Best TWAS P=5.04e-09 · Best GWAS P=7.18e-10 conditioned to 0.778
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | BTBD8 | 0.06 | 0.00 | bslmm | 441 | 0.02 | 1.3e-03 | 3.0 | -5.8 | 5.0e-09 | -0.23 | 0.01 | 0.03 | TRUE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | FAM69A | 0.25 | 0.06 | lasso | 4 | 0.05 | 1.2e-05 | 5.6 | 5.6 | 2.2e-08 | 0.84 | 0.07 | 0.91 | TRUE |