[Hub]/) : Traits : Trunk fat-free mass : ← →

chr9:126,844,856-128,824,378

Best TWAS P=3.88e-12 · Best GWAS P=5.9e-12 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	PPP6C	0.06	0.10	lasso	3	0.07	3.2e-06	5.4	-5.4	8.0e-08	0.74	0.95	0.04	FALSE
2	GTEx	Artery Aorta	PRPS1P2	0.08	0.10	lasso	4	0.08	2.1e-05	-4.4	5.3	8.6e-08	-0.85	0.07	0.87	FALSE
3	GTEx	Artery Tibial	GAPVD1	0.11	0.16	enet	19	0.16	6.4e-13	-6.5	-6.9	4.3e-12	0.94	0.02	0.98	FALSE
4	GTEx	Artery Tibial	PRPS1P2	0.06	0.06	enet	6	0.05	9.2e-05	5.5	5.5	2.9e-08	-0.65	0.86	0.11	FALSE
5	GTEx	Brain Cerebellum	PRPS1P2	0.09	0.08	enet	16	0.04	2.8e-02	-6.7	6.3	3.2e-10	-0.84	0.05	0.78	FALSE
6	GTEx	Breast Mammary Tissue	PPP6C	0.11	0.08	enet	10	0.08	7.0e-05	5.5	-5.3	1.0e-07	0.66	0.45	0.38	FALSE
7	GTEx	Breast Mammary Tissue (Male)	PPP6C	0.12	0.03	enet	12	0.03	6.5e-02	5.5	-5.5	4.2e-08	0.64	0.07	0.10	FALSE
8	GTEx	Breast Mammary Tissue (Female)	PPP6C	0.14	0.04	lasso	4	0.04	3.1e-02	5.5	-5.9	3.1e-09	0.74	0.08	0.78	FALSE
9	GTEx	Cells EBV-transformed lymphocytes	GOLGA1	0.13	0.00	enet	8	0.06	3.8e-03	5.6	5.5	4.3e-08	-0.60	0.32	0.25	FALSE
10	GTEx	Cells Transformed fibroblasts	PRPS1P2	0.09	0.11	enet	8	0.13	9.6e-10	5.6	5.5	4.3e-08	-0.65	0.94	0.06	FALSE
11	GTEx	Colon Transverse	PRPS1P2	0.11	0.10	lasso	1	0.08	1.8e-04	5.6	5.6	1.9e-08	-0.68	0.63	0.06	FALSE
12	GTEx	Esophagus Mucosa	PPP6C	0.07	0.07	enet	21	0.08	7.1e-06	5.3	-5.9	3.8e-09	0.67	0.95	0.04	FALSE
13	GTEx	Esophagus Mucosa	PRPS1P2	0.07	0.08	lasso	3	0.07	1.5e-05	5.5	5.8	7.9e-09	-0.67	0.50	0.42	FALSE
14	GTEx	Esophagus Muscularis	OLFML2A	0.08	0.00	enet	27	0.00	4.9e-01	5.4	5.6	1.9e-08	-0.50	0.07	0.27	FALSE
15	GTEx	Muscle Skeletal	PPP6C	0.03	0.03	enet	6	0.01	3.0e-02	5.4	-5.4	7.4e-08	0.68	0.48	0.13	FALSE
16	GTEx	Muscle Skeletal	GAPVD1	0.13	0.10	lasso	3	0.09	4.7e-09	-6.7	6.7	1.9e-11	-0.95	0.02	0.98	FALSE
17	GTEx	Nerve Tibial	GAPVD1	0.17	0.08	lasso	10	0.10	9.3e-08	5.3	-6.6	5.1e-11	0.84	0.13	0.87	FALSE
18	GTEx	Nerve Tibial	PRPS1P2	0.11	0.11	enet	9	0.10	1.4e-07	3.9	5.3	1.3e-07	-0.63	0.98	0.02	FALSE
19	GTEx	Ovary	PRPS1P2	0.14	0.14	lasso	2	0.05	2.9e-02	5.4	5.2	1.9e-07	-0.68	0.14	0.30	FALSE
20	GTEx	Pancreas	PRPS1P2	0.16	0.13	lasso	6	0.12	8.7e-06	5.5	5.6	1.7e-08	-0.67	0.85	0.11	FALSE
21	GTEx	Skin Sun Exposed Lower leg	GAPVD1	0.04	0.01	lasso	4	0.01	3.8e-02	5.5	-6.0	1.6e-09	0.77	0.20	0.70	FALSE
22	GTEx	Spleen	PRPS1P2	0.18	0.02	lasso	4	0.04	3.9e-02	4.0	5.4	6.4e-08	-0.63	0.10	0.14	FALSE
23	GTEx	Thyroid	GAPVD1	0.05	0.05	enet	13	0.01	6.6e-02	-6.7	-6.9	5.5e-12	0.96	0.02	0.98	FALSE
24	GTEx	Thyroid	PRPS1P2	0.08	0.09	enet	18	0.07	4.0e-06	5.5	5.6	1.8e-08	-0.72	0.91	0.09	FALSE
25	YFS	Blood	RABEPK	0.12	0.21	bslmm	317	0.22	2.4e-71	5.6	-5.6	1.7e-08	0.67	0.97	0.03	FALSE
26	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PPP6C	0.07	0.08	lasso	3	0.09	5.4e-10	5.6	-5.5	3.2e-08	0.68	0.02	0.98	FALSE
27	The Cancer Genome Atlas	Brain Lower Grade Glioma	PPP6C	0.02	0.02	lasso	2	0.01	1.5e-02	5.6	-5.5	4.1e-08	0.68	0.02	0.68	FALSE
28	The Cancer Genome Atlas	Lung Adenocarcinoma	PPP6C	0.02	0.02	lasso	4	0.02	7.6e-04	5.5	-5.5	2.8e-08	0.67	0.02	0.96	FALSE
29	The Cancer Genome Atlas	Prostate Adenocarcinoma	GAPVD1	0.02	0.04	enet	4	0.01	9.8e-03	-6.9	6.9	3.9e-12	-0.97	0.02	0.92	TRUE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	PPP6C	0.06	0.08	lasso	7	0.07	1.8e-07	5.5	-5.4	8.4e-08	0.64	0.02	0.98	FALSE
31	The Cancer Genome Atlas	Stomach Adenocarcinoma	PPP6C	0.05	0.04	blup	46	0.03	3.8e-03	5.5	-5.3	1.4e-07	0.68	0.02	0.96	FALSE
32	The Cancer Genome Atlas	Thyroid Carcinoma	PPP6C	0.08	0.13	enet	9	0.13	5.5e-13	5.5	-5.5	4.0e-08	0.69	0.03	0.97	FALSE