TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Trunk fat-free mass
:
←
→
chr11:29,646,947-31,288,160
Best TWAS P=6.33e-11 · Best GWAS P=2.96e-13 conditioned to 0.000146
29.6M
29.8M
30M
30.2M
30.4M
30.6M
30.8M
31M
31.2M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
5
ROSMAP
Brain Pre-frontal Cortex
MPPED2
0.25
0.29
lasso
7
0.29
4.4e-37
6.6
-6.5
6.3e-11
-0.70
0.02
0.98
TRUE
4
GTEx
Pituitary
ARL14EP
0.30
0.28
lasso
4
0.22
3.0e-06
6.2
-6.1
1.4e-09
-0.58
0.08
0.84
FALSE
3
GTEx
Esophagus Muscularis
ARL14EP
0.18
0.20
lasso
8
0.19
9.5e-12
5.4
-6.0
1.9e-09
-0.47
0.95
0.05
FALSE
1
GTEx
Brain Cerebellum
ARL14EP
0.33
0.25
lasso
10
0.26
3.7e-08
5.2
-5.5
4.9e-08
-0.56
0.70
0.28
FALSE
2
GTEx
Esophagus Gastroesophageal Junction
ARL14EP
0.15
0.14
lasso
3
0.11
1.2e-04
5.2
-5.3
1.1e-07
-0.56
0.45
0.24
FALSE