[Hub]/) : Traits : Trunk fat-free mass :

chr11:64,407,419-65,817,307

Best TWAS P=2.31e-12 · Best GWAS P=1.05e-10 conditioned to 0.00107

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Colon Transverse DPF2 0.19 0.01 lasso 4 0.05 1.6e-03 4.9 7.0 2.3e-12 0.52 0.07 0.29 TRUE
2 GTEx Esophagus Mucosa DPF2 0.12 0.02 lasso 4 0.03 6.2e-03 -4.5 5.6 2.1e-08 0.10 0.12 0.05 FALSE
3 GTEx Testis DPF2 0.20 0.09 lasso 7 0.06 9.5e-04 -4.3 5.4 7.9e-08 0.09 0.15 0.09 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma POLA2 0.01 0.01 blup 34 0.02 2.6e-04 -4.7 5.2 1.5e-07 0.07 0.09 0.86 FALSE
5 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma POLA2 0.05 0.02 blup 36 0.05 2.2e-03 -4.5 5.3 8.7e-08 0.08 0.03 0.65 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DPF2 0.03 0.03 lasso 2 0.03 5.6e-04 -5.2 5.4 7.6e-08 0.11 0.00 0.93 FALSE
7 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma POLA2 0.04 0.01 lasso 3 0.02 8.7e-04 -5.0 5.1 2.9e-07 0.07 0.13 0.68 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DPF2 0.07 0.04 blup 28 0.04 2.9e-05 -5.2 5.7 1.4e-08 0.20 0.00 0.98 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma DPF2 0.03 0.02 blup 28 0.02 1.2e-03 -5.2 6.1 1.3e-09 0.17 0.00 0.95 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CAPN1 0.03 0.02 blup 39 0.02 2.1e-03 -5.6 -6.7 1.8e-11 -0.14 0.00 0.96 FALSE
11 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma POLA2 0.12 0.03 enet 9 0.05 2.5e-04 -5.2 5.9 2.8e-09 0.14 0.03 0.58 FALSE
12 The Cancer Genome Atlas Soft Tissue Sarcoma POLA2 0.09 0.06 blup 34 0.08 1.4e-05 -5.7 6.0 2.7e-09 0.10 0.01 0.98 FALSE
13 The Cancer Genome Atlas Stomach Adenocarcinoma NEAT1 0.09 0.06 enet 6 0.09 5.8e-07 2.2 5.2 2.6e-07 0.87 0.01 0.99 FALSE
14 The Cancer Genome Atlas Testicular Germ Cell Tumors POLA2 0.12 0.03 blup 36 0.05 6.8e-03 -4.7 5.2 2.5e-07 0.08 0.04 0.30 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma DPF2 0.05 0.02 blup 29 0.03 3.7e-04 -5.2 6.1 1.0e-09 0.19 0.00 0.93 FALSE