TWAS
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Models
Genes
Traits
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Traits
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Trunk fat-free mass
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chr2:46,021,381-47,782,756
Best TWAS P=7.8e-09 · Best GWAS P=2.42e-09 conditioned to 1.17e-06
46M
46.2M
46.4M
46.6M
46.8M
47M
47.2M
47.4M
47.6M
47.8M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Frontal Cortex BA9
ATP6V1E2
0.4
-0.01
enet
35
0.06
1.4e-02
3.1
-5.8
7.8e-09
0.21
0.11
0.06
TRUE
2
GTEx
Esophagus Gastroesophageal Junction
AC016722.2
0.3
0.07
lasso
4
0.11
7.7e-05
4.0
-5.4
7.3e-08
0.73
0.02
0.93
FALSE