[Hub]/) : Traits : Trunk fat-free mass :

chr11:26,818,083-29,054,545

Best TWAS P=6.29e-15 · Best GWAS P=9.63e-20 conditioned to 4.96e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous LIN7C 0.08 0.06 lasso 1 0.04 4.1e-04 7.5 7.5 7.1e-14 0.63 0.75 0.13 FALSE
2 GTEx Cells Transformed fibroblasts LIN7C 0.26 0.22 lasso 6 0.25 1.4e-18 7.5 6.6 4.5e-11 0.62 1.00 0.00 FALSE
3 GTEx Esophagus Muscularis LIN7C 0.14 0.08 enet 11 0.07 5.4e-05 3.7 5.8 6.8e-09 0.60 0.66 0.19 FALSE
4 GTEx Liver METTL15 0.18 0.05 lasso 3 0.09 1.9e-03 0.2 -5.9 2.8e-09 -0.68 0.02 0.80 FALSE
5 GTEx Thyroid LIN7C 0.08 0.04 lasso 4 0.04 6.0e-04 7.5 7.5 6.9e-14 0.69 0.51 0.37 FALSE
6 NTR Blood LIN7C 0.01 0.00 lasso 3 0.01 2.2e-03 8.0 -7.8 6.3e-15 -0.72 0.07 0.87 TRUE
7 The Cancer Genome Atlas Colon Adenocarcinoma LIN7C 0.10 0.03 blup 32 0.08 2.8e-05 7.7 5.8 8.9e-09 0.57 0.01 0.94 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LIN7C 0.05 0.02 lasso 3 0.03 2.9e-04 7.8 7.3 2.0e-13 0.63 0.00 0.98 FALSE