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Traits
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Trunk fat-free mass
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chr2:8,934,921-10,874,671
Best TWAS P=2.2e-09 · Best GWAS P=4.52e-13 conditioned to 1.36e-08
9M
9.5M
10M
10.5M
0
2
4
6
8
10
12
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
ROSMAP
Brain Pre-frontal Cortex
RP11-254F7.2
0.35
0.21
bslmm
562
0.30
1.4e-39
5.0
6.0
2.2e-09
0.05
1.00
0.00
TRUE
1
GTEx
Brain Frontal Cortex BA9
ADAM17
0.20
0.14
lasso
5
0.15
7.8e-05
-5.4
5.4
6.4e-08
0.27
0.51
0.04
TRUE
2
GTEx
Thyroid
GRHL1
0.15
0.04
enet
30
0.02
1.2e-02
-2.0
5.6
2.1e-08
0.02
0.22
0.03
FALSE