Best TWAS P=2.18e-10 · Best GWAS P=9.36e-10 conditioned to 0.0962
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DHX36 | 0.05 | 0.06 | blup | 357 | 0.05 | 1.3e-06 | -4.4 | -5.2 | 1.6e-07 | -0.49 | 0.97 | 0.03 | FALSE |
| 2 | GTEx | Ovary | ARHGEF26 | 0.14 | 0.03 | enet | 15 | 0.06 | 1.4e-02 | 6.1 | 6.3 | 2.2e-10 | 0.81 | 0.04 | 0.74 | TRUE |
| 3 | GTEx | Pancreas | ARHGEF26 | 0.26 | 0.26 | lasso | 5 | 0.28 | 3.2e-12 | -4.4 | 5.2 | 1.9e-07 | 0.46 | 0.98 | 0.02 | FALSE |