Best TWAS P=6.02e-23 · Best GWAS P=3.9e-51 conditioned to 3.52e-24
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Male) | MRPL42 | 0.21 | -0.01 | lasso | 2 | -0.01 | 6.0e-01 | 10.0 | -9.9 | 6.0e-23 | -0.48 | 0.05 | 0.06 | TRUE |
| 2 | GTEx | Muscle Skeletal | MRPL42 | 0.07 | 0.02 | lasso | 3 | 0.04 | 1.5e-04 | -5.2 | -5.3 | 1.0e-07 | -0.17 | 0.69 | 0.01 | FALSE |
| 3 | NTR | Blood | SOCS2 | 0.04 | 0.02 | bslmm | 454 | 0.02 | 6.5e-08 | 7.6 | 5.2 | 2.5e-07 | -0.22 | 1.00 | 0.00 | FALSE |
| 4 | YFS | Blood | SOCS2 | 0.06 | 0.04 | bslmm | 444 | 0.04 | 1.7e-12 | 7.5 | 8.8 | 1.9e-18 | 0.01 | 1.00 | 0.00 | TRUE |
| 5 | YFS | Blood | UBE2N | 0.02 | 0.00 | bslmm | 424 | 0.01 | 3.6e-03 | 12.9 | 5.8 | 7.2e-09 | 0.38 | 0.06 | 0.26 | TRUE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | MRPL42 | 0.07 | 0.03 | blup | 49 | 0.03 | 1.4e-04 | -3.3 | 5.5 | 4.2e-08 | 0.21 | 0.28 | 0.55 | FALSE |