Best TWAS P=2.2e-09 · Best GWAS P=4.52e-13 conditioned to 1.36e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | ADAM17 | 0.20 | 0.14 | lasso | 5 | 0.15 | 7.8e-05 | -5.4 | 5.4 | 6.4e-08 | 0.27 | 0.51 | 0.04 | TRUE |
| 2 | GTEx | Thyroid | GRHL1 | 0.15 | 0.04 | enet | 30 | 0.02 | 1.2e-02 | -2.0 | 5.6 | 2.1e-08 | 0.02 | 0.22 | 0.03 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | RP11-254F7.2 | 0.35 | 0.21 | bslmm | 562 | 0.30 | 1.4e-39 | 5.0 | 6.0 | 2.2e-09 | 0.05 | 1.00 | 0.00 | TRUE |