Best TWAS P=8.71e-10 · Best GWAS P=1.65e-24 conditioned to 5.66e-18
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cortex | HAPLN3 | 0.40 | -0.01 | lasso | 5 | -0.01 | 6.0e-01 | -4.0 | -5.2 | 2.2e-07 | -0.04 | 0.05 | 0.12 | TRUE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | HAPLN3 | 0.14 | 0.04 | lasso | 4 | 0.08 | 1.7e-05 | 1.5 | -6.1 | 8.7e-10 | 0.43 | 0.05 | 0.58 | TRUE |