TWAS
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Models
Genes
Traits
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Traits
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Trunk fat-free mass
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chr1:91,848,784-93,672,688
Best TWAS P=5.04e-09 · Best GWAS P=7.18e-10 conditioned to 0.778
92M
92.5M
93M
93.5M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
BTBD8
0.06
0.00
bslmm
441
0.02
1.3e-03
3.0
-5.8
5.0e-09
-0.23
0.01
0.03
TRUE
2
The Cancer Genome Atlas
Thyroid Carcinoma
FAM69A
0.25
0.06
lasso
4
0.05
1.2e-05
5.6
5.6
2.2e-08
0.84
0.07
0.91
TRUE