[Hub]/) : Traits : Trunk fat-free mass :

chr16:81,485,946-82,901,701

Best TWAS P=1.2e-09 · Best GWAS P=2.25e-11 conditioned to 2.74e-11

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum MPHOSPH6 0.32 0.14 lasso 4 0.17 3.5e-09 5.1 5.5 4.7e-08 -0.01 0.01 0.99 FALSE
2 GTEx Adrenal Gland MPHOSPH6 0.34 0.25 lasso 3 0.26 8.4e-10 5.7 5.3 1.3e-07 -0.01 0.00 1.00 FALSE
3 GTEx Artery Tibial MPHOSPH6 0.36 0.24 enet 9 0.27 1.9e-21 5.7 5.6 2.1e-08 -0.01 0.00 1.00 FALSE
4 GTEx Brain Cerebellar Hemisphere MPHOSPH6 0.49 0.30 enet 12 0.31 8.5e-09 5.7 5.3 9.5e-08 -0.01 0.01 0.99 FALSE
5 GTEx Brain Cerebellum MPHOSPH6 0.40 0.36 enet 10 0.39 1.8e-12 4.4 5.2 1.5e-07 -0.03 0.02 0.98 FALSE
6 GTEx Colon Transverse MPHOSPH6 0.21 0.16 lasso 3 0.17 1.4e-08 5.7 5.6 2.1e-08 -0.01 0.00 1.00 FALSE
7 GTEx Esophagus Gastroesophageal Junction MPHOSPH6 0.43 0.19 enet 30 0.19 1.8e-07 5.5 5.2 1.8e-07 -0.02 0.01 0.99 FALSE
8 GTEx Esophagus Muscularis MPHOSPH6 0.36 0.23 lasso 7 0.20 1.7e-12 5.7 5.7 1.1e-08 -0.01 0.00 1.00 FALSE
9 GTEx Heart Atrial Appendage MPHOSPH6 0.33 0.19 enet 27 0.21 5.4e-10 5.7 5.2 2.3e-07 -0.02 0.01 0.99 FALSE
10 GTEx Heart Left Ventricle MPHOSPH6 0.28 0.24 lasso 3 0.24 8.9e-13 5.7 5.7 1.1e-08 -0.01 0.00 1.00 FALSE
11 GTEx Lung MPHOSPH6 0.16 0.10 lasso 4 0.11 8.3e-09 5.7 5.5 3.9e-08 -0.02 0.01 0.99 FALSE
12 GTEx Muscle Skeletal MPHOSPH6 0.27 0.19 lasso 7 0.23 1.4e-22 5.7 5.2 1.9e-07 -0.01 0.00 1.00 FALSE
13 GTEx Nerve Tibial MPHOSPH6 0.40 0.22 lasso 7 0.28 1.0e-19 5.7 6.0 1.9e-09 -0.02 0.00 1.00 FALSE
14 GTEx Stomach MPHOSPH6 0.41 0.10 lasso 7 0.09 3.5e-05 4.8 6.1 1.2e-09 0.00 0.01 0.99 TRUE
15 GTEx Testis MPHOSPH6 0.52 0.32 lasso 11 0.35 2.0e-16 5.7 5.7 1.3e-08 -0.02 0.00 1.00 FALSE
16 GTEx Thyroid MPHOSPH6 0.31 0.21 lasso 4 0.26 4.7e-20 5.1 5.5 3.3e-08 -0.01 0.01 0.99 FALSE
17 METSIM Adipose MPHOSPH6 0.12 0.07 bslmm 741 0.08 2.0e-11 5.5 5.2 2.4e-07 -0.05 0.00 1.00 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma MPHOSPH6 0.07 0.03 lasso 4 0.06 8.0e-07 5.6 5.2 1.6e-07 -0.04 0.01 0.98 FALSE
19 The Cancer Genome Atlas Thyroid Carcinoma MPHOSPH6 0.18 0.16 lasso 3 0.16 5.1e-15 5.7 5.6 2.0e-08 -0.02 0.00 1.00 FALSE