Best TWAS P=1.26e-09 · Best GWAS P=1.32e-10 conditioned to 0.0317
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Muscle Skeletal | KCTD9 | 0.11 | 0.07 | lasso | 5 | 0.06 | 7.9e-07 | -5.5 | -6.0 | 1.9e-09 | 0.85 | 0.13 | 0.86 | FALSE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | KCTD9 | 0.03 | 0.01 | blup | 75 | 0.01 | 1.1e-02 | -6.3 | -6.1 | 1.3e-09 | 0.92 | 0.02 | 0.72 | TRUE |