Best TWAS P=1.67e-21 · Best GWAS P=4.04e-23 conditioned to 0.00112
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | EFEMP1 | 0.19 | 0.10 | lasso | 8 | 0.08 | 3.7e-03 | -8.7 | -9.5 | 1.7e-21 | 0.78 | 0.04 | 0.70 | TRUE |
| 2 | GTEx | Stomach | SMEK2 | 0.14 | 0.02 | enet | 19 | 0.04 | 3.9e-03 | -2.5 | -5.6 | 2.4e-08 | 0.08 | 0.10 | 0.04 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | EFEMP1 | 0.29 | 0.14 | enet | 37 | 0.19 | 2.2e-24 | -4.3 | -5.2 | 2.2e-07 | 0.64 | 1.00 | 0.00 | FALSE |