[Hub]/) : Traits : Trunk fat-free mass :

chr3:170,624,266-172,924,003

Best TWAS P=1.13e-20 · Best GWAS P=1.22e-33 conditioned to 1.21e-10

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FNDC3B 0.07 0.06 enet 8 0.05 3.2e-07 -10.0 9.3 1.1e-20 0.04 0.97 0.00 TRUE
2 GTEx Breast Mammary Tissue (Female) PLD1 0.07 -0.01 lasso 1 0.01 2.2e-01 5.7 5.7 1.2e-08 0.01 0.05 0.06 FALSE
3 GTEx Ovary TNFSF10 0.40 0.01 lasso 10 0.05 1.8e-02 1.3 7.3 2.7e-13 0.41 0.03 0.50 TRUE
4 METSIM Adipose FNDC3B 0.09 0.08 lasso 9 0.07 5.0e-11 -3.2 -5.2 2.6e-07 -0.02 1.00 0.00 TRUE
5 YFS Blood TNFSF10 0.09 0.04 bslmm 462 0.08 1.6e-24 7.8 7.2 5.9e-13 0.38 1.00 0.00 TRUE
6 The Cancer Genome Atlas Glioblastoma Multiforme FNDC3B 0.27 0.05 lasso 6 0.08 1.8e-03 4.1 -5.7 9.1e-09 -0.67 0.03 0.58 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FNDC3B 0.07 0.02 enet 6 0.02 3.9e-03 8.6 -8.6 1.2e-17 -0.83 0.01 0.98 TRUE
8 The Cancer Genome Atlas Testicular Germ Cell Tumors TNFSF10 0.17 0.11 lasso 2 0.09 6.0e-04 -5.0 5.1 2.8e-07 0.26 0.03 0.17 FALSE