Best TWAS P=6.77e-10 · Best GWAS P=1.27e-11 conditioned to 3.01e-10
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | YFS | Blood | R3HCC1 | 0.03 | 0.01 | lasso | 6 | 0.01 | 5.3e-04 | -5.9 | 5.7 | 1.6e-08 | 0.01 | 0.12 | 0.85 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | STC1 | 0.04 | 0.05 | enet | 7 | 0.06 | 8.9e-12 | -6.3 | 6.2 | 6.8e-10 | 0.03 | 0.01 | 0.99 | TRUE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | CHMP7 | 0.10 | 0.02 | lasso | 6 | 0.04 | 5.4e-05 | 2.8 | -5.9 | 3.9e-09 | -0.05 | 0.00 | 0.99 | TRUE |