 7.3 7.9 -5.3 5.0 -4.0 6.6 7.5
Weight 4.5 21.9 38.4 -3.6 -4.8 -5.5 -4.9 -6.2 -5.3 -4.5 -4.7 -3.8 1.1 -3.9 3.2 -6.1 -5.5
Impedance of arm (right) 10.8 50.3 72.5 4.9 7.0 8.2 8.4 8.1 8.5 8.3 7.8 7.7 -4.3 4.2 -5.1 6.9 7.5
Arm fat percentage (right) 5.6 22.1 34.7 -3.5 -5.6 -5.1 -5.1 -5.9 -5.2 -4.8 -5.6 -3.8 2.2 -3.8 3.0 -5.2 -5.2
Trunk fat-free mass 2.5 14.1 32.5 -3.3 -2.7 -4.7 -4.1 -5.3 -4.5 -3.4 -2.7 -2.7 -0.1 -3.1 1.8 -5.7 -4.7
Hip circumference 4.4 18.9 28.8 -3.5 -4.9 -4.7 -4.3 -5.4 -4.5 -4.7 -4.4 -4.3 2.0 -4.4 2.4 -4.9 -5.1
Time employed in main current job 4.3 5.0 8.7 2.1 2.6 2.6 2.5 2.5 2.5 2.0 2.9 1.6 -0.3 2.2 -1.3 2.2 2.5
Alcohol intake versus 10 years previously 0.4 0.7 1.5 0.8 1.1 0.2 1.0 0.3 1.2 -0.3 0.4 -0.5 1.2 1.0 -0.6 1.0 0.7
Father’s age at death 7.4 9.9 21.7 1.5 4.2 3.9 3.6 3.4 3.3 4.7 3.8 3.8 -1.4 1.7 -0.6 1.9 2.8
Worrier / anxious feelings 33.1 62.6 88.5 7.3 7.6 8.9 9.2 8.3 9.4 9.0 9.0 9.1 -4.3 6.3 -3.7 7.0 8.9
Frequency of tiredness / lethargy in last 2 weeks 2.8 4.5 9.2 3.0 0.5 2.4 2.4 2.3 2.3 2.1 1.8 2.8 -1.8 2.0 -0.8 1.1 2.6
Falls in the last year 0.2 0.3 1.3 0.6 -0.7 -0.7 0.1 0.0 0.2 -0.7 -0.8 -1.2 -0.1 -0.1 -0.3 0.5 -0.1
Hair/balding pattern: Pattern 3 1.4 2.0 11.9 0.1 0.6 1.6 1.1 1.6 1.0 1.0 0.9 0.0 -1.3 -1.0 -3.4 1.9 0.6
Number of live births 0.5 0.6 2.1 1.2 -0.7 -0.4 0.4 0.4 0.8 0.2 -0.9 0.5 0.0 1.5 1.0 0.9 0.8
Forced expiratory volume in 1-second (FEV1) 4.6 15.6 30.7 3.4 5.5 3.5 4.7 2.9 4.6 4.7 5.3 3.8 -5.3 2.2 -1.7 1.0 3.3
Pulse rate 0.6 0.9 2.8 -0.3 0.1 0.7 1.7 0.9 1.5 1.3 1.0 0.9 -0.9 -0.1 -0.8 1.2 0.5
Happiness 0.2 0.3 0.9 0.7 -1.0 0.0 -0.1 0.1 0.1 0.7 -0.6 -0.2 -0.7 0.8 -0.2 0.3 0.2
Noisy workplace 2.6 3.3 8.5 2.1 1.4 1.6 1.3 2.2 1.5 1.3 0.8 1.5 0.4 2.9 -0.3 2.9 2.5
Qualifications: A levels/AS levels or equivalent 1.2 2.6 7.1 -1.1 1.8 1.4 2.4 1.2 1.7 2.2 2.7 2.0 -1.3 -0.4 -0.9 1.0 0.5
Serious illness, injury or assault of a close relative in last 2 years 3.3 3.7 7.5 1.9 1.6 2.2 2.2 2.2 1.9 2.6 2.7 2.3 -1.5 1.5 0.0 1.1 1.7
Mouth/teeth dental problems: Dentures 7.2 12.2 22.4 -1.7 -4.7 -3.7 -3.6 -3.7 -3.8 -4.2 -4.7 -4.4 2.6 -1.4 2.3 -2.7 -3.2
Asthma 2.1 4.1 8.3 -1.0 -1.9 -2.1 -2.8 -2.1 -2.5 -2.4 -2.0 -0.4 2.9 0.6 2.7 -1.7 -1.2
Medication: Ibuprofen (e.g. Nurofen) 1.3 1.6 3.3 1.3 1.2 1.1 1.8 1.5 1.8 1.4 1.3 1.1 -0.9 0.8 -0.1 1.1 1.4
Medication: Cholesterol lowering 1.0 1.6 3.3 -0.6 -1.4 -0.6 -1.6 -1.7 -1.6 -0.9 -1.3 -1.4 0.7 -0.9 0.5 -1.5 -1.8
Depression (self-reported) 2.9 3.4 6.2 2.1 1.1 2.4 1.9 2.0 2.2 2.0 1.4 1.7 -1.3 1.8 -0.3 2.0 2.5
Medication: Lansoprazole 0.7 0.8 3.0 0.7 -0.3 0.7 0.2 0.7 -0.3 -0.2 0.8 1.7 0.7 1.4 -0.1 1.4 1.1
Prospective memory result 0.2 0.3 1.5 -0.5 0.1 0.2 0.6 -0.2 0.2 0.1 -0.4 -0.5 1.2 -0.4 -0.7 0.3 -0.3
Lung cancer (father) 0.4 0.5 1.2 0.3 -1.1 -0.4 -0.7 -0.7 -0.7 -0.6 -1.0 -0.4 0.4 -0.7 -0.7 -0.8 -0.9
Illnesses of mother 0.4 0.5 1.4 -0.5 -0.2 0.7 0.6 0.6 0.7 0.2 0.3 -0.7 0.4 -1.0 -1.1 1.2 0.4
Forced expiratory volume in 1-second (FEV1), Best measure 5.0 16.0 30.7 3.7 5.5 3.7 4.6 3.3 4.8 4.7 5.3 3.5 -4.5 2.7 -1.7 1.7 4.0
Pulse wave Arterial Stiffness index 1.3 1.5 3.6 -0.5 -1.3 -1.8 -1.6 -1.4 -1.6 -1.9 -1.3 -0.6 0.7 -0.3 0.7 -1.2 -1.1
Impedance of arm (left) 10.0 46.5 67.9 4.8 6.2 8.2 8.1 8.2 8.1 7.8 7.5 7.4 -3.6 4.1 -4.6 6.8 7.4
Arm fat mass (right) 7.0 28.6 44.2 -4.2 -6.1 -6.0 -5.8 -6.6 -5.9 -5.5 -6.0 -4.6 2.4 -4.5 3.3 -5.9 -6.1
Trunk predicted mass 2.5 14.1 33.0 -3.2 -2.7 -4.6 -4.1 -5.3 -4.5 -3.4 -2.7 -2.7 -0.1 -3.0 1.8 -5.7 -4.7
Standing height 1.5 15.3 34.0 2.0 4.8 3.6 4.8 3.1 4.2 5.2 5.8 4.3 -4.8 1.7 -2.6 1.4 3.1
Length of working week for main job 1.8 2.0 5.8 0.8 -2.4 -1.5 -1.0 -1.2 -1.0 -1.3 -2.1 -2.0 -0.0 0.6 1.2 -1.8 -0.1
Exposure to tobacco smoke at home 0.4 0.5 2.0 -0.7 -0.2 -0.6 0.2 -0.4 -0.1 -0.8 -0.8 -1.1 0.1 -1.4 -0.9 0.1 -0.8
Breastfed as a baby 2.5 3.1 8.4 0.8 1.7 2.9 1.2 2.4 1.7 1.8 2.0 1.9 0.3 1.5 -0.7 1.9 2.0
Tense / ‘highly strung’ 13.4 22.3 35.5 5.3 4.7 4.8 5.3 4.7 5.5 6.0 4.1 5.3 -4.5 3.8 -2.7 3.0 5.3
Seen doctor (GP) for nerves, anxiety, tension or depression 3.6 5.5 9.7 2.8 1.6 2.5 2.1 2.3 2.5 2.6 2.0 3.1 -2.2 2.7 -0.4 1.4 3.1
Hair/balding pattern: Pattern 4 0.2 0.5 2.6 -0.5 0.3 0.4 0.6 0.1 -0.1 0.1 -0.2 -0.1 -1.6 -1.3 -0.9 -0.7 -0.3
Birth weight of first child 1.0 1.8 3.8 0.1 1.9 0.4 1.8 1.0 1.6 1.3 2.0 1.7 -0.5 -1.1 -1.5 1.5 0.7
Peak expiratory flow (PEF) 11.4 26.5 45.4 5.7 6.7 5.3 5.7 4.9 5.8 5.9 5.9 4.9 -3.9 4.8 -1.4 2.9 5.7
Pulse wave reflection index 1.2 1.5 5.6 0.7 -0.8 -1.3 -2.4 -0.9 -1.9 -1.1 -1.2 -0.5 0.4 0.9 1.7 -1.2 -0.1
Ever highly irritable/argumentative for 2 days 1.7 2.0 9.5 1.4 -0.5 0.5 1.2 0.9 0.9 1.8 1.0 3.1 -1.6 2.0 1.1 0.4 1.1
Loud music exposure frequency 0.7 0.7 5.5 -1.2 -0.9 -0.1 -0.5 -0.2 -0.6 -1.0 0.3 0.7 2.3 -0.0 0.6 0.4 -0.3
Qualifications: O levels/GCSEs or equivalent 4.7 7.4 18.8 1.4 3.4 2.9 3.6 2.7 3.1 3.0 4.3 2.5 -1.3 1.5 -1.4 2.2 2.7
Mouth/teeth dental problems: Bleeding gums 3.5 4.6 9.8 -0.9 -2.5 -2.8 -2.4 -2.2 -2.3 -1.6 -3.1 -2.3 -0.4 -0.3 2.4 -2.7 -1.5
Blood clot in the leg (DVT) 4.1 5.4 9.1 -2.8 -2.4 -2.5 -2.7 -2.9 -3.0 -2.4 -2.5 -1.4 -1.7 -1.8 0.5 -2.1 -2.6
Medication: Paracetamol 2.4 4.0 19.2 1.7 1.6 1.7 2.0 1.8 2.2 2.2 0.9 2.2 -4.4 0.5 -1.3 1.1 1.5
Headache pain in last month 5.7 9.8 15.7 2.1 3.0 3.3 3.7 2.8 4.0 3.5 2.8 3.9 -3.8 1.5 -2.5 2.2 3.6
Medication for cholesterol, blood pressure or diabetes 4.4 7.3 11.5 2.3 3.3 2.4 2.9 3.3 3.1 3.1 2.7 2.8 -1.5 2.4 -0.3 2.5 3.4
Glaucoma (self-reported) 0.1 0.2 0.5 -0.3 -0.7 -0.2 -0.2 -0.4 -0.4 -0.7 -0.6 -0.4 -0.1 -0.2 0.3 -0.4 -0.4
Gout (self-reported) 0.2 0.2 1.0 0.2 -0.7 0.4 -1.0 -0.5 -0.5 -0.4 -0.2 -0.7 0.3 0.3 -0.2 -0.5 -0.1
Hypothyroidism/myxoedema (self-reported) 13.1 25.6 38.6 4.0 5.7 6.2 6.2 5.6 5.8 5.8 6.0 6.1 -2.5 2.6 -2.6 3.9 5.2
Medication: Amlodipine 2.5 3.5 5.9 -0.8 -1.6 -2.3 -2.4 -2.3 -2.1 -2.4 -2.3 -2.3 -0.3 -1.0 0.1 -1.5 -2.2
Medication: Ventolin 100micrograms inhaler 1.3 1.7 4.3 -0.2 -1.4 -1.1 -1.5 -1.2 -1.4 -0.9 -1.4 -1.0 2.1 0.9 2.1 -1.3 -0.2
Birth weight 0.3 0.6 1.4 -1.1 -0.2 -1.1 -0.3 -0.8 -0.3 -0.5 -0.6 -1.0 0.5 -1.2 -0.8 0.4 -0.9
Chronic bronchitis/emphysema (mother) 0.4 0.5 2.0 0.2 0.4 -0.3 -0.4 -0.4 -0.6 0.3 0.2 1.3 -0.6 1.3 -0.0 -1.4 -0.2
High blood pressure (siblings) 2.9 4.1 7.3 -2.4 -1.6 -2.1 -1.9 -2.6 -1.7 -2.5 -2.7 -1.9 0.1 -2.0 -1.5 -1.6 -2.4
Forced vital capacity (FVC), Best measure 1.4 5.1 13.4 1.9 3.7 1.8 2.4 1.6 2.5 2.5 3.6 1.9 -2.6 1.4 -0.9 0.3 2.1
Body fat percentage 2.6 10.1 19.2 -1.9 -4.4 -3.2 -3.3 -3.9 -3.3 -3.2 -3.9 -2.7 2.1 -2.7 2.4 -3.2 -3.4
Leg fat percentage (right) 3.7 13.3 24.0 -1.8 -4.7 -3.7 -4.0 -4.2 -4.0 -4.1 -4.9 -3.1 2.8 -2.8 2.4 -3.4 -3.8
Arm fat-free mass (right) 3.6 18.4 32.0 -3.4 -3.6 -5.1 -4.8 -5.7 -5.0 -4.4 -3.5 -4.0 1.5 -3.3 3.1 -5.6 -5.0
Exposure to tobacco smoke outside home 0.3 0.4 2.0 0.3 -0.2 0.2 0.7 0.1 0.4 0.6 0.3 -0.2 -1.4 -1.1 -0.9 -0.0 -0.1
Comparative body size at age 10 11.9 32.8 48.9 -5.6 -5.2 -6.7 -6.3 -7.0 -6.5 -6.3 -6.3 -5.8 2.1 -5.3 1.3 -5.6 -6.7
Number of full brothers 4.3 5.4 7.8 -1.8 -1.8 -2.7 -2.8 -2.8 -2.3 -1.9 -2.5 -1.8 2.2 -1.1 2.8 -2.8 -2.5
Worry too long after embarrassment 12.4 20.8 34.4 3.7 4.4 5.4 5.9 4.8 5.7 5.8 4.6 5.5 -2.6 2.2 -2.9 3.6 4.7
Seen a psychiatrist for nerves, anxiety, tension or depression 0.8 1.0 3.6 0.7 -0.5 1.9 0.3 1.4 0.6 0.8 0.9 1.3 0.6 0.2 -0.6 1.4 1.3
Wheeze or whistling in the chest in last year 3.7 6.6 13.1 -1.2 -3.6 -2.6 -3.6 -2.6 -3.3 -3.6 -3.3 -1.7 1.8 0.8 1.9 -2.0 -1.5
Number of children fathered 1.1 1.2 6.3 0.1 -2.5 -1.0 -1.3 -1.1 -1.3 -1.4 -1.3 -0.4 0.2 0.8 0.0 -0.8 -0.3
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.2 1.0 -0.4 0.1 0.5 1.0 -0.1 0.9 0.2 -0.3 0.1 0.7 -0.2 -0.2 0.5 0.2
Age at first live birth 5.3 9.5 15.6 1.7 3.9 3.2 3.4 3.5 3.5 3.9 3.7 3.2 -1.9 1.2 -2.7 3.1 2.8
Pulse wave peak to peak time 1.9 2.2 5.1 0.6 1.6 1.9 2.0 1.7 1.9 2.3 1.7 0.8 -0.9 0.4 -0.8 1.4 1.3
Health satisfaction 4.9 6.3 15.0 -1.8 -3.9 -2.7 -2.5 -2.9 -2.6 -1.9 -3.4 -1.5 -0.3 -2.1 1.9 -3.0 -2.5
Shortness of breath walking on level ground 1.2 1.4 5.2 -0.0 -2.3 -1.2 -1.3 -1.0 -1.2 -1.3 -2.1 -0.4 -0.6 0.3 1.1 -0.6 -0.1
Qualifications: College or University degree 0.4 1.2 3.8 -0.9 1.7 0.6 0.3 0.7 0.1 0.8 1.8 1.6 -1.9 -1.0 -0.8 -0.1 0.1
Eye problems/disorders: None of the above 1.0 1.1 3.8 0.3 1.5 0.8 0.3 0.2 0.9 1.5 1.3 1.4 -0.4 1.1 2.0 -0.6 0.7
Mouth/teeth dental problems: Loose teeth 2.9 3.5 12.5 -1.0 -2.3 -2.3 -2.6 -1.5 -2.1 -1.7 -3.5 -2.3 0.7 -0.7 0.1 -0.3 -1.6
Emphysema/chronic bronchitis 7.1 8.0 16.3 -1.6 -3.8 -3.1 -3.3 -2.7 -3.1 -4.0 -3.3 -3.1 3.4 -1.0 1.3 -1.4 -2.2
Medication for pain relief, constipation, heartburn 0.6 1.0 4.9 -0.8 0.8 -0.8 -1.4 -0.7 -1.1 -0.9 0.2 -0.6 2.2 0.4 1.2 -0.9 -0.2
Neck or shoulder pain in last month 0.2 0.3 1.1 0.5 -0.6 0.8 1.0 0.6 0.6 0.0 0.1 -0.1 0.0 0.8 0.3 0.5 0.5
Medication: Blood pressure 8.2 14.4 22.6 -2.9 -4.8 -4.0 -4.2 -4.7 -4.5 -4.1 -4.1 -3.5 1.5 -2.5 1.6 -4.3 -4.3
Angina (self-reported) 1.0 1.3 4.4 0.2 -2.0 -0.5 -0.9 -0.9 -0.9 -0.6 -1.6 -2.1 -0.8 1.1 0.8 -1.3 -0.5
Migraine (self-reported) 1.3 1.6 3.0 0.8 1.6 1.6 1.2 1.4 1.6 1.3 0.8 0.3 -0.9 1.1 -1.2 1.7 1.5
Medication: Ibuprofen 1.2 1.4 2.8 1.3 0.8 1.1 1.5 1.4 1.7 1.5 1.1 1.0 -1.1 1.0 0.2 0.9 1.4
Medication: Allopurinol 0.5 0.6 2.4 0.3 -1.1 0.1 -1.5 -0.9 -1.2 -0.4 -0.8 -0.5 0.0 0.4 0.3 -1.1 -0.3
Medication: Omeprazole 1.0 1.2 5.7 -0.0 -2.4 -0.4 -0.4 -0.5 -0.9 -0.3 -1.4 -1.6 -1.7 -0.6 -1.0 -1.0 -0.6
Medication: Seretide 50 evohaler 0.8 0.9 4.9 0.4 -0.5 -0.0 -1.4 -0.1 -1.0 -1.1 -0.6 0.0 2.2 0.8 1.3 -0.2 0.4
Mean time to correctly identify matches 0.1 0.3 1.1 0.4 -0.9 0.2 -0.1 0.2 -0.1 0.2 -1.1 -0.6 -0.5 -0.4 0.6 -0.1 -0.5
Heart disease (mother) 0.3 0.4 1.5 0.5 -0.1 0.8 0.5 0.3 0.4 0.2 0.8 1.2 -0.5 0.8 0.7 0.5 0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 4.3 5.1 8.8 2.3 2.8 2.9 1.9 2.5 2.3 3.0 2.4 2.7 -0.9 1.7 -0.8 1.9 2.3
Whole body fat mass 4.0 16.9 27.1 -2.9 -4.9 -4.4 -4.4 -5.2 -4.5 -4.0 -4.5 -3.5 2.0 -3.5 2.9 -4.7 -4.6
Leg fat mass (right) 5.8 22.5 33.4 -3.1 -5.5 -5.2 -5.2 -5.8 -5.4 -5.0 -5.6 -4.2 2.9 -3.7 3.3 -4.9 -5.1
Arm predicted mass (right) 3.9 20.0 37.1 -3.5 -3.8 -5.4 -5.1 -5.9 -5.3 -4.5 -3.7 -3.9 1.3 -3.3 3.1 -6.1 -5.2
Pulse rate, automated reading 0.3 0.8 2.5 -0.2 -1.3 -1.6 -0.2 -1.4 -0.5 -1.2 -1.2 -0.9 0.9 -0.1 0.3 -0.3 -0.7
Alcohol intake frequency. 0.2 0.5 1.5 1.1 1.1 -0.1 0.7 0.2 0.8 0.2 1.2 0.6 -0.7 0.8 -0.1 -0.1 0.4
Comparative height size at age 10 0.4 2.0 5.5 -1.7 -0.7 -1.3 -0.9 -2.0 -1.3 -0.6 -1.1 -2.0 -0.7 -1.2 -0.4 -2.3 -1.7
Number of full sisters 1.4 1.7 7.5 0.1 -1.7 -1.4 -1.0 -1.4 -0.9 -1.6 -2.7 -1.8 -0.3 0.6 0.5 -0.7 -0.5
Suffer from ‘nerves’ 10.1 15.9 23.5 4.2 3.5 4.6 4.6 4.5 4.8 4.9 3.6 4.4 -3.1 3.4 -1.7 2.8 4.4
Overall health rating 4.6 9.8 28.5 -1.6 -5.3 -3.2 -3.4 -3.1 -3.6 -3.1 -4.4 -3.0 0.7 -1.5 1.4 -3.5 -2.6
Chest pain or discomfort 0.3 0.4 0.9 0.9 -0.3 0.4 0.6 0.6 0.2 0.2 -0.1 0.9 -0.2 1.0 0.2 0.8 0.9
Had major operations 0.5 0.6 3.2 1.8 0.2 0.8 0.6 0.4 0.3 0.4 0.4 0.9 -0.4 1.6 0.2 -0.3 0.7
Age at last live birth 6.4 9.4 14.5 2.8 3.3 3.3 3.2 3.5 3.3 3.5 3.8 3.4 -2.0 2.2 -2.5 2.3 2.9
Family relationship satisfaction 0.4 0.5 2.4 0.1 -1.0 0.3 0.1 0.5 0.2 1.2 -0.0 0.9 -1.5 0.2 -0.0 0.8 0.6
Leg pain on walking 2.1 2.7 8.6 0.1 -1.6 -2.3 -1.6 -2.1 -1.6 -0.9 -1.7 -1.4 -1.0 0.2 1.9 -2.9 -1.2
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.3 0.9 -0.6 0.4 -0.5 0.4 -0.2 0.4 0.3 0.2 0.2 -0.9 -0.4 -1.0 0.5 -0.3
Commuting to job workplace: Car/motor vehicle 0.5 0.6 2.0 0.0 -0.1 -0.6 -0.6 -0.9 -0.8 -0.3 -1.4 -0.2 -0.2 -0.9 -1.2 -1.0 -0.7
Illness, injury, bereavement, stress in last 2 years 1.0 1.2 3.2 -1.0 0.1 -1.7 -1.8 -0.9 -1.5 -1.3 -1.2 0.0 1.1 -0.1 1.1 -0.5 -0.8
Medication: Aspirin 2.4 3.2 9.9 -1.0 -3.2 -1.5 -2.2 -1.5 -2.1 -2.3 -2.7 -1.9 1.2 -0.6 0.5 -0.0 -1.3
Supplements: Vitamin C 3.8 4.5 12.6 -1.5 -3.5 -1.8 -2.5 -1.8 -2.5 -2.4 -3.1 -2.9 1.0 -0.5 0.7 -1.4 -1.4
Knee pain experienced in last month 1.4 2.1 5.4 -0.7 -2.3 -1.8 -1.1 -1.7 -1.3 -0.8 -1.7 -1.7 -0.7 -0.6 1.1 -1.9 -1.6
Hypertension (Self-reported) 12.2 33.8 49.7 -3.8 -7.0 -6.7 -7.0 -6.8 -6.7 -6.7 -7.0 -5.5 3.5 -2.9 3.7 -5.5 -5.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.5 3.8 0.3 0.3 0.4 0.4 0.6 0.6 -0.6 -0.2 -0.2 1.0 -0.7 -2.0 0.8 0.3
Illnesses of father: Heart disease 0.8 1.1 7.6 1.4 -1.1 0.3 0.4 -0.1 0.3 -0.2 0.1 0.4 -0.2 1.7 2.8 -0.5 0.6
Illnesses of siblings: Diabetes 1.1 1.3 5.4 -1.3 -1.1 -0.9 -1.4 -0.8 -1.4 -2.3 -1.4 -1.0 0.3 -0.7 -0.5 0.2 -1.1
Smoking status: Previous 0.6 0.9 4.8 0.3 -2.2 -0.2 -0.8 -0.9 -0.7 -0.9 -1.2 -0.8 1.1 -0.0 1.4 -0.4 0.2
Forced expiratory volume in 1-second (FEV1), predicted 2.1 4.3 10.4 1.6 1.7 2.3 2.3 2.1 2.2 2.7 3.2 2.0 -1.6 1.5 -1.7 1.2 2.1
Whole body fat-free mass 3.5 20.0 40.3 -3.8 -3.7 -5.5 -4.9 -6.1 -5.3 -4.2 -3.6 -3.6 0.4 -3.5 2.8 -6.3 -5.3
Leg fat-free mass (right) 4.7 25.3 43.8 -4.5 -4.5 -6.1 -5.4 -6.6 -5.8 -4.8 -4.4 -4.5 1.0 -4.1 3.3 -6.6 -5.8
Arm fat percentage (left) 5.8 23.1 33.7 -3.7 -5.8 -5.1 -5.2 -5.8 -5.3 -5.0 -5.7 -3.8 2.6 -3.9 3.4 -5.2 -5.4
Average weekly red wine intake 2.3 3.4 10.1 -2.2 -2.8 -1.5 -2.0 -1.4 -1.9 -1.3 -1.9 -0.5 3.2 -1.0 2.0 -0.4 -1.5
Handedness (chirality/laterality): Left-handed 0.4 0.4 1.0 -0.8 -0.6 0.1 -0.9 -0.2 -0.3 -0.9 -0.7 -0.7 1.0 -0.4 1.0 -0.2 -0.0
Mood swings 9.6 17.4 27.2 4.6 3.3 4.1 5.0 4.5 5.2 5.0 3.7 3.7 -4.8 3.9 -0.6 3.1 4.6
Loneliness, isolation 0.8 1.1 3.1 0.8 0.6 0.6 1.7 0.9 1.8 1.5 0.9 0.5 -0.4 0.6 -0.0 1.4 1.0
Long-standing illness, disability or infirmity 0.6 0.9 4.8 0.5 -2.2 -0.6 -0.3 -0.9 -0.5 -0.5 -1.2 -0.6 -0.8 -0.7 0.3 -1.3 -0.7
Ever had bowel cancer screening 1.7 2.0 3.3 1.4 1.6 1.8 1.6 1.6 1.3 1.4 1.2 1.8 -1.4 1.0 -1.0 0.7 1.5
Diabetes diagnosed by doctor 2.1 3.5 7.4 -1.6 -1.4 -2.4 -1.7 -2.2 -2.0 -2.4 -2.1 -1.4 1.1 -1.9 -0.9 -1.2 -2.7
Ever had stillbirth, spontaneous miscarriage or termination 5.3 5.7 12.6 -2.2 -2.3 -2.5 -2.8 -2.9 -2.8 -2.5 -3.2 -0.1 0.7 -1.5 0.3 -3.5 -2.7
Friendships satisfaction 0.3 0.4 1.6 0.7 -0.5 -0.2 0.4 0.2 0.6 0.2 -0.5 0.4 -1.3 0.1 -0.7 0.9 0.6
Qualifications: nursing, teaching 0.7 1.0 4.3 0.9 1.3 1.0 0.9 0.9 0.7 0.7 1.1 1.0 -0.5 2.1 0.3 0.5 1.1
Commuting to job workplace: Walk 0.6 0.6 3.4 0.8 0.5 0.9 -0.3 0.5 0.4 0.9 0.3 -0.2 -1.8 0.4 1.3 -0.3 0.6
Eye problems/disorders: Cataract 0.5 0.6 2.5 -0.1 -0.4 -0.4 0.2 -0.1 -0.1 -1.3 0.2 -0.7 1.1 -0.5 -1.6 1.3 -0.3
Mouth/teeth dental problems: Mouth ulcers 1.5 2.4 9.0 0.4 1.1 1.7 1.8 1.9 2.1 0.9 0.5 1.1 -0.5 -0.2 -1.9 3.0 1.7
Medication for cholesterol 5.5 8.3 14.2 2.5 3.2 3.0 3.3 3.4 3.2 3.5 3.8 3.0 -1.1 2.6 0.1 2.2 3.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.3 1.1 1.1 -0.4 0.4 0.0 -0.1 0.1 0.2 -0.5 -0.6 -0.8 0.7 0.7 -0.7 0.1
Back pain experienced in last month 0.5 0.7 3.9 -0.3 -0.9 -0.7 0.5 -1.1 -0.1 -0.9 -0.5 0.3 -0.4 -0.8 -2.0 -1.1 -0.8
Mineral and other dietary supplements 5.0 6.7 13.5 1.9 3.5 2.2 3.3 2.3 3.1 3.2 3.7 3.0 -2.1 1.4 -1.4 1.6 2.0
Breast cancer (self-reported) 0.8 1.0 4.2 -1.2 -1.2 0.9 -0.2 0.1 -0.0 -0.5 -0.7 -1.0 1.4 -2.1 -1.4 0.0 -0.3
Asthma (self-reported) 2.6 5.2 12.2 -1.2 -2.1 -2.3 -3.1 -2.4 -2.8 -2.9 -2.4 -0.9 3.5 0.3 2.5 -1.7 -1.5
Osteoporosis (self-reported) 5.4 6.7 11.0 2.1 2.8 2.8 3.2 2.9 2.8 2.7 3.0 3.3 -1.3 2.1 -0.7 2.1 2.7
Osteoarthritis (self-reported) 2.2 2.8 6.7 -0.7 -0.6 -2.4 -1.4 -2.6 -1.5 -2.5 -1.5 -1.6 0.2 -0.3 1.4 -2.2 -2.2
Medication: Aspirin 2.0 2.6 7.8 -0.1 -2.8 -1.5 -2.0 -1.3 -1.8 -2.1 -2.5 -2.1 1.0 -0.4 0.7 -0.1 -1.2
Medication: Gliclazide 1.2 1.3 2.8 -1.3 -1.0 -1.3 -1.0 -1.5 -1.0 -1.7 -1.1 -0.1 1.1 -1.1 -0.4 -0.8 -1.7
Illnesses of father: None of the above (group 1) 2.1 2.6 11.5 -0.5 2.1 1.0 1.8 1.5 1.7 1.2 1.8 0.1 -0.4 -1.2 -3.4 2.3 0.5
Smoking status: Current 6.2 9.9 16.0 -1.4 -3.4 -3.9 -4.0 -3.6 -3.7 -3.6 -3.6 -3.6 1.5 -0.8 1.4 -3.5 -3.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 4.3 9.0 26.5 2.4 5.2 3.0 3.3 2.3 3.4 3.4 4.4 2.6 -2.1 0.9 -2.2 1.5 2.4
Whole body water mass 3.6 20.3 40.6 -3.9 -3.7 -5.5 -4.9 -6.1 -5.3 -4.2 -3.6 -3.7 0.5 -3.5 2.8 -6.4 -5.4
Leg predicted mass (right) 4.7 25.0 44.0 -4.5 -4.5 -6.1 -5.4 -6.6 -5.8 -4.8 -4.4 -4.4 0.9 -4.0 3.3 -6.6 -5.8
Arm fat mass (left) 6.7 27.7 41.8 -4.3 -6.0 -5.8 -5.7 -6.5 -5.9 -5.4 -5.8 -4.3 2.5 -4.5 3.5 -5.9 -6.0
Number of self-reported non-cancer illnesses 0.2 0.3 1.1 -0.3 -1.0 0.0 -0.2 -0.6 0.1 -0.7 -1.0 -0.0 0.6 -0.5 0.3 -0.2 -0.5
Average weekly champagne plus white wine intake 2.2 3.0 8.7 -2.9 -0.1 -2.2 -1.3 -2.4 -1.3 -0.7 -1.1 -0.9 0.1 -2.3 0.9 -2.0 -2.5
Miserableness 17.5 30.3 47.1 6.0 4.3 5.9 6.3 6.1 6.9 6.0 5.5 5.2 -5.1 4.9 -2.3 5.1 6.2
Guilty feelings 8.9 13.4 19.2 3.1 3.3 4.3 4.2 4.2 4.2 4.4 3.5 4.4 -2.0 3.5 -1.5 2.9 4.4
Wears glasses or contact lenses 0.2 0.3 1.6 0.2 0.7 0.8 0.4 0.3 -0.1 -0.4 1.3 0.1 -0.3 0.1 0.5 0.0 0.2
Ever taken oral contraceptive pill 0.5 0.6 2.4 -1.6 -0.6 -0.9 0.1 -0.9 -0.2 0.1 -0.5 0.5 -0.8 -0.8 -1.1 -0.4 -0.8
Hearing aid user 0.2 0.2 1.2 0.0 -1.1 -0.7 -0.3 -0.4 -0.3 -0.0 -0.5 0.6 0.1 0.1 0.2 0.2 -0.5
Mother’s age at death 2.5 3.1 10.8 1.3 3.3 1.8 1.5 1.6 2.0 2.7 2.1 1.6 -1.1 0.3 -0.6 1.1 1.2
Financial situation satisfaction 0.6 0.7 2.0 -0.8 -1.2 -1.4 -0.7 -1.0 -0.6 -0.2 -1.0 0.0 0.8 0.3 1.3 -0.5 -0.7
Tinnitus: Yes, now most or all of the time 0.8 0.9 2.1 1.2 0.7 0.7 1.0 0.5 0.8 1.4 1.3 0.7 -1.4 1.0 -0.5 0.4 0.9
Commuting to job workplace: Public transport 2.2 2.6 6.4 0.5 1.7 1.5 1.6 1.3 1.6 2.4 2.5 2.5 -1.5 1.4 -0.0 0.3 1.3
Eye problems/disorders: Glaucoma 0.6 0.7 2.5 -0.6 -1.6 -0.5 -1.0 -0.4 -1.1 -1.4 -0.9 -1.2 -0.1 -0.2 -0.2 -0.5 -0.4
Medication: Blood pressure 10.6 20.1 36.6 -3.7 -4.7 -5.5 -5.4 -5.1 -4.9 -5.0 -6.0 -4.5 2.1 -3.2 1.1 -3.4 -5.2
Pain type(s) experienced in last month: Hip pain 3.0 3.8 10.3 -0.7 -2.1 -2.1 -1.9 -2.6 -2.2 -2.0 -2.3 -1.5 -1.1 -0.5 1.6 -3.2 -1.8
Supplements: Fish oil (including cod liver oil) 6.7 8.8 20.2 -2.0 -3.3 -3.1 -3.2 -3.2 -3.3 -3.5 -4.5 -3.4 2.3 -2.0 1.0 -2.3 -2.7
High cholesterol (Self-reported) 2.1 3.8 8.4 -1.0 -2.9 -1.1 -2.1 -2.1 -1.9 -1.7 -2.7 -2.6 1.1 -1.5 1.0 -1.8 -2.1
Medication: Bendroflumethiazide 13.2 20.1 33.6 -2.5 -4.8 -5.3 -5.5 -5.2 -5.1 -4.8 -5.7 -5.8 0.8 -2.2 1.7 -5.0 -4.3
Medication: Paracetamol 1.9 2.9 14.4 1.7 1.3 1.5 1.4 1.6 1.7 1.6 0.5 2.2 -3.8 0.3 -1.3 1.1 1.2
Medication: Lisinopril 3.7 4.8 9.1 -1.8 -2.2 -2.6 -2.4 -2.6 -2.7 -2.5 -3.0 -2.2 1.2 -0.9 1.8 -1.3 -2.3
Medication: Atorvastatin 0.5 0.6 2.7 0.7 -0.8 -0.3 -1.0 -0.6 -0.5 -0.4 -0.8 -1.3 -0.0 0.9 1.6 0.2 -0.3
Illnesses of father: High blood pressure 2.8 3.4 10.5 -1.4 -1.3 -1.7 -2.1 -2.6 -2.0 -1.4 -1.7 -0.7 0.3 -1.8 1.3 -3.2 -2.2
Alcohol drinker status: Never 1.2 1.4 3.3 0.3 0.7 1.8 1.4 1.5 1.3 1.7 1.4 1.3 -0.6 -0.1 -1.0 1.3 0.9
Ever smoked 0.4 0.7 1.5 0.6 -1.2 -0.7 -1.0 -1.1 -0.8 -0.9 -0.9 -0.7 0.5 0.6 0.9 -1.1 0.1
Basal metabolic rate 3.9 21.8 42.5 -3.9 -4.2 -5.7 -5.0 -6.3 -5.4 -4.4 -4.0 -3.8 0.6 -3.8 3.0 -6.5 -5.5
Leg fat percentage (left) 3.8 13.7 21.8 -1.9 -4.7 -3.8 -4.0 -4.3 -4.0 -4.3 -4.7 -3.4 3.2 -3.0 2.3 -3.2 -3.8
Arm fat-free mass (left) 3.8 19.1 35.8 -3.3 -3.8 -5.3 -4.9 -6.0 -5.1 -4.3 -3.8 -3.9 0.8 -3.1 2.9 -6.0 -5.0
Number of operations (self-reported) 2.1 3.1 7.4 0.2 -2.5 -1.2 -2.3 -1.8 -2.0 -1.8 -2.7 -1.7 1.2 0.2 1.6 -1.8 -1.4
Average weekly beer plus cider intake 13.1 19.0 28.8 5.4 4.0 4.5 4.4 5.1 4.8 4.4 4.9 3.6 -4.3 4.0 -1.4 3.5 5.2
Irritability 24.4 41.2 69.2 5.9 6.3 6.5 8.3 6.6 8.2 7.6 6.7 6.7 -5.5 4.9 -2.8 5.3 6.5
Risk taking 6.9 10.1 15.9 -2.9 -3.7 -3.6 -3.6 -4.0 -3.2 -3.6 -3.3 -3.6 0.8 -2.7 0.1 -3.5 -3.2
Ever had prostate specific antigen (PSA) test 0.7 0.8 3.5 -1.4 -0.3 0.0 0.1 -0.3 -0.1 -0.6 -0.6 0.7 -1.4 -1.5 -1.9 -0.0 -0.4
Fractured/broken bones in last 5 years 1.6 2.0 5.1 2.2 1.4 1.2 1.3 1.8 1.5 2.3 0.7 0.2 -1.5 1.6 0.4 0.1 1.4
Age started oral contraceptive pill 2.7 3.4 9.5 0.4 1.5 2.7 1.4 2.3 1.7 1.5 2.2 1.4 1.3 0.8 -2.1 3.1 1.4
Diastolic blood pressure, automated reading 12.8 39.5 60.2 -4.3 -7.4 -7.3 -7.1 -7.5 -7.8 -7.2 -7.3 -5.2 4.5 -3.3 4.0 -6.2 -6.4
Ever depressed for a whole week 2.3 2.8 5.3 2.3 0.5 1.5 2.1 1.3 1.9 2.2 0.8 2.3 -2.2 1.5 0.1 0.7 1.8
Unable to work because of sickness or disability 2.5 3.3 9.3 -1.0 -2.9 -1.6 -2.1 -1.8 -2.2 -1.8 -3.0 -1.6 0.6 -0.1 0.8 -1.8 -1.4
Commuting to job workplace: Cycle 0.4 0.5 1.5 0.0 0.7 -0.5 1.1 0.4 1.1 -0.0 1.0 0.8 0.5 -0.1 0.8 1.2 0.3
Myopia 1.2 1.8 6.9 0.7 2.6 0.9 1.2 0.7 1.4 1.5 2.3 2.3 -0.2 0.1 -0.6 0.4 0.2
Vascular/heart problems diagnosed by doctor 10.0 27.1 40.2 3.7 6.3 5.7 6.2 6.3 6.0 5.8 6.3 4.9 -2.5 2.8 -3.2 5.2 5.5
Cholesterol lowering medication 0.4 0.5 2.1 0.6 -1.4 -0.3 -0.2 -0.4 0.2 -0.9 -1.0 -0.8 1.1 -0.5 -0.3 0.5 -0.5
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 2.7 0.4 -1.6 0.0 0.4 -0.0 -0.1 0.2 -0.6 -0.8 -1.5 -0.4 -1.2 -0.3 -0.1
Pain experienced in last month 0.2 0.3 1.1 0.3 1.1 0.1 -0.8 0.3 -0.4 0.2 0.3 -0.3 1.0 0.5 0.9 0.5 -0.1
Supplements: Calcium 0.7 0.7 2.8 0.5 -0.7 1.1 0.9 1.1 0.7 0.2 0.1 0.3 1.1 1.0 -0.2 1.7 0.9
Basal cell carcinoma (self-reported) 0.2 0.2 1.1 0.2 -0.7 -0.0 -0.0 -0.3 -0.1 -0.1 -1.1 -0.2 -0.4 -0.5 0.3 -0.6 -0.4
Heart attack/myocardial infarction (self-reported) 0.2 0.2 1.5 1.0 -0.4 0.3 0.3 -0.1 -0.0 0.3 -0.3 0.4 -0.3 1.2 0.3 0.3 0.2
Deep venous thrombosis (DVT) (self-reported) 4.5 5.8 9.7 -2.9 -2.6 -2.6 -2.9 -3.0 -3.1 -2.7 -2.7 -1.6 -1.4 -1.7 0.4 -2.1 -2.7
Heart disease (siblings) 0.4 0.5 3.2 0.2 -0.5 -0.2 0.3 -0.1 0.4 0.2 -1.2 -0.6 -1.8 -0.4 -1.0 -0.4 -0.6
Alcohol drinker status: Previous 0.9 1.0 3.2 -0.8 -0.4 -0.7 -0.3 -1.1 -0.6 -0.9 0.9 -0.9 -0.4 -1.8 -1.1 -1.3 -1.5
Pack years of smoking 1.0 1.5 6.1 -0.3 -1.9 -1.5 -1.6 -1.0 -1.1 -1.2 -2.5 -1.3 0.9 -0.3 -0.3 -0.3 -0.7
Impedance of whole body 12.4 63.2 90.9 6.5 7.5 9.3 9.3 9.5 9.5 8.9 8.7 8.0 -3.5 5.3 -5.1 8.3 8.8
Leg fat mass (left) 5.6 21.9 33.0 -3.1 -5.4 -5.2 -5.2 -5.7 -5.3 -5.1 -5.3 -4.3 3.0 -3.7 3.3 -4.7 -5.0
Arm predicted mass (left) 4.0 20.5 38.4 -3.4 -3.9 -5.5 -5.1 -6.2 -5.3 -4.4 -4.0 -4.1 0.9 -3.1 3.2 -6.2 -5.2