[Hub]/) : Traits : Trunk fat-free mass :

chr16:88,074,533-90,172,696

Best TWAS P=6.17e-15 · Best GWAS P=7.31e-18 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CTU2 0.10 0.07 lasso 5 0.08 4.0e-10 -4.8 5.8 7.8e-09 -0.43 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex SPG7 0.14 0.06 blup 445 0.10 3.2e-12 6.4 -6.7 1.6e-11 -0.02 0.01 0.99 FALSE
3 GTEx Artery Aorta RPL13 0.19 0.20 lasso 5 0.17 1.7e-09 6.1 -6.7 2.5e-11 0.05 0.02 0.98 FALSE
4 GTEx Artery Tibial CHMP1A 0.21 0.06 enet 34 0.11 7.3e-09 3.2 5.2 1.5e-07 -0.09 0.12 0.04 FALSE
5 GTEx Breast Mammary Tissue RPL13 0.09 0.05 enet 7 0.04 5.3e-03 7.0 -6.3 2.9e-10 0.00 0.02 0.94 FALSE
6 GTEx Cells Transformed fibroblasts RPL13 0.10 0.08 enet 8 0.09 3.7e-07 5.4 -6.5 6.2e-11 0.09 0.03 0.97 FALSE
7 GTEx Cells Transformed fibroblasts RP11-104N10.1 0.07 0.10 lasso 2 0.08 8.3e-07 -5.8 -5.8 8.0e-09 -0.17 0.80 0.19 FALSE
8 GTEx Colon Sigmoid RPL13 0.17 0.18 lasso 1 0.16 3.1e-06 6.1 -6.1 1.3e-09 0.08 0.01 0.98 FALSE
9 GTEx Colon Sigmoid CDK10 0.37 0.12 lasso 8 0.22 2.2e-08 4.8 -6.7 2.8e-11 -0.21 0.51 0.16 FALSE
10 GTEx Colon Sigmoid RP11-104N10.1 0.14 0.00 lasso 2 0.02 8.3e-02 -6.0 -6.0 2.0e-09 -0.17 0.10 0.18 TRUE
11 GTEx Colon Transverse RPL13 0.23 0.17 lasso 4 0.16 3.7e-08 6.8 -7.8 6.2e-15 0.01 0.01 0.99 TRUE
12 GTEx Esophagus Muscularis RPL13 0.17 0.12 lasso 3 0.11 2.4e-07 6.8 -7.1 1.3e-12 0.06 0.01 0.99 FALSE
13 GTEx Esophagus Muscularis CDK10 0.24 0.11 enet 19 0.14 4.3e-09 4.8 -5.8 7.1e-09 -0.21 0.99 0.00 TRUE
14 GTEx Muscle Skeletal RPL13 0.10 0.09 lasso 5 0.10 3.3e-10 6.1 -6.4 1.8e-10 0.08 0.02 0.98 FALSE
15 GTEx Muscle Skeletal CDK10 0.17 0.12 lasso 6 0.10 9.2e-10 4.8 -5.5 3.2e-08 -0.17 1.00 0.00 FALSE
16 GTEx Muscle Skeletal SPG7 0.24 0.22 lasso 5 0.23 8.9e-23 -5.7 -6.9 5.8e-12 -0.11 0.83 0.17 TRUE
17 GTEx Nerve Tibial RPL13 0.10 0.07 lasso 3 0.07 2.0e-05 6.4 -6.0 2.1e-09 0.09 0.05 0.95 FALSE
18 GTEx Pituitary VPS9D1-AS1 0.21 -0.01 lasso 9 -0.01 5.7e-01 4.8 5.2 1.6e-07 0.15 0.04 0.33 FALSE
19 GTEx Skin Not Sun Exposed Suprapubic RPL13 0.16 0.15 lasso 4 0.15 2.0e-08 6.4 -6.5 8.2e-11 0.09 0.05 0.95 FALSE
20 GTEx Skin Not Sun Exposed Suprapubic RP11-104N10.1 0.11 0.04 lasso 4 0.03 5.2e-03 -5.9 -5.5 2.8e-08 -0.13 0.14 0.48 TRUE
21 GTEx Skin Sun Exposed Lower leg RPL13 0.11 0.13 enet 7 0.12 1.7e-10 5.8 -6.1 1.3e-09 0.06 0.09 0.91 TRUE
22 GTEx Skin Sun Exposed Lower leg SPG7 0.09 0.05 lasso 2 0.03 1.5e-03 6.8 -6.6 3.1e-11 0.08 0.02 0.98 FALSE
23 GTEx Skin Sun Exposed Lower leg VPS9D1-AS1 0.18 0.04 lasso 5 0.06 1.2e-05 4.6 5.6 2.6e-08 0.07 0.91 0.00 FALSE
24 GTEx Small Intestine Terminal Ileum VPS9D1 0.34 0.04 enet 11 0.11 2.4e-03 4.8 5.2 1.5e-07 0.16 0.15 0.06 FALSE
25 GTEx Small Intestine Terminal Ileum AC092143.1 0.25 0.02 lasso 18 0.02 9.8e-02 -5.4 -5.4 5.8e-08 -0.12 0.06 0.30 FALSE
26 GTEx Stomach CDK10 0.35 0.12 enet 12 0.22 6.4e-11 4.9 -5.7 9.4e-09 -0.20 0.84 0.07 FALSE
27 GTEx Testis RPL13 0.25 0.22 lasso 5 0.21 1.6e-09 6.1 -6.0 2.6e-09 0.09 0.03 0.97 TRUE
28 GTEx Testis RP5-1142A6.2 0.21 0.13 lasso 4 0.12 7.2e-06 -6.2 -7.2 4.2e-13 0.60 0.15 0.34 TRUE
29 GTEx Thyroid RPL13 0.13 0.05 enet 10 0.06 1.4e-05 6.5 -7.6 2.1e-14 -0.02 0.02 0.98 FALSE
30 GTEx Whole Blood SPG7 0.06 0.05 lasso 3 0.05 3.9e-05 6.4 -7.1 9.9e-13 0.01 0.06 0.90 FALSE
31 GTEx Whole Blood CTD-2555A7.3 0.10 0.00 lasso 5 0.01 1.0e-01 2.4 5.4 7.5e-08 -0.19 0.13 0.10 FALSE
32 METSIM Adipose CHMP1A 0.27 0.05 lasso 9 0.07 1.3e-10 3.2 5.6 2.3e-08 0.02 0.91 0.04 FALSE
33 METSIM Adipose RPL13 0.05 0.05 enet 5 0.05 1.0e-07 6.5 -6.5 1.0e-10 0.07 0.02 0.98 FALSE
34 NTR Blood RPL13 0.02 0.01 bslmm 365 0.01 5.9e-05 6.8 5.7 1.3e-08 -0.12 0.01 0.98 FALSE
35 YFS Blood DEF8 0.12 0.06 bslmm 285 0.10 9.6e-31 2.7 5.6 2.6e-08 -0.03 1.00 0.00 TRUE
36 YFS Blood SPG7 0.08 0.11 lasso 6 0.11 6.9e-34 -5.8 -6.0 2.0e-09 -0.18 0.81 0.19 FALSE
37 The Cancer Genome Atlas Bladder Urothelial Carcinoma CTU2 0.06 0.03 blup 67 0.03 1.3e-03 -1.1 5.5 4.3e-08 -0.41 0.05 0.09 FALSE
38 The Cancer Genome Atlas Bladder Urothelial Carcinoma SPG7 0.05 0.03 lasso 3 0.03 1.8e-03 6.4 -6.3 3.4e-10 0.08 0.03 0.83 FALSE
39 The Cancer Genome Atlas Esophageal Carcinoma RPL13 0.14 0.07 lasso 3 0.04 2.6e-02 6.4 -6.6 3.4e-11 0.07 0.01 0.80 FALSE
40 The Cancer Genome Atlas Glioblastoma Multiforme SNAI3 0.19 0.06 enet 7 0.12 1.6e-04 3.1 -5.9 4.0e-09 0.44 0.00 0.86 TRUE
41 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SPG7 0.05 0.05 lasso 5 0.05 1.9e-06 6.4 -6.4 1.3e-10 0.08 0.04 0.96 FALSE
42 The Cancer Genome Atlas Brain Lower Grade Glioma SPG7 0.03 0.02 blup 58 0.03 4.1e-04 5.4 -7.0 1.8e-12 -0.01 0.03 0.71 TRUE
43 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RPL13 0.03 0.01 blup 41 0.02 8.5e-03 6.5 -7.2 7.8e-13 0.01 0.02 0.72 FALSE
44 The Cancer Genome Atlas Pancreatic Adenocarcinoma SPG7 0.11 0.09 lasso 2 0.08 2.5e-04 6.7 -6.7 1.6e-11 0.07 0.02 0.95 FALSE
45 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CDK10 0.20 0.02 enet 15 0.08 5.3e-04 3.2 -5.3 1.0e-07 -0.08 0.00 0.00 FALSE
46 The Cancer Genome Atlas Stomach Adenocarcinoma RPL13 0.04 0.03 blup 41 0.03 2.2e-03 6.1 -7.2 8.6e-13 0.06 0.02 0.86 FALSE
47 The Cancer Genome Atlas Thyroid Carcinoma SPG7 0.10 0.09 lasso 4 0.11 1.9e-10 6.7 -5.5 4.3e-08 0.14 0.01 0.99 FALSE