Best TWAS P=6.24e-09 · Best GWAS P=5.78e-12 conditioned to 9.52e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | C1orf54 | 0.06 | 0.02 | enet | 13 | 0.02 | 1.2e-05 | 5.1 | -5.8 | 6.2e-09 | -0.14 | 0.00 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | C1orf54 | 0.04 | 0.04 | lasso | 2 | 0.03 | 2.0e-04 | 5.1 | -5.3 | 1.3e-07 | -0.47 | 0.00 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | C1orf54 | 0.06 | 0.03 | lasso | 1 | 0.03 | 1.3e-04 | 5.1 | -5.1 | 2.7e-07 | -0.48 | 0.00 | 0.93 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MRPS21 | 0.13 | 0.13 | enet | 10 | 0.13 | 1.7e-14 | -4.3 | 5.5 | 3.1e-08 | 0.38 | 0.05 | 0.91 | FALSE |