[Hub]/) : Traits : Trunk fat-free mass :

chr16:71,070,698-72,569,466

Best TWAS P=2.35e-09 · Best GWAS P=7.03e-11 conditioned to 1.28e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PHLPP2 0.04 0.01 bslmm 456 0.02 4.7e-04 -4.8 -5.7 9.5e-09 0.32 0.08 0.91 FALSE
2 GTEx Adrenal Gland AP1G1 0.22 0.06 enet 25 0.14 8.0e-06 -6.1 -5.8 8.5e-09 0.38 0.05 0.94 FALSE
3 GTEx Artery Aorta AP1G1 0.10 0.09 lasso 2 0.07 1.3e-04 -5.1 -5.1 3.0e-07 0.41 0.11 0.80 FALSE
4 GTEx Skin Sun Exposed Lower leg AP1G1 0.06 0.00 enet 15 0.01 5.7e-02 -5.4 -5.2 1.7e-07 0.26 0.10 0.78 FALSE
5 GTEx Testis PHLPP2 0.29 0.38 enet 20 0.37 3.0e-17 -6.2 5.9 3.0e-09 -0.39 0.04 0.96 FALSE
6 METSIM Adipose PHLPP2 0.07 0.03 lasso 5 0.06 1.7e-09 4.2 5.6 2.1e-08 -0.30 1.00 0.00 FALSE
7 YFS Blood ATXN1L 0.02 0.02 blup 413 0.02 6.5e-07 3.8 5.5 4.1e-08 -0.42 0.96 0.03 FALSE
8 YFS Blood PHLPP2 0.04 0.03 bslmm 459 0.05 5.5e-16 -6.0 5.9 3.5e-09 -0.33 0.06 0.94 FALSE
9 The Cancer Genome Atlas Esophageal Carcinoma PHLPP2 0.18 0.03 blup 67 0.07 2.9e-03 -6.2 -5.4 7.8e-08 0.33 0.02 0.74 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma AP1G1 0.03 0.03 lasso 4 0.02 2.1e-03 -3.8 -5.3 1.4e-07 0.38 0.02 0.85 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma AP1G1 0.11 0.02 enet 27 0.04 1.2e-04 4.2 -6.0 2.3e-09 0.15 0.08 0.24 TRUE
12 The Cancer Genome Atlas Testicular Germ Cell Tumors PHLPP2 0.11 0.03 lasso 6 0.01 1.2e-01 4.1 5.6 1.7e-08 -0.27 0.03 0.47 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma MARVELD3 0.08 0.01 blup 44 0.06 7.1e-07 -6.1 5.8 7.9e-09 -0.31 0.02 0.97 FALSE