[Hub]/) : Traits : Trunk fat-free mass : ← →

chr16:88,074,533-90,172,696

Best TWAS P=6.17e-15 · Best GWAS P=7.31e-18 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	GTEx	Colon Transverse	RPL13	0.23	0.17	lasso	4	0.16	3.7e-08	6.8	-7.8	6.2e-15	0.01	0.01	0.99	TRUE
28	GTEx	Testis	RP5-1142A6.2	0.21	0.13	lasso	4	0.12	7.2e-06	-6.2	-7.2	4.2e-13	0.60	0.15	0.34	TRUE
42	The Cancer Genome Atlas	Brain Lower Grade Glioma	SPG7	0.03	0.02	blup	58	0.03	4.1e-04	5.4	-7.0	1.8e-12	-0.01	0.03	0.71	TRUE
16	GTEx	Muscle Skeletal	SPG7	0.24	0.22	lasso	5	0.23	8.9e-23	-5.7	-6.9	5.8e-12	-0.11	0.83	0.17	TRUE
21	GTEx	Skin Sun Exposed Lower leg	RPL13	0.11	0.13	enet	7	0.12	1.7e-10	5.8	-6.1	1.3e-09	0.06	0.09	0.91	TRUE
10	GTEx	Colon Sigmoid	RP11-104N10.1	0.14	0.00	lasso	2	0.02	8.3e-02	-6.0	-6.0	2.0e-09	-0.17	0.10	0.18	TRUE
27	GTEx	Testis	RPL13	0.25	0.22	lasso	5	0.21	1.6e-09	6.1	-6.0	2.6e-09	0.09	0.03	0.97	TRUE
40	The Cancer Genome Atlas	Glioblastoma Multiforme	SNAI3	0.19	0.06	enet	7	0.12	1.6e-04	3.1	-5.9	4.0e-09	0.44	0.00	0.86	TRUE
13	GTEx	Esophagus Muscularis	CDK10	0.24	0.11	enet	19	0.14	4.3e-09	4.8	-5.8	7.1e-09	-0.21	0.99	0.00	TRUE
35	YFS	Blood	DEF8	0.12	0.06	bslmm	285	0.10	9.6e-31	2.7	5.6	2.6e-08	-0.03	1.00	0.00	TRUE
20	GTEx	Skin Not Sun Exposed Suprapubic	RP11-104N10.1	0.11	0.04	lasso	4	0.03	5.2e-03	-5.9	-5.5	2.8e-08	-0.13	0.14	0.48	TRUE
29	GTEx	Thyroid	RPL13	0.13	0.05	enet	10	0.06	1.4e-05	6.5	-7.6	2.1e-14	-0.02	0.02	0.98	FALSE
43	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RPL13	0.03	0.01	blup	41	0.02	8.5e-03	6.5	-7.2	7.8e-13	0.01	0.02	0.72	FALSE
46	The Cancer Genome Atlas	Stomach Adenocarcinoma	RPL13	0.04	0.03	blup	41	0.03	2.2e-03	6.1	-7.2	8.6e-13	0.06	0.02	0.86	FALSE
30	GTEx	Whole Blood	SPG7	0.06	0.05	lasso	3	0.05	3.9e-05	6.4	-7.1	9.9e-13	0.01	0.06	0.90	FALSE
12	GTEx	Esophagus Muscularis	RPL13	0.17	0.12	lasso	3	0.11	2.4e-07	6.8	-7.1	1.3e-12	0.06	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SPG7	0.14	0.06	blup	445	0.10	3.2e-12	6.4	-6.7	1.6e-11	-0.02	0.01	0.99	FALSE
44	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SPG7	0.11	0.09	lasso	2	0.08	2.5e-04	6.7	-6.7	1.6e-11	0.07	0.02	0.95	FALSE
3	GTEx	Artery Aorta	RPL13	0.19	0.20	lasso	5	0.17	1.7e-09	6.1	-6.7	2.5e-11	0.05	0.02	0.98	FALSE
9	GTEx	Colon Sigmoid	CDK10	0.37	0.12	lasso	8	0.22	2.2e-08	4.8	-6.7	2.8e-11	-0.21	0.51	0.16	FALSE
22	GTEx	Skin Sun Exposed Lower leg	SPG7	0.09	0.05	lasso	2	0.03	1.5e-03	6.8	-6.6	3.1e-11	0.08	0.02	0.98	FALSE
39	The Cancer Genome Atlas	Esophageal Carcinoma	RPL13	0.14	0.07	lasso	3	0.04	2.6e-02	6.4	-6.6	3.4e-11	0.07	0.01	0.80	FALSE
6	GTEx	Cells Transformed fibroblasts	RPL13	0.10	0.08	enet	8	0.09	3.7e-07	5.4	-6.5	6.2e-11	0.09	0.03	0.97	FALSE
19	GTEx	Skin Not Sun Exposed Suprapubic	RPL13	0.16	0.15	lasso	4	0.15	2.0e-08	6.4	-6.5	8.2e-11	0.09	0.05	0.95	FALSE
33	METSIM	Adipose	RPL13	0.05	0.05	enet	5	0.05	1.0e-07	6.5	-6.5	1.0e-10	0.07	0.02	0.98	FALSE
41	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SPG7	0.05	0.05	lasso	5	0.05	1.9e-06	6.4	-6.4	1.3e-10	0.08	0.04	0.96	FALSE
14	GTEx	Muscle Skeletal	RPL13	0.10	0.09	lasso	5	0.10	3.3e-10	6.1	-6.4	1.8e-10	0.08	0.02	0.98	FALSE
5	GTEx	Breast Mammary Tissue	RPL13	0.09	0.05	enet	7	0.04	5.3e-03	7.0	-6.3	2.9e-10	0.00	0.02	0.94	FALSE
38	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SPG7	0.05	0.03	lasso	3	0.03	1.8e-03	6.4	-6.3	3.4e-10	0.08	0.03	0.83	FALSE
8	GTEx	Colon Sigmoid	RPL13	0.17	0.18	lasso	1	0.16	3.1e-06	6.1	-6.1	1.3e-09	0.08	0.01	0.98	FALSE
36	YFS	Blood	SPG7	0.08	0.11	lasso	6	0.11	6.9e-34	-5.8	-6.0	2.0e-09	-0.18	0.81	0.19	FALSE
17	GTEx	Nerve Tibial	RPL13	0.10	0.07	lasso	3	0.07	2.0e-05	6.4	-6.0	2.1e-09	0.09	0.05	0.95	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CTU2	0.10	0.07	lasso	5	0.08	4.0e-10	-4.8	5.8	7.8e-09	-0.43	1.00	0.00	FALSE
7	GTEx	Cells Transformed fibroblasts	RP11-104N10.1	0.07	0.10	lasso	2	0.08	8.3e-07	-5.8	-5.8	8.0e-09	-0.17	0.80	0.19	FALSE
26	GTEx	Stomach	CDK10	0.35	0.12	enet	12	0.22	6.4e-11	4.9	-5.7	9.4e-09	-0.20	0.84	0.07	FALSE
34	NTR	Blood	RPL13	0.02	0.01	bslmm	365	0.01	5.9e-05	6.8	5.7	1.3e-08	-0.12	0.01	0.98	FALSE
32	METSIM	Adipose	CHMP1A	0.27	0.05	lasso	9	0.07	1.3e-10	3.2	5.6	2.3e-08	0.02	0.91	0.04	FALSE
23	GTEx	Skin Sun Exposed Lower leg	VPS9D1-AS1	0.18	0.04	lasso	5	0.06	1.2e-05	4.6	5.6	2.6e-08	0.07	0.91	0.00	FALSE
15	GTEx	Muscle Skeletal	CDK10	0.17	0.12	lasso	6	0.10	9.2e-10	4.8	-5.5	3.2e-08	-0.17	1.00	0.00	FALSE
37	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CTU2	0.06	0.03	blup	67	0.03	1.3e-03	-1.1	5.5	4.3e-08	-0.41	0.05	0.09	FALSE
47	The Cancer Genome Atlas	Thyroid Carcinoma	SPG7	0.10	0.09	lasso	4	0.11	1.9e-10	6.7	-5.5	4.3e-08	0.14	0.01	0.99	FALSE
25	GTEx	Small Intestine Terminal Ileum	AC092143.1	0.25	0.02	lasso	18	0.02	9.8e-02	-5.4	-5.4	5.8e-08	-0.12	0.06	0.30	FALSE
31	GTEx	Whole Blood	CTD-2555A7.3	0.10	0.00	lasso	5	0.01	1.0e-01	2.4	5.4	7.5e-08	-0.19	0.13	0.10	FALSE
45	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CDK10	0.20	0.02	enet	15	0.08	5.3e-04	3.2	-5.3	1.0e-07	-0.08	0.00	0.00	FALSE
4	GTEx	Artery Tibial	CHMP1A	0.21	0.06	enet	34	0.11	7.3e-09	3.2	5.2	1.5e-07	-0.09	0.12	0.04	FALSE
24	GTEx	Small Intestine Terminal Ileum	VPS9D1	0.34	0.04	enet	11	0.11	2.4e-03	4.8	5.2	1.5e-07	0.16	0.15	0.06	FALSE
18	GTEx	Pituitary	VPS9D1-AS1	0.21	-0.01	lasso	9	-0.01	5.7e-01	4.8	5.2	1.6e-07	0.15	0.04	0.33	FALSE