[Hub]/) : Traits : Trunk fat-free mass : ← →

chr13:49,409,343-52,109,040

Best TWAS P=8.72e-31 · Best GWAS P=1.69e-66 conditioned to 0

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
26	NTR	Blood	DLEU7	0.07	0.02	enet	22	0.06	1.3e-19	-7.79	-11.5	8.7e-31	0.61	0.11	0.89	TRUE
17	GTEx	Nerve Tibial	DLEU2	0.11	0.05	lasso	3	0.02	7.8e-03	9.22	9.5	1.7e-21	-0.11	0.51	0.02	TRUE
35	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	EBPL	0.28	0.18	blup	59	0.19	4.3e-08	6.25	-7.5	8.2e-14	0.06	0.01	0.98	TRUE
1	CommonMind	Brain Pre-frontal Cortex	DLEU7	0.05	0.00	blup	581	0.02	1.6e-03	1.48	7.4	1.1e-13	-0.46	0.08	0.21	TRUE
24	GTEx	Thyroid	EBPL	0.36	0.14	enet	33	0.30	5.1e-23	6.14	-6.9	4.3e-12	0.08	1.00	0.00	TRUE
3	CommonMind	Brain Pre-frontal Cortex	TRIM13	0.15	0.04	lasso	5	0.12	1.1e-14	8.98	-6.9	4.9e-12	0.22	1.00	0.00	TRUE
37	The Cancer Genome Atlas	Stomach Adenocarcinoma	EBPL	0.10	0.07	enet	7	0.08	2.8e-06	8.27	-6.6	4.2e-11	0.12	0.00	1.00	TRUE
22	GTEx	Spleen	RCBTB1	0.37	0.02	lasso	5	0.04	3.5e-02	1.19	-6.4	1.2e-10	0.01	0.04	0.10	TRUE
27	ROSMAP	Brain Pre-frontal Cortex	EBPL	0.43	0.28	lasso	8	0.43	7.3e-60	6.14	-6.0	2.0e-09	0.03	1.00	0.00	TRUE
33	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DLEU2	0.03	0.01	blup	61	0.02	2.4e-03	9.10	9.0	1.5e-19	-0.10	0.01	0.96	FALSE
39	The Cancer Genome Atlas	Thyroid Carcinoma	TRIM13	0.04	0.00	blup	26	0.02	8.5e-03	9.26	-7.8	8.4e-15	0.06	0.00	0.46	FALSE
23	GTEx	Testis	EBPL	0.33	0.17	lasso	6	0.24	8.4e-11	6.45	-7.7	1.6e-14	0.03	1.00	0.00	FALSE
34	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	EBPL	0.21	0.09	enet	10	0.13	4.9e-06	8.27	-7.2	8.9e-13	0.07	0.00	1.00	FALSE
18	GTEx	Pancreas	EBPL	0.18	0.10	enet	5	0.09	1.6e-04	8.27	-7.1	1.2e-12	0.07	0.38	0.04	FALSE
9	GTEx	Brain Cerebellum	EBPL	0.50	0.30	enet	23	0.36	1.8e-11	8.27	-7.1	1.3e-12	0.05	0.86	0.01	FALSE
21	GTEx	Skin Sun Exposed Lower leg	EBPL	0.28	0.21	lasso	5	0.20	2.5e-16	6.68	-6.9	5.7e-12	0.02	1.00	0.00	FALSE
36	The Cancer Genome Atlas	Prostate Adenocarcinoma	EBPL	0.08	0.01	blup	59	0.04	6.4e-05	6.25	-6.9	7.1e-12	0.04	0.01	0.89	FALSE
2	CommonMind	Brain Pre-frontal Cortex	EBPL	0.34	0.16	bslmm	399	0.33	2.5e-41	0.33	-6.8	9.8e-12	0.04	1.00	0.00	FALSE
5	GTEx	Artery Aorta	EBPL	0.43	0.20	enet	78	0.28	8.1e-16	6.22	-6.8	1.0e-11	0.14	1.00	0.00	FALSE
10	GTEx	Brain Cortex	EBPL	0.36	0.08	enet	24	0.14	1.5e-04	8.27	-6.6	3.8e-11	0.14	0.18	0.15	FALSE
31	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	EBPL	0.27	0.16	blup	59	0.22	1.0e-12	-1.41	-6.5	6.5e-11	0.06	0.29	0.71	FALSE
4	GTEx	Adipose Visceral Omentum	EBPL	0.27	0.03	enet	17	0.20	1.4e-10	8.27	-6.5	8.1e-11	0.09	0.88	0.01	FALSE
13	GTEx	Esophagus Gastroesophageal Junction	EBPL	0.27	0.24	enet	14	0.26	4.6e-10	6.14	-6.5	1.1e-10	0.02	1.00	0.00	FALSE
29	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DLEU2	0.08	0.02	lasso	2	0.01	1.6e-02	-5.83	6.4	1.5e-10	0.02	0.13	0.25	FALSE
15	GTEx	Esophagus Muscularis	EBPL	0.39	0.16	enet	36	0.29	9.2e-18	6.22	-6.2	5.8e-10	0.03	1.00	0.00	FALSE
38	The Cancer Genome Atlas	Thyroid Carcinoma	EBPL	0.28	0.10	enet	17	0.26	7.7e-25	-1.41	-5.9	3.1e-09	0.02	0.24	0.76	FALSE
6	GTEx	Artery Coronary	EBPL	0.48	0.03	enet	99	0.12	9.7e-05	8.27	-5.8	5.5e-09	0.04	0.29	0.04	FALSE
30	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EBPL	0.21	0.14	enet	15	0.19	3.6e-21	-1.41	-5.8	6.0e-09	0.08	1.00	0.00	FALSE
20	GTEx	Skin Not Sun Exposed Suprapubic	EBPL	0.34	0.26	enet	12	0.30	4.0e-17	6.22	-5.8	6.6e-09	0.00	1.00	0.00	FALSE
8	GTEx	Brain Cerebellar Hemisphere	EBPL	0.54	0.32	enet	17	0.34	1.2e-09	0.33	-5.8	7.0e-09	0.08	0.65	0.02	FALSE
19	GTEx	Pituitary	EBPL	0.44	0.32	enet	29	0.37	3.1e-10	6.22	-5.8	7.7e-09	-0.02	0.92	0.01	FALSE
11	GTEx	Brain Nucleus accumbens basal ganglia	EBPL	0.25	0.11	enet	21	0.11	7.9e-04	6.25	-5.8	8.7e-09	0.12	0.13	0.09	FALSE
12	GTEx	Brain Putamen basal ganglia	EBPL	0.31	-0.01	enet	18	0.05	2.9e-02	6.25	-5.7	9.3e-09	0.08	0.06	0.13	FALSE
25	METSIM	Adipose	EBPL	0.32	0.12	lasso	7	0.27	1.4e-39	6.45	-5.7	1.0e-08	0.03	1.00	0.00	FALSE
16	GTEx	Heart Atrial Appendage	EBPL	0.17	0.04	lasso	5	0.05	2.2e-03	8.27	-5.7	1.2e-08	0.07	0.26	0.03	FALSE
28	The Cancer Genome Atlas	Breast Invasive Carcinoma	EBPL	0.07	0.03	enet	11	0.06	2.1e-12	6.25	-5.7	1.3e-08	0.04	0.06	0.94	FALSE
7	GTEx	Brain Caudate basal ganglia	EBPL	0.41	0.06	lasso	7	0.12	2.1e-04	6.14	-5.7	1.4e-08	0.02	0.11	0.17	FALSE
32	The Cancer Genome Atlas	Lung Adenocarcinoma	EBPL	0.07	0.02	blup	59	0.03	8.9e-05	0.33	-5.2	1.6e-07	0.08	0.02	0.81	FALSE
14	GTEx	Esophagus Mucosa	EBPL	0.44	0.16	enet	35	0.24	2.6e-16	-4.62	-5.2	2.1e-07	0.00	1.00	0.00	FALSE