Best TWAS P=4.75e-15 · Best GWAS P=1.93e-14 conditioned to 0.157
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | EDNRB | 0.05 | 0.03 | bslmm | 465 | 0.04 | 3.1e-06 | -6.2 | 6.3 | 3.6e-10 | -0.61 | 0.39 | 0.58 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | EDNRB | 0.02 | 0.00 | blup | 60 | 0.00 | 3.1e-02 | -7.7 | 7.8 | 4.8e-15 | -0.90 | 0.00 | 0.77 | TRUE |